Growth Metrics

AC Immune (ACIU) Enterprise Value (2014 - 2025)

AC Immune (ACIU) reported Enterprise Value of -$114.3 million for Q4 2025, up 39.47% year-over-year from -$82.0 million in Q4 2024, and up 15.67% on a QoQ basis from -$135.6 million in Q3 2025.

AC Immune (ACIU) has 12 years of Enterprise Value data on file, last reported at -$114.3 million in Q4 2025.

  • Quarterly Enterprise Value rose 39.47% year-over-year to -$114.3 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$114.3 million (up 39.47% YoY) and the FY2025 annual result came in at -$110.2 million, up 41.65% from the prior year.
  • Enterprise Value rose to -$114.3 million in Q4 2025 per ACIU's latest filing, from -$135.6 million in the prior quarter.
  • Across five years, Enterprise Value topped out at $32.8 million in Q2 2021 and bottomed at -$125.9 billion in Q4 2021.
  • The 5-year median for Enterprise Value is -$131.4 million (2025), against an average of -$10.0 billion.
  • Peak annual rise in Enterprise Value reached 116.85% in 2021, while the deepest fall reached 50282.19% in 2021.
  • Tracing ACIU's Enterprise Value over 5 years: stood at -$125.9 billion in 2021, then surged by 99.9% to -$127.2 million in 2022, then fell by 28.41% to -$163.4 million in 2023, then declined by 15.61% to -$188.9 million in 2024, then soared by 39.47% to -$114.3 million in 2025.
  • Per Business Quant, the three latest ACIU Enterprise Value figures stand at -$114.3 million (Q4 2025), -$135.6 million (Q3 2025), and -$166.3 million (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.32 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -32.30 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -286.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -61.46 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.77 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn -7.25 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -18.44 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -8.75 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -3.01 Bn
10 AC Immune 325.88 Mn 211.53 Mn - -

Historic Data

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DateValue
Dec 31, 2025 -114.35 Mn
Sep 30, 2025 -135.60 Mn
Jun 30, 2025 -166.31 Mn
Mar 31, 2025 -161.96 Mn
Dec 31, 2024 78.06 Mn
Sep 30, 2024 79.07 Mn
Jun 30, 2024 22.68 Mn
Mar 31, 2024 -38.67 Mn
Dec 31, 2023 -163.40 Mn
Sep 30, 2023 -84.83 Mn
Jun 30, 2023 -77.39 Mn
Mar 31, 2023 -108.59 Mn
Dec 31, 2022 -127.25 Mn
Sep 30, 2022 -66.79 Mn
Jun 30, 2022 -111.32 Mn
Mar 31, 2022 -188.23 Mn
Dec 31, 2021 -125.89 Bn
Sep 30, 2021 32.57 Mn
Jun 30, 2021 32.79 Mn
Mar 31, 2021 -71.89 Bn
Dec 31, 2020 -211.16 Mn
Sep 30, 2020 -218.98 Mn
Jun 30, 2020 -194.55 Mn
Mar 31, 2020 -287.26 Mn
Dec 31, 2019 -129.92 Mn
Sep 30, 2019 -154.74 Mn
Jun 30, 2019 -205.13 Bn
Mar 31, 2019 -172.84 Mn
Dec 31, 2018 -187.36 Mn
Dec 31, 2017 -126.07 Mn
Sep 30, 2017 -158.18 Mn
Jun 30, 2017 -154.48 Mn
Mar 31, 2017 -137.53 Mn
Dec 31, 2016 -152.21 Mn
Sep 30, 2016 -156.02 Mn
Jun 30, 2016 -156.86 Mn
Dec 31, 2015 -77.33 Mn
Dec 31, 2014 -3.43 Mn