AC Immune ACIU
NASDAQ ACIU
$2.86 -0.07 (-2.39%)
At close: Sep 4, 2026 · 4:00 PM EDT

AC Immune (ACIU) Change in Cash (2016 - 2025)

AC Immune (ACIU) posted quarterly Change in Cash of -$958396.1 for Q4 2025, down 143.93% year-over-year from $2.2 million in Q4 2024, and down 102.1% quarter-over-quarter from $45.6 million in Q3 2025.

Analysis

AC Immune (ACIU) Change in Cash (2016 - 2025) Analysis & Trends

AC Immune (ACIU) has reported Change in Cash for 11 consecutive years, with -$958396.1 the latest figure, recorded in Q4 2025.

  • In Q4 2025, Change in Cash fell 143.93% year-over-year to -$958396.1; the TTM figure through Dec 2025 stood at $36.5 million (up 147.43% YoY), while the FY2025 annual figure was -$8.1 million, up 82.45% from the prior year.
  • Change in Cash fell to -$958396.1 in Q4 2025 per ACIU's latest filing, from $45.6 million in the prior quarter.
  • Across five years, Change in Cash topped out at $54.2 million in Q4 2023 and bottomed at -$51.2 million in Q2 2021.
  • Historically, Change in Cash has averaged -$6.4 million across 5 years, with a median of -$11.6 million in 2021.
  • Annual changes were most pronounced in 2021 — Change in Cash tumbled 1408.62% — and 2023, when it jumped 514.78%.
  • AC Immune's Change in Cash stood at -$11.7 million in 2021, then fell by 11.48% to -$13.1 million in 2022, then surged by 514.78% to $54.2 million in 2023, then tumbled by 95.98% to $2.2 million in 2024, then sank by 143.93% to -$958396.1 in 2025.
  • Business Quant data shows ACIU's Change in Cash at -$958396.1 in Q4 2025, $45.6 million in Q3 2025, and $9.7 million in Q2 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 649.20 Mn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn -504.60 Mn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn -
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -185.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - 374.50 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 427.25 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn -2.94 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 225.59 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -37.42 Mn
10 AC Immune 285.13 Mn 285.13 Mn - -
Historic Data

Historic Data

Download Data
DateValue
Dec 31, 2025 -958,396.06
Sep 30, 2025 45.64 Mn
Jun 30, 2025 9.71 Mn
Mar 31, 2025 -17.85 Mn
Sep 30, 2024 -49.46 Mn
Jun 30, 2024 -3.15 Mn
Mar 31, 2024 -26.61 Mn
Sep 30, 2023 -9.21 Mn
Jun 30, 2023 -19.30 Mn
Mar 31, 2023 27.96 Mn
Sep 30, 2022 -19.47 Mn
Jun 30, 2022 5.03 Mn
Mar 31, 2022 -26.64 Mn
Sep 30, 2021 -11.62 Mn
Jun 30, 2021 -51.21 Mn
Mar 31, 2021 -11.53 Mn
Sep 30, 2020 -770,233.14
Jun 30, 2020 -5.55 Mn
Mar 31, 2020 -10.62 Mn
Sep 30, 2019 6.55 Mn