AC Immune (ACIU) Change in Cash (2016 - 2025)
AC Immune (ACIU) posted quarterly Change in Cash of -$958396.1 for Q4 2025, down 143.93% year-over-year from $2.2 million in Q4 2024, and down 102.1% quarter-over-quarter from $45.6 million in Q3 2025.
Analysis
AC Immune (ACIU) Change in Cash (2016 - 2025) Analysis & Trends
AC Immune (ACIU) has reported Change in Cash for 11 consecutive years, with -$958396.1 the latest figure, recorded in Q4 2025.
- In Q4 2025, Change in Cash fell 143.93% year-over-year to -$958396.1; the TTM figure through Dec 2025 stood at $36.5 million (up 147.43% YoY), while the FY2025 annual figure was -$8.1 million, up 82.45% from the prior year.
- Change in Cash fell to -$958396.1 in Q4 2025 per ACIU's latest filing, from $45.6 million in the prior quarter.
- Across five years, Change in Cash topped out at $54.2 million in Q4 2023 and bottomed at -$51.2 million in Q2 2021.
- Historically, Change in Cash has averaged -$6.4 million across 5 years, with a median of -$11.6 million in 2021.
- Annual changes were most pronounced in 2021 — Change in Cash tumbled 1408.62% — and 2023, when it jumped 514.78%.
- AC Immune's Change in Cash stood at -$11.7 million in 2021, then fell by 11.48% to -$13.1 million in 2022, then surged by 514.78% to $54.2 million in 2023, then tumbled by 95.98% to $2.2 million in 2024, then sank by 143.93% to -$958396.1 in 2025.
- Business Quant data shows ACIU's Change in Cash at -$958396.1 in Q4 2025, $45.6 million in Q3 2025, and $9.7 million in Q2 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 649.20 Mn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | -504.60 Mn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | - |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -185.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | 374.50 Mn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 427.25 Mn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | -2.94 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 225.59 Mn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -37.42 Mn |
| 10 | AC Immune | 285.13 Mn | 285.13 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -958,396.06 |
| Sep 30, 2025 | 45.64 Mn |
| Jun 30, 2025 | 9.71 Mn |
| Mar 31, 2025 | -17.85 Mn |
| Sep 30, 2024 | -49.46 Mn |
| Jun 30, 2024 | -3.15 Mn |
| Mar 31, 2024 | -26.61 Mn |
| Sep 30, 2023 | -9.21 Mn |
| Jun 30, 2023 | -19.30 Mn |
| Mar 31, 2023 | 27.96 Mn |
| Sep 30, 2022 | -19.47 Mn |
| Jun 30, 2022 | 5.03 Mn |
| Mar 31, 2022 | -26.64 Mn |
| Sep 30, 2021 | -11.62 Mn |
| Jun 30, 2021 | -51.21 Mn |
| Mar 31, 2021 | -11.53 Mn |
| Sep 30, 2020 | -770,233.14 |
| Jun 30, 2020 | -5.55 Mn |
| Mar 31, 2020 | -10.62 Mn |
| Sep 30, 2019 | 6.55 Mn |