AC Immune (ACIU) Change in Cash (2015 - 2025)

AC Immune's (ACIU) quarterly Change in Cash came in at -$958396.1 in Q4 2025, down 143.93% year-on-year from $2.2 million in Q4 2024, and down 102.1% on a QoQ basis from $45.6 million in Q3 2025.

AC Immune (ACIU) Change in Cash (2015 - 2025) Analysis & Trends

AC Immune (ACIU) has 11 years of Change in Cash data on file, last reported at -$958396.1 in Q4 2025.

  • On a quarterly basis, Change in Cash fell 143.93% year-over-year to -$958396.1 in Q4 2025; TTM through Dec 2025 was $36.5 million, a 147.43% increase from a year earlier, with the FY2025 full-year figure at -$8.1 million, up 82.45% from the prior year.
  • Change in Cash for Q4 2025 stood at -$958396.1, down from $45.6 million in the prior quarter.
  • Over the last five years, Change in Cash for ACIU reached as high as $54.2 million in Q4 2023 and fell as low as -$51.2 million in Q2 2021.
  • Historically, Change in Cash has averaged -$6.4 million across 5 years, with a median of -$11.6 million in 2021.
  • Across the five-year window, Change in Cash sank 1408.62% in 2021 and surged 514.78% in 2023, its largest moves.
  • Year by year, Change in Cash stood at -$11.7 million in 2021, then decreased by 11.48% to -$13.1 million in 2022, then jumped by 514.78% to $54.2 million in 2023, then tumbled by 95.98% to $2.2 million in 2024, then sank by 143.93% to -$958396.1 in 2025.
  • Per Business Quant data, the three most recent Change in Cash figures were -$958396.1 in Q4 2025, $45.6 million in Q3 2025, and $9.7 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -22.03 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 243.78 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.34 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 417.10 Mn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -153.10 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - 57.19 Mn
10 AC Immune 225.68 Mn 225.68 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -958,396.06
Sep 30, 2025 45.64 Mn
Jun 30, 2025 9.71 Mn
Mar 31, 2025 -17.85 Mn
Dec 31, 2024 2.18 Mn
Sep 30, 2024 -49.46 Mn
Jun 30, 2024 -3.15 Mn
Mar 31, 2024 -26.61 Mn
Dec 31, 2023 54.24 Mn
Sep 30, 2023 -9.21 Mn
Jun 30, 2023 -19.30 Mn
Mar 31, 2023 27.96 Mn
Dec 31, 2022 -13.08 Mn
Sep 30, 2022 -19.47 Mn
Jun 30, 2022 5.03 Mn
Mar 31, 2022 -26.64 Mn
Dec 31, 2021 -11.73 Mn
Sep 30, 2021 -11.62 Mn
Jun 30, 2021 -51.21 Mn
Mar 31, 2021 -11.53 Mn