AC Immune (ACIU) Change in Cash (2015 - 2025)

AC Immune (ACIU) reported Change in Cash of -$958396.1 for Q4 2025, down 143.93% year-over-year from $2.2 million in Q4 2024, and down 102.1% quarter-over-quarter from $45.6 million in Q3 2025.

AC Immune (ACIU) Change in Cash (2015 - 2025) Analysis & Trends

AC Immune (ACIU) has 11 years of Change in Cash data on file, last reported at -$958396.1 in Q4 2025.

  • Change in Cash for Q4 2025 came in at -$958396.1, down 143.93% year-over-year; the trailing twelve-month figure through Dec 2025 was $36.5 million (up 147.43% YoY), and the FY2025 annual result was -$8.1 million, up 82.45% from the prior year.
  • Change in Cash slipped to -$958396.1 in Q4 2025 per ACIU's latest filing, from $45.6 million in the prior quarter.
  • Over five years, Change in Cash peaked at $54.2 million in Q4 2023 and troughed at -$51.2 million in Q2 2021.
  • A 5-year average of -$6.4 million and a median of -$11.6 million in 2021 frame the typical range for Change in Cash.
  • The sharpest annual moves came in 2021 and 2023: Change in Cash tumbled 1408.62% in 2021, then jumped 514.78% in 2023.
  • A 5-year view of Change in Cash shows it stood at -$11.7 million in 2021, then declined by 11.48% to -$13.1 million in 2022, then jumped by 514.78% to $54.2 million in 2023, then slumped by 95.98% to $2.2 million in 2024, then plunged by 143.93% to -$958396.1 in 2025.
  • Business Quant data shows ACIU's Change in Cash at -$958396.1 in Q4 2025, $45.6 million in Q3 2025, and $9.7 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - 2.44 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn 623.00 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -2.44 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 417.10 Mn
9 Abivax 90.15 Bn 90.15 Bn - -45.97 Mn
10 AC Immune 1.45 Bn -94.07 Bn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -958,396.06
Sep 30, 2025 45.64 Mn
Jun 30, 2025 9.71 Mn
Mar 31, 2025 -17.85 Mn
Dec 31, 2024 2.18 Mn
Sep 30, 2024 -49.46 Mn
Jun 30, 2024 -3.15 Mn
Mar 31, 2024 -26.61 Mn
Dec 31, 2023 54.24 Mn
Sep 30, 2023 -9.21 Mn
Jun 30, 2023 -19.30 Mn
Mar 31, 2023 27.96 Mn
Dec 31, 2022 -13.08 Mn
Sep 30, 2022 -19.47 Mn
Jun 30, 2022 5.03 Mn
Mar 31, 2022 -26.64 Mn
Dec 31, 2021 -11.73 Mn
Sep 30, 2021 -11.62 Mn
Jun 30, 2021 -51.21 Mn
Mar 31, 2021 -11.53 Mn