TXG vs TMO vs RGEN Stock Comparison

10x Genomics, Thermo Fisher Scientific and Repligen Prices as of Nov 4, 2026 Peers: Industry group
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TXG 10x Genomics, Inc.
$67.52 -30.9% 1M +405.4% 1Y
Market cap
$8.80B
P/E
–
Revenue (TTM)
$616.91M
Div. yield
–
Life Sciences Tools Healthcare
2 wins
RGEN Repligen Corp
$178.20 -6.0% 1M +21.3% 1Y
Market cap
$10.10B
P/E
–
Revenue (TTM)
$805.61M
Div. yield
–
Life Sciences Tools Healthcare
2 wins

Head to Head

10 decided of 12

Thermo Fisher Scientific leads on 6 of the 12 questions below (Thermo Fisher Scientific 6, Repligen 2, 10x Genomics 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionTXGTMORGENLeader
Larger companyMarket capitalisation $8.80B $261.60B $10.10B TMO
Cheaper on earningsLower P/E, profitable companies only -116.8x 37.0x -851.7x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 27.2x 91.9x TMO
Faster revenue growthRevenue growth, trailing twelve months -4.3% +8.3% +13.8% RGEN
More profitableNet margin, trailing twelve months -12.2% 14.9% -1.5% TMO
Better return on capitalReturn on invested capital — 8.0% 0.0% TMO
Less leveragedLower net debt / EBITDA — 3.1x -2.8x RGEN
Higher dividend yieldTrailing dividend yield — 0.26% — –
Better 1-year returnPrice return, last 12 months +405.4% +24.9% +21.3% TXG
Better 5-year returnAnnualised price return, 5 years -17.6%/yr +2.7%/yr -7.8%/yr TMO
Less volatileAnnualised volatility, 1 year 76.6% 30.0% 46.5% TMO
Higher overall scoreMean of the five percentile scores vs peers 62/100 59/100 56/100 TXG

Percentile Scorecard

TXGTMORGEN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisTXGTMORGEN
Valuation 45 #127 of 229 61 #90 of 229 53 #109 of 229
Growth 66 #77 of 221 39 #136 of 221 25 #167 of 221
Profitability 62 #81 of 209 81 #40 of 209 66 #71 of 209
Financial Health 69 #75 of 240 31 #166 of 240 82 #45 of 240
Shareholder Returns 70 #45 of 146 82 #27 of 146 55 #67 of 146
Overall 62 59 56
  • TXG ranked among 248 companies in Medical Devices and Diagnostics
  • TMO ranked among 248 companies in Medical Devices and Diagnostics
  • RGEN ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodTXGTMORGENSPY
1 month -30.9%+4.4%-6.0% -1.0%
3 months +42.3%+22.3%+12.4% -0.4%
6 months +196.9%+49.3%+41.7% +4.5%
Year to date +314.0%+21.8%+8.8% +12.4%
1 year +405.4%+24.9%+21.3% +13.6%
3 years +70.0%+55.3%+18.5% +76.4%
3 years, per year +19.4%+15.8%+5.8% +20.8%
5 years -62.1%+14.5%-33.2% +63.7%
5 years, per year -17.6%+2.7%-7.8% +10.4%
10 years —+381.7%+558.3% +267.7%
10 years, per year —+17.0%+20.7% +13.9%

Risk

MeasureTXGTMORGENSPY
Volatility, 1Y 76.6%30.0%46.5% 12.8%
Downside volatility, 1Y 72.4%28.6%46.8% 12.7%
Beta vs S&P 500, 1Y 2.390.641.23 1.00
Return / volatility, 1Y 5.290.830.46 1.06
Max drawdown, 5Y -96.0%-41.5%-64.7% -25.4%
From 52-week high -30.9%-0.5%-8.4% -1.6%
52-week high $97.74$709.29$194.57 $779.14
52-week low $13.00$438.34$102.87 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleTXGTMORGEN
P/E now vs peer median -116.8xmedian 28.5x 37.0xmedian 28.5x -851.7xmedian 28.5x
P/S now vs peer median 14.3xmedian 2.9x 5.5xmedian 2.9x 12.5xmedian 2.9x
EV/EBITDA now vs peer median -197.0xmedian 18.5x 25.7xmedian 18.5x 89.3xmedian 18.5x
P/FCF now vs peer median 72.4xmedian 26.7x 34.4xmedian 26.7x 94.7xmedian 26.7x
P/B now vs peer median 10.7xmedian 2.3x 4.8xmedian 2.3x 4.8xmedian 2.3x
PEG now vs peer median -4.35median 0.93 4.89median 0.93 29.96median 0.93

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsTXGTMORGEN
Revenue $616.91M $47.35B $805.61M
Gross profit $432.03M $19.45B $430.67M
Operating income -$88.38M $8.47B $18.24M
Net income -$75.13M $7.09B -$11.80M
Free cash flow $121.44M $7.60B $106.72M
R&D $226.80M $1.40B $57.23M
EPS (diluted) $-0.58 $19.06 $-0.21
Cash & equivalents – $5.46B $726.96M
Total debt – $41.37B $555.60M
Shares (diluted) 129.98M 371.00M 56.64M
Enterprise value $8.60B $238.24B $6.88B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricTXGTMORGEN
P/E -116.8x 37.0x -851.7x
P/FCF 72.4x 34.4x 94.7x
P/Operating cash flow 69.2x 28.1x 77.8x
P/S 14.3x 5.5x 12.5x
P/B 10.7x 4.8x 4.8x
P/Tangible book 11.5x 7.1x 5.7x
EV/EBITDA -197.0x 25.7x 89.3x
EV/EBIT -99.0x 35.1x 537.1x
EV/Revenue 14.2x 6.3x 12.2x
EV/FCF 72.0x 39.1x 91.8x
EV/Operating cash flow 68.8x 31.8x 75.4x
PEG (3Y EPS CAGR) -4.35 4.89 29.96

Growth

14 metrics
MetricTXGTMORGEN
Revenue growth (1Y) -4.3% 8.3% 13.8%
Revenue CAGR (3Y) 2.8% 2.9% 7.3%
Gross profit growth (1Y) -3.5% 7.8% 33.0%
Gross profit CAGR (3Y) 1.1% 4.0% 13.3%
Operating income growth (1Y) 12.1% 12.8% 2,185%
Operating income CAGR (3Y) 20.9% 7.2% -40.5%
Net income growth (1Y) 11.2% 7.9% -779.2%
Net income CAGR (3Y) 24.2% 6.2% -28.4%
EPS growth (1Y) 14.9% 9.7% -777.9%
EPS CAGR (3Y) 26.8% 7.6% -28.4%
Operating cash flow growth (1Y) 89.8% 21.9% -0.8%
Operating cash flow CAGR (3Y) 135.5% 4.5% -4.0%
Free cash flow growth (1Y) 113.5% 24.3% -3.0%
Free cash flow CAGR (3Y) 44.7% 5.1% 1.8%

Profitability

14 metrics
MetricTXGTMORGEN
Gross margin 70.0% 41.1% 53.5%
EBITDA margin -7.2% 24.4% 13.6%
Operating margin -14.3% 17.9% 2.3%
Pretax margin -12.1% 16.7% 1.0%
Net margin -12.2% 14.9% -1.5%
FCF margin 19.7% 16.0% 13.2%
Operating cash flow margin 20.6% 19.7% 16.1%
Return on equity -9.2% 13.2% -0.6%
Return on assets -7.3% 6.2% -0.4%
Return on invested capital – 8.0% 0.0%
Return on capital employed -9.8% 8.5% 0.6%
Asset turnover 0.6x 0.4x 0.3x
Cash conversion (OCF / net income) -1.7x 1.3x -11.0x
Stock comp / revenue 16.0% 0.7% 4.2%

Financial Health

11 metrics
MetricTXGTMORGEN
Debt / assets – 36.2% 19.0%
Debt / equity – 0.8x 0.3x
Net debt / EBITDA – 3.1x -2.8x
Debt / FCF – 5.4x 5.2x
Liabilities / assets 19.9% 52.1% 28.5%
Equity / assets 80.1% 47.9% 71.5%
Interest coverage – 5.5x 0.8x
Current ratio 5.7x 1.8x 9.9x
Quick ratio 0.8x 1.2x 8.1x
Cash ratio 0.4x 0.4x 6.9x
Altman Z-score 24.67 4.20 8.22

Shareholder Returns

7 metrics
MetricTXGTMORGEN
Dividend yield – 0.3% –
Net buyback yield -0.1% 1.5% -0.2%
Shareholder yield -0.1% 1.8% -0.2%
Payout ratio (earnings) – 9.5% –
Payout ratio (FCF) – 8.9% –
Dividend growth (1Y) – 8.0% –
Dividend CAGR (3Y) – 10.1% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusTXGTMORGEN
Forward P/E – 27.2xFY2026 91.9xFY2026
EPS, next fiscal year $-0.79FY2026 $25.91FY2026 $1.94FY2026
EPS growth, next FY – +13.3%FY2026 +13.5%FY2026
EPS growth, the year after – +2.0% +29.4%
Revenue, next fiscal year $580.42MFY2026 $50.12BFY2026 $773.94MFY2026
Revenue growth, next FY -9.7%FY2026 +12.5%FY2026 +4.8%FY2026
Revenue growth, the year after +24.6% -2.8% +35.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersTXGTMORGEN
Held by institutions 98.4% 90.2% 100.0%
Institutions holding 391 2,627 483
Change in shares held, QoQ +2.4% +0.8% +1.2%
Institutions buying 198 1,145 273
Institutions selling 137 1,145 141
Buyers to sellers 1.45 1.00 1.94

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

TXGTMORGEN
TXG 1.00 0.50 0.49
TMO 0.50 1.00 0.67
RGEN 0.49 0.67 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, TXG, TMO and RGEN?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: 10x Genomics (TXG) $8.80B, Thermo Fisher Scientific (TMO) $261.60B, Repligen (RGEN) $10.10B.

Which company is growing faster?

Repligen (RGEN) grew revenue fastest over the trailing twelve months: 10x Genomics (TXG) -4.3%, Thermo Fisher Scientific (TMO) +8.3%, Repligen (RGEN) +13.8%.

Which company is more profitable?

Thermo Fisher Scientific (TMO) has the highest net margin (10x Genomics (TXG) -12.2%, Thermo Fisher Scientific (TMO) 14.9%, Repligen (RGEN) -1.5%). On return on invested capital, Thermo Fisher Scientific (TMO) leads (Thermo Fisher Scientific (TMO) 8.0%, Repligen (RGEN) 0.0%).

Which stock has performed better?

Over the past year 10x Genomics (TXG) returned the most: 10x Genomics (TXG) +405.4%, Thermo Fisher Scientific (TMO) +24.9%, Repligen (RGEN) +21.3%. Over five years, Thermo Fisher Scientific (TMO) compounded fastest (10x Genomics (TXG) -17.6%/yr, Thermo Fisher Scientific (TMO) +2.7%/yr, Repligen (RGEN) -7.8%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Thermo Fisher Scientific (TMO) 0.26%. 10x Genomics (TXG) and Repligen (RGEN) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Thermo Fisher Scientific (TMO) has been the steadiest (10x Genomics (TXG) 76.6%, Thermo Fisher Scientific (TMO) 30.0%, Repligen (RGEN) 46.5%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, TXG, TMO and RGEN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Thermo Fisher Scientific (TMO) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.