TXG vs TMO vs QGEN Stock Comparison

10x Genomics, Thermo Fisher Scientific and Qiagen Prices as of Oct 29, 2026 Peers: Industry group
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TXG 10x Genomics, Inc.
$81.55 -9.4% 1M +532.2% 1Y
Market cap
$9.00B
P/E
–
Revenue (TTM)
$616.91M
Div. yield
–
Life Sciences Tools Healthcare
1 win
QGEN Qiagen N.V.
$50.38 +13.5% 1M +1.4% 1Y
Market cap
$10.93B
P/E
26.7x
Revenue (TTM)
$2.10B
Div. yield
–
Life Sciences Tools Healthcare
4 wins

Head to Head

9 decided of 12

Thermo Fisher Scientific leads on 4 of the 12 questions below (Thermo Fisher Scientific 4, Qiagen 4, 10x Genomics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionTXGTMOQGENLeader
Larger companyMarket capitalisation $9.00B $258.05B $10.93B TMO
Cheaper on earningsLower P/E, profitable companies only -119.8x 36.5x 26.7x QGEN
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 27.4x 21.4x QGEN
Faster revenue growthRevenue growth, trailing twelve months -4.3% +8.3% +3.0% TMO
More profitableNet margin, trailing twelve months -12.2% — 19.5% QGEN
Better return on capitalReturn on invested capital — — 7.9% –
Less leveragedLower net debt / EBITDA — — 1.3x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +532.2% +27.0% +1.4% TXG
Better 5-year returnAnnualised price return, 5 years -12.8%/yr +2.3%/yr -4.1%/yr TMO
Less volatileAnnualised volatility, 1 year 74.1% 29.8% 35.7% TMO
Higher overall scoreMean of the five percentile scores vs peers 62/100 51/100 71/100 QGEN

Percentile Scorecard

TXGTMOQGEN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisTXGTMOQGEN
Valuation 46 #124 of 227 50 #113 of 227 77 #54 of 227
Growth 66 #75 of 218 41 #130 of 218 31 #151 of 218
Profitability 61 #79 of 202 70 #61 of 202 93 #16 of 202
Financial Health 67 #77 of 233 – 63 #87 of 233
Shareholder Returns 68 #42 of 130 44 #73 of 130 93 #10 of 130
Overall 62 51 71
  • TXG ranked among 247 companies in Medical Devices and Diagnostics
  • TMO ranked among 247 companies in Medical Devices and Diagnostics
  • QGEN ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodTXGTMOQGENSPY
1 month -9.4%+4.4%+13.5% +0.7%
3 months +65.0%+23.0%+21.5% +3.7%
6 months +269.8%+48.1%+45.7% +7.1%
Year to date +400.0%+22.4%+6.4% +12.8%
1 year +532.2%+27.0%+1.4% +11.9%
3 years +128.1%+63.4%+27.0% +85.2%
3 years, per year +31.7%+17.8%+8.3% +22.8%
5 years -49.4%+12.0%-19.1% +67.6%
5 years, per year -12.8%+2.3%-4.1% +10.9%
10 years —+381.8%+75.8% +262.0%
10 years, per year —+17.0%+5.8% +13.7%

Risk

MeasureTXGTMOQGENSPY
Volatility, 1Y 74.1%29.8%35.7% 12.7%
Downside volatility, 1Y 66.2%28.4%30.5% 12.6%
Beta vs S&P 500, 1Y 2.250.620.47 1.00
Return / volatility, 1Y 7.180.910.04 0.94
Max drawdown, 5Y -96.1%-41.5%-48.2% -25.4%
From 52-week high -16.6%0.0%-9.5% -1.2%
52-week high $97.74$709.29$55.66 $779.14
52-week low $12.44$438.34$32.63 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleTXGTMOQGEN
P/E now vs peer median -141.1xmedian 28.7x 37.2xmedian 28.7x 26.7xmedian 28.7x
P/S now vs peer median 17.2xmedian 3.0x 5.5xmedian 3.0x 5.2xmedian 3.0x
EV/EBITDA now vs peer median -238.1xmedian 17.8x —median 17.8x 18.1xmedian 17.8x
P/FCF now vs peer median 87.5xmedian 26.4x 34.0xmedian 26.4x 11.0xmedian 26.4x
P/B now vs peer median 12.9xmedian 2.4x 4.8xmedian 2.4x 3.3xmedian 2.4x
PEG now vs peer median -5.26median 0.99 4.91median 0.99 3.62median 0.99

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsTXGTMOQGEN
Revenue $616.91M $47.35B $2.10B
Gross profit $432.03M – $1.31B
Operating income -$88.38M $8.47B $445.43M
Net income -$75.13M $7.09B $409.32M
Free cash flow $121.44M – $991.33M
R&D $226.80M $1.40B $194.67M
EPS (diluted) $-0.58 $19.06 $1.87
Cash & equivalents – $5.46B $768.50M
Total debt – – $6.86B
Shares (diluted) 129.98M 371.00M 218.88M
Enterprise value $8.80B $258.05B $6.70B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricTXGTMOQGEN
P/E -141.1x 37.2x 26.7x
P/FCF 87.5x 34.0x 11.0x
P/Operating cash flow 83.6x 28.1x 16.7x
P/S 17.2x 5.5x 5.2x
P/B 12.9x 4.8x 3.3x
P/Tangible book 13.9x 7.1x 3.6x
EV/EBITDA -238.1x – 18.1x
EV/EBIT -119.6x – 26.4x
EV/Revenue 17.1x 5.5x 5.6x
EV/FCF 87.1x – 11.9x
EV/Operating cash flow 83.2x 28.1x 18.0x
PEG (3Y EPS CAGR) -5.26 4.91 3.62

Growth

14 metrics
MetricTXGTMOQGEN
Revenue growth (1Y) -4.3% 8.3% 3.0%
Revenue CAGR (3Y) 2.8% 2.9% 2.0%
Gross profit growth (1Y) -3.5% – 1.7%
Gross profit CAGR (3Y) 1.1% – 1.3%
Operating income growth (1Y) 12.1% 12.8% -4.9%
Operating income CAGR (3Y) 20.9% 7.2% 3.3%
Net income growth (1Y) 11.2% 7.9% 143.9%
Net income CAGR (3Y) 24.2% 6.2% 6.7%
EPS growth (1Y) 14.9% 9.7% 12.5%
EPS CAGR (3Y) 26.8% 7.6% 7.4%
Operating cash flow growth (1Y) 89.8% 21.9% -3.0%
Operating cash flow CAGR (3Y) 135.5% 4.5% 8.0%
Free cash flow growth (1Y) 113.5% – 2.3%
Free cash flow CAGR (3Y) 44.7% – 10.5%

Profitability

14 metrics
MetricTXGTMOQGEN
Gross margin 70.0% – 62.2%
EBITDA margin -7.2% – 31.0%
Operating margin -14.3% – 21.2%
Pretax margin -12.1% – 22.0%
Net margin -12.2% – 19.5%
FCF margin 19.7% – 47.2%
Operating cash flow margin 20.6% 19.7% 31.2%
Return on equity -9.2% 13.2% 12.2%
Return on assets -7.3% 6.2% 7.0%
Return on invested capital – – 7.9%
Return on capital employed -9.8% – 8.5%
Asset turnover 0.6x 0.4x 0.4x
Cash conversion (OCF / net income) -1.7x 1.3x 1.6x
Stock comp / revenue 16.0% – 2.1%

Financial Health

11 metrics
MetricTXGTMOQGEN
Debt / assets – – 27.9%
Debt / equity – – 0.5x
Net debt / EBITDA – – 1.3x
Debt / FCF – – 1.7x
Liabilities / assets 19.9% – 43.0%
Equity / assets 80.1% 47.9% 57.0%
Interest coverage – – 11.3x
Current ratio 5.7x 1.8x 2.8x
Quick ratio 0.8x – 2.0x
Cash ratio 0.4x – 1.4x
Altman Z-score 30.04 – 4.08

Shareholder Returns

7 metrics
MetricTXGTMOQGEN
Dividend yield – 0.3% 5.2%
Net buyback yield -0.1% – 0.6%
Shareholder yield -0.1% 0.3% 5.8%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusTXGTMOQGEN
Forward P/E – 27.4xFY2026 21.4xFY2026
EPS, next fiscal year $-0.79FY2026 $25.91FY2026 $2.35FY2026
EPS growth, next FY – +13.3%FY2026 -1.3%FY2026
EPS growth, the year after – +2.0% +17.4%
Revenue, next fiscal year $580.42MFY2026 $50.12BFY2026 $2.25BFY2026
Revenue growth, next FY -9.7%FY2026 +12.5%FY2026 +7.8%FY2026
Revenue growth, the year after +24.6% -2.8% -2.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersTXGTMOQGEN
Held by institutions 100.0% 90.2% 67.3%
Institutions holding 390 2,624 338
Change in shares held, QoQ +2.4% +0.8% +16.5%
Institutions buying 197 1,144 216
Institutions selling 137 1,144 86
Buyers to sellers 1.44 1.00 2.51

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

TXGTMOQGEN
TXG 1.00 0.50 0.45
TMO 0.50 1.00 0.45
QGEN 0.45 0.45 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, TXG, TMO and QGEN?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: 10x Genomics (TXG) $9.00B, Thermo Fisher Scientific (TMO) $258.05B, Qiagen (QGEN) $10.93B.

Which stock is cheaper, TXG, TMO and QGEN?

Qiagen (QGEN) trades on the lowest price-to-earnings ratio (10x Genomics (TXG) -119.8x, Thermo Fisher Scientific (TMO) 36.5x, Qiagen (QGEN) 26.7x). On next year's consensus earnings, Qiagen (QGEN) is cheapest (Thermo Fisher Scientific (TMO) 27.4x, Qiagen (QGEN) 21.4x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Thermo Fisher Scientific (TMO) grew revenue fastest over the trailing twelve months: 10x Genomics (TXG) -4.3%, Thermo Fisher Scientific (TMO) +8.3%, Qiagen (QGEN) +3.0%.

Which company is more profitable?

Qiagen (QGEN) has the highest net margin (10x Genomics (TXG) -12.2%, Qiagen (QGEN) 19.5%).

Which stock has performed better?

Over the past year 10x Genomics (TXG) returned the most: 10x Genomics (TXG) +532.2%, Thermo Fisher Scientific (TMO) +27.0%, Qiagen (QGEN) +1.4%. Over five years, Thermo Fisher Scientific (TMO) compounded fastest (10x Genomics (TXG) -12.8%/yr, Thermo Fisher Scientific (TMO) +2.3%/yr, Qiagen (QGEN) -4.1%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Thermo Fisher Scientific (TMO) has been the steadiest (10x Genomics (TXG) 74.1%, Thermo Fisher Scientific (TMO) 29.8%, Qiagen (QGEN) 35.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, TXG, TMO and QGEN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Thermo Fisher Scientific (TMO) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.