TXG vs TMO vs ILMN Stock Comparison

10x Genomics, Thermo Fisher Scientific and Illumina Prices as of Oct 28, 2026 Peers: Industry group
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TXG 10x Genomics, Inc.
$83.62 -5.5% 1M +526.8% 1Y
Market cap
$10.89B
P/E
–
Revenue (TTM)
$616.91M
Div. yield
–
Life Sciences Tools Healthcare
1 win
ILMN Illumina, Inc.
$288.79 +6.2% 1M +195.3% 1Y
Market cap
$43.61B
P/E
52.9x
Revenue (TTM)
$4.49B
Div. yield
–
Life Sciences Tools Healthcare
2 wins

Head to Head

9 decided of 12

Thermo Fisher Scientific leads on 6 of the 12 questions below (Thermo Fisher Scientific 6, Illumina 2, 10x Genomics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionTXGTMOILMNLeader
Larger companyMarket capitalisation $10.89B $260.59B $43.61B TMO
Cheaper on earningsLower P/E, profitable companies only -144.7x 37.0x 52.9x TMO
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 27.2x 57.9x TMO
Faster revenue growthRevenue growth, trailing twelve months -4.3% +8.3% +4.9% TMO
More profitableNet margin, trailing twelve months -12.2% — 18.4% ILMN
Better return on capitalReturn on invested capital — — 15.1% –
Less leveragedLower net debt / EBITDA — — 0.7x –
Higher dividend yieldTrailing dividend yield — 0.26% — –
Better 1-year returnPrice return, last 12 months +526.8% +26.4% +195.3% TXG
Better 5-year returnAnnualised price return, 5 years -12.3%/yr +2.2%/yr -6.5%/yr TMO
Less volatileAnnualised volatility, 1 year 74.2% 29.8% 50.4% TMO
Higher overall scoreMean of the five percentile scores vs peers 61/100 51/100 65/100 ILMN

Percentile Scorecard

TXGTMOILMN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisTXGTMOILMN
Valuation 44 #128 of 227 49 #116 of 227 50 #115 of 227
Growth 66 #76 of 219 40 #132 of 219 46 #119 of 219
Profitability 62 #78 of 205 71 #61 of 205 97 #8 of 205
Financial Health 68 #77 of 237 – 51 #116 of 237
Shareholder Returns 68 #44 of 135 44 #76 of 135 83 #24 of 135
Overall 61 51 65
  • TXG ranked among 247 companies in Medical Devices and Diagnostics
  • TMO ranked among 247 companies in Medical Devices and Diagnostics
  • ILMN ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodTXGTMOILMNSPY
1 month -5.5%+3.9%+6.2% +0.9%
3 months +80.5%+22.3%+48.2% +5.9%
6 months +314.0%+51.2%+139.9% +8.5%
Year to date +412.7%+21.6%+120.2% +13.3%
1 year +526.8%+26.4%+195.3% +12.4%
3 years +129.7%+63.4%+171.8% +88.1%
3 years, per year +32.0%+17.8%+39.6% +23.5%
5 years -48.1%+11.3%-28.5% +68.2%
5 years, per year -12.3%+2.2%-6.5% +11.0%
10 years —+378.8%+114.2% +263.4%
10 years, per year —+17.0%+7.9% +13.8%

Risk

MeasureTXGTMOILMNSPY
Volatility, 1Y 74.2%29.8%50.4% 12.7%
Downside volatility, 1Y 66.3%28.4%39.0% 12.7%
Beta vs S&P 500, 1Y 2.240.620.83 1.00
Return / volatility, 1Y 7.100.883.88 0.98
Max drawdown, 5Y -96.1%-41.5%-82.9% -25.4%
From 52-week high -14.4%0.0%-1.7% -0.9%
52-week high $97.74$704.77$293.69 $779.14
52-week low $12.44$438.34$95.03 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleTXGTMOILMN
P/E now vs peer median -144.7xmedian 28.8x 37.0xmedian 28.8x 52.9xmedian 28.8x
P/S now vs peer median 17.7xmedian 3.0x 5.5xmedian 3.0x 9.7xmedian 3.0x
EV/EBITDA now vs peer median -244.2xmedian 17.4x —median 17.4x 38.5xmedian 17.4x
P/FCF now vs peer median 89.7xmedian 25.7x 34.0xmedian 25.7x 46.8xmedian 25.7x
P/B now vs peer median 13.2xmedian 2.4x 4.8xmedian 2.4x 15.4xmedian 2.4x
PEG now vs peer median -5.39median 1.03 4.88median 1.03 1.75median 1.03

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsTXGTMOILMN
Revenue $616.91M $47.35B $4.49B
Gross profit $432.03M – $2.98B
Operating income -$88.38M $8.47B $882.00M
Net income -$75.13M $7.09B $825.00M
Free cash flow $121.44M – $931.00M
R&D $226.80M $1.40B $960.00M
EPS (diluted) $-0.58 $19.06 $5.39
Cash & equivalents – $5.46B $1.04B
Total debt – – $1.99B
Shares (diluted) 129.98M 371.00M 153.00M
Enterprise value $10.70B $260.71B $38.37B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricTXGTMOILMN
P/E -144.7x 37.0x 52.9x
P/FCF 89.7x 34.0x 46.8x
P/Operating cash flow 85.7x 27.9x 39.8x
P/S 17.7x 5.5x 9.7x
P/B 13.2x 4.8x 15.4x
P/Tangible book 14.3x 7.1x 18.0x
EV/EBITDA -244.2x – 38.5x
EV/EBIT -122.7x – 50.4x
EV/Revenue 17.6x 5.5x 9.9x
EV/FCF 89.3x – 47.7x
EV/Operating cash flow 85.3x 27.9x 40.6x
PEG (3Y EPS CAGR) -5.39 4.88 1.75

Growth

14 metrics
MetricTXGTMOILMN
Revenue growth (1Y) -4.3% 8.3% 4.9%
Revenue CAGR (3Y) 2.8% 2.9% -1.0%
Gross profit growth (1Y) -3.5% – 4.6%
Gross profit CAGR (3Y) 1.1% – 2.9%
Operating income growth (1Y) 12.1% 12.8% -31.8%
Operating income CAGR (3Y) 20.9% 7.2% 28.3%
Net income growth (1Y) 11.2% 7.9% -34.4%
Net income CAGR (3Y) 24.2% 6.2% 30.0%
EPS growth (1Y) 14.9% 9.7% -32.7%
EPS CAGR (3Y) 26.8% 7.6% 30.1%
Operating cash flow growth (1Y) 89.8% 21.9% -5.1%
Operating cash flow CAGR (3Y) 135.5% 4.5% 38.1%
Free cash flow growth (1Y) 113.5% – -9.7%
Free cash flow CAGR (3Y) 44.7% – 105.0%

Profitability

14 metrics
MetricTXGTMOILMN
Gross margin 70.0% – 66.4%
EBITDA margin -7.2% – 25.7%
Operating margin -14.3% – 19.6%
Pretax margin -12.1% – 22.6%
Net margin -12.2% – 18.4%
FCF margin 19.7% – 20.7%
Operating cash flow margin 20.6% 19.7% 24.4%
Return on equity -9.2% 13.2% 29.9%
Return on assets -7.3% 6.2% 12.5%
Return on invested capital – – 15.1%
Return on capital employed -9.8% – 17.5%
Asset turnover 0.6x 0.4x 0.7x
Cash conversion (OCF / net income) -1.7x 1.3x 1.3x
Stock comp / revenue 16.0% – 5.9%

Financial Health

11 metrics
MetricTXGTMOILMN
Debt / assets – – 29.9%
Debt / equity – – 0.7x
Net debt / EBITDA – – 0.7x
Debt / FCF – – 2.1x
Liabilities / assets 19.9% – 57.3%
Equity / assets 80.1% 47.9% 42.7%
Interest coverage – – 8.9x
Current ratio 5.7x 1.8x 1.8x
Quick ratio 0.8x – 1.2x
Cash ratio 0.4x – 0.7x
Altman Z-score 30.83 – 8.19

Shareholder Returns

7 metrics
MetricTXGTMOILMN
Dividend yield – 0.3% –
Net buyback yield -0.1% – 1.2%
Shareholder yield -0.1% 0.3% 1.2%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusTXGTMOILMN
Forward P/E – 27.2xFY2026 57.9xFY2026
EPS, next fiscal year $-0.79FY2026 $25.91FY2026 $4.99FY2026
EPS growth, next FY – +13.3%FY2026 +3.1%FY2026
EPS growth, the year after – +2.0% +25.7%
Revenue, next fiscal year $580.42MFY2026 $50.12BFY2026 $4.52BFY2026
Revenue growth, next FY -9.7%FY2026 +12.5%FY2026 +4.1%FY2026
Revenue growth, the year after +24.6% -2.8% +12.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersTXGTMOILMN
Held by institutions 100.0% 90.2% 100.0%
Institutions holding 389 2,623 933
Change in shares held, QoQ +2.4% +0.8% +0.0%
Institutions buying 197 1,143 463
Institutions selling 137 1,144 330
Buyers to sellers 1.44 1.00 1.40

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

TXGTMOILMN
TXG 1.00 0.50 0.51
TMO 0.50 1.00 0.50
ILMN 0.51 0.50 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, TXG, TMO and ILMN?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: 10x Genomics (TXG) $10.89B, Thermo Fisher Scientific (TMO) $260.59B, Illumina (ILMN) $43.61B.

Which stock is cheaper, TXG, TMO and ILMN?

Thermo Fisher Scientific (TMO) trades on the lowest price-to-earnings ratio (10x Genomics (TXG) -144.7x, Thermo Fisher Scientific (TMO) 37.0x, Illumina (ILMN) 52.9x). On next year's consensus earnings, Thermo Fisher Scientific (TMO) is cheapest (Thermo Fisher Scientific (TMO) 27.2x, Illumina (ILMN) 57.9x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Thermo Fisher Scientific (TMO) grew revenue fastest over the trailing twelve months: 10x Genomics (TXG) -4.3%, Thermo Fisher Scientific (TMO) +8.3%, Illumina (ILMN) +4.9%.

Which company is more profitable?

Illumina (ILMN) has the highest net margin (10x Genomics (TXG) -12.2%, Illumina (ILMN) 18.4%).

Which stock has performed better?

Over the past year 10x Genomics (TXG) returned the most: 10x Genomics (TXG) +526.8%, Thermo Fisher Scientific (TMO) +26.4%, Illumina (ILMN) +195.3%. Over five years, Thermo Fisher Scientific (TMO) compounded fastest (10x Genomics (TXG) -12.3%/yr, Thermo Fisher Scientific (TMO) +2.2%/yr, Illumina (ILMN) -6.5%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Thermo Fisher Scientific (TMO) 0.26%. 10x Genomics (TXG) and Illumina (ILMN) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Thermo Fisher Scientific (TMO) has been the steadiest (10x Genomics (TXG) 74.2%, Thermo Fisher Scientific (TMO) 29.8%, Illumina (ILMN) 50.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, TXG, TMO and ILMN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Thermo Fisher Scientific (TMO) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.