TMO vs TXG vs BIO Stock Comparison

Thermo Fisher Scientific, 10x Genomics and Bio-Rad Laboratories Prices as of Oct 27, 2026 Peers: Industry group
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TXG 10x Genomics, Inc.
$78.02 -9.0% 1M +474.1% 1Y
Market cap
$10.16B
P/E
–
Revenue (TTM)
$616.91M
Div. yield
–
Life Sciences Tools Healthcare
1 win

Head to Head

9 decided of 12

Thermo Fisher Scientific leads on 6 of the 12 questions below (Thermo Fisher Scientific 6, Bio-Rad Laboratories 2, 10x Genomics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionTMOTXGBIOLeader
Larger companyMarket capitalisation $256.36B $10.16B $10.19B TMO
Cheaper on earningsLower P/E, profitable companies only 36.4x -135.0x 45.8x TMO
Cheaper on forward earningsLower price / next fiscal year consensus EPS 26.8x — 38.3x TMO
Faster revenue growthRevenue growth, trailing twelve months +8.3% -4.3% +1.4% TMO
More profitableNet margin, trailing twelve months — -12.2% 8.6% BIO
Better return on capitalReturn on invested capital — — 0.4% –
Less leveragedLower net debt / EBITDA — — — –
Higher dividend yieldTrailing dividend yield 0.27% — — –
Better 1-year returnPrice return, last 12 months +23.0% +474.1% +13.3% TXG
Better 5-year returnAnnualised price return, 5 years +2.3%/yr -13.9%/yr -13.6%/yr TMO
Less volatileAnnualised volatility, 1 year 29.8% 73.9% 37.0% TMO
Higher overall scoreMean of the five percentile scores vs peers 51/100 61/100 63/100 BIO

Percentile Scorecard

TMOTXGBIO

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisTMOTXGBIO
Valuation 50 #113 of 227 43 #130 of 227 78 #51 of 227
Growth 41 #130 of 219 66 #76 of 219 20 #176 of 219
Profitability 70 #63 of 206 63 #77 of 206 71 #61 of 206
Financial Health – 68 #78 of 238 68 #77 of 238
Shareholder Returns 44 #76 of 134 68 #44 of 134 80 #28 of 134
Overall 51 61 63
  • TMO ranked among 247 companies in Medical Devices and Diagnostics
  • TXG ranked among 247 companies in Medical Devices and Diagnostics
  • BIO ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodTMOTXGBIOSPY
1 month +2.9%-9.0%+0.0% -0.2%
3 months +20.3%+65.8%+15.2% +3.9%
6 months +47.4%+265.1%+36.4% +8.2%
Year to date +19.7%+378.4%+25.7% +12.9%
1 year +23.0%+474.1%+13.3% +12.3%
3 years +60.7%+114.3%+40.7% +87.4%
3 years, per year +17.1%+28.9%+12.1% +23.3%
5 years +11.8%-52.6%-51.7% +67.9%
5 years, per year +2.3%-13.9%-13.6% +10.9%
10 years +364.6%—+141.8% +261.1%
10 years, per year +16.6%—+9.2% +13.7%

Risk

MeasureTMOTXGBIOSPY
Volatility, 1Y 29.8%73.9%37.0% 12.7%
Downside volatility, 1Y 28.3%66.1%35.8% 12.7%
Beta vs S&P 500, 1Y 0.622.220.76 1.00
Return / volatility, 1Y 0.776.410.36 0.97
Max drawdown, 5Y -41.5%-96.1%-72.7% -25.4%
From 52-week high -0.5%-20.2%-2.4% -1.2%
52-week high $696.55$97.74$390.34 $779.14
52-week low $438.34$12.44$241.71 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleTMOTXGBIO
P/E now vs peer median 36.4xmedian 29.6x -135.0xmedian 29.6x 45.8xmedian 29.6x
P/S now vs peer median 5.4xmedian 2.9x 16.5xmedian 2.9x 3.9xmedian 2.9x
EV/EBITDA now vs peer median —median 17.4x -227.8xmedian 17.4x —median 17.4x
P/FCF now vs peer median 34.0xmedian 22.3x 83.7xmedian 22.3x 28.8xmedian 22.3x
P/B now vs peer median 4.7xmedian 2.3x 12.3xmedian 2.3x 1.4xmedian 2.3x
PEG now vs peer median 4.80median 1.04 -5.03median 1.04 1.24median 1.04

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsTMOTXGBIO
Revenue $47.35B $616.91M $2.59B
Gross profit – $432.03M $1.34B
Operating income $8.47B -$88.38M $53.10M
Net income $7.09B -$75.13M $222.40M
Free cash flow – $121.44M $353.10M
R&D $1.40B $226.80M $265.70M
EPS (diluted) $19.06 $-0.58 $8.29
Cash & equivalents $5.46B – $517.00M
Total debt – – $1.20B
Shares (diluted) 371.00M 129.98M 26.81M
Enterprise value $256.48B $9.97B $4.04B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricTMOTXGBIO
P/E 36.4x -135.0x 45.8x
P/FCF 34.0x 83.7x 28.8x
P/Operating cash flow 27.5x 80.0x 20.7x
P/S 5.4x 16.5x 3.9x
P/B 4.7x 12.3x 1.4x
P/Tangible book 7.0x 13.3x 1.5x
EV/EBITDA – -227.8x –
EV/EBIT – -114.4x 184.0x
EV/Revenue 5.4x 16.4x 3.8x
EV/FCF – 83.3x 27.7x
EV/Operating cash flow 27.5x 79.6x 19.8x
PEG (3Y EPS CAGR) 4.80 -5.03 1.24

Growth

14 metrics
MetricTMOTXGBIO
Revenue growth (1Y) 8.3% -4.3% 1.4%
Revenue CAGR (3Y) 2.9% 2.8% -2.2%
Gross profit growth (1Y) – -3.5% -0.4%
Gross profit CAGR (3Y) – 1.1% -3.5%
Operating income growth (1Y) 12.8% 12.1% -76.3%
Operating income CAGR (3Y) 7.2% 20.9% -47.4%
Net income growth (1Y) 7.9% 11.2% -30.3%
Net income CAGR (3Y) 6.2% 24.2% 36.1%
EPS growth (1Y) 9.7% 14.9% -29.3%
EPS CAGR (3Y) 7.6% 26.8% 36.9%
Operating cash flow growth (1Y) 21.9% 89.8% -7.8%
Operating cash flow CAGR (3Y) 4.5% 135.5% 19.8%
Free cash flow growth (1Y) – 113.5% -4.8%
Free cash flow CAGR (3Y) – 44.7% 31.9%

Profitability

14 metrics
MetricTMOTXGBIO
Gross margin – 70.0% 51.9%
EBITDA margin – -7.2% –
Operating margin – -14.3% 2.1%
Pretax margin – -12.1% 13.5%
Net margin – -12.2% 8.6%
FCF margin – 19.7% 13.6%
Operating cash flow margin 19.7% 20.6% 19.0%
Return on equity 13.2% -9.2% 3.2%
Return on assets 6.2% -7.3% 2.2%
Return on invested capital – – 0.4%
Return on capital employed – -9.8% 0.6%
Asset turnover 0.4x 0.6x 0.3x
Cash conversion (OCF / net income) 1.3x -1.7x 2.2x
Stock comp / revenue – 16.0% –

Financial Health

11 metrics
MetricTMOTXGBIO
Debt / assets – – 11.7%
Debt / equity – – 0.2x
Net debt / EBITDA – – –
Debt / FCF – – 3.4x
Liabilities / assets – 19.9% 30.0%
Equity / assets 47.9% 80.1% 70.0%
Interest coverage – – 1.1x
Current ratio 1.8x 5.7x 3.1x
Quick ratio – 0.8x 2.1x
Cash ratio – 0.4x 1.7x
Altman Z-score – 28.69 3.59

Shareholder Returns

7 metrics
MetricTMOTXGBIO
Dividend yield 0.3% – –
Net buyback yield – -0.1% 1.2%
Shareholder yield 0.3% -0.1% 1.2%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusTMOTXGBIO
Forward P/E 26.8xFY2026 – 38.3xFY2026
EPS, next fiscal year $25.91FY2026 $-0.79FY2026 $9.95FY2026
EPS growth, next FY +13.3%FY2026 – +0.3%FY2026
EPS growth, the year after +2.0% – -0.2%
Revenue, next fiscal year $50.12BFY2026 $580.42MFY2026 $2.69BFY2026
Revenue growth, next FY +12.5%FY2026 -9.7%FY2026 +4.2%FY2026
Revenue growth, the year after -2.8% +24.6% -6.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersTMOTXGBIO
Held by institutions 90.2% 100.0% 89.5%
Institutions holding 2,622 389 403
Change in shares held, QoQ +0.8% +2.4% -2.9%
Institutions buying 1,142 197 177
Institutions selling 1,144 137 155
Buyers to sellers 1.00 1.44 1.14

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

TMOTXGBIO
TMO 1.00 0.50 0.57
TXG 0.50 1.00 0.41
BIO 0.57 0.41 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, TMO, TXG and BIO?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: Thermo Fisher Scientific (TMO) $256.36B, 10x Genomics (TXG) $10.16B, Bio-Rad Laboratories (BIO) $10.19B.

Which stock is cheaper, TMO, TXG and BIO?

Thermo Fisher Scientific (TMO) trades on the lowest price-to-earnings ratio (Thermo Fisher Scientific (TMO) 36.4x, 10x Genomics (TXG) -135.0x, Bio-Rad Laboratories (BIO) 45.8x). On next year's consensus earnings, Thermo Fisher Scientific (TMO) is cheapest (Thermo Fisher Scientific (TMO) 26.8x, Bio-Rad Laboratories (BIO) 38.3x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Thermo Fisher Scientific (TMO) grew revenue fastest over the trailing twelve months: Thermo Fisher Scientific (TMO) +8.3%, 10x Genomics (TXG) -4.3%, Bio-Rad Laboratories (BIO) +1.4%.

Which company is more profitable?

Bio-Rad Laboratories (BIO) has the highest net margin (10x Genomics (TXG) -12.2%, Bio-Rad Laboratories (BIO) 8.6%).

Which stock has performed better?

Over the past year 10x Genomics (TXG) returned the most: Thermo Fisher Scientific (TMO) +23.0%, 10x Genomics (TXG) +474.1%, Bio-Rad Laboratories (BIO) +13.3%. Over five years, Thermo Fisher Scientific (TMO) compounded fastest (Thermo Fisher Scientific (TMO) +2.3%/yr, 10x Genomics (TXG) -13.9%/yr, Bio-Rad Laboratories (BIO) -13.6%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Thermo Fisher Scientific (TMO) 0.27%. 10x Genomics (TXG) and Bio-Rad Laboratories (BIO) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Thermo Fisher Scientific (TMO) has been the steadiest (Thermo Fisher Scientific (TMO) 29.8%, 10x Genomics (TXG) 73.9%, Bio-Rad Laboratories (BIO) 37.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, TMO, TXG and BIO?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Thermo Fisher Scientific (TMO) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.