TMO vs ECL vs RGEN Stock Comparison

Thermo Fisher Scientific, Ecolab and Repligen Prices as of Oct 26, 2026 Peers: Industry group
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ECL Ecolab Inc.
$288.96 +3.3% 1M +4.2% 1Y
Market cap
$82.10B
P/E
38.8x
Revenue (TTM)
$16.84B
Div. yield
0.01%
Water Treatment Industrials
4 wins
RGEN Repligen Corp
$180.17 -5.0% 1M +8.3% 1Y
Market cap
$9.92B
P/E
238.7x
Revenue (TTM)
$785.10M
Div. yield
–
Life Sciences Tools Healthcare
3 wins

Head to Head

11 decided of 12

Thermo Fisher Scientific leads on 4 of the 12 questions below (Thermo Fisher Scientific 4, Ecolab 4, Repligen 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionTMOECLRGENLeader
Larger companyMarket capitalisation $257.69B $82.10B $9.92B TMO
Cheaper on earningsLower P/E, profitable companies only 36.4x 38.8x 238.7x TMO
Cheaper on forward earningsLower price / next fiscal year consensus EPS 26.4x 36.6x 92.9x TMO
Faster revenue growthRevenue growth, trailing twelve months +8.3% +7.1% +16.5% RGEN
More profitableNet margin, trailing twelve months — 12.6% 5.3% ECL
Better return on capitalReturn on invested capital — 11.0% 1.9% ECL
Less leveragedLower net debt / EBITDA — 2.1x -1.6x RGEN
Higher dividend yieldTrailing dividend yield 0.00% 0.01% 0.00% –
Better 1-year returnPrice return, last 12 months +19.6% +4.2% +8.3% TMO
Better 5-year returnAnnualised price return, 5 years +2.3%/yr +5.5%/yr -7.8%/yr ECL
Less volatileAnnualised volatility, 1 year 29.9% 21.9% 46.3% ECL
Higher overall scoreMean of the five percentile scores vs peers 51/100 66/100 66/100 RGEN

Percentile Scorecard

TMOECLRGEN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisTMOECLRGEN
Valuation 49 #116 of 228 50 #11 of 21 54 #105 of 228
Growth 40 #133 of 221 83 #4 of 19 56 #98 of 221
Profitability 70 #63 of 208 88 #3 of 17 71 #61 of 208
Financial Health – 48 #12 of 22 80 #48 of 239
Shareholder Returns 44 #77 of 137 60 #5 of 11 68 #44 of 137
Overall 51 66 66
  • TMO ranked among 248 companies in Medical Devices and Diagnostics
  • ECL ranked among 22 companies in Environmental Equipment
  • RGEN ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodTMOECLRGENSPY
1 month +1.7%+3.3%-5.0% -0.8%
3 months +22.4%+6.3%+37.5% +3.5%
6 months +46.3%+7.9%+52.3% +7.0%
Year to date +18.2%+10.1%+10.0% +12.2%
1 year +19.6%+4.2%+8.3% +13.0%
3 years +58.7%+83.5%+50.7% +86.3%
3 years, per year +16.7%+22.5%+14.7% +23.1%
5 years +11.8%+30.7%-33.5% +68.6%
5 years, per year +2.3%+5.5%-7.8% +11.0%
10 years +362.6%+150.5%+525.2% +258.0%
10 years, per year +16.6%+9.6%+20.1% +13.6%

Risk

MeasureTMOECLRGENSPY
Volatility, 1Y 29.9%21.9%46.3% 12.7%
Downside volatility, 1Y 28.3%22.0%46.8% 12.7%
Beta vs S&P 500, 1Y 0.620.481.22 1.00
Return / volatility, 1Y 0.660.190.18 1.02
Max drawdown, 5Y -41.5%-44.3%-66.2% -25.4%
From 52-week high -1.7%-6.3%-7.4% -1.8%
52-week high $696.55$308.35$194.57 $779.14
52-week low $438.34$245.73$102.87 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleTMOECLRGEN
P/E now vs peer median 35.9xmedian 30.6x 38.3xmedian 25.6x 244.7xmedian 30.6x
P/S now vs peer median 5.3xmedian 3.0x 4.8xmedian 2.5x 12.9xmedian 3.0x
EV/EBITDA now vs peer median —median 17.5x 22.9xmedian 19.1x 61.6xmedian 17.5x
P/FCF now vs peer median 34.0xmedian 23.3x 43.2xmedian 25.2x 90.8xmedian 23.3x
P/B now vs peer median 4.6xmedian 2.4x 8.0xmedian 2.0x 4.8xmedian 2.4x
PEG now vs peer median 4.74median 0.87 1.72median 1.54 -8.04median 0.87

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsTMOECLRGEN
Revenue $47.35B $16.84B $785.10M
Gross profit – $7.43B $422.67M
Operating income $8.47B $2.85B $64.61M
Net income $7.09B $2.13B $41.54M
Free cash flow – $1.87B $111.97M
R&D $1.40B – $56.17M
EPS (diluted) $19.06 $7.50 $0.73
Cash & equivalents $5.46B $5.14B $606.78M
Total debt – $13.18B $551.05M
Shares (diluted) 371.00M 282.20M 56.64M
Enterprise value $257.69B $73.85B $6.81B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricTMOECLRGEN
P/E 35.9x 38.3x 244.7x
P/FCF 34.0x 43.2x 90.8x
P/Operating cash flow 27.2x 26.5x 75.4x
P/S 5.3x 4.8x 12.9x
P/B 4.6x 8.0x 4.8x
P/Tangible book 6.9x 12.2x 5.8x
EV/EBITDA – 22.9x 61.6x
EV/EBIT – 31.2x 153.3x
EV/Revenue 5.3x 5.3x 12.6x
EV/FCF – 47.5x 88.5x
EV/Operating cash flow 27.2x 29.1x 73.5x
PEG (3Y EPS CAGR) 4.74 1.72 -8.04

Growth

14 metrics
MetricTMOECLRGEN
Revenue growth (1Y) 8.3% 7.1% 16.5%
Revenue CAGR (3Y) 2.9% 4.5% 3.3%
Gross profit growth (1Y) – 7.5% 40.6%
Gross profit CAGR (3Y) – 9.4% 4.2%
Operating income growth (1Y) 12.8% -1.4% 370.8%
Operating income CAGR (3Y) 7.2% 18.4% -21.7%
Net income growth (1Y) 7.9% -1.0% 400.4%
Net income CAGR (3Y) 6.2% 21.3% -30.6%
EPS growth (1Y) 9.7% 0.2% 399.7%
EPS CAGR (3Y) 7.6% 22.3% -30.4%
Operating cash flow growth (1Y) 21.9% 16.5% 2.1%
Operating cash flow CAGR (3Y) 4.5% 13.9% -3.2%
Free cash flow growth (1Y) – 19.1% 2.8%
Free cash flow CAGR (3Y) – 12.2% 3.9%

Profitability

14 metrics
MetricTMOECLRGEN
Gross margin – 44.1% 53.8%
EBITDA margin – 23.1% 20.5%
Operating margin – 16.9% 8.2%
Pretax margin – 15.6% 6.6%
Net margin – 12.6% 5.3%
FCF margin – 11.1% 14.3%
Operating cash flow margin 19.7% 18.1% 17.2%
Return on equity 13.2% 21.2% 2.0%
Return on assets 6.2% 7.8% 1.4%
Return on invested capital – 11.0% 1.9%
Return on capital employed – 13.3% 2.3%
Asset turnover 0.4x 0.6x 0.3x
Cash conversion (OCF / net income) 1.3x 1.4x 3.2x
Stock comp / revenue – 0.8% 4.2%

Financial Health

11 metrics
MetricTMOECLRGEN
Debt / assets – 44.0% 18.7%
Debt / equity – 1.3x 0.3x
Net debt / EBITDA – 2.1x -1.6x
Debt / FCF – 7.0x 4.9x
Liabilities / assets – 66.3% 28.4%
Equity / assets 47.9% 33.7% 71.6%
Interest coverage – 17.6x 2.9x
Current ratio 1.8x 1.8x 9.1x
Quick ratio – 1.5x 7.3x
Cash ratio – 0.9x 6.1x
Altman Z-score – 4.15 8.27

Shareholder Returns

7 metrics
MetricTMOECLRGEN
Dividend yield 0.3% 1.0% –
Net buyback yield – 1.3% 0.0%
Shareholder yield 0.3% 2.3% 0.0%
Payout ratio (earnings) – 37.4% –
Payout ratio (FCF) – 42.6% –
Dividend growth (1Y) – 13.4% –
Dividend CAGR (3Y) – 9.3% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusTMOECLRGEN
Forward P/E 26.4xFY2026 36.6xFY2026 92.9xFY2026
EPS, next fiscal year $25.91FY2026 $7.90FY2026 $1.94FY2026
EPS growth, next FY +13.3%FY2026 +4.9%FY2026 +13.5%FY2026
EPS growth, the year after +2.0% +23.2% +29.4%
Revenue, next fiscal year $50.12BFY2026 $17.26BFY2026 $773.94MFY2026
Revenue growth, next FY +12.5%FY2026 +7.3%FY2026 +4.8%FY2026
Revenue growth, the year after -2.8% +5.4% +35.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersTMOECLRGEN
Held by institutions 90.2% 80.0% 100.0%
Institutions holding 2,621 1,710 482
Change in shares held, QoQ +0.8% +1.4% +1.2%
Institutions buying 1,141 762 272
Institutions selling 1,144 679 141
Buyers to sellers 1.00 1.12 1.93

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

TMOECLRGEN
TMO 1.00 0.22 0.67
ECL 0.22 1.00 0.28
RGEN 0.67 0.28 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, TMO, ECL and RGEN?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: Thermo Fisher Scientific (TMO) $257.69B, Ecolab (ECL) $82.10B, Repligen (RGEN) $9.92B.

Which stock is cheaper, TMO, ECL and RGEN?

Thermo Fisher Scientific (TMO) trades on the lowest price-to-earnings ratio (Thermo Fisher Scientific (TMO) 36.4x, Ecolab (ECL) 38.8x, Repligen (RGEN) 238.7x). On next year's consensus earnings, Thermo Fisher Scientific (TMO) is cheapest (Thermo Fisher Scientific (TMO) 26.4x, Ecolab (ECL) 36.6x, Repligen (RGEN) 92.9x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Repligen (RGEN) grew revenue fastest over the trailing twelve months: Thermo Fisher Scientific (TMO) +8.3%, Ecolab (ECL) +7.1%, Repligen (RGEN) +16.5%.

Which company is more profitable?

Ecolab (ECL) has the highest net margin (Ecolab (ECL) 12.6%, Repligen (RGEN) 5.3%). On return on invested capital, Ecolab (ECL) leads (Ecolab (ECL) 11.0%, Repligen (RGEN) 1.9%).

Which stock has performed better?

Over the past year Thermo Fisher Scientific (TMO) returned the most: Thermo Fisher Scientific (TMO) +19.6%, Ecolab (ECL) +4.2%, Repligen (RGEN) +8.3%. Over five years, Ecolab (ECL) compounded fastest (Thermo Fisher Scientific (TMO) +2.3%/yr, Ecolab (ECL) +5.5%/yr, Repligen (RGEN) -7.8%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Thermo Fisher Scientific (TMO) 0.00%, Ecolab (ECL) 0.01%, Repligen (RGEN) 0.00%. Thermo Fisher Scientific (TMO) and Repligen (RGEN) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Ecolab (ECL) has been the steadiest (Thermo Fisher Scientific (TMO) 29.9%, Ecolab (ECL) 21.9%, Repligen (RGEN) 46.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, TMO, ECL and RGEN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Thermo Fisher Scientific (TMO) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.