SRPT vs VCEL vs BEAM Stock Comparison

Sarepta Therapeutics, Vericel and Beam Therapeutics Prices as of Oct 28, 2026 Peers: Industry group
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VCEL Vericel Corp
$41.09 +2.1% 1M +11.6% 1Y
Market cap
$2.19B
P/E
90.2x
Revenue (TTM)
$306.30M
Div. yield
–
Gene and Cell Therapy Healthcare
5 wins
BEAM Beam Therapeutics Inc.
$28.78 +18.8% 1M +8.9% 1Y
Market cap
$2.99B
P/E
–
Revenue (TTM)
$156.04M
Div. yield
–
Gene and Cell Therapy Healthcare
2 wins

Head to Head

9 decided of 12

Vericel leads on 5 of the 12 questions below (Vericel 5, Beam Therapeutics 2, Sarepta Therapeutics 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSRPTVCELBEAMLeader
Larger companyMarket capitalisation $2.03B $2.19B $2.99B BEAM
Cheaper on earningsLower P/E, profitable companies only -17.3x 90.2x -35.0x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 6.7x 80.6x — SRPT
Faster revenue growthRevenue growth, trailing twelve months -20.4% +23.0% +158.9% BEAM
More profitableNet margin, trailing twelve months -5.9% 7.9% -54.7% VCEL
Better return on capitalReturn on invested capital -6.1% — — –
Less leveragedLower net debt / EBITDA -0.6x — 3.0x SRPT
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -20.2% +11.6% +8.9% VCEL
Better 5-year returnAnnualised price return, 5 years -24.6%/yr -2.2%/yr -20.2%/yr VCEL
Less volatileAnnualised volatility, 1 year 81.1% 41.1% 70.7% VCEL
Higher overall scoreMean of the five percentile scores vs peers 67/100 81/100 69/100 VCEL

Percentile Scorecard

SRPTVCELBEAM

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSRPTVCELBEAM
Valuation 96 #25 of 625 82 #112 of 625 57 #272 of 625
Growth 64 #217 of 602 94 #38 of 602 77 #139 of 602
Profitability 79 #114 of 549 88 #65 of 549 64 #197 of 549
Financial Health 33 #436 of 654 69 #206 of 654 81 #123 of 654
Shareholder Returns 61 #145 of 367 73 #100 of 367 68 #119 of 367
Overall 67 81 69
  • SRPT ranked among 672 companies in Pharmaceuticals and Biotechnology
  • VCEL ranked among 672 companies in Pharmaceuticals and Biotechnology
  • BEAM ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSRPTVCELBEAMSPY
1 month +2.8%+2.1%+18.8% +0.9%
3 months +24.4%-11.9%+10.6% +5.9%
6 months -6.5%+22.9%-2.0% +8.5%
Year to date -10.2%+14.1%+3.8% +13.3%
1 year -20.2%+11.6%+8.9% +12.4%
3 years -81.9%+25.2%+54.6% +88.1%
3 years, per year -43.5%+7.8%+15.6% +23.5%
5 years -75.6%-10.7%-67.6% +68.2%
5 years, per year -24.6%-2.2%-20.2% +11.0%
10 years -52.8%+1,648.5%— +263.4%
10 years, per year -7.2%+33.1%— +13.8%

Risk

MeasureSRPTVCELBEAMSPY
Volatility, 1Y 81.1%41.1%70.7% 12.7%
Downside volatility, 1Y 85.9%40.6%64.0% 12.7%
Beta vs S&P 500, 1Y 2.080.732.09 1.00
Return / volatility, 1Y -0.250.280.13 0.98
Max drawdown, 5Y -92.7%-64.7%-85.3% -25.4%
From 52-week high -21.0%-14.9%-24.1% -0.9%
52-week high $24.45$48.31$37.92 $779.14
52-week low $14.86$29.34$20.60 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSRPTVCELBEAM
P/E now vs peer median -17.4xmedian 17.4x 86.6xmedian 17.4x -35.1xmedian 17.4x
P/S now vs peer median 1.0xmedian 9.1x 6.9xmedian 9.1x 19.0xmedian 9.1x
EV/EBITDA now vs peer median -21.3xmedian 17.1x 61.8xmedian 17.1x -5.4xmedian 17.1x
P/FCF now vs peer median 24.9xmedian 19.0x 34.1xmedian 19.0x -8.0xmedian 19.0x
P/B now vs peer median 1.3xmedian 2.2x 5.7xmedian 2.2x 2.8xmedian 2.2x
PEG now vs peer median -0.33median 0.34 1.60median 0.34 -0.83median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSRPTVCELBEAM
Revenue $1.97B $306.30M $156.04M
Gross profit $1.17B $228.38M –
Operating income -$143.25M $18.24M -$378.02M
Net income -$136.73M $24.22M -$86.52M
Free cash flow $81.85M $61.66M -$372.77M
R&D $789.44M $29.17M $408.66M
EPS (diluted) $-1.11 $0.46 $-0.82
Cash & equivalents $571.15M $125.40M $219.83M
Total debt $847.62M – $100.26M
Shares (diluted) 105.43M 52.31M 104.33M
Enterprise value -$1.21B $1.60B -$1.69B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSRPTVCELBEAM
P/E -17.4x 86.6x -35.1x
P/FCF 24.9x 34.1x -8.0x
P/Operating cash flow 18.4x 30.2x -8.3x
P/S 1.0x 6.9x 19.0x
P/B 1.3x 5.7x 2.8x
P/Tangible book 1.4x 5.8x 2.8x
EV/EBITDA -21.3x 61.8x -5.4x
EV/EBIT -14.7x 106.4x -5.1x
EV/Revenue 1.1x 6.3x 12.3x
EV/FCF 25.7x 31.5x -5.1x
EV/Operating cash flow 18.9x 27.8x -5.3x
PEG (3Y EPS CAGR) -0.33 1.60 -0.83

Growth

14 metrics
MetricSRPTVCELBEAM
Revenue growth (1Y) -20.4% 23.0% 158.9%
Revenue CAGR (3Y) 25.3% 19.8% 24.9%
Gross profit growth (1Y) -40.7% 24.8% –
Gross profit CAGR (3Y) 10.6% 23.9% –
Operating income growth (1Y) -15,270% 1,428% 15.2%
Operating income CAGR (3Y) 34.5% 47.8% 0.3%
Net income growth (1Y) -135.9% 240.8% 78.2%
Net income CAGR (3Y) 46.8% 56.6% 35.8%
EPS growth (1Y) -215.7% 228.1% 79.0%
EPS CAGR (3Y) 52.3% 54.3% 42.4%
Operating cash flow growth (1Y) 136.9% 47.5% -4.2%
Operating cash flow CAGR (3Y) 30.6% 33.7% -2.0%
Free cash flow growth (1Y) 118.1% 842.9% -4.8%
Free cash flow CAGR (3Y) 29.1% 43.2% 0.7%

Profitability

14 metrics
MetricSRPTVCELBEAM
Gross margin 59.1% 74.6% –
EBITDA margin -5.0% 10.2% -228.0%
Operating margin -7.3% 6.0% -242.3%
Pretax margin -6.6% 8.2% -54.4%
Net margin -5.9% 7.9% -54.7%
FCF margin 4.1% 20.1% -238.9%
Operating cash flow margin 5.6% 22.7% -230.3%
Return on equity -9.0% 6.9% -7.6%
Return on assets -4.3% 5.1% -5.9%
Return on invested capital -6.1% – –
Return on capital employed -5.3% 4.1% -27.9%
Asset turnover 0.6x 0.6x 0.1x
Cash conversion (OCF / net income) -0.8x 2.9x 4.2x
Stock comp / revenue 6.3% 12.2% 52.2%

Financial Health

11 metrics
MetricSRPTVCELBEAM
Debt / assets 26.6% – 7.2%
Debt / equity 0.6x – 0.1x
Net debt / EBITDA -0.6x – 3.0x
Debt / FCF 10.4x – -0.3x
Liabilities / assets 52.1% 26.4% 23.0%
Equity / assets 47.9% 73.6% 77.0%
Interest coverage – 28.5x –
Current ratio 4.4x 5.0x 14.6x
Quick ratio 2.4x 4.5x 14.3x
Cash ratio 1.6x 3.1x 14.3x
Altman Z-score -0.14 9.67 3.84

Shareholder Returns

7 metrics
MetricSRPTVCELBEAM
Dividend yield – – –
Net buyback yield -1.1% -0.3% -0.5%
Shareholder yield -1.1% -0.3% -0.5%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSRPTVCELBEAM
Forward P/E 6.7xFY2026 80.6xFY2026 –
EPS, next fiscal year $2.88FY2026 $0.51FY2026 $-4.22FY2026
EPS growth, next FY – +59.4%FY2026 –
EPS growth, the year after -88.5% +74.5% –
Revenue, next fiscal year $1.76BFY2026 $324.56MFY2026 $49.46MFY2026
Revenue growth, next FY -20.1%FY2026 +17.5%FY2026 -64.6%FY2026
Revenue growth, the year after -21.5% +16.1% +23.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSRPTVCELBEAM
Held by institutions 100.0% 100.0% 100.0%
Institutions holding 324 317 277
Change in shares held, QoQ +4.5% +0.4% +1.0%
Institutions buying 148 187 154
Institutions selling 115 98 75
Buyers to sellers 1.29 1.91 2.05

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SRPTVCELBEAM
SRPT 1.00 0.19 0.36
VCEL 0.19 1.00 0.20
BEAM 0.36 0.20 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, SRPT, VCEL and BEAM?

Beam Therapeutics (BEAM) is the largest by market capitalisation: Sarepta Therapeutics (SRPT) $2.03B, Vericel (VCEL) $2.19B, Beam Therapeutics (BEAM) $2.99B.

Which company is growing faster?

Beam Therapeutics (BEAM) grew revenue fastest over the trailing twelve months: Sarepta Therapeutics (SRPT) -20.4%, Vericel (VCEL) +23.0%, Beam Therapeutics (BEAM) +158.9%.

Which company is more profitable?

Vericel (VCEL) has the highest net margin (Sarepta Therapeutics (SRPT) -5.9%, Vericel (VCEL) 7.9%, Beam Therapeutics (BEAM) -54.7%).

Which stock has performed better?

Over the past year Vericel (VCEL) returned the most: Sarepta Therapeutics (SRPT) -20.2%, Vericel (VCEL) +11.6%, Beam Therapeutics (BEAM) +8.9%. Over five years, Vericel (VCEL) compounded fastest (Sarepta Therapeutics (SRPT) -24.6%/yr, Vericel (VCEL) -2.2%/yr, Beam Therapeutics (BEAM) -20.2%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Vericel (VCEL) has been the steadiest (Sarepta Therapeutics (SRPT) 81.1%, Vericel (VCEL) 41.1%, Beam Therapeutics (BEAM) 70.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SRPT, VCEL and BEAM?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Vericel (VCEL) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.