SLDB vs VCEL vs CRSP Stock Comparison

Solid Biosciences, Vericel and CRISPR Therapeutics AG Prices as of Oct 29, 2026 Peers: Industry group
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SLDB Solid Biosciences Inc.
$6.39 -10.8% 1M +16.4% 1Y
Market cap
$888.71M
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
VCEL Vericel Corp
$42.91 +5.7% 1M +23.0% 1Y
Market cap
$2.05B
P/E
84.7x
Revenue (TTM)
$306.30M
Div. yield
–
Gene and Cell Therapy Healthcare
6 wins
CRSP CRISPR Therapeutics AG
$54.26 -3.1% 1M -13.3% 1Y
Market cap
$4.94B
P/E
–
Revenue (TTM)
$13.39M
Div. yield
–
Gene and Cell Therapy Healthcare
1 win

Head to Head

7 decided of 12

Vericel leads on 6 of the 12 questions below (Vericel 6, CRISPR Therapeutics AG 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSLDBVCELCRSPLeader
Larger companyMarket capitalisation $888.71M $2.05B $4.94B CRSP
Cheaper on earningsLower P/E, profitable companies only -4.3x 84.7x -11.0x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 84.1x — –
Faster revenue growthRevenue growth, trailing twelve months — +23.0% -64.8% VCEL
More profitableNet margin, trailing twelve months — 7.9% -3,368.7% VCEL
Better return on capitalReturn on invested capital — — -22.6% –
Less leveragedLower net debt / EBITDA — — 3.4x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +16.4% +23.0% -13.3% VCEL
Better 5-year returnAnnualised price return, 5 years -26.8%/yr -1.4%/yr -9.9%/yr VCEL
Less volatileAnnualised volatility, 1 year 78.2% 41.0% 57.3% VCEL
Higher overall scoreMean of the five percentile scores vs peers 42/100 81/100 45/100 VCEL

Percentile Scorecard

SLDBVCELCRSP

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSLDBVCELCRSP
Valuation 35 #408 of 624 82 #115 of 624 51 #308 of 624
Growth 20 #484 of 601 94 #36 of 601 32 #412 of 601
Profitability 50 #273 of 541 88 #64 of 541 32 #367 of 541
Financial Health 88 #77 of 647 69 #203 of 647 71 #188 of 647
Shareholder Returns 19 #292 of 359 73 #99 of 359 38 #222 of 359
Overall 42 81 45
  • SLDB ranked among 671 companies in Pharmaceuticals and Biotechnology
  • VCEL ranked among 671 companies in Pharmaceuticals and Biotechnology
  • CRSP ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSLDBVCELCRSPSPY
1 month -10.8%+5.7%-3.1% +0.7%
3 months -24.7%-9.9%+12.0% +3.7%
6 months -12.0%+23.6%+3.7% +7.1%
Year to date +13.3%+19.2%+3.5% +12.8%
1 year +16.4%+23.0%-13.3% +11.9%
3 years +208.7%+24.8%+39.4% +85.2%
3 years, per year +45.6%+7.7%+11.7% +22.8%
5 years -79.0%-6.8%-40.6% +67.6%
5 years, per year -26.8%-1.4%-9.9% +10.9%
10 years —+1,726.0%+224.1% +262.0%
10 years, per year —+33.7%+12.5% +13.7%

Risk

MeasureSLDBVCELCRSPSPY
Volatility, 1Y 78.2%41.0%57.3% 12.7%
Downside volatility, 1Y 76.3%40.0%53.8% 12.6%
Beta vs S&P 500, 1Y 2.130.711.84 1.00
Return / volatility, 1Y 0.210.56-0.23 0.94
Max drawdown, 5Y -94.9%-64.7%-67.7% -25.4%
From 52-week high -42.7%-11.2%-15.2% -1.2%
52-week high $11.15$48.31$63.99 $779.14
52-week low $3.93$29.34$44.34 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSLDBVCELCRSP
P/E now vs peer median -4.4xmedian 17.8x 90.5xmedian 17.8x -11.6xmedian 17.8x
P/S now vs peer median —median 9.1x 7.2xmedian 9.1x 391.6xmedian 9.1x
EV/EBITDA now vs peer median -2.6xmedian 15.0x 64.8xmedian 15.0x -6.7xmedian 15.0x
P/FCF now vs peer median -4.9xmedian 21.7x 35.6xmedian 21.7x -14.1xmedian 21.7x
P/B now vs peer median 2.5xmedian 2.2x 5.9xmedian 2.2x 3.0xmedian 2.2x
PEG now vs peer median -0.14median 0.35 1.67median 0.35 -3.01median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSLDBVCELCRSP
Revenue – $306.30M $13.39M
Gross profit – $228.38M –
Operating income -$212.15M $18.24M -$534.34M
Net income -$207.10M $24.22M -$451.14M
Free cash flow -$187.82M $61.66M -$371.33M
R&D $167.40M $29.17M $278.15M
EPS (diluted) $-1.44 $0.46 $-4.67
Cash & equivalents $159.39M $125.40M $291.34M
Total debt – – $586.20M
Shares (diluted) 143.69M 52.31M 96.51M
Enterprise value -$293.64M $1.47B -$3.76B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSLDBVCELCRSP
P/E -4.4x 90.5x -11.6x
P/FCF -4.9x 35.6x -14.1x
P/Operating cash flow -4.9x 31.5x -14.2x
P/S – 7.2x 391.6x
P/B 2.5x 5.9x 3.0x
P/Tangible book 2.5x 6.0x 3.0x
EV/EBITDA -2.6x 64.8x -6.7x
EV/EBIT -2.5x 111.5x -6.5x
EV/Revenue – 6.6x 258.9x
EV/FCF -2.9x 33.0x -9.3x
EV/Operating cash flow -2.9x 29.2x -9.4x
PEG (3Y EPS CAGR) -0.14 1.67 -3.01

Growth

14 metrics
MetricSLDBVCELCRSP
Revenue growth (1Y) – 23.0% -64.8%
Revenue CAGR (3Y) – 19.8% -57.1%
Gross profit growth (1Y) – 24.8% –
Gross profit CAGR (3Y) – 23.9% –
Operating income growth (1Y) -35.3% 1,428% 3.3%
Operating income CAGR (3Y) -22.8% 47.8% -4.1%
Net income growth (1Y) -34.4% 240.8% 3.6%
Net income CAGR (3Y) -31.9% 56.6% -2.7%
EPS growth (1Y) 11.9% 228.1% 13.0%
EPS CAGR (3Y) 32.0% 54.3% 3.9%
Operating cash flow growth (1Y) -52.4% 47.5% -13.8%
Operating cash flow CAGR (3Y) -19.2% 33.7% -2.5%
Free cash flow growth (1Y) -52.3% 842.9% -14.1%
Free cash flow CAGR (3Y) -18.4% 43.2% -0.9%

Profitability

14 metrics
MetricSLDBVCELCRSP
Gross margin – 74.6% –
EBITDA margin – 10.2% -3,850%
Operating margin – 6.0% -3,990%
Pretax margin – 8.2% -3,346%
Net margin – 7.9% -3,369%
FCF margin – 20.1% -2,773%
Operating cash flow margin – 22.7% -2,760%
Return on equity -55.4% 6.9% -25.3%
Return on assets -49.1% 5.1% -16.8%
Return on invested capital – – -22.6%
Return on capital employed -54.0% 4.1% -20.9%
Asset turnover – 0.6x 0.0x
Cash conversion (OCF / net income) 0.9x 2.9x 0.8x
Stock comp / revenue – 12.2% 510.2%

Financial Health

11 metrics
MetricSLDBVCELCRSP
Debt / assets – – 22.1%
Debt / equity – – 0.3x
Net debt / EBITDA – – 3.4x
Debt / FCF – – -1.6x
Liabilities / assets 11.1% 26.4% 34.1%
Equity / assets 88.9% 73.6% 65.9%
Interest coverage – 28.5x –
Current ratio 13.8x 5.0x 17.8x
Quick ratio 13.2x 4.5x 17.8x
Cash ratio 13.2x 3.1x 17.8x
Altman Z-score – 10.09 2.69

Shareholder Returns

7 metrics
MetricSLDBVCELCRSP
Dividend yield – – –
Net buyback yield -26.2% -0.3% -8.1%
Shareholder yield -26.2% -0.3% -8.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSLDBVCELCRSP
Forward P/E – 84.1xFY2026 –
EPS, next fiscal year $-1.63FY2026 $0.51FY2026 $-4.10FY2026
EPS growth, next FY – +59.4%FY2026 –
EPS growth, the year after – +74.5% –
Revenue, next fiscal year $0.00FY2026 $324.56MFY2026 $38.73MFY2026
Revenue growth, next FY – +17.5%FY2026 +1,003.4%FY2026
Revenue growth, the year after – +16.1% +266.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSLDBVCELCRSP
Held by institutions 79.7% 100.0% 78.9%
Institutions holding 157 318 519
Change in shares held, QoQ +18.9% +0.4% -1.0%
Institutions buying 101 188 238
Institutions selling 37 98 139
Buyers to sellers 2.73 1.92 1.71

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SLDBVCELCRSP
SLDB 1.00 0.19 0.50
VCEL 0.19 1.00 0.33
CRSP 0.50 0.33 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, SLDB, VCEL and CRSP?

CRISPR Therapeutics AG (CRSP) is the largest by market capitalisation: Solid Biosciences (SLDB) $888.71M, Vericel (VCEL) $2.05B, CRISPR Therapeutics AG (CRSP) $4.94B.

Which company is growing faster?

Vericel (VCEL) grew revenue fastest over the trailing twelve months: Vericel (VCEL) +23.0%, CRISPR Therapeutics AG (CRSP) -64.8%.

Which company is more profitable?

Vericel (VCEL) has the highest net margin (Vericel (VCEL) 7.9%, CRISPR Therapeutics AG (CRSP) -3,368.7%).

Which stock has performed better?

Over the past year Vericel (VCEL) returned the most: Solid Biosciences (SLDB) +16.4%, Vericel (VCEL) +23.0%, CRISPR Therapeutics AG (CRSP) -13.3%. Over five years, Vericel (VCEL) compounded fastest (Solid Biosciences (SLDB) -26.8%/yr, Vericel (VCEL) -1.4%/yr, CRISPR Therapeutics AG (CRSP) -9.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Vericel (VCEL) has been the steadiest (Solid Biosciences (SLDB) 78.2%, Vericel (VCEL) 41.0%, CRISPR Therapeutics AG (CRSP) 57.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SLDB, VCEL and CRSP?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Vericel (VCEL) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.