SLDB vs SLBT vs SRPT Stock Comparison

Solid Biosciences, SL Science Holding and Sarepta Therapeutics Prices as of Oct 29, 2026 Peers: Industry group
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SLDB Solid Biosciences Inc.
$6.39 -10.8% 1M +16.4% 1Y
Market cap
$888.71M
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
2 wins
SLBT SL Science Holding Ltd
$1.17 -36.1% 1M -88.7% 1Y
Market cap
$2.82B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
1 win

Head to Head

5 decided of 12

Solid Biosciences leads on 2 of the 12 questions below (Solid Biosciences 2, Sarepta Therapeutics 2, SL Science Holding 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSLDBSLBTSRPTLeader
Larger companyMarket capitalisation $888.71M $2.82B $1.96B SLBT
Cheaper on earningsLower P/E, profitable companies only -4.3x — -16.8x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 6.7x –
Faster revenue growthRevenue growth, trailing twelve months — — -20.4% –
More profitableNet margin, trailing twelve months — — -5.9% –
Better return on capitalReturn on invested capital — — -6.1% –
Less leveragedLower net debt / EBITDA — — -0.6x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +16.4% -88.7% -18.0% SLDB
Better 5-year returnAnnualised price return, 5 years -26.8%/yr — -24.7%/yr SRPT
Less volatileAnnualised volatility, 1 year 78.2% 175.5% 81.1% SLDB
Higher overall scoreMean of the five percentile scores vs peers 42/100 — 67/100 SRPT

Percentile Scorecard

SLDBSLBTSRPT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSLDBSLBTSRPT
Valuation 35 #408 of 624 11 #556 of 624 97 #23 of 624
Growth 20 #484 of 601 – 64 #220 of 601
Profitability 50 #273 of 541 – 80 #111 of 541
Financial Health 88 #77 of 647 58 #271 of 647 34 #430 of 647
Shareholder Returns 19 #292 of 359 – 61 #141 of 359
Overall 42 – 67
  • SLDB ranked among 671 companies in Pharmaceuticals and Biotechnology
  • SLBT ranked among 671 companies in Pharmaceuticals and Biotechnology
  • SRPT ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSLDBSLBTSRPTSPY
1 month -10.8%-36.1%+3.2% +0.7%
3 months -24.7%-56.5%+23.6% +3.7%
6 months -12.0%-87.4%-7.9% +7.1%
Year to date +13.3%-88.9%-10.6% +12.8%
1 year +16.4%-88.7%-18.0% +11.9%
3 years +208.7%—-82.1% +85.2%
3 years, per year +45.6%—-43.7% +22.8%
5 years -79.0%—-75.7% +67.6%
5 years, per year -26.8%—-24.7% +10.9%
10 years ——-53.0% +262.0%
10 years, per year ——-7.3% +13.7%

Risk

MeasureSLDBSLBTSRPTSPY
Volatility, 1Y 78.2%175.5%81.1% 12.7%
Downside volatility, 1Y 76.3%170.0%85.8% 12.6%
Beta vs S&P 500, 1Y 2.130.242.08 1.00
Return / volatility, 1Y 0.21-0.51-0.22 0.94
Max drawdown, 5Y -94.9%-91.0%-92.7% -25.4%
From 52-week high -42.7%-90.9%-21.3% -1.2%
52-week high $11.15$12.81$24.45 $779.14
52-week low $3.93$1.15$14.86 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSLDBSLBTSRPT
P/E now vs peer median -4.4xmedian 17.8x —median 17.8x -17.4xmedian 17.8x
P/S now vs peer median —median 9.1x —median 9.1x 1.0xmedian 9.1x
EV/EBITDA now vs peer median -2.6xmedian 15.0x —median 15.0x -21.2xmedian 15.0x
P/FCF now vs peer median -4.9xmedian 21.7x -1,359xmedian 21.7x 24.8xmedian 21.7x
P/B now vs peer median 2.5xmedian 2.2x 365.9xmedian 2.2x 1.3xmedian 2.2x
PEG now vs peer median -0.14median 0.35 —median 0.35 -0.33median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSLDBSLBTSRPT
Revenue – – $1.97B
Gross profit – – $1.17B
Operating income -$212.15M – -$143.25M
Net income -$207.10M – -$136.73M
Free cash flow -$187.82M – $81.85M
R&D $167.40M – $789.44M
EPS (diluted) $-1.44 – $-1.11
Cash & equivalents $159.39M $8.31M $571.15M
Total debt – – $847.62M
Shares (diluted) 143.69M – 105.43M
Enterprise value -$293.64M $2.80B -$1.27B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSLDBSLBTSRPT
P/E -4.4x – -17.4x
P/FCF -4.9x -1,359x 24.8x
P/Operating cash flow -4.9x – 18.3x
P/S – – 1.0x
P/B 2.5x 365.9x 1.3x
P/Tangible book 2.5x 365.9x 1.4x
EV/EBITDA -2.6x – -21.2x
EV/EBIT -2.5x – -14.6x
EV/Revenue – – 1.1x
EV/FCF -2.9x – 25.5x
EV/Operating cash flow -2.9x – 18.8x
PEG (3Y EPS CAGR) -0.14 – -0.33

Growth

14 metrics
MetricSLDBSLBTSRPT
Revenue growth (1Y) – – -20.4%
Revenue CAGR (3Y) – – 25.3%
Gross profit growth (1Y) – – -40.7%
Gross profit CAGR (3Y) – – 10.6%
Operating income growth (1Y) -35.3% – -15,270%
Operating income CAGR (3Y) -22.8% – 34.5%
Net income growth (1Y) -34.4% – -135.9%
Net income CAGR (3Y) -31.9% – 46.8%
EPS growth (1Y) 11.9% – -215.7%
EPS CAGR (3Y) 32.0% – 52.3%
Operating cash flow growth (1Y) -52.4% – 136.9%
Operating cash flow CAGR (3Y) -19.2% – 30.6%
Free cash flow growth (1Y) -52.3% – 118.1%
Free cash flow CAGR (3Y) -18.4% – 29.1%

Profitability

14 metrics
MetricSLDBSLBTSRPT
Gross margin – – 59.1%
EBITDA margin – – -5.0%
Operating margin – – -7.3%
Pretax margin – – -6.6%
Net margin – – -5.9%
FCF margin – – 4.1%
Operating cash flow margin – – 5.6%
Return on equity -55.4% – -9.0%
Return on assets -49.1% – -4.3%
Return on invested capital – – -6.1%
Return on capital employed -54.0% – -5.3%
Asset turnover – – 0.6x
Cash conversion (OCF / net income) 0.9x – -0.8x
Stock comp / revenue – – 6.3%

Financial Health

11 metrics
MetricSLDBSLBTSRPT
Debt / assets – – 26.6%
Debt / equity – – 0.6x
Net debt / EBITDA – – -0.6x
Debt / FCF – – 10.4x
Liabilities / assets 11.1% 21.8% 52.1%
Equity / assets 88.9% 78.2% 47.9%
Interest coverage – – –
Current ratio 13.8x 4.4x 4.4x
Quick ratio 13.2x 4.3x 2.4x
Cash ratio 13.2x 4.3x 1.6x
Altman Z-score – – -0.15

Shareholder Returns

7 metrics
MetricSLDBSLBTSRPT
Dividend yield – – –
Net buyback yield -26.2% – -1.1%
Shareholder yield -26.2% 0.0% -1.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSLDBSLBTSRPT
Forward P/E – – 6.7xFY2026
EPS, next fiscal year $-1.63FY2026 – $2.88FY2026
EPS growth, the year after – – -88.5%
Revenue, next fiscal year $0.00FY2026 – $1.76BFY2026
Revenue growth, next FY – – -20.1%FY2026
Revenue growth, the year after – – -21.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSLDBSLBTSRPT
Held by institutions 79.7% – 100.0%
Institutions holding 157 – 325
Change in shares held, QoQ +18.9% – +4.5%
Institutions buying 101 – 148
Institutions selling 37 – 116
Buyers to sellers 2.73 – 1.28

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SLDBSLBTSRPT
SLDB 1.00 -0.02 0.46
SLBT -0.02 1.00 0.00
SRPT 0.46 0.00 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, SLDB, SLBT and SRPT?

SL Science Holding (SLBT) is the largest by market capitalisation: Solid Biosciences (SLDB) $888.71M, SL Science Holding (SLBT) $2.82B, Sarepta Therapeutics (SRPT) $1.96B.

Which stock has performed better?

Over the past year Solid Biosciences (SLDB) returned the most: Solid Biosciences (SLDB) +16.4%, SL Science Holding (SLBT) -88.7%, Sarepta Therapeutics (SRPT) -18.0%. Over five years, Sarepta Therapeutics (SRPT) compounded fastest (Solid Biosciences (SLDB) -26.8%/yr, Sarepta Therapeutics (SRPT) -24.7%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Solid Biosciences (SLDB) has been the steadiest (Solid Biosciences (SLDB) 78.2%, SL Science Holding (SLBT) 175.5%, Sarepta Therapeutics (SRPT) 81.1%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SLDB, SLBT and SRPT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Solid Biosciences (SLDB) leads on 2. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.