SLDB vs IOVA vs PGEN Stock Comparison

Solid Biosciences, Iovance Biotherapeutics and Precigen Prices as of Nov 5, 2026 Peers: Industry group
1 more company in this comparison (SLBT) Create a free account to keep reading and compare up to 10 companies.
SLDB Solid Biosciences Inc.
$6.16 -11.0% 1M +56.7% 1Y
Market cap
$1.00B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
1 win
PGEN Precigen, Inc.
$4.22 -44.1% 1M +5.8% 1Y
Market cap
$1.57B
P/E
64.5x
Revenue (TTM)
$156.94M
Div. yield
–
Gene and Cell Therapy Healthcare
4 wins

Head to Head

7 decided of 12

Precigen leads on 4 of the 12 questions below (Precigen 4, Iovance Biotherapeutics 2, Solid Biosciences 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSLDBIOVAPGENLeader
Larger companyMarket capitalisation $1.00B $3.66B $1.57B IOVA
Cheaper on earningsLower P/E, profitable companies only -4.7x -16.6x 64.5x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 24.8x –
Faster revenue growthRevenue growth, trailing twelve months — +51.3% +2,387.6% PGEN
More profitableNet margin, trailing twelve months — -58.2% 15.6% PGEN
Better return on capitalReturn on invested capital — — 21.1% –
Less leveragedLower net debt / EBITDA — — 1.2x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +56.7% +327.6% +5.8% IOVA
Better 5-year returnAnnualised price return, 5 years -29.5%/yr -20.9%/yr -3.8%/yr PGEN
Less volatileAnnualised volatility, 1 year 75.9% 109.9% 85.7% SLDB
Higher overall scoreMean of the five percentile scores vs peers 42/100 67/100 72/100 PGEN

Percentile Scorecard

SLDBIOVAPGEN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSLDBIOVAPGEN
Valuation 38 #395 of 634 70 #190 of 634 68 #206 of 634
Growth 21 #482 of 608 91 #58 of 608 90 #59 of 608
Profitability 45 #307 of 557 67 #182 of 557 86 #81 of 557
Financial Health 86 #90 of 654 68 #213 of 654 38 #409 of 654
Shareholder Returns 20 #324 of 403 39 #245 of 403 77 #92 of 403
Overall 42 67 72
  • SLDB ranked among 671 companies in Pharmaceuticals and Biotechnology
  • IOVA ranked among 671 companies in Pharmaceuticals and Biotechnology
  • PGEN ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSLDBIOVAPGENSPY
1 month -11.0%-40.3%-44.1% -5.9%
3 months -29.3%+24.6%-38.9% -4.6%
6 months -12.9%+118.0%+1.7% +0.2%
Year to date +9.2%+183.5%+1.0% +7.5%
1 year +56.7%+327.6%+5.8% +8.2%
3 years +124.0%+79.2%+263.8% +68.3%
3 years, per year +30.9%+21.5%+53.8% +19.0%
5 years -82.6%-69.0%-17.4% +56.5%
5 years, per year -29.5%-20.9%-3.8% +9.4%
10 years —+33.4%-83.2% +251.5%
10 years, per year —+2.9%-16.4% +13.4%

Risk

MeasureSLDBIOVAPGENSPY
Volatility, 1Y 75.9%109.9%85.7% 13.6%
Downside volatility, 1Y 71.4%95.6%84.2% 14.2%
Beta vs S&P 500, 1Y 1.961.601.63 1.00
Return / volatility, 1Y 0.752.980.07 0.60
Max drawdown, 5Y -94.5%-93.4%-86.5% -25.4%
From 52-week high -44.8%-47.9%-50.7% -5.9%
52-week high $11.15$14.86$8.56 $779.14
52-week low $3.93$1.81$3.10 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSLDBIOVAPGEN
P/E now vs peer median -4.3xmedian 17.8x -16.0xmedian 17.8x 61.9xmedian 17.8x
P/S now vs peer median —median 8.1x 9.4xmedian 8.1x 9.6xmedian 8.1x
EV/EBITDA now vs peer median -2.6xmedian 15.7x -16.6xmedian 15.7x 39.6xmedian 15.7x
P/FCF now vs peer median -4.6xmedian 21.0x -16.6xmedian 21.0x -20.4xmedian 21.0x
P/B now vs peer median 2.7xmedian 2.0x 4.4xmedian 2.0x 18.1xmedian 2.0x
PEG now vs peer median -0.14median 0.36 -0.46median 0.36 2.10median 0.36

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSLDBIOVAPGEN
Revenue – $378.98M $156.94M
Gross profit – $201.75M $143.48M
Operating income -$221.75M -$230.38M $33.63M
Net income -$215.27M -$220.56M $24.41M
Free cash flow -$200.31M -$216.07M -$74.32M
R&D $172.14M $241.88M $26.54M
EPS (diluted) $-1.43 $-0.48 $0.06
Cash & equivalents $125.97M $57.93M $14.96M
Total debt – – $94.26M
Shares (diluted) 151.03M 455.92M 421.16M
Enterprise value -$292.29M $2.38B $1.34B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSLDBIOVAPGEN
P/E -4.3x -16.0x 61.9x
P/FCF -4.6x -16.6x -20.4x
P/Operating cash flow -4.7x -18.9x -20.7x
P/S – 9.4x 9.6x
P/B 2.7x 4.4x 18.1x
P/Tangible book 2.7x 6.5x 18.5x
EV/EBITDA -2.6x -16.6x 39.6x
EV/EBIT -2.6x -13.9x 46.4x
EV/Revenue – 8.5x 9.9x
EV/FCF -2.9x -14.8x -21.0x
EV/Operating cash flow -2.9x -16.9x -21.3x
PEG (3Y EPS CAGR) -0.14 -0.46 2.10

Growth

14 metrics
MetricSLDBIOVAPGEN
Revenue growth (1Y) – 51.3% 2,388%
Revenue CAGR (3Y) – 712.3% 185.3%
Gross profit growth (1Y) – 144.4% 7,400%
Gross profit CAGR (3Y) – – 478.3%
Operating income growth (1Y) -30.7% 44.7% 128.7%
Operating income CAGR (3Y) -23.9% 19.8% 33.6%
Net income growth (1Y) -28.8% 44.5% 109.9%
Net income CAGR (3Y) -33.3% 20.1% 31.8%
EPS growth (1Y) 19.5% 55.7% 104.2%
EPS CAGR (3Y) 32.0% 35.0% 29.5%
Operating cash flow growth (1Y) -50.3% 41.2% -0.8%
Operating cash flow CAGR (3Y) -22.6% 18.9% -3.2%
Free cash flow growth (1Y) -50.4% 38.6% 1.7%
Free cash flow CAGR (3Y) -22.1% 17.0% -3.5%

Profitability

14 metrics
MetricSLDBIOVAPGEN
Gross margin – 53.2% 91.4%
EBITDA margin – -50.9% 25.1%
Operating margin – -60.8% 21.4%
Pretax margin – -58.5% 15.7%
Net margin – -58.2% 15.6%
FCF margin – -57.0% -47.4%
Operating cash flow margin – -50.1% -46.6%
Return on equity -60.1% -28.5% 38.3%
Return on assets -53.1% -23.1% 12.8%
Return on invested capital – – 21.1%
Return on capital employed -59.2% -27.2% 21.0%
Asset turnover – 0.4x 0.8x
Cash conversion (OCF / net income) 0.9x 0.9x -3.0x
Stock comp / revenue – 12.3% 8.0%

Financial Health

11 metrics
MetricSLDBIOVAPGEN
Debt / assets – – 44.4%
Debt / equity – – 1.1x
Net debt / EBITDA – – 1.2x
Debt / FCF – – -1.3x
Liabilities / assets 12.3% 18.0% 60.5%
Equity / assets 87.7% 82.0% 39.5%
Interest coverage – – 2.8x
Current ratio 12.0x 5.2x 5.6x
Quick ratio 11.5x 4.6x 4.6x
Cash ratio 11.5x 3.6x 1.5x
Altman Z-score – 8.06 -6.00

Shareholder Returns

7 metrics
MetricSLDBIOVAPGEN
Dividend yield – – –
Net buyback yield -25.9% -8.2% -0.2%
Shareholder yield -25.9% -8.2% -0.2%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSLDBIOVAPGEN
Forward P/E – – 24.8xFY2026
EPS, next fiscal year $-1.63FY2026 $-0.47FY2026 $0.17FY2026
EPS growth, the year after – – +288.2%
Revenue, next fiscal year $0.00FY2026 $435.90MFY2026 $249.16MFY2026
Revenue growth, next FY – +65.4%FY2026 +2,474.0%FY2026
Revenue growth, the year after – +33.1% +82.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSLDBIOVAPGEN
Held by institutions 79.7% 63.3% 39.2%
Institutions holding 157 292 211
Change in shares held, QoQ +18.9% +6.5% +4.9%
Institutions buying 101 174 123
Institutions selling 37 66 46
Buyers to sellers 2.73 2.64 2.67

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SLDBIOVAPGEN
SLDB 1.00 0.26 0.31
IOVA 0.26 1.00 0.23
PGEN 0.31 0.23 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, SLDB, IOVA and PGEN?

Iovance Biotherapeutics (IOVA) is the largest by market capitalisation: Solid Biosciences (SLDB) $1.00B, Iovance Biotherapeutics (IOVA) $3.66B, Precigen (PGEN) $1.57B.

Which company is growing faster?

Precigen (PGEN) grew revenue fastest over the trailing twelve months: Iovance Biotherapeutics (IOVA) +51.3%, Precigen (PGEN) +2,387.6%.

Which company is more profitable?

Precigen (PGEN) has the highest net margin (Iovance Biotherapeutics (IOVA) -58.2%, Precigen (PGEN) 15.6%).

Which stock has performed better?

Over the past year Iovance Biotherapeutics (IOVA) returned the most: Solid Biosciences (SLDB) +56.7%, Iovance Biotherapeutics (IOVA) +327.6%, Precigen (PGEN) +5.8%. Over five years, Precigen (PGEN) compounded fastest (Solid Biosciences (SLDB) -29.5%/yr, Iovance Biotherapeutics (IOVA) -20.9%/yr, Precigen (PGEN) -3.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Solid Biosciences (SLDB) has been the steadiest (Solid Biosciences (SLDB) 75.9%, Iovance Biotherapeutics (IOVA) 109.9%, Precigen (PGEN) 85.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SLDB, IOVA and PGEN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Precigen (PGEN) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.