SLBT vs SRPT vs NTLA Stock Comparison

SL Science Holding, Sarepta Therapeutics and Intellia Therapeutics Prices as of Oct 29, 2026 Peers: Industry group
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SLBT SL Science Holding Ltd
$1.17 -36.1% 1M -88.7% 1Y
Market cap
$2.82B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
1 win

Head to Head

7 decided of 12

Intellia Therapeutics leads on 3 of the 12 questions below (Intellia Therapeutics 3, Sarepta Therapeutics 3, SL Science Holding 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSLBTSRPTNTLALeader
Larger companyMarket capitalisation $2.82B $1.96B $1.65B SLBT
Cheaper on earningsLower P/E, profitable companies only — -16.8x -4.1x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 6.7x — –
Faster revenue growthRevenue growth, trailing twelve months — -20.4% +12.6% NTLA
More profitableNet margin, trailing twelve months — -5.9% -672.2% SRPT
Better return on capitalReturn on invested capital — -6.1% — –
Less leveragedLower net debt / EBITDA — -0.6x — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -88.7% -18.0% +0.8% NTLA
Better 5-year returnAnnualised price return, 5 years — -24.7%/yr -37.0%/yr SRPT
Less volatileAnnualised volatility, 1 year 175.5% 81.1% 79.8% NTLA
Higher overall scoreMean of the five percentile scores vs peers — 67/100 50/100 SRPT

Percentile Scorecard

SLBTSRPTNTLA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSLBTSRPTNTLA
Valuation 11 #556 of 624 97 #23 of 624 35 #404 of 624
Growth – 64 #220 of 601 63 #221 of 601
Profitability – 80 #111 of 541 39 #331 of 541
Financial Health 58 #271 of 647 34 #430 of 647 72 #181 of 647
Shareholder Returns – 61 #141 of 359 40 #216 of 359
Overall – 67 50
  • SLBT ranked among 671 companies in Pharmaceuticals and Biotechnology
  • SRPT ranked among 671 companies in Pharmaceuticals and Biotechnology
  • NTLA ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSLBTSRPTNTLASPY
1 month -36.1%+3.2%+10.0% +0.7%
3 months -56.5%+23.6%+19.3% +3.7%
6 months -87.4%-7.9%-1.9% +7.1%
Year to date -88.9%-10.6%+47.2% +12.8%
1 year -88.7%-18.0%+0.8% +11.9%
3 years —-82.1%-44.5% +85.2%
3 years, per year —-43.7%-17.8% +22.8%
5 years —-75.7%-90.1% +67.6%
5 years, per year —-24.7%-37.0% +10.9%
10 years —-53.0%+2.1% +262.0%
10 years, per year —-7.3%+0.2% +13.7%

Risk

MeasureSLBTSRPTNTLASPY
Volatility, 1Y 175.5%81.1%79.8% 12.7%
Downside volatility, 1Y 170.0%85.8%81.7% 12.6%
Beta vs S&P 500, 1Y 0.242.082.46 1.00
Return / volatility, 1Y -0.51-0.220.01 0.94
Max drawdown, 5Y -91.0%-92.7%-95.5% -25.4%
From 52-week high -90.9%-21.3%-25.8% -1.2%
52-week high $12.81$24.45$17.84 $779.14
52-week low $1.15$14.86$8.04 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSLBTSRPTNTLA
P/E now vs peer median —median 17.8x -17.4xmedian 17.8x -4.4xmedian 17.8x
P/S now vs peer median —median 9.1x 1.0xmedian 9.1x 31.1xmedian 9.1x
EV/EBITDA now vs peer median —median 15.0x -21.2xmedian 15.0x -3.4xmedian 15.0x
P/FCF now vs peer median -1,359xmedian 21.7x 24.8xmedian 21.7x -5.3xmedian 21.7x
P/B now vs peer median 365.9xmedian 2.2x 1.3xmedian 2.2x 2.5xmedian 2.2x
PEG now vs peer median —median 0.35 -0.33median 0.35 -0.27median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSLBTSRPTNTLA
Revenue – $1.97B $59.51M
Gross profit – $1.17B –
Operating income – -$143.25M -$423.48M
Net income – -$136.73M -$399.98M
Free cash flow – $81.85M -$348.69M
R&D – $789.44M $346.73M
EPS (diluted) – $-1.11 $-3.00
Cash & equivalents $8.31M $571.15M $106.13M
Total debt – $847.62M –
Shares (diluted) – 105.43M 133.48M
Enterprise value $2.80B -$1.27B -$126.19M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSLBTSRPTNTLA
P/E – -17.4x -4.4x
P/FCF -1,359x 24.8x -5.3x
P/Operating cash flow – 18.3x -5.3x
P/S – 1.0x 31.1x
P/B 365.9x 1.3x 2.5x
P/Tangible book 365.9x 1.4x 2.5x
EV/EBITDA – -21.2x -3.4x
EV/EBIT – -14.6x -3.3x
EV/Revenue – 1.1x 23.8x
EV/FCF – 25.5x -4.1x
EV/Operating cash flow – 18.8x -4.1x
PEG (3Y EPS CAGR) – -0.33 -0.27

Growth

14 metrics
MetricSLBTSRPTNTLA
Revenue growth (1Y) – -20.4% 12.6%
Revenue CAGR (3Y) – 25.3% 3.9%
Gross profit growth (1Y) – -40.7% –
Gross profit CAGR (3Y) – 10.6% –
Operating income growth (1Y) – -15,270% 17.3%
Operating income CAGR (3Y) – 34.5% 2.7%
Net income growth (1Y) – -135.9% 16.7%
Net income CAGR (3Y) – 46.8% 4.1%
EPS growth (1Y) – -215.7% 35.3%
EPS CAGR (3Y) – 52.3% 16.5%
Operating cash flow growth (1Y) – 136.9% 17.2%
Operating cash flow CAGR (3Y) – 30.6% 2.0%
Free cash flow growth (1Y) – 118.1% 17.3%
Free cash flow CAGR (3Y) – 29.1% 3.2%

Profitability

14 metrics
MetricSLBTSRPTNTLA
Gross margin – 59.1% –
EBITDA margin – -5.0% -696.4%
Operating margin – -7.3% -711.7%
Pretax margin – -6.6% -671.0%
Net margin – -5.9% -672.2%
FCF margin – 4.1% -586.0%
Operating cash flow margin – 5.6% -582.5%
Return on equity – -9.0% -59.2%
Return on assets – -4.3% -49.4%
Return on invested capital – -6.1% –
Return on capital employed – -5.3% -58.1%
Asset turnover – 0.6x 0.1x
Cash conversion (OCF / net income) – -0.8x 0.9x
Stock comp / revenue – 6.3% 114.1%

Financial Health

11 metrics
MetricSLBTSRPTNTLA
Debt / assets – 26.6% –
Debt / equity – 0.6x –
Net debt / EBITDA – -0.6x –
Debt / FCF – 10.4x –
Liabilities / assets 21.8% 52.1% 15.1%
Equity / assets 78.2% 47.9% 84.9%
Interest coverage – – –
Current ratio 4.4x 4.4x 6.6x
Quick ratio 4.3x 2.4x 5.6x
Cash ratio 4.3x 1.6x 5.5x
Altman Z-score – -0.15 3.09

Shareholder Returns

7 metrics
MetricSLBTSRPTNTLA
Dividend yield – – –
Net buyback yield – -1.1% -7.1%
Shareholder yield 0.0% -1.1% -7.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSLBTSRPTNTLA
Forward P/E – 6.7xFY2026 –
EPS, next fiscal year – $2.88FY2026 $-3.38FY2026
EPS growth, the year after – -88.5% –
Revenue, next fiscal year – $1.76BFY2026 $48.94MFY2026
Revenue growth, next FY – -20.1%FY2026 -27.7%FY2026
Revenue growth, the year after – -21.5% +158.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSLBTSRPTNTLA
Held by institutions – 100.0% 100.0%
Institutions holding – 325 329
Change in shares held, QoQ – +4.5% +30.5%
Institutions buying – 148 195
Institutions selling – 116 78
Buyers to sellers – 1.28 2.50

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SLBTSRPTNTLA
SLBT 1.00 0.00 -0.09
SRPT 0.00 1.00 0.33
NTLA -0.09 0.33 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, SLBT, SRPT and NTLA?

SL Science Holding (SLBT) is the largest by market capitalisation: SL Science Holding (SLBT) $2.82B, Sarepta Therapeutics (SRPT) $1.96B, Intellia Therapeutics (NTLA) $1.65B.

Which company is growing faster?

Intellia Therapeutics (NTLA) grew revenue fastest over the trailing twelve months: Sarepta Therapeutics (SRPT) -20.4%, Intellia Therapeutics (NTLA) +12.6%.

Which company is more profitable?

Sarepta Therapeutics (SRPT) has the highest net margin (Sarepta Therapeutics (SRPT) -5.9%, Intellia Therapeutics (NTLA) -672.2%).

Which stock has performed better?

Over the past year Intellia Therapeutics (NTLA) returned the most: SL Science Holding (SLBT) -88.7%, Sarepta Therapeutics (SRPT) -18.0%, Intellia Therapeutics (NTLA) +0.8%. Over five years, Sarepta Therapeutics (SRPT) compounded fastest (Sarepta Therapeutics (SRPT) -24.7%/yr, Intellia Therapeutics (NTLA) -37.0%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Intellia Therapeutics (NTLA) has been the steadiest (SL Science Holding (SLBT) 175.5%, Sarepta Therapeutics (SRPT) 81.1%, Intellia Therapeutics (NTLA) 79.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SLBT, SRPT and NTLA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Intellia Therapeutics (NTLA) leads on 3. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.