RGEN vs TMO vs TXG Stock Comparison

Repligen, Thermo Fisher Scientific and 10x Genomics Prices as of Oct 27, 2026 Peers: Industry group
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RGEN Repligen Corp
$175.80 -7.3% 1M +9.1% 1Y
Market cap
$10.40B
P/E
–
Revenue (TTM)
$805.61M
Div. yield
–
Life Sciences Tools Healthcare
1 win
TXG 10x Genomics, Inc.
$78.02 -9.0% 1M +474.1% 1Y
Market cap
$11.00B
P/E
–
Revenue (TTM)
$616.91M
Div. yield
–
Life Sciences Tools Healthcare
2 wins

Head to Head

7 decided of 12

Thermo Fisher Scientific leads on 4 of the 12 questions below (Thermo Fisher Scientific 4, 10x Genomics 2, Repligen 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionRGENTMOTXGLeader
Larger companyMarket capitalisation $10.40B $260.40B $11.00B TMO
Cheaper on earningsLower P/E, profitable companies only -881.4x 36.8x -146.4x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 90.6x 26.8x — TMO
Faster revenue growthRevenue growth, trailing twelve months +13.8% +8.3% -4.3% RGEN
More profitableNet margin, trailing twelve months — — -12.2% –
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +9.1% +23.0% +474.1% TXG
Better 5-year returnAnnualised price return, 5 years -9.5%/yr +2.3%/yr -13.9%/yr TMO
Less volatileAnnualised volatility, 1 year 46.3% 29.8% 73.9% TMO
Higher overall scoreMean of the five percentile scores vs peers 56/100 51/100 61/100 TXG

Percentile Scorecard

RGENTMOTXG

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisRGENTMOTXG
Valuation 43 #129 of 227 50 #113 of 227 43 #130 of 227
Growth 31 #152 of 219 41 #130 of 219 66 #76 of 219
Profitability 68 #66 of 206 70 #63 of 206 63 #77 of 206
Financial Health 83 #41 of 238 – 68 #78 of 238
Shareholder Returns – 44 #76 of 134 68 #44 of 134
Overall 56 51 61
  • RGEN ranked among 247 companies in Medical Devices and Diagnostics
  • TMO ranked among 247 companies in Medical Devices and Diagnostics
  • TXG ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodRGENTMOTXGSPY
1 month -7.3%+2.9%-9.0% -0.2%
3 months +21.0%+20.3%+65.8% +3.9%
6 months +49.7%+47.4%+265.1% +8.2%
Year to date +7.3%+19.7%+378.4% +12.9%
1 year +9.1%+23.0%+474.1% +12.3%
3 years +47.0%+60.7%+114.3% +87.4%
3 years, per year +13.7%+17.1%+28.9% +23.3%
5 years -39.4%+11.8%-52.6% +67.9%
5 years, per year -9.5%+2.3%-13.9% +10.9%
10 years +513.8%+364.6%— +261.1%
10 years, per year +19.9%+16.6%— +13.7%

Risk

MeasureRGENTMOTXGSPY
Volatility, 1Y 46.3%29.8%73.9% 12.7%
Downside volatility, 1Y 46.8%28.3%66.1% 12.7%
Beta vs S&P 500, 1Y 1.210.622.22 1.00
Return / volatility, 1Y 0.200.776.41 0.97
Max drawdown, 5Y -66.2%-41.5%-96.1% -25.4%
From 52-week high -9.6%-0.5%-20.2% -1.2%
52-week high $194.57$696.55$97.74 $779.14
52-week low $102.87$438.34$12.44 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleRGENTMOTXG
P/E now vs peer median -840.2xmedian 29.6x 36.4xmedian 29.6x -135.0xmedian 29.6x
P/S now vs peer median 12.3xmedian 2.9x 5.4xmedian 2.9x 16.5xmedian 2.9x
EV/EBITDA now vs peer median —median 17.4x —median 17.4x -227.8xmedian 17.4x
P/FCF now vs peer median 98.1xmedian 22.3x 34.0xmedian 22.3x 83.7xmedian 22.3x
P/B now vs peer median 4.7xmedian 2.3x 4.7xmedian 2.3x 12.3xmedian 2.3x
PEG now vs peer median 29.56median 1.04 4.80median 1.04 -5.03median 1.04

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsRGENTMOTXG
Revenue $805.61M $47.35B $616.91M
Gross profit – – $432.03M
Operating income $18.24M $8.47B -$88.38M
Net income $26.59M $7.09B -$75.13M
Free cash flow – – $121.44M
R&D $56.43M $1.40B $226.80M
EPS (diluted) $-0.21 $19.06 $-0.58
Cash & equivalents $726.96M $5.46B –
Shares (diluted) 56.64M 371.00M 129.98M
Enterprise value $10.40B $260.40B $10.80B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricRGENTMOTXG
P/E -840.2x 36.4x -135.0x
P/FCF 98.1x 34.0x 83.7x
P/Operating cash flow 76.4x 27.5x 80.0x
P/S 12.3x 5.4x 16.5x
P/B 4.7x 4.7x 12.3x
P/Tangible book 5.6x 7.0x 13.3x
EV/EBITDA – – -227.8x
EV/EBIT – – -114.4x
EV/Revenue 12.3x 5.4x 16.4x
EV/FCF – – 83.3x
EV/Operating cash flow 76.4x 27.5x 79.6x
PEG (3Y EPS CAGR) 29.56 4.80 -5.03

Growth

14 metrics
MetricRGENTMOTXG
Revenue growth (1Y) 13.8% 8.3% -4.3%
Revenue CAGR (3Y) 7.3% 2.9% 2.8%
Gross profit growth (1Y) – – -3.5%
Gross profit CAGR (3Y) – – 1.1%
Operating income growth (1Y) 2,185% 12.8% 12.1%
Operating income CAGR (3Y) -40.5% 7.2% 20.9%
Net income growth (1Y) 1,430% 7.9% 11.2%
Net income CAGR (3Y) -35.9% 6.2% 24.2%
EPS growth (1Y) -777.9% 9.7% 14.9%
EPS CAGR (3Y) -28.4% 7.6% 26.8%
Operating cash flow growth (1Y) -0.8% 21.9% 89.8%
Operating cash flow CAGR (3Y) -4.0% 4.5% 135.5%
Free cash flow growth (1Y) – – 113.5%
Free cash flow CAGR (3Y) – – 44.7%

Profitability

14 metrics
MetricRGENTMOTXG
Gross margin – – 70.0%
EBITDA margin – – -7.2%
Operating margin – – -14.3%
Pretax margin – – -12.1%
Net margin – – -12.2%
FCF margin – – 19.7%
Operating cash flow margin 16.1% 19.7% 20.6%
Return on equity 1.3% 13.2% -9.2%
Return on assets 0.9% 6.2% -7.3%
Return on invested capital – – –
Return on capital employed – – -9.8%
Asset turnover 0.3x 0.4x 0.6x
Cash conversion (OCF / net income) 4.9x 1.3x -1.7x
Stock comp / revenue 4.2% – 16.0%

Financial Health

11 metrics
MetricRGENTMOTXG
Debt / assets – – –
Debt / equity – – –
Net debt / EBITDA – – –
Debt / FCF – – –
Liabilities / assets 28.5% – 19.9%
Equity / assets 71.5% 47.9% 80.1%
Interest coverage – – –
Current ratio 9.9x 1.8x 5.7x
Quick ratio – – 0.8x
Cash ratio – – 0.4x
Altman Z-score – – 28.69

Shareholder Returns

7 metrics
MetricRGENTMOTXG
Dividend yield – 0.3% –
Net buyback yield – – -0.1%
Shareholder yield – 0.3% -0.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusRGENTMOTXG
Forward P/E 90.6xFY2026 26.8xFY2026 –
EPS, next fiscal year $1.94FY2026 $25.91FY2026 $-0.79FY2026
EPS growth, next FY +13.5%FY2026 +13.3%FY2026 –
EPS growth, the year after +29.4% +2.0% –
Revenue, next fiscal year $773.94MFY2026 $50.12BFY2026 $580.42MFY2026
Revenue growth, next FY +4.8%FY2026 +12.5%FY2026 -9.7%FY2026
Revenue growth, the year after +35.9% -2.8% +24.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersRGENTMOTXG
Held by institutions 100.0% 90.2% 100.0%
Institutions holding 482 2,622 389
Change in shares held, QoQ +1.2% +0.8% +2.4%
Institutions buying 272 1,142 197
Institutions selling 141 1,144 137
Buyers to sellers 1.93 1.00 1.44

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

RGENTMOTXG
RGEN 1.00 0.66 0.48
TMO 0.66 1.00 0.50
TXG 0.48 0.50 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, RGEN, TMO and TXG?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: Repligen (RGEN) $10.40B, Thermo Fisher Scientific (TMO) $260.40B, 10x Genomics (TXG) $11.00B.

Which company is growing faster?

Repligen (RGEN) grew revenue fastest over the trailing twelve months: Repligen (RGEN) +13.8%, Thermo Fisher Scientific (TMO) +8.3%, 10x Genomics (TXG) -4.3%.

Which stock has performed better?

Over the past year 10x Genomics (TXG) returned the most: Repligen (RGEN) +9.1%, Thermo Fisher Scientific (TMO) +23.0%, 10x Genomics (TXG) +474.1%. Over five years, Thermo Fisher Scientific (TMO) compounded fastest (Repligen (RGEN) -9.5%/yr, Thermo Fisher Scientific (TMO) +2.3%/yr, 10x Genomics (TXG) -13.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Thermo Fisher Scientific (TMO) has been the steadiest (Repligen (RGEN) 46.3%, Thermo Fisher Scientific (TMO) 29.8%, 10x Genomics (TXG) 73.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, RGEN, TMO and TXG?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Thermo Fisher Scientific (TMO) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.