RGEN vs TMO vs ILMN Stock Comparison

Repligen, Thermo Fisher Scientific and Illumina Prices as of Nov 4, 2026 Peers: Industry group
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RGEN Repligen Corp
$178.20 -6.0% 1M +21.3% 1Y
Market cap
$10.10B
P/E
–
Revenue (TTM)
$805.61M
Div. yield
–
Life Sciences Tools Healthcare
2 wins
ILMN Illumina, Inc.
$226.54 -22.9% 1M +93.9% 1Y
Market cap
$34.25B
P/E
38.2x
Revenue (TTM)
$4.54B
Div. yield
–
Life Sciences Tools Healthcare
4 wins

Head to Head

11 decided of 12

Thermo Fisher Scientific leads on 5 of the 12 questions below (Thermo Fisher Scientific 5, Illumina 4, Repligen 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionRGENTMOILMNLeader
Larger companyMarket capitalisation $10.10B $261.60B $34.25B TMO
Cheaper on earningsLower P/E, profitable companies only -851.7x 37.0x 38.2x TMO
Cheaper on forward earningsLower price / next fiscal year consensus EPS 91.9x 27.2x 45.4x TMO
Faster revenue growthRevenue growth, trailing twelve months +13.8% +8.3% +5.8% RGEN
More profitableNet margin, trailing twelve months -1.5% 14.9% 19.7% ILMN
Better return on capitalReturn on invested capital 0.0% 8.0% 16.6% ILMN
Less leveragedLower net debt / EBITDA -2.8x 3.1x 0.4x RGEN
Higher dividend yieldTrailing dividend yield — 0.26% — –
Better 1-year returnPrice return, last 12 months +21.3% +24.9% +93.9% ILMN
Better 5-year returnAnnualised price return, 5 years -7.8%/yr +2.7%/yr -10.6%/yr TMO
Less volatileAnnualised volatility, 1 year 46.5% 30.0% 50.2% TMO
Higher overall scoreMean of the five percentile scores vs peers 56/100 59/100 76/100 ILMN

Percentile Scorecard

RGENTMOILMN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisRGENTMOILMN
Valuation 53 #109 of 229 61 #90 of 229 59 #94 of 229
Growth 25 #167 of 221 39 #136 of 221 75 #56 of 221
Profitability 66 #71 of 209 81 #40 of 209 99 #4 of 209
Financial Health 82 #45 of 240 31 #166 of 240 61 #94 of 240
Shareholder Returns 55 #67 of 146 82 #27 of 146 84 #24 of 146
Overall 56 59 76
  • RGEN ranked among 248 companies in Medical Devices and Diagnostics
  • TMO ranked among 248 companies in Medical Devices and Diagnostics
  • ILMN ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodRGENTMOILMNSPY
1 month -6.0%+4.4%-22.9% -1.0%
3 months +12.4%+22.3%+13.3% -0.4%
6 months +41.7%+49.3%+58.9% +4.5%
Year to date +8.8%+21.8%+72.7% +12.4%
1 year +21.3%+24.9%+93.9% +13.6%
3 years +18.5%+55.3%+99.2% +76.4%
3 years, per year +5.8%+15.8%+25.8% +20.8%
5 years -33.2%+14.5%-42.9% +63.7%
5 years, per year -7.8%+2.7%-10.6% +10.4%
10 years +558.3%+381.7%+73.0% +267.7%
10 years, per year +20.7%+17.0%+5.6% +13.9%

Risk

MeasureRGENTMOILMNSPY
Volatility, 1Y 46.5%30.0%50.2% 12.8%
Downside volatility, 1Y 46.8%28.6%49.5% 12.7%
Beta vs S&P 500, 1Y 1.230.640.99 1.00
Return / volatility, 1Y 0.460.831.87 1.06
Max drawdown, 5Y -64.7%-41.5%-82.9% -25.4%
From 52-week high -8.4%-0.5%-22.9% -1.6%
52-week high $194.57$709.29$293.69 $779.14
52-week low $102.87$438.34$114.44 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleRGENTMOILMN
P/E now vs peer median -851.7xmedian 28.5x 37.0xmedian 28.5x 38.2xmedian 28.5x
P/S now vs peer median 12.5xmedian 2.9x 5.5xmedian 2.9x 7.5xmedian 2.9x
EV/EBITDA now vs peer median 89.3xmedian 18.5x 25.7xmedian 18.5x 28.1xmedian 18.5x
P/FCF now vs peer median 94.7xmedian 26.7x 34.4xmedian 26.7x 32.4xmedian 26.7x
P/B now vs peer median 4.8xmedian 2.3x 4.8xmedian 2.3x 10.9xmedian 2.3x
PEG now vs peer median 29.96median 0.93 4.89median 0.93 0.93median 0.93

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsRGENTMOILMN
Revenue $805.61M $47.35B $4.54B
Gross profit $430.67M $19.45B $3.08B
Operating income $18.24M $8.47B $960.00M
Net income -$11.80M $7.09B $895.00M
Free cash flow $106.72M $7.60B $1.06B
R&D $57.23M $1.40B $975.00M
EPS (diluted) $-0.21 $19.06 $5.85
Cash & equivalents $726.96M $5.46B $1.29B
Total debt $555.60M $41.37B $1.79B
Shares (diluted) 56.64M 371.00M 153.00M
Enterprise value $6.88B $238.24B $28.96B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricRGENTMOILMN
P/E -851.7x 37.0x 38.2x
P/FCF 94.7x 34.4x 32.4x
P/Operating cash flow 77.8x 28.1x 27.8x
P/S 12.5x 5.5x 7.5x
P/B 4.8x 4.8x 10.9x
P/Tangible book 5.7x 7.1x 12.4x
EV/EBITDA 89.3x 25.7x 28.1x
EV/EBIT 537.1x 35.1x 36.2x
EV/Revenue 12.2x 6.3x 7.6x
EV/FCF 91.8x 39.1x 32.8x
EV/Operating cash flow 75.4x 31.8x 28.2x
PEG (3Y EPS CAGR) 29.96 4.89 0.93

Growth

14 metrics
MetricRGENTMOILMN
Revenue growth (1Y) 13.8% 8.3% 5.8%
Revenue CAGR (3Y) 7.3% 2.9% -0.7%
Gross profit growth (1Y) 33.0% 7.8% 8.5%
Gross profit CAGR (3Y) 13.3% 4.0% 4.4%
Operating income growth (1Y) 2,185% 12.8% 23.1%
Operating income CAGR (3Y) -40.5% 7.2% 30.0%
Net income growth (1Y) -779.2% 7.9% 27.5%
Net income CAGR (3Y) -28.4% 6.2% 40.9%
EPS growth (1Y) -777.9% 9.7% 28.3%
EPS CAGR (3Y) -28.4% 7.6% 41.3%
Operating cash flow growth (1Y) -0.8% 21.9% 9.6%
Operating cash flow CAGR (3Y) -4.0% 4.5% 47.5%
Free cash flow growth (1Y) -3.0% 24.3% 5.7%
Free cash flow CAGR (3Y) 1.8% 5.1% 126.5%

Profitability

14 metrics
MetricRGENTMOILMN
Gross margin 53.5% 41.1% 67.9%
EBITDA margin 13.6% 24.4% 27.3%
Operating margin 2.3% 17.9% 21.2%
Pretax margin 1.0% 16.7% 23.3%
Net margin -1.5% 14.9% 19.7%
FCF margin 13.2% 16.0% 23.3%
Operating cash flow margin 16.1% 19.7% 27.1%
Return on equity -0.6% 13.2% 29.9%
Return on assets -0.4% 6.2% 13.3%
Return on invested capital 0.0% 8.0% 16.6%
Return on capital employed 0.6% 8.5% 17.2%
Asset turnover 0.3x 0.4x 0.7x
Cash conversion (OCF / net income) -11.0x 1.3x 1.4x
Stock comp / revenue 4.2% 0.7% 5.9%

Financial Health

11 metrics
MetricRGENTMOILMN
Debt / assets 19.0% 36.2% 26.3%
Debt / equity 0.3x 0.8x 0.6x
Net debt / EBITDA -2.8x 3.1x 0.4x
Debt / FCF 5.2x 5.4x 1.7x
Liabilities / assets 28.5% 52.1% 53.8%
Equity / assets 71.5% 47.9% 46.2%
Interest coverage 0.8x 5.5x 9.8x
Current ratio 9.9x 1.8x 2.6x
Quick ratio 8.1x 1.2x 1.8x
Cash ratio 6.9x 0.4x 1.2x
Altman Z-score 8.22 4.20 7.10

Shareholder Returns

7 metrics
MetricRGENTMOILMN
Dividend yield – 0.3% –
Net buyback yield -0.2% 1.5% 1.1%
Shareholder yield -0.2% 1.8% 1.1%
Payout ratio (earnings) – 9.5% –
Payout ratio (FCF) – 8.9% –
Dividend growth (1Y) – 8.0% –
Dividend CAGR (3Y) – 10.1% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusRGENTMOILMN
Forward P/E 91.9xFY2026 27.2xFY2026 45.4xFY2026
EPS, next fiscal year $1.94FY2026 $25.91FY2026 $4.99FY2026
EPS growth, next FY +13.5%FY2026 +13.3%FY2026 +3.1%FY2026
EPS growth, the year after +29.4% +2.0% +25.7%
Revenue, next fiscal year $773.94MFY2026 $50.12BFY2026 $4.52BFY2026
Revenue growth, next FY +4.8%FY2026 +12.5%FY2026 +4.1%FY2026
Revenue growth, the year after +35.9% -2.8% +12.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersRGENTMOILMN
Held by institutions 100.0% 90.2% 100.0%
Institutions holding 483 2,627 935
Change in shares held, QoQ +1.2% +0.8% +0.0%
Institutions buying 273 1,145 464
Institutions selling 141 1,145 331
Buyers to sellers 1.94 1.00 1.40

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

RGENTMOILMN
RGEN 1.00 0.67 0.45
TMO 0.67 1.00 0.51
ILMN 0.45 0.51 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, RGEN, TMO and ILMN?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: Repligen (RGEN) $10.10B, Thermo Fisher Scientific (TMO) $261.60B, Illumina (ILMN) $34.25B.

Which stock is cheaper, RGEN, TMO and ILMN?

Thermo Fisher Scientific (TMO) trades on the lowest price-to-earnings ratio (Repligen (RGEN) -851.7x, Thermo Fisher Scientific (TMO) 37.0x, Illumina (ILMN) 38.2x). On next year's consensus earnings, Thermo Fisher Scientific (TMO) is cheapest (Repligen (RGEN) 91.9x, Thermo Fisher Scientific (TMO) 27.2x, Illumina (ILMN) 45.4x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Repligen (RGEN) grew revenue fastest over the trailing twelve months: Repligen (RGEN) +13.8%, Thermo Fisher Scientific (TMO) +8.3%, Illumina (ILMN) +5.8%.

Which company is more profitable?

Illumina (ILMN) has the highest net margin (Repligen (RGEN) -1.5%, Thermo Fisher Scientific (TMO) 14.9%, Illumina (ILMN) 19.7%). On return on invested capital, Illumina (ILMN) leads (Repligen (RGEN) 0.0%, Thermo Fisher Scientific (TMO) 8.0%, Illumina (ILMN) 16.6%).

Which stock has performed better?

Over the past year Illumina (ILMN) returned the most: Repligen (RGEN) +21.3%, Thermo Fisher Scientific (TMO) +24.9%, Illumina (ILMN) +93.9%. Over five years, Thermo Fisher Scientific (TMO) compounded fastest (Repligen (RGEN) -7.8%/yr, Thermo Fisher Scientific (TMO) +2.7%/yr, Illumina (ILMN) -10.6%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Thermo Fisher Scientific (TMO) 0.26%. Repligen (RGEN) and Illumina (ILMN) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Thermo Fisher Scientific (TMO) has been the steadiest (Repligen (RGEN) 46.5%, Thermo Fisher Scientific (TMO) 30.0%, Illumina (ILMN) 50.2%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, RGEN, TMO and ILMN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Thermo Fisher Scientific (TMO) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.