PFE vs QGEN vs TMO Stock Comparison

Pfizer, Qiagen and Thermo Fisher Scientific Prices as of Nov 3, 2026 Peers: Industry group
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PFE Pfizer Inc
$29.98 +7.8% 1M +21.6% 1Y
Market cap
$175.10B
P/E
40.4x
Revenue (TTM)
$63.70B
Div. yield
0.06%
Pharmaceuticals Healthcare
4 wins
QGEN Qiagen N.V.
$50.38 +12.6% 1M +4.8% 1Y
Market cap
$11.03B
P/E
27.0x
Revenue (TTM)
$2.10B
Div. yield
–
Life Sciences Tools Healthcare
4 wins

Head to Head

12 decided of 12

Thermo Fisher Scientific leads on 4 of the 12 questions below (Thermo Fisher Scientific 4, Qiagen 4, Pfizer 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionPFEQGENTMOLeader
Larger companyMarket capitalisation $175.10B $11.03B $261.99B TMO
Cheaper on earningsLower P/E, profitable companies only 40.4x 27.0x 37.0x QGEN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 10.5x 21.4x 27.0x PFE
Faster revenue growthRevenue growth, trailing twelve months -0.2% +3.0% +8.3% TMO
More profitableNet margin, trailing twelve months 6.8% 19.5% 14.9% QGEN
Better return on capitalReturn on invested capital 13.4% 7.9% 8.0% PFE
Less leveragedLower net debt / EBITDA 1.9x 1.3x 3.1x QGEN
Higher dividend yieldTrailing dividend yield 0.06% 0.00% 0.00% PFE
Better 1-year returnPrice return, last 12 months +21.6% +4.8% +23.6% TMO
Better 5-year returnAnnualised price return, 5 years -7.3%/yr -4.1%/yr +1.8%/yr TMO
Less volatileAnnualised volatility, 1 year 21.8% 35.6% 30.0% PFE
Higher overall scoreMean of the five percentile scores vs peers 65/100 71/100 59/100 QGEN

Percentile Scorecard

PFEQGENTMO

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisPFEQGENTMO
Valuation 94 #37 of 634 74 #61 of 229 60 #92 of 229
Growth 23 #469 of 607 30 #156 of 221 39 #135 of 221
Profitability 92 #47 of 557 93 #16 of 209 82 #39 of 209
Financial Health 25 #493 of 654 64 #86 of 240 31 #166 of 240
Shareholder Returns 89 #44 of 401 93 #12 of 147 82 #28 of 147
Overall 65 71 59
  • PFE ranked among 671 companies in Pharmaceuticals and Biotechnology
  • QGEN ranked among 248 companies in Medical Devices and Diagnostics
  • TMO ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodPFEQGENTMOSPY
1 month +7.8%+12.6%+6.6% -2.0%
3 months +18.0%+19.0%+23.8% -2.2%
6 months +13.3%+48.2%+49.6% +4.2%
Year to date +20.4%+6.4%+20.5% +10.6%
1 year +21.6%+4.8%+23.6% +10.4%
3 years -4.1%+15.1%+53.6% +73.6%
3 years, per year -1.4%+4.8%+15.4% +20.2%
5 years -31.6%-18.9%+9.2% +61.6%
5 years, per year -7.3%-4.1%+1.8% +10.1%
10 years +0.3%+65.5%+378.1% +261.3%
10 years, per year +0.0%+5.2%+16.9% +13.7%

Risk

MeasurePFEQGENTMOSPY
Volatility, 1Y 21.8%35.6%30.0% 12.8%
Downside volatility, 1Y 21.3%30.3%28.6% 12.8%
Beta vs S&P 500, 1Y 0.200.450.64 1.00
Return / volatility, 1Y 0.990.130.79 0.81
Max drawdown, 5Y -64.8%-48.2%-41.5% -25.4%
From 52-week high -2.4%-9.5%-1.5% -3.2%
52-week high $30.71$55.66$709.29 $779.14
52-week low $23.67$32.63$438.34 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultiplePFEQGENTMO
P/E now vs peer median 39.4xmedian 18.4x 26.7xmedian 28.1x 36.6xmedian 28.1x
P/S now vs peer median 2.7xmedian 9.0x 5.2xmedian 2.9x 5.5xmedian 2.9x
EV/EBITDA now vs peer median 8.2xmedian 16.0x 18.1xmedian 18.0x 25.4xmedian 18.0x
P/FCF now vs peer median 15.6xmedian 21.8x 11.0xmedian 24.8x 34.1xmedian 24.8x
P/B now vs peer median 2.0xmedian 2.1x 3.3xmedian 2.3x 4.7xmedian 2.3x
PEG now vs peer median -0.95median 0.37 6.55median 0.95 4.84median 0.95

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsPFEQGENTMO
Revenue $63.70B $2.10B $47.35B
Gross profit $46.61B $1.31B $19.45B
Operating income $20.39B $445.43M $8.47B
Net income $4.36B $409.32M $7.09B
Free cash flow $10.99B $991.33M $7.60B
R&D $11.05B $194.67M $1.40B
EPS (diluted) $0.76 $1.87 $19.06
Cash & equivalents $976.00M $768.50M $5.46B
Total debt $63.19B $1.64B $41.37B
Shares (diluted) 5.70B 218.88M 371.00M
Enterprise value $121.75B $6.80B $238.50B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricPFEQGENTMO
P/E 39.4x 26.7x 36.6x
P/FCF 15.6x 11.0x 34.1x
P/Operating cash flow 12.8x 16.7x 27.8x
P/S 2.7x 5.2x 5.5x
P/B 2.0x 3.3x 4.7x
P/Tangible book 4.4x 3.6x 7.1x
EV/EBITDA 8.2x 18.1x 25.4x
EV/EBIT 10.9x 26.4x 34.7x
EV/Revenue 3.5x 5.6x 6.2x
EV/FCF 20.2x 11.9x 38.7x
EV/Operating cash flow 16.6x 18.0x 31.5x
PEG (3Y EPS CAGR) -0.95 6.55 4.84

Growth

14 metrics
MetricPFEQGENTMO
Revenue growth (1Y) -0.2% 3.0% 8.3%
Revenue CAGR (3Y) -7.0% 2.0% 2.9%
Gross profit growth (1Y) 1.2% 1.7% 7.8%
Gross profit CAGR (3Y) -5.6% 1.3% 4.0%
Operating income growth (1Y) 1.5% -4.9% 12.8%
Operating income CAGR (3Y) -9.9% 3.3% 7.2%
Net income growth (1Y) -59.6% 143.9% 7.9%
Net income CAGR (3Y) -41.3% 6.7% 6.2%
EPS growth (1Y) -59.7% 6.6% 9.7%
EPS CAGR (3Y) -41.3% 4.1% 7.6%
Operating cash flow growth (1Y) -11.8% -3.0% 21.9%
Operating cash flow CAGR (3Y) -2.7% 8.0% 4.5%
Free cash flow growth (1Y) -11.7% 2.3% 24.3%
Free cash flow CAGR (3Y) 1.0% 10.5% 5.1%

Profitability

14 metrics
MetricPFEQGENTMO
Gross margin 73.2% 62.2% 41.1%
EBITDA margin 42.4% 31.0% 24.4%
Operating margin 32.0% 21.2% 17.9%
Pretax margin 6.6% 22.0% 16.7%
Net margin 6.8% 19.5% 14.9%
FCF margin 17.2% 47.2% 16.0%
Operating cash flow margin 21.0% 31.2% 19.7%
Return on equity 5.0% 12.2% 13.2%
Return on assets 2.1% 7.0% 6.2%
Return on invested capital 13.4% 7.9% 8.0%
Return on capital employed 11.9% 8.5% 8.5%
Asset turnover 0.3x 0.4x 0.4x
Cash conversion (OCF / net income) 3.1x 1.6x 1.3x
Stock comp / revenue 1.5% 2.1% 0.7%

Financial Health

11 metrics
MetricPFEQGENTMO
Debt / assets 31.4% 27.9% 36.2%
Debt / equity 0.7x 0.5x 0.8x
Net debt / EBITDA 1.9x 1.3x 3.1x
Debt / FCF 5.8x 1.7x 5.4x
Liabilities / assets 57.5% 43.0% 52.1%
Equity / assets 42.5% 57.0% 47.9%
Interest coverage – 11.3x 5.5x
Current ratio 1.3x 2.8x 1.8x
Quick ratio 0.7x 2.0x 1.2x
Cash ratio 0.4x 1.4x 0.4x
Altman Z-score 2.37 4.08 4.17

Shareholder Returns

7 metrics
MetricPFEQGENTMO
Dividend yield 5.7% 5.2% 0.3%
Net buyback yield – 0.6% 1.6%
Shareholder yield 5.7% 5.8% 1.8%
Payout ratio (earnings) 224.5% – 9.5%
Payout ratio (FCF) 89.1% – 8.9%
Dividend growth (1Y) 1.5% – 8.0%
Dividend CAGR (3Y) 2.4% – 10.1%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusPFEQGENTMO
Forward P/E 10.5xFY2026 21.4xFY2026 27.0xFY2026
EPS, next fiscal year $2.85FY2026 $2.35FY2026 $25.91FY2026
EPS growth, next FY -11.5%FY2026 -1.3%FY2026 +13.3%FY2026
EPS growth, the year after -4.6% +17.4% +2.0%
Revenue, next fiscal year $60.59BFY2026 $2.25BFY2026 $50.12BFY2026
Revenue growth, next FY -3.2%FY2026 +7.8%FY2026 +12.5%FY2026
Revenue growth, the year after +3.9% -2.8% -2.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersPFEQGENTMO
Held by institutions 66.9% 67.3% 90.2%
Institutions holding 2,840 338 2,627
Change in shares held, QoQ +2.0% +16.5% +0.8%
Institutions buying 1,326 216 1,145
Institutions selling 1,205 86 1,145
Buyers to sellers 1.10 2.51 1.00

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

PFEQGENTMO
PFE 1.00 0.23 0.23
QGEN 0.23 1.00 0.45
TMO 0.23 0.45 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, PFE, QGEN and TMO?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: Pfizer (PFE) $175.10B, Qiagen (QGEN) $11.03B, Thermo Fisher Scientific (TMO) $261.99B.

Which stock is cheaper, PFE, QGEN and TMO?

Qiagen (QGEN) trades on the lowest price-to-earnings ratio (Pfizer (PFE) 40.4x, Qiagen (QGEN) 27.0x, Thermo Fisher Scientific (TMO) 37.0x). On next year's consensus earnings, Pfizer (PFE) is cheapest (Pfizer (PFE) 10.5x, Qiagen (QGEN) 21.4x, Thermo Fisher Scientific (TMO) 27.0x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Thermo Fisher Scientific (TMO) grew revenue fastest over the trailing twelve months: Pfizer (PFE) -0.2%, Qiagen (QGEN) +3.0%, Thermo Fisher Scientific (TMO) +8.3%.

Which company is more profitable?

Qiagen (QGEN) has the highest net margin (Pfizer (PFE) 6.8%, Qiagen (QGEN) 19.5%, Thermo Fisher Scientific (TMO) 14.9%). On return on invested capital, Pfizer (PFE) leads (Pfizer (PFE) 13.4%, Qiagen (QGEN) 7.9%, Thermo Fisher Scientific (TMO) 8.0%).

Which stock has performed better?

Over the past year Thermo Fisher Scientific (TMO) returned the most: Pfizer (PFE) +21.6%, Qiagen (QGEN) +4.8%, Thermo Fisher Scientific (TMO) +23.6%. Over five years, Thermo Fisher Scientific (TMO) compounded fastest (Pfizer (PFE) -7.3%/yr, Qiagen (QGEN) -4.1%/yr, Thermo Fisher Scientific (TMO) +1.8%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Pfizer (PFE) has the highest dividend yield: Pfizer (PFE) 0.06%, Qiagen (QGEN) 0.00%, Thermo Fisher Scientific (TMO) 0.00%. Qiagen (QGEN) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Pfizer (PFE) has been the steadiest (Pfizer (PFE) 21.8%, Qiagen (QGEN) 35.6%, Thermo Fisher Scientific (TMO) 30.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, PFE, QGEN and TMO?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Thermo Fisher Scientific (TMO) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.