PFE vs NVS vs MRK Stock Comparison

Pfizer, Novartis Ag and Merck Prices as of Oct 29, 2026 Peers: Industry group
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PFE Pfizer Inc
$29.95 +4.2% 1M +23.3% 1Y
Market cap
$173.68B
P/E
40.1x
Revenue (TTM)
$63.70B
Div. yield
0.06%
Pharmaceuticals Healthcare
3 wins
NVS Novartis Ag
$161.05 +10.5% 1M +32.2% 1Y
Market cap
$311.97B
P/E
17.9x
Revenue (TTM)
—
Div. yield
–
Pharmaceuticals Healthcare
2 wins
MRK Merck & Co., Inc.
$146.34 -2.0% 1M +69.0% 1Y
Market cap
$370.60B
P/E
151.1x
Revenue (TTM)
$67.38B
Div. yield
–
Pharmaceuticals Healthcare
3 wins

Head to Head

8 decided of 12

Merck leads on 3 of the 12 questions below (Merck 3, Pfizer 3, Novartis Ag 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionPFENVSMRKLeader
Larger companyMarket capitalisation $173.68B $311.97B $370.60B MRK
Cheaper on earningsLower P/E, profitable companies only 40.1x 17.9x 151.1x NVS
Cheaper on forward earningsLower price / next fiscal year consensus EPS 10.5x 17.4x 59.0x PFE
Faster revenue growthRevenue growth, trailing twelve months -0.2% — +4.9% MRK
More profitableNet margin, trailing twelve months 6.8% — — –
Better return on capitalReturn on invested capital 13.4% — — –
Less leveragedLower net debt / EBITDA 1.9x — — –
Higher dividend yieldTrailing dividend yield 0.06% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +23.3% +32.2% +69.0% MRK
Better 5-year returnAnnualised price return, 5 years -7.3%/yr +14.3%/yr +10.7%/yr NVS
Less volatileAnnualised volatility, 1 year 21.7% 27.6% 29.8% PFE
Higher overall scoreMean of the five percentile scores vs peers 65/100 — 61/100 PFE

Percentile Scorecard

PFENVSMRK

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisPFENVSMRK
Valuation 95 #34 of 624 97 #18 of 624 91 #60 of 624
Growth 24 #458 of 601 – 21 #478 of 601
Profitability 92 #45 of 541 – –
Financial Health 23 #500 of 647 – –
Shareholder Returns 92 #30 of 359 81 #68 of 359 71 #104 of 359
Overall 65 – 61
  • PFE ranked among 671 companies in Pharmaceuticals and Biotechnology
  • NVS ranked among 671 companies in Pharmaceuticals and Biotechnology
  • MRK ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodPFENVSMRKSPY
1 month +4.2%+10.5%-2.0% +0.7%
3 months +20.2%+1.7%+12.8% +3.7%
6 months +12.2%+8.9%+34.0% +7.1%
Year to date +20.3%+16.8%+39.0% +12.8%
1 year +23.3%+32.2%+69.0% +11.9%
3 years -2.0%+71.8%+42.5% +85.2%
3 years, per year -0.7%+19.8%+12.5% +22.8%
5 years -31.5%+94.6%+66.2% +67.6%
5 years, per year -7.3%+14.3%+10.7% +10.9%
10 years -6.2%+126.6%+148.7% +262.0%
10 years, per year -0.6%+8.5%+9.5% +13.7%

Risk

MeasurePFENVSMRKSPY
Volatility, 1Y 21.7%27.6%29.8% 12.7%
Downside volatility, 1Y 21.1%30.1%24.6% 12.6%
Beta vs S&P 500, 1Y 0.230.340.11 1.00
Return / volatility, 1Y 1.081.172.32 0.94
Max drawdown, 5Y -64.8%-20.4%-44.7% -25.4%
From 52-week high -1.5%-4.5%-6.5% -1.2%
52-week high $30.41$168.62$156.45 $779.14
52-week low $23.67$121.80$82.49 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultiplePFENVSMRK
P/E now vs peer median 39.4xmedian 17.8x 17.9xmedian 17.8x 147.4xmedian 17.8x
P/S now vs peer median 2.7xmedian 9.1x 5.1xmedian 9.1x 5.4xmedian 9.1x
EV/EBITDA now vs peer median 8.2xmedian 15.0x —median 15.0x —median 15.0x
P/FCF now vs peer median 15.5xmedian 21.7x 14.3xmedian 21.7x 22.9xmedian 21.7x
P/B now vs peer median 2.0xmedian 2.2x —median 2.2x —median 2.2x
PEG now vs peer median -0.95median 0.35 —median 0.35 -8.13median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsPFENVSMRK
Revenue $63.70B – $67.38B
Gross profit $46.61B – –
Operating income $20.39B – –
Net income $4.36B – –
Free cash flow $10.99B – –
R&D $11.05B – $30.76B
EPS (diluted) $0.76 – $0.99
Cash & equivalents $976.00M $400.00M –
Total debt $63.19B – –
Shares (diluted) 5.70B 1.96B 2.47B
Enterprise value $120.32B $285.20B $370.60B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricPFENVSMRK
P/E 39.4x 17.9x 147.4x
P/FCF 15.5x 14.3x 22.9x
P/Operating cash flow 12.7x – –
P/S 2.7x 5.1x 5.4x
P/B 2.0x – –
P/Tangible book 4.4x – –
EV/EBITDA 8.2x – –
EV/EBIT 10.9x – –
EV/Revenue 3.5x – 5.4x
EV/FCF 20.2x – –
EV/Operating cash flow 16.6x – –
PEG (3Y EPS CAGR) -0.95 – -8.13

Growth

14 metrics
MetricPFENVSMRK
Revenue growth (1Y) -0.2% – 4.9%
Revenue CAGR (3Y) -7.0% – 4.3%
Gross profit growth (1Y) 1.2% – –
Gross profit CAGR (3Y) -5.6% – –
Operating income growth (1Y) 1.5% – –
Operating income CAGR (3Y) -9.9% – –
Net income growth (1Y) -59.6% – –
Net income CAGR (3Y) -41.3% – –
EPS growth (1Y) -59.7% – -87.0%
EPS CAGR (3Y) -41.3% – -18.1%
Operating cash flow growth (1Y) -11.8% – –
Operating cash flow CAGR (3Y) -2.7% – –
Free cash flow growth (1Y) -11.7% – –
Free cash flow CAGR (3Y) 1.0% – –

Profitability

14 metrics
MetricPFENVSMRK
Gross margin 73.2% – –
EBITDA margin 42.4% – –
Operating margin 32.0% – –
Pretax margin 6.6% – –
Net margin 6.8% – –
FCF margin 17.2% – –
Operating cash flow margin 21.0% – –
Return on equity 5.0% – –
Return on assets 2.1% – –
Return on invested capital 13.4% – –
Return on capital employed 11.9% – –
Asset turnover 0.3x – –
Cash conversion (OCF / net income) 3.1x – –
Stock comp / revenue 1.5% – –

Financial Health

11 metrics
MetricPFENVSMRK
Debt / assets 31.4% – –
Debt / equity 0.7x – –
Net debt / EBITDA 1.9x – –
Debt / FCF 5.8x – –
Liabilities / assets 57.5% – –
Equity / assets 42.5% – –
Interest coverage – – –
Current ratio 1.3x – –
Quick ratio 0.7x – –
Cash ratio 0.4x – –
Altman Z-score 2.37 – –

Shareholder Returns

7 metrics
MetricPFENVSMRK
Dividend yield 5.7% 2.9% 2.3%
Net buyback yield – – –
Shareholder yield 5.7% 2.9% 2.3%
Payout ratio (earnings) 224.5% – –
Payout ratio (FCF) 89.1% – –
Dividend growth (1Y) 1.5% – –
Dividend CAGR (3Y) 2.4% – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusPFENVSMRK
Forward P/E 10.5xFY2026 17.4xFY2026 59.0xFY2026
EPS, next fiscal year $2.85FY2026 $9.26FY2026 $2.48FY2026
EPS growth, next FY -11.5%FY2026 +3.1%FY2026 -72.4%FY2026
EPS growth, the year after -4.6% +1.2% +257.3%
Revenue, next fiscal year $60.59BFY2026 $53.95BFY2026 $69.45BFY2026
Revenue growth, next FY -3.2%FY2026 -1.1%FY2026 +6.8%FY2026
Revenue growth, the year after +3.9% +19.1% -3.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersPFENVSMRK
Held by institutions 66.9% 7.0% 79.9%
Institutions holding 2,837 1,608 3,798
Change in shares held, QoQ +2.0% -5.9% +2.6%
Institutions buying 1,326 662 1,843
Institutions selling 1,204 561 1,465
Buyers to sellers 1.10 1.18 1.26

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

PFENVSMRK
PFE 1.00 0.49 0.45
NVS 0.49 1.00 0.47
MRK 0.45 0.47 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, PFE, NVS and MRK?

Merck (MRK) is the largest by market capitalisation: Pfizer (PFE) $173.68B, Novartis Ag (NVS) $311.97B, Merck (MRK) $370.60B.

Which stock is cheaper, PFE, NVS and MRK?

Novartis Ag (NVS) trades on the lowest price-to-earnings ratio (Pfizer (PFE) 40.1x, Novartis Ag (NVS) 17.9x, Merck (MRK) 151.1x). On next year's consensus earnings, Pfizer (PFE) is cheapest (Pfizer (PFE) 10.5x, Novartis Ag (NVS) 17.4x, Merck (MRK) 59.0x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Merck (MRK) grew revenue fastest over the trailing twelve months: Pfizer (PFE) -0.2%, Merck (MRK) +4.9%.

Which stock has performed better?

Over the past year Merck (MRK) returned the most: Pfizer (PFE) +23.3%, Novartis Ag (NVS) +32.2%, Merck (MRK) +69.0%. Over five years, Novartis Ag (NVS) compounded fastest (Pfizer (PFE) -7.3%/yr, Novartis Ag (NVS) +14.3%/yr, Merck (MRK) +10.7%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Pfizer (PFE) 0.06%, Novartis Ag (NVS) 0.00%, Merck (MRK) 0.00%. Novartis Ag (NVS) and Merck (MRK) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Pfizer (PFE) has been the steadiest (Pfizer (PFE) 21.7%, Novartis Ag (NVS) 27.6%, Merck (MRK) 29.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, PFE, NVS and MRK?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Merck (MRK) leads on 3. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.