NXTS vs PTCT vs ALNY Stock Comparison

Nexentis Technologies, Ptc Therapeutics and Alnylam Pharmaceuticals Prices as of Oct 28, 2026 Peers: Industry group

Head to Head

9 decided of 12

Alnylam Pharmaceuticals leads on 5 of the 12 questions below (Alnylam Pharmaceuticals 5, Ptc Therapeutics 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionNXTSPTCTALNYLeader
Larger companyMarket capitalisation $514.17K $5.25B $31.08B ALNY
Cheaper on earningsLower P/E, profitable companies only 0.0x -136.3x 42.4x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 57.3x 34.4x ALNY
Faster revenue growthRevenue growth, trailing twelve months — -42.8% +90.1% ALNY
More profitableNet margin, trailing twelve months — -3.8% 15.3% ALNY
Better return on capitalReturn on invested capital — 12.5% — –
Less leveragedLower net debt / EBITDA 1.6x -7.3x — PTCT
Higher dividend yieldTrailing dividend yield — — — –
Better 1-year returnPrice return, last 12 months -97.4% -6.6% -51.2% PTCT
Better 5-year returnAnnualised price return, 5 years -85.8%/yr +10.7%/yr +7.8%/yr PTCT
Less volatileAnnualised volatility, 1 year 169.0% 40.8% 51.3% PTCT
Higher overall scoreMean of the five percentile scores vs peers 32/100 64/100 77/100 ALNY

Percentile Scorecard

NXTSPTCTALNY

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisNXTSPTCTALNY
Valuation – 95 #35 of 625 81 #119 of 625
Growth 14 #521 of 602 42 #349 of 602 98 #13 of 602
Profitability 40 #330 of 549 86 #76 of 549 93 #41 of 549
Financial Health 43 #372 of 654 42 #380 of 654 46 #357 of 654
Shareholder Returns – 56 #163 of 367 68 #120 of 367
Overall 32 64 77
  • NXTS ranked among 672 companies in Pharmaceuticals and Biotechnology
  • PTCT ranked among 672 companies in Pharmaceuticals and Biotechnology
  • ALNY ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodNXTSPTCTALNYSPY
1 month -57.1%-4.4%-9.0% +0.9%
3 months -57.4%-15.4%-18.9% +5.9%
6 months -86.6%-2.4%-22.8% +8.5%
Year to date -94.6%-17.0%-41.6% +13.3%
1 year -97.4%-6.6%-51.2% +12.4%
3 years -99.9%+240.5%+53.1% +88.1%
3 years, per year -89.2%+50.5%+15.3% +23.5%
5 years -100.0%+66.1%+45.7% +68.2%
5 years, per year -85.8%+10.7%+7.8% +11.0%
10 years -100.0%+886.2%+539.5% +263.4%
10 years, per year -66.2%+25.7%+20.4% +13.8%

Risk

MeasureNXTSPTCTALNYSPY
Volatility, 1Y 169.0%40.8%51.3% 12.7%
Downside volatility, 1Y 153.5%40.9%62.9% 12.7%
Beta vs S&P 500, 1Y 2.350.720.35 1.00
Return / volatility, 1Y -0.58-0.16-1.00 0.98
Max drawdown, 5Y -100.0%-69.4%-58.2% -25.4%
From 52-week high -97.4%-29.6%-51.7% -0.9%
52-week high $24.15$89.55$481.59 $779.14
52-week low $0.53$59.24$205.48 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleNXTSPTCTALNY
P/E now vs peer median 0.0xmedian 17.4x -136.3xmedian 17.4x 42.4xmedian 17.4x
P/S now vs peer median —median 9.1x 5.2xmedian 9.1x 6.5xmedian 9.1x
EV/EBITDA now vs peer median 1.5xmedian 17.1x 21.6xmedian 17.1x 26.3xmedian 17.1x
P/FCF now vs peer median —median 19.0x -132.0xmedian 19.0x 37.9xmedian 19.0x
P/B now vs peer median 0.3xmedian 2.2x -31.8xmedian 2.2x 23.0xmedian 2.2x
PEG now vs peer median 0.00median 0.34 -2.16median 0.34 1.12median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsNXTSPTCTALNY
Revenue – $1.01B $4.80B
Gross profit – $938.07M $3.83B
Operating income -$5.28M $125.60M $999.78M
Net income -$14.06M -$38.38M $733.11M
Free cash flow – -$39.78M $819.87M
R&D $532.00K $433.31M $1.51B
EPS (diluted) $-17.10 $-0.42 $5.30
Cash & equivalents $7.62M $1.05B $1.71B
Total debt $3.22M $905.19M –
Shares (diluted) 816.14K 92.02M 138.28M
Enterprise value -$22.25M -$2.50B $19.13B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricNXTSPTCTALNY
P/E 0.0x -136.3x 42.4x
P/FCF – -132.0x 37.9x
P/Operating cash flow – -172.2x 34.1x
P/S – 5.2x 6.5x
P/B 0.3x -31.8x 23.0x
P/Tangible book -0.2x -9.2x 23.0x
EV/EBITDA 1.5x 21.6x 26.3x
EV/EBIT 1.5x 31.3x 27.8x
EV/Revenue – 3.9x 5.8x
EV/FCF – -98.7x 33.9x
EV/Operating cash flow – -128.8x 30.5x
PEG (3Y EPS CAGR) 0.00 -2.16 1.12

Growth

14 metrics
MetricNXTSPTCTALNY
Revenue growth (1Y) – -42.8% 90.1%
Revenue CAGR (3Y) – 7.2% 57.2%
Gross profit growth (1Y) – -45.3% 79.7%
Gross profit CAGR (3Y) – 6.9% 54.6%
Operating income growth (1Y) -7.7% -82.5% 654.9%
Operating income CAGR (3Y) 3.0% 30.3% 47.5%
Net income growth (1Y) -48.2% -106.1% 356.5%
Net income CAGR (3Y) -35.8% 60.4% 39.1%
EPS growth (1Y) -567.8% -105.2% 342.3%
EPS CAGR (3Y) -45.2% 63.1% 37.9%
Operating cash flow growth (1Y) – -104.3% 2,299%
Operating cash flow CAGR (3Y) – 50.2% 57.8%
Free cash flow growth (1Y) – -105.7% 1,151%
Free cash flow CAGR (3Y) – 47.7% 52.1%

Profitability

14 metrics
MetricNXTSPTCTALNY
Gross margin – 93.0% 79.8%
EBITDA margin – 18.1% 22.0%
Operating margin – 12.5% 20.8%
Pretax margin – -6.6% 16.0%
Net margin – -3.8% 15.3%
FCF margin – -3.9% 17.1%
Operating cash flow margin – -3.0% 19.0%
Return on equity -157.0% – 63.8%
Return on assets -71.9% -1.3% 14.5%
Return on invested capital – 12.5% –
Return on capital employed -31.5% 5.5% 26.1%
Asset turnover – 0.3x 0.9x
Cash conversion (OCF / net income) – 0.8x 1.2x
Stock comp / revenue – 8.4% 7.0%

Financial Health

11 metrics
MetricNXTSPTCTALNY
Debt / assets 2.3% 27.8% –
Debt / equity 0.2x -5.5x –
Net debt / EBITDA 1.6x -7.3x –
Debt / FCF – -22.8x –
Liabilities / assets 89.8% 105.1% 75.6%
Equity / assets 10.2% -5.1% 24.4%
Interest coverage – – 3.8x
Current ratio 3.7x 3.4x 3.1x
Quick ratio 3.2x 3.2x 2.8x
Cash ratio 3.2x 2.9x 2.2x
Altman Z-score – 0.80 4.97

Shareholder Returns

7 metrics
MetricNXTSPTCTALNY
Dividend yield – – –
Net buyback yield – -1.9% -0.5%
Shareholder yield – -1.9% -0.5%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusNXTSPTCTALNY
Forward P/E – 57.3xFY2026 34.4xFY2026
EPS, next fiscal year – $1.10FY2026 $6.76FY2026
EPS growth, next FY – -85.9%FY2026 +190.1%FY2026
EPS growth, the year after – +125.5% +34.3%
Revenue, next fiscal year – $1.33BFY2026 $5.68BFY2026
Revenue growth, next FY – -23.2%FY2026 +53.1%FY2026
Revenue growth, the year after – -1.0% +27.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersNXTSPTCTALNY
Held by institutions – 100.0% 99.7%
Institutions holding – 381 786
Change in shares held, QoQ – +5.0% +3.8%
Institutions buying – 218 412
Institutions selling – 111 277
Buyers to sellers – 1.96 1.49

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

NXTSPTCTALNY
NXTS 1.00 0.02 0.03
PTCT 0.02 1.00 0.17
ALNY 0.03 0.17 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, NXTS, PTCT and ALNY?

Alnylam Pharmaceuticals (ALNY) is the largest by market capitalisation: Nexentis Technologies (NXTS) $514.17K, Ptc Therapeutics (PTCT) $5.25B, Alnylam Pharmaceuticals (ALNY) $31.08B.

Which company is growing faster?

Alnylam Pharmaceuticals (ALNY) grew revenue fastest over the trailing twelve months: Ptc Therapeutics (PTCT) -42.8%, Alnylam Pharmaceuticals (ALNY) +90.1%.

Which company is more profitable?

Alnylam Pharmaceuticals (ALNY) has the highest net margin (Ptc Therapeutics (PTCT) -3.8%, Alnylam Pharmaceuticals (ALNY) 15.3%).

Which stock has performed better?

Over the past year Ptc Therapeutics (PTCT) returned the most: Nexentis Technologies (NXTS) -97.4%, Ptc Therapeutics (PTCT) -6.6%, Alnylam Pharmaceuticals (ALNY) -51.2%. Over five years, Ptc Therapeutics (PTCT) compounded fastest (Nexentis Technologies (NXTS) -85.8%/yr, Ptc Therapeutics (PTCT) +10.7%/yr, Alnylam Pharmaceuticals (ALNY) +7.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Ptc Therapeutics (PTCT) has been the steadiest (Nexentis Technologies (NXTS) 169.0%, Ptc Therapeutics (PTCT) 40.8%, Alnylam Pharmaceuticals (ALNY) 51.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, NXTS, PTCT and ALNY?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Alnylam Pharmaceuticals (ALNY) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.