NXTS vs PTCT vs ALNY Stock Comparison

Nexentis Technologies, Ptc Therapeutics and Alnylam Pharmaceuticals Prices as of Nov 3, 2026 Peers: Industry group
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Head to Head

9 decided of 12

Alnylam Pharmaceuticals leads on 5 of the 12 questions below (Alnylam Pharmaceuticals 5, Ptc Therapeutics 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionNXTSPTCTALNYLeader
Larger companyMarket capitalisation $441.45K $5.73B $21.63B ALNY
Cheaper on earningsLower P/E, profitable companies only 0.0x -54.0x 8.2x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 61.9x 23.7x ALNY
Faster revenue growthRevenue growth, trailing twelve months — -35.1% +60.8% ALNY
More profitableNet margin, trailing twelve months — -9.2% 52.8% ALNY
Better return on capitalReturn on invested capital — 21.0% — –
Less leveragedLower net debt / EBITDA 0.8x -6.0x -3.1x PTCT
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -97.6% +0.3% -63.2% PTCT
Better 5-year returnAnnualised price return, 5 years -86.4%/yr +10.4%/yr -2.9%/yr PTCT
Less volatileAnnualised volatility, 1 year 169.6% 43.0% 58.6% PTCT
Higher overall scoreMean of the five percentile scores vs peers 20/100 63/100 82/100 ALNY

Percentile Scorecard

NXTSPTCTALNY

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisNXTSPTCTALNY
Valuation 9 #579 of 634 95 #36 of 634 92 #55 of 634
Growth 9 #551 of 607 40 #363 of 607 99 #8 of 607
Profitability 21 #440 of 557 87 #74 of 557 90 #56 of 557
Financial Health 43 #373 of 654 35 #423 of 654 63 #244 of 654
Shareholder Returns – 58 #170 of 401 68 #131 of 401
Overall 20 63 82
  • NXTS ranked among 671 companies in Pharmaceuticals and Biotechnology
  • PTCT ranked among 671 companies in Pharmaceuticals and Biotechnology
  • ALNY ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodNXTSPTCTALNYSPY
1 month -60.4%+7.3%-27.2% -2.0%
3 months -71.8%-1.4%-27.0% -2.2%
6 months -87.7%+4.7%-46.9% +4.2%
Year to date -95.2%-10.3%-59.8% +10.6%
1 year -97.6%+0.3%-63.2% +10.4%
3 years -99.9%+248.8%-4.5% +73.6%
3 years, per year -90.3%+51.7%-1.5% +20.2%
5 years -100.0%+63.8%-13.8% +61.6%
5 years, per year -86.4%+10.4%-2.9% +10.1%
10 years -100.0%+1,525.8%+409.0% +261.3%
10 years, per year -66.5%+32.2%+17.7% +13.7%

Risk

MeasureNXTSPTCTALNYSPY
Volatility, 1Y 169.6%43.0%58.6% 12.8%
Downside volatility, 1Y 154.9%42.4%74.5% 12.8%
Beta vs S&P 500, 1Y 2.420.810.44 1.00
Return / volatility, 1Y -0.580.01-1.08 0.81
Max drawdown, 5Y -100.0%-69.4%-67.8% -25.4%
From 52-week high -97.6%-23.9%-66.2% -3.2%
52-week high $23.38$89.55$473.29 $779.14
52-week low $0.53$59.24$158.00 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleNXTSPTCTALNY
P/E now vs peer median 0.0xmedian 18.4x -53.7xmedian 18.4x 8.1xmedian 18.4x
P/S now vs peer median —median 9.0x 4.9xmedian 9.0x 4.3xmedian 9.0x
EV/EBITDA now vs peer median 0.8xmedian 16.0x 21.0xmedian 16.0x 17.6xmedian 16.0x
P/FCF now vs peer median -0.1xmedian 21.8x 2,753xmedian 21.8x 26.5xmedian 21.8x
P/B now vs peer median 0.2xmedian 2.1x -29.8xmedian 2.1x 5.9xmedian 2.1x
PEG now vs peer median 0.00median 0.37 -1.14median 0.37 0.09median 0.37

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsNXTSPTCTALNY
Revenue – $1.16B $5.01B
Gross profit – $1.08B $3.88B
Operating income -$10.88M $147.70M $977.59M
Net income -$16.14M -$105.97M $2.65B
Free cash flow -$4.50M $2.07M $806.31M
R&D $798.00K $438.50M $1.56B
EPS (diluted) $-19.64 $-1.27 $19.16
Cash & equivalents $7.62M $508.89M $1.75B
Total debt $422.00K $855.35M $361.53M
Shares (diluted) 816.14K 83.48M 138.28M
Enterprise value -$24.99M -$2.47B $8.82B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricNXTSPTCTALNY
P/E 0.0x -53.7x 8.1x
P/FCF -0.1x 2,753x 26.5x
P/Operating cash flow -0.1x 542.6x 22.4x
P/S – 4.9x 4.3x
P/B 0.2x -29.8x 5.9x
P/Tangible book -0.2x -9.0x 5.9x
EV/EBITDA 0.8x 21.0x 17.6x
EV/EBIT 0.7x 29.9x 18.6x
EV/Revenue – 3.8x 3.6x
EV/FCF 1.8x 2,137x 22.5x
EV/Operating cash flow 1.8x 421.3x 19.0x
PEG (3Y EPS CAGR) 0.00 -1.14 0.09

Growth

14 metrics
MetricNXTSPTCTALNY
Revenue growth (1Y) – -35.1% 60.8%
Revenue CAGR (3Y) – 13.1% 42.7%
Gross profit growth (1Y) – -37.5% 49.6%
Gross profit CAGR (3Y) – 12.8% 37.8%
Operating income growth (1Y) -127.3% -81.0% 269.3%
Operating income CAGR (3Y) -23.5% 30.6% 68.2%
Net income growth (1Y) -70.1% -114.1% 2,137%
Net income CAGR (3Y) -42.2% 45.1% 93.1%
EPS growth (1Y) -666.9% -114.7% 2,122%
EPS CAGR (3Y) -52.0% 47.0% 90.7%
Operating cash flow growth (1Y) -62.8% -98.5% 351.6%
Operating cash flow CAGR (3Y) -0.4% 27.0% 685.4%
Free cash flow growth (1Y) -65.5% -99.7% 382.3%
Free cash flow CAGR (3Y) -0.7% 26.2% 141.7%

Profitability

14 metrics
MetricNXTSPTCTALNY
Gross margin – 93.2% 77.4%
EBITDA margin – 18.2% 20.6%
Operating margin – 12.8% 19.5%
Pretax margin – -7.4% 15.6%
Net margin – -9.2% 52.8%
FCF margin – 0.2% 16.1%
Operating cash flow margin – 0.9% 19.1%
Return on equity -218.6% – 106.9%
Return on assets -92.0% -3.3% 39.1%
Return on invested capital – 21.0% –
Return on capital employed -73.7% 6.0% 20.7%
Asset turnover – 0.4x 0.7x
Cash conversion (OCF / net income) 0.3x -0.1x 0.4x
Stock comp / revenue – 7.7% 6.1%

Financial Health

11 metrics
MetricNXTSPTCTALNY
Debt / assets 2.3% 26.7% 4.5%
Debt / equity 0.2x -4.5x 0.1x
Net debt / EBITDA 0.8x -6.0x -3.1x
Debt / FCF -0.1x 413.8x 0.4x
Liabilities / assets 89.8% 106.0% 54.9%
Equity / assets 10.2% -6.0% 45.1%
Interest coverage – – 3.2x
Current ratio 3.7x 3.3x 2.5x
Quick ratio 3.2x 3.0x 2.3x
Cash ratio 3.2x 2.7x 1.7x
Altman Z-score – 0.89 3.68

Shareholder Returns

7 metrics
MetricNXTSPTCTALNY
Dividend yield – – –
Net buyback yield -2,098% -1.6% -0.5%
Shareholder yield -2,098% -1.6% -0.5%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusNXTSPTCTALNY
Forward P/E – 61.9xFY2026 23.7xFY2026
EPS, next fiscal year – $1.10FY2026 $6.76FY2026
EPS growth, next FY – -85.9%FY2026 +190.1%FY2026
EPS growth, the year after – +125.5% +34.3%
Revenue, next fiscal year – $1.33BFY2026 $5.68BFY2026
Revenue growth, next FY – -23.2%FY2026 +53.1%FY2026
Revenue growth, the year after – -1.0% +27.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersNXTSPTCTALNY
Held by institutions – 100.0% 99.7%
Institutions holding – 383 788
Change in shares held, QoQ – +5.0% +3.8%
Institutions buying – 218 412
Institutions selling – 111 279
Buyers to sellers – 1.96 1.48

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

NXTSPTCTALNY
NXTS 1.00 0.04 0.03
PTCT 0.04 1.00 0.13
ALNY 0.03 0.13 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, NXTS, PTCT and ALNY?

Alnylam Pharmaceuticals (ALNY) is the largest by market capitalisation: Nexentis Technologies (NXTS) $441.45K, Ptc Therapeutics (PTCT) $5.73B, Alnylam Pharmaceuticals (ALNY) $21.63B.

Which company is growing faster?

Alnylam Pharmaceuticals (ALNY) grew revenue fastest over the trailing twelve months: Ptc Therapeutics (PTCT) -35.1%, Alnylam Pharmaceuticals (ALNY) +60.8%.

Which company is more profitable?

Alnylam Pharmaceuticals (ALNY) has the highest net margin (Ptc Therapeutics (PTCT) -9.2%, Alnylam Pharmaceuticals (ALNY) 52.8%).

Which stock has performed better?

Over the past year Ptc Therapeutics (PTCT) returned the most: Nexentis Technologies (NXTS) -97.6%, Ptc Therapeutics (PTCT) +0.3%, Alnylam Pharmaceuticals (ALNY) -63.2%. Over five years, Ptc Therapeutics (PTCT) compounded fastest (Nexentis Technologies (NXTS) -86.4%/yr, Ptc Therapeutics (PTCT) +10.4%/yr, Alnylam Pharmaceuticals (ALNY) -2.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Ptc Therapeutics (PTCT) has been the steadiest (Nexentis Technologies (NXTS) 169.6%, Ptc Therapeutics (PTCT) 43.0%, Alnylam Pharmaceuticals (ALNY) 58.6%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, NXTS, PTCT and ALNY?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Alnylam Pharmaceuticals (ALNY) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.