NTRA vs GH vs ADPT Stock Comparison

Natera, Guardant Health and Adaptive Biotechnologies Prices as of Oct 29, 2026 Peers: Industry group
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NTRA Natera, Inc.
$436.00 +5.2% 1M +126.1% 1Y
Market cap
$55.91B
P/E
–
Revenue (TTM)
$2.71B
Div. yield
–
Diagnostic Labs Healthcare
5 wins
GH Guardant Health, Inc.
$185.31 +4.3% 1M +156.4% 1Y
Market cap
$23.24B
P/E
–
Revenue (TTM)
$1.18B
Div. yield
–
Diagnostic Labs Healthcare
1 win

Head to Head

7 decided of 12

Natera leads on 5 of the 12 questions below (Natera 5, Adaptive Biotechnologies 1, Guardant Health 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionNTRAGHADPTLeader
Larger companyMarket capitalisation $55.91B $23.24B $4.15B NTRA
Cheaper on earningsLower P/E, profitable companies only -290.6x -51.3x -65.0x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months +37.8% +42.7% +50.1% ADPT
More profitableNet margin, trailing twelve months -7.1% -38.3% -20.7% NTRA
Better return on capitalReturn on invested capital -11.7% — — –
Less leveragedLower net debt / EBITDA 4.5x — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +126.1% +156.4% +67.7% GH
Better 5-year returnAnnualised price return, 5 years +30.7%/yr +9.7%/yr -3.4%/yr NTRA
Less volatileAnnualised volatility, 1 year 47.9% 57.3% 67.8% NTRA
Higher overall scoreMean of the five percentile scores vs peers 51/100 28/100 43/100 NTRA

Percentile Scorecard

NTRAGHADPT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisNTRAGHADPT
Valuation 17 #77 of 92 18 #76 of 92 15 #78 of 92
Growth 71 #26 of 87 48 #46 of 87 85 #14 of 87
Profitability 32 #59 of 86 7 #80 of 86 25 #65 of 86
Financial Health 85 #15 of 97 55 #44 of 97 66 #34 of 97
Shareholder Returns 52 #27 of 55 15 #47 of 55 26 #41 of 55
Overall 51 28 43
  • NTRA ranked among 102 companies in Healthcare Providers
  • GH ranked among 102 companies in Healthcare Providers
  • ADPT ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodNTRAGHADPTSPY
1 month +5.2%+4.3%-2.1% +0.7%
3 months +61.7%+21.6%+16.5% +3.7%
6 months +111.5%+112.8%+99.8% +7.1%
Year to date +90.3%+81.4%+73.5% +12.8%
1 year +126.1%+156.4%+67.7% +11.9%
3 years +1,061.1%+631.6%+550.6% +85.2%
3 years, per year +126.6%+94.2%+86.8% +22.8%
5 years +280.6%+58.7%-15.7% +67.6%
5 years, per year +30.7%+9.7%-3.4% +10.9%
10 years +5,023.4%—— +262.0%
10 years, per year +48.2%—— +13.7%

Risk

MeasureNTRAGHADPTSPY
Volatility, 1Y 47.9%57.3%67.8% 12.7%
Downside volatility, 1Y 44.6%48.9%63.9% 12.6%
Beta vs S&P 500, 1Y 1.231.031.68 1.00
Return / volatility, 1Y 2.632.731.00 0.94
Max drawdown, 5Y -76.4%-86.7%-93.6% -25.4%
From 52-week high 0.0%-1.0%-5.6% -1.2%
52-week high $436.00$187.22$29.84 $779.14
52-week low $182.65$72.27$12.41 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleNTRAGHADPT
P/E now vs peer median -324.7xmedian 26.0x -54.3xmedian 26.0x -70.5xmedian 26.0x
P/S now vs peer median 23.1xmedian 1.6x 20.9xmedian 1.6x 14.5xmedian 1.6x
EV/EBITDA now vs peer median -274.7xmedian 15.4x -54.9xmedian 15.4x -192.3xmedian 15.4x
P/FCF now vs peer median 743.7xmedian 21.5x -102.9xmedian 21.5x -186.4xmedian 21.5x
P/B now vs peer median 34.4xmedian 3.2x -111.1xmedian 3.2x 29.7xmedian 3.2x
PEG now vs peer median -9.78median 0.87 -5.47median 0.87 -2.14median 0.87

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsNTRAGHADPT
Revenue $2.71B $1.18B $308.08M
Gross profit $1.71B $769.16M $232.83M
Operating income -$289.67M -$470.26M -$37.46M
Net income -$192.36M -$453.44M -$63.99M
Free cash flow $84.20M -$240.72M -$24.03M
R&D $787.38M $375.79M $88.21M
EPS (diluted) $-1.34 $-3.41 $-0.40
Cash & equivalents $1.10B $1.05B $169.87M
Total debt $80.29M – –
Shares (diluted) 143.28M 132.87M 159.86M
Enterprise value $51.59B $19.31B $3.15B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricNTRAGHADPT
P/E -324.7x -54.3x -70.5x
P/FCF 743.7x -102.9x -186.4x
P/Operating cash flow 274.3x -133.7x -213.3x
P/S 23.1x 20.9x 14.5x
P/B 34.4x -111.1x 29.7x
P/Tangible book 42.8x -99.8x 29.9x
EV/EBITDA -274.7x -54.9x -192.3x
EV/EBIT -212.6x -50.4x -110.4x
EV/Revenue 22.8x 20.0x 13.4x
EV/FCF 731.6x -98.5x -172.1x
EV/Operating cash flow 269.9x -128.0x -196.9x
PEG (3Y EPS CAGR) -9.78 -5.47 -2.14

Growth

14 metrics
MetricNTRAGHADPT
Revenue growth (1Y) 37.8% 42.7% 50.1%
Revenue CAGR (3Y) 42.7% 32.4% 17.6%
Gross profit growth (1Y) 43.6% 47.7% 71.8%
Gross profit CAGR (3Y) 68.1% – 24.2%
Operating income growth (1Y) 1.3% -2.1% 69.1%
Operating income CAGR (3Y) 17.3% 4.8% 41.8%
Net income growth (1Y) 24.0% -9.6% 47.2%
Net income CAGR (3Y) 27.8% 3.7% 30.5%
EPS growth (1Y) 27.7% -2.4% 49.9%
EPS CAGR (3Y) 33.2% 9.9% 32.9%
Operating cash flow growth (1Y) 22.2% 22.4% 73.9%
Operating cash flow CAGR (3Y) 38.6% 18.1% 48.6%
Free cash flow growth (1Y) -26.8% 11.4% 71.0%
Free cash flow CAGR (3Y) 30.4% 14.4% 47.9%

Profitability

14 metrics
MetricNTRAGHADPT
Gross margin 63.2% 65.0% 75.6%
EBITDA margin -8.3% -36.5% -7.0%
Operating margin -10.7% -39.7% -12.2%
Pretax margin -9.3% -38.4% -13.1%
Net margin -7.1% -38.3% -20.7%
FCF margin 3.1% -20.3% -7.8%
Operating cash flow margin 8.4% -15.7% -6.8%
Return on equity -10.7% – -34.1%
Return on assets -7.3% -23.7% -11.2%
Return on invested capital -11.7% – –
Return on capital employed -13.9% -29.9% -7.7%
Asset turnover 1.0x 0.6x 0.5x
Cash conversion (OCF / net income) -1.2x 0.4x 0.3x
Stock comp / revenue 14.1% 16.2% 15.9%

Financial Health

11 metrics
MetricNTRAGHADPT
Debt / assets 3.0% – –
Debt / equity 0.0x – –
Net debt / EBITDA 4.5x – –
Debt / FCF 1.0x – –
Liabilities / assets 31.5% 111.7% 76.5%
Equity / assets 68.5% -11.7% 23.5%
Interest coverage -75.9x -97.6x -3.3x
Current ratio 3.0x 4.0x 4.8x
Quick ratio 2.8x 3.5x 4.5x
Cash ratio 2.0x 3.1x 3.9x
Altman Z-score 44.55 5.05 3.29

Shareholder Returns

7 metrics
MetricNTRAGHADPT
Dividend yield – – –
Net buyback yield -0.1% -1.6% -0.5%
Shareholder yield -0.1% -1.6% -0.5%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusNTRAGHADPT
EPS, next fiscal year $-1.48FY2026 $-3.33FY2026 $-0.57FY2026
Revenue, next fiscal year $3.07BFY2026 $1.42BFY2026 $284.03MFY2026
Revenue growth, next FY +32.8%FY2026 +44.5%FY2026 +2.5%FY2026
Revenue growth, the year after +7.2% +27.0% +33.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersNTRAGHADPT
Held by institutions 95.5% 100.0% 97.2%
Institutions holding 848 595 300
Change in shares held, QoQ +2.7% -2.6% +2.5%
Institutions buying 514 354 160
Institutions selling 240 180 87
Buyers to sellers 2.14 1.97 1.84

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

NTRAGHADPT
NTRA 1.00 0.60 0.56
GH 0.60 1.00 0.53
ADPT 0.56 0.53 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, NTRA, GH and ADPT?

Natera (NTRA) is the largest by market capitalisation: Natera (NTRA) $55.91B, Guardant Health (GH) $23.24B, Adaptive Biotechnologies (ADPT) $4.15B.

Which company is growing faster?

Adaptive Biotechnologies (ADPT) grew revenue fastest over the trailing twelve months: Natera (NTRA) +37.8%, Guardant Health (GH) +42.7%, Adaptive Biotechnologies (ADPT) +50.1%.

Which company is more profitable?

Natera (NTRA) has the highest net margin (Natera (NTRA) -7.1%, Guardant Health (GH) -38.3%, Adaptive Biotechnologies (ADPT) -20.7%).

Which stock has performed better?

Over the past year Guardant Health (GH) returned the most: Natera (NTRA) +126.1%, Guardant Health (GH) +156.4%, Adaptive Biotechnologies (ADPT) +67.7%. Over five years, Natera (NTRA) compounded fastest (Natera (NTRA) +30.7%/yr, Guardant Health (GH) +9.7%/yr, Adaptive Biotechnologies (ADPT) -3.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Natera (NTRA) has been the steadiest (Natera (NTRA) 47.9%, Guardant Health (GH) 57.3%, Adaptive Biotechnologies (ADPT) 67.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, NTRA, GH and ADPT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Natera (NTRA) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.