NTLA vs SLBT vs SRPT Stock Comparison

Intellia Therapeutics, SL Science Holding and Sarepta Therapeutics Prices as of Oct 27, 2026 Peers: Industry group
SLBT SL Science Holding Ltd
$1.19 -24.2% 1M -88.5% 1Y
Market cap
$2.69B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
1 win

Head to Head

7 decided of 12

Intellia Therapeutics leads on 3 of the 12 questions below (Intellia Therapeutics 3, Sarepta Therapeutics 3, SL Science Holding 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionNTLASLBTSRPTLeader
Larger companyMarket capitalisation $1.75B $2.69B $2.02B SLBT
Cheaper on earningsLower P/E, profitable companies only -4.4x — -17.3x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 6.6x –
Faster revenue growthRevenue growth, trailing twelve months +12.6% — -20.4% NTLA
More profitableNet margin, trailing twelve months -672.2% — -5.9% SRPT
Better return on capitalReturn on invested capital — — -6.1% –
Less leveragedLower net debt / EBITDA — — -0.6x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -17.0% -88.5% -19.6% NTLA
Better 5-year returnAnnualised price return, 5 years -38.2%/yr — -24.9%/yr SRPT
Less volatileAnnualised volatility, 1 year 79.8% 175.4% 81.2% NTLA
Higher overall scoreMean of the five percentile scores vs peers 49/100 — 67/100 SRPT

Percentile Scorecard

NTLASLBTSRPT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisNTLASLBTSRPT
Valuation 34 #415 of 625 11 #555 of 625 96 #25 of 625
Growth 63 #221 of 602 – 64 #218 of 602
Profitability 39 #338 of 551 – 80 #114 of 551
Financial Health 72 #186 of 656 58 #279 of 656 34 #435 of 656
Shareholder Returns 39 #223 of 365 – 60 #145 of 365
Overall 49 – 67
  • NTLA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • SLBT ranked among 672 companies in Pharmaceuticals and Biotechnology
  • SRPT ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodNTLASLBTSRPTSPY
1 month +4.5%-24.2%+1.2% -0.2%
3 months +12.8%-56.7%+22.4% +3.9%
6 months -7.0%-84.9%-10.3% +8.2%
Year to date +36.6%-88.7%-12.2% +12.9%
1 year -17.0%-88.5%-19.6% +12.3%
3 years -47.0%—-82.3% +87.4%
3 years, per year -19.1%—-43.9% +23.3%
5 years -91.0%—-76.2% +67.9%
5 years, per year -38.2%—-24.9% +10.9%
10 years -4.8%—-53.7% +261.1%
10 years, per year -0.5%—-7.4% +13.7%

Risk

MeasureNTLASLBTSRPTSPY
Volatility, 1Y 79.8%175.4%81.2% 12.7%
Downside volatility, 1Y 82.3%170.6%85.9% 12.7%
Beta vs S&P 500, 1Y 2.440.232.08 1.00
Return / volatility, 1Y -0.21-0.50-0.24 0.97
Max drawdown, 5Y -95.5%-91.0%-92.7% -25.4%
From 52-week high -31.2%-90.7%-22.7% -1.2%
52-week high $17.84$12.81$24.45 $779.14
52-week low $8.04$1.15$14.86 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleNTLASLBTSRPT
P/E now vs peer median -4.1xmedian 17.2x —median 17.2x -17.0xmedian 17.2x
P/S now vs peer median 28.9xmedian 9.0x —median 9.0x 1.0xmedian 9.0x
EV/EBITDA now vs peer median -3.1xmedian 16.3x —median 16.3x -20.8xmedian 16.3x
P/FCF now vs peer median -4.9xmedian 18.7x -1,382xmedian 18.7x 24.4xmedian 18.7x
P/B now vs peer median 2.4xmedian 2.2x 372.2xmedian 2.2x 1.3xmedian 2.2x
PEG now vs peer median -0.25median 0.33 —median 0.33 -0.33median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsNTLASLBTSRPT
Revenue $59.51M – $1.97B
Gross profit – – $1.17B
Operating income -$423.48M – -$143.25M
Net income -$399.98M – -$136.73M
Free cash flow -$348.69M – $81.85M
R&D $346.73M – $789.44M
EPS (diluted) $-3.00 – $-1.11
Cash & equivalents $106.13M $8.31M $571.15M
Total debt – – $847.62M
Shares (diluted) 133.48M – 105.43M
Enterprise value -$26.08M $2.68B -$1.21B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricNTLASLBTSRPT
P/E -4.1x – -17.0x
P/FCF -4.9x -1,382x 24.4x
P/Operating cash flow -5.0x – 18.0x
P/S 28.9x – 1.0x
P/B 2.4x 372.2x 1.3x
P/Tangible book 2.4x 372.2x 1.3x
EV/EBITDA -3.1x – -20.8x
EV/EBIT -3.0x – -14.3x
EV/Revenue 21.5x – 1.0x
EV/FCF -3.7x – 25.1x
EV/Operating cash flow -3.7x – 18.5x
PEG (3Y EPS CAGR) -0.25 – -0.33

Growth

14 metrics
MetricNTLASLBTSRPT
Revenue growth (1Y) 12.6% – -20.4%
Revenue CAGR (3Y) 3.9% – 25.3%
Gross profit growth (1Y) – – -40.7%
Gross profit CAGR (3Y) – – 10.6%
Operating income growth (1Y) 17.3% – -15,270%
Operating income CAGR (3Y) 2.7% – 34.5%
Net income growth (1Y) 16.7% – -135.9%
Net income CAGR (3Y) 4.1% – 46.8%
EPS growth (1Y) 35.3% – -215.7%
EPS CAGR (3Y) 16.5% – 52.3%
Operating cash flow growth (1Y) 17.2% – 136.9%
Operating cash flow CAGR (3Y) 2.0% – 30.6%
Free cash flow growth (1Y) 17.3% – 118.1%
Free cash flow CAGR (3Y) 3.2% – 29.1%

Profitability

14 metrics
MetricNTLASLBTSRPT
Gross margin – – 59.1%
EBITDA margin -696.4% – -5.0%
Operating margin -711.7% – -7.3%
Pretax margin -671.0% – -6.6%
Net margin -672.2% – -5.9%
FCF margin -586.0% – 4.1%
Operating cash flow margin -582.5% – 5.6%
Return on equity -59.2% – -9.0%
Return on assets -49.4% – -4.3%
Return on invested capital – – -6.1%
Return on capital employed -58.1% – -5.3%
Asset turnover 0.1x – 0.6x
Cash conversion (OCF / net income) 0.9x – -0.8x
Stock comp / revenue 114.1% – 6.3%

Financial Health

11 metrics
MetricNTLASLBTSRPT
Debt / assets – – 26.6%
Debt / equity – – 0.6x
Net debt / EBITDA – – -0.6x
Debt / FCF – – 10.4x
Liabilities / assets 15.1% 21.8% 52.1%
Equity / assets 84.9% 78.2% 47.9%
Interest coverage – – –
Current ratio 6.6x 4.4x 4.4x
Quick ratio 5.6x 4.3x 2.4x
Cash ratio 5.5x 4.3x 1.6x
Altman Z-score 2.47 – -0.16

Shareholder Returns

7 metrics
MetricNTLASLBTSRPT
Dividend yield – – –
Net buyback yield -7.7% – -1.1%
Shareholder yield -7.7% 0.0% -1.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusNTLASLBTSRPT
Forward P/E – – 6.6xFY2026
EPS, next fiscal year $-3.38FY2026 – $2.88FY2026
EPS growth, the year after – – -88.5%
Revenue, next fiscal year $48.94MFY2026 – $1.76BFY2026
Revenue growth, next FY -27.7%FY2026 – -20.1%FY2026
Revenue growth, the year after +158.6% – -21.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersNTLASLBTSRPT
Held by institutions 100.0% – 100.0%
Institutions holding 329 – 324
Change in shares held, QoQ +30.5% – +4.5%
Institutions buying 195 – 148
Institutions selling 78 – 115
Buyers to sellers 2.50 – 1.29

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

NTLASLBTSRPT
NTLA 1.00 -0.09 0.33
SLBT -0.09 1.00 0.00
SRPT 0.33 0.00 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, NTLA, SLBT and SRPT?

SL Science Holding (SLBT) is the largest by market capitalisation: Intellia Therapeutics (NTLA) $1.75B, SL Science Holding (SLBT) $2.69B, Sarepta Therapeutics (SRPT) $2.02B.

Which company is growing faster?

Intellia Therapeutics (NTLA) grew revenue fastest over the trailing twelve months: Intellia Therapeutics (NTLA) +12.6%, Sarepta Therapeutics (SRPT) -20.4%.

Which company is more profitable?

Sarepta Therapeutics (SRPT) has the highest net margin (Intellia Therapeutics (NTLA) -672.2%, Sarepta Therapeutics (SRPT) -5.9%).

Which stock has performed better?

Over the past year Intellia Therapeutics (NTLA) returned the most: Intellia Therapeutics (NTLA) -17.0%, SL Science Holding (SLBT) -88.5%, Sarepta Therapeutics (SRPT) -19.6%. Over five years, Sarepta Therapeutics (SRPT) compounded fastest (Intellia Therapeutics (NTLA) -38.2%/yr, Sarepta Therapeutics (SRPT) -24.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Intellia Therapeutics (NTLA) has been the steadiest (Intellia Therapeutics (NTLA) 79.8%, SL Science Holding (SLBT) 175.4%, Sarepta Therapeutics (SRPT) 81.2%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, NTLA, SLBT and SRPT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Intellia Therapeutics (NTLA) leads on 3. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.