NTLA vs LEGN Stock Comparison

Intellia Therapeutics and Legend Biotech Prices as of Oct 27, 2026 Peers: Industry group
LEGN Legend Biotech Corp
$21.56 +12.8% 1M -32.9% 1Y
Market cap
$4.22B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
6 wins

Head to Head

7 decided of 12

Legend Biotech leads on 6 of the 12 questions below (Legend Biotech 6, Intellia Therapeutics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionNTLALEGNLeader
Larger companyMarket capitalisation $1.74B $4.22B LEGN
Cheaper on earningsLower P/E, profitable companies only -4.3x -46.0x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — –
Faster revenue growthRevenue growth, trailing twelve months +12.6% +59.5% LEGN
More profitableNet margin, trailing twelve months -672.2% -7.2% LEGN
Better return on capitalReturn on invested capital — -4.2% –
Less leveragedLower net debt / EBITDA — 28.0x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -17.0% -32.9% NTLA
Better 5-year returnAnnualised price return, 5 years -38.2%/yr -15.9%/yr LEGN
Less volatileAnnualised volatility, 1 year 79.8% 72.2% LEGN
Higher overall scoreMean of the five percentile scores vs peers 49/100 72/100 LEGN

Percentile Scorecard

NTLALEGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisNTLALEGN
Valuation 34 #415 of 625 89 #70 of 625
Growth 63 #221 of 602 96 #23 of 602
Profitability 39 #338 of 551 80 #112 of 551
Financial Health 72 #186 of 656 54 #305 of 656
Shareholder Returns 39 #223 of 365 43 #209 of 365
Overall 49 72
  • NTLA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • LEGN ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodNTLALEGNSPY
1 month +4.5%+12.8% -0.2%
3 months +12.8%+13.2% +3.9%
6 months -7.0%-8.5% +8.2%
Year to date +36.6%-0.8% +12.9%
1 year -17.0%-32.9% +12.3%
3 years -47.0%-66.1% +87.4%
3 years, per year -19.1%-30.3% +23.3%
5 years -91.0%-57.9% +67.9%
5 years, per year -38.2%-15.9% +10.9%
10 years -4.8%— +261.1%
10 years, per year -0.5%— +13.7%

Risk

MeasureNTLALEGNSPY
Volatility, 1Y 79.8%72.2% 12.7%
Downside volatility, 1Y 82.3%62.7% 12.7%
Beta vs S&P 500, 1Y 2.440.43 1.00
Return / volatility, 1Y -0.21-0.46 0.97
Max drawdown, 5Y -95.5%-78.2% -25.4%
From 52-week high -31.2%-40.6% -1.2%
52-week high $17.84$36.28 $779.14
52-week low $8.04$16.65 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleNTLALEGN
P/E now vs peer median -4.1xmedian 17.2x -43.3xmedian 17.2x
P/S now vs peer median 28.9xmedian 9.0x 3.1xmedian 9.0x
EV/EBITDA now vs peer median -3.1xmedian 16.3x -187.6xmedian 16.3x
P/FCF now vs peer median -4.9xmedian 18.7x -61.5xmedian 18.7x
P/B now vs peer median 2.4xmedian 2.2x 3.2xmedian 2.2x
PEG now vs peer median -0.25median 0.33 -0.92median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsNTLALEGN
Revenue $59.51M $1.27B
Gross profit – $727.10M
Operating income -$423.48M -$55.25M
Net income -$399.98M -$80.39M
Free cash flow -$348.69M -$64.60M
R&D $346.73M $396.15M
EPS (diluted) $-3.00 $-0.50
Cash & equivalents $106.13M $672.90M
Total debt – $1.06B
Shares (diluted) 133.48M 184.32M
Enterprise value -$38.77M $1.72B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricNTLALEGN
P/E -4.1x -43.3x
P/FCF -4.9x -61.5x
P/Operating cash flow -5.0x -44.5x
P/S 28.9x 3.1x
P/B 2.4x 3.2x
P/Tangible book 2.4x 3.2x
EV/EBITDA -3.1x -187.6x
EV/EBIT -3.0x -62.6x
EV/Revenue 21.5x 2.7x
EV/FCF -3.7x -53.5x
EV/Operating cash flow -3.7x -38.7x
PEG (3Y EPS CAGR) -0.25 -0.92

Growth

14 metrics
MetricNTLALEGN
Revenue growth (1Y) 12.6% 59.5%
Revenue CAGR (3Y) 3.9% 97.6%
Gross profit growth (1Y) – 42.4%
Gross profit CAGR (3Y) – 147.5%
Operating income growth (1Y) 17.3% 75.3%
Operating income CAGR (3Y) 2.7% 49.1%
Net income growth (1Y) 16.7% 75.3%
Net income CAGR (3Y) 4.1% 46.7%
EPS growth (1Y) 35.3% 72.0%
EPS CAGR (3Y) 16.5% 47.0%
Operating cash flow growth (1Y) 17.2% 67.5%
Operating cash flow CAGR (3Y) 2.0% 37.1%
Free cash flow growth (1Y) 17.3% 77.8%
Free cash flow CAGR (3Y) 3.2% 44.5%

Profitability

14 metrics
MetricNTLALEGN
Gross margin – 57.2%
EBITDA margin -696.4% -1.5%
Operating margin -711.7% -4.3%
Pretax margin -671.0% -4.4%
Net margin -672.2% -7.2%
FCF margin -586.0% -5.1%
Operating cash flow margin -582.5% -7.0%
Return on equity -59.2% -8.3%
Return on assets -49.4% -5.5%
Return on invested capital – -4.2%
Return on capital employed -58.1% -4.3%
Asset turnover 0.1x 0.8x
Cash conversion (OCF / net income) 0.9x 1.1x
Stock comp / revenue 114.1% 5.2%

Financial Health

11 metrics
MetricNTLALEGN
Debt / assets – 8.9%
Debt / equity – 0.1x
Net debt / EBITDA – 28.0x
Debt / FCF – -2.4x
Liabilities / assets 15.1% 29.8%
Equity / assets 84.9% 70.2%
Interest coverage – -4.8x
Current ratio 6.6x 3.0x
Quick ratio 5.6x 1.7x
Cash ratio 5.5x 1.7x
Altman Z-score 2.47 6.74

Shareholder Returns

7 metrics
MetricNTLALEGN
Dividend yield – –
Net buyback yield -7.7% -5.4%
Shareholder yield -7.7% -5.4%
Payout ratio (earnings) – –
Payout ratio (FCF) – –
Dividend growth (1Y) – –
Dividend CAGR (3Y) – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusNTLALEGN
EPS, next fiscal year $-3.38FY2026 $-0.04FY2026
Revenue, next fiscal year $48.94MFY2026 $1.37BFY2026
Revenue growth, next FY -27.7%FY2026 +32.9%FY2026
Revenue growth, the year after +158.6% +35.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersNTLALEGN
Held by institutions 100.0% 55.9%
Institutions holding 329 218
Change in shares held, QoQ +30.5% +7.3%
Institutions buying 195 117
Institutions selling 78 78
Buyers to sellers 2.50 1.50

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

NTLALEGN
NTLA 1.00 0.08
LEGN 0.08 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, NTLA and LEGN?

Legend Biotech (LEGN) is the largest by market capitalisation: Intellia Therapeutics (NTLA) $1.74B, Legend Biotech (LEGN) $4.22B.

Which company is growing faster?

Legend Biotech (LEGN) grew revenue fastest over the trailing twelve months: Intellia Therapeutics (NTLA) +12.6%, Legend Biotech (LEGN) +59.5%.

Which company is more profitable?

Legend Biotech (LEGN) has the highest net margin (Intellia Therapeutics (NTLA) -672.2%, Legend Biotech (LEGN) -7.2%).

Which stock has performed better?

Over the past year Intellia Therapeutics (NTLA) returned the most: Intellia Therapeutics (NTLA) -17.0%, Legend Biotech (LEGN) -32.9%. Over five years, Legend Biotech (LEGN) compounded fastest (Intellia Therapeutics (NTLA) -38.2%/yr, Legend Biotech (LEGN) -15.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Legend Biotech (LEGN) has been the steadiest (Intellia Therapeutics (NTLA) 79.8%, Legend Biotech (LEGN) 72.2%). Volatility measures how widely the price swings, not the risk of the business.

Do NTLA and LEGN move together?

Their daily returns over the past year have a correlation of 0.08, a weak relationship. Holding both diversifies more than two closely linked stocks would.

Which is the better stock, NTLA and LEGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Legend Biotech (LEGN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.