NTLA vs SLBT vs IOVA Stock Comparison

Intellia Therapeutics, SL Science Holding and Iovance Biotherapeutics Prices as of Oct 28, 2026 Peers: Industry group

Head to Head

7 decided of 12

Iovance Biotherapeutics leads on 6 of the 12 questions below (Iovance Biotherapeutics 6, Intellia Therapeutics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionNTLASLBTIOVALeader
Larger companyMarket capitalisation $1.74B $2.53B $4.32B IOVA
Cheaper on earningsLower P/E, profitable companies only -4.4x — -14.9x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months +12.6% — +34.5% IOVA
More profitableNet margin, trailing twelve months -672.2% — -89.1% IOVA
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -4.6% -88.3% +576.3% IOVA
Better 5-year returnAnnualised price return, 5 years -36.9%/yr — -9.4%/yr IOVA
Less volatileAnnualised volatility, 1 year 80.0% 175.5% 99.0% NTLA
Higher overall scoreMean of the five percentile scores vs peers 50/100 — 64/100 IOVA

Percentile Scorecard

NTLASLBTIOVA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisNTLASLBTIOVA
Valuation 34 #412 of 625 11 #556 of 625 67 #208 of 625
Growth 64 #220 of 602 – 81 #113 of 602
Profitability 39 #338 of 549 – 63 #206 of 549
Financial Health 72 #182 of 654 58 #276 of 654 64 #235 of 654
Shareholder Returns 40 #220 of 367 – 45 #204 of 367
Overall 50 – 64
  • NTLA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • SLBT ranked among 672 companies in Pharmaceuticals and Biotechnology
  • IOVA ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodNTLASLBTIOVASPY
1 month +16.6%-37.3%+34.8% +0.9%
3 months +23.3%-53.5%+224.8% +5.9%
6 months +7.1%-87.9%+347.4% +8.5%
Year to date +48.2%-88.5%+442.5% +13.3%
1 year -4.6%-88.3%+576.3% +12.4%
3 years -42.5%—+323.1% +88.1%
3 years, per year -16.8%—+61.8% +23.5%
5 years -90.0%—-39.1% +68.2%
5 years, per year -36.9%—-9.4% +11.0%
10 years +2.8%—+137.0% +263.4%
10 years, per year +0.3%—+9.0% +13.8%

Risk

MeasureNTLASLBTIOVASPY
Volatility, 1Y 80.0%175.5%99.0% 12.7%
Downside volatility, 1Y 82.2%170.6%71.1% 12.7%
Beta vs S&P 500, 1Y 2.460.231.29 1.00
Return / volatility, 1Y -0.06-0.505.82 0.98
Max drawdown, 5Y -95.5%-91.0%-93.4% -25.4%
From 52-week high -25.3%-90.6%-0.3% -0.9%
52-week high $17.84$12.81$14.86 $779.14
52-week low $8.04$1.15$1.81 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleNTLASLBTIOVA
P/E now vs peer median -4.4xmedian 17.4x —median 17.4x -23.0xmedian 17.4x
P/S now vs peer median 31.3xmedian 9.1x —median 9.1x 20.6xmedian 9.1x
EV/EBITDA now vs peer median -3.4xmedian 17.1x —median 17.1x -24.2xmedian 17.1x
P/FCF now vs peer median -5.3xmedian 19.0x -1,406xmedian 19.0x -22.6xmedian 19.0x
P/B now vs peer median 2.6xmedian 2.2x 378.4xmedian 2.2x 9.1xmedian 2.2x
PEG now vs peer median -0.27median 0.34 —median 0.34 -0.77median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsNTLASLBTIOVA
Revenue $59.51M – $324.97M
Gross profit – – $157.29M
Operating income -$423.48M – -$301.31M
Net income -$399.98M – -$289.51M
Free cash flow -$348.69M – -$296.40M
R&D $346.73M – $267.72M
EPS (diluted) $-3.00 – $-0.64
Cash & equivalents $106.13M $8.31M $110.80M
Shares (diluted) 133.48M – 450.19M
Enterprise value -$34.76M $2.52B $3.11B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricNTLASLBTIOVA
P/E -4.4x – -23.0x
P/FCF -5.3x -1,406x -22.6x
P/Operating cash flow -5.4x – -25.4x
P/S 31.3x – 20.6x
P/B 2.6x 378.4x 9.1x
P/Tangible book 2.6x 378.4x 14.2x
EV/EBITDA -3.4x – -24.2x
EV/EBIT -3.4x – -21.3x
EV/Revenue 24.0x – 19.7x
EV/FCF -4.1x – -21.6x
EV/Operating cash flow -4.1x – -24.3x
PEG (3Y EPS CAGR) -0.27 – -0.77

Growth

14 metrics
MetricNTLASLBTIOVA
Revenue growth (1Y) 12.6% – 34.5%
Revenue CAGR (3Y) 3.9% – 1,009%
Gross profit growth (1Y) – – 95.1%
Gross profit CAGR (3Y) – – –
Operating income growth (1Y) 17.3% – 26.6%
Operating income CAGR (3Y) 2.7% – 11.1%
Net income growth (1Y) 16.7% – 25.8%
Net income CAGR (3Y) 4.1% – 11.6%
EPS growth (1Y) 35.3% – 44.8%
EPS CAGR (3Y) 16.5% – 29.9%
Operating cash flow growth (1Y) 17.2% – 12.9%
Operating cash flow CAGR (3Y) 2.0% – 7.6%
Free cash flow growth (1Y) 17.3% – 8.4%
Free cash flow CAGR (3Y) 3.2% – 5.8%

Profitability

14 metrics
MetricNTLASLBTIOVA
Gross margin – – 48.4%
EBITDA margin -696.4% – -81.4%
Operating margin -711.7% – -92.7%
Pretax margin -671.0% – -90.4%
Net margin -672.2% – -89.1%
FCF margin -586.0% – -91.2%
Operating cash flow margin -582.5% – -81.3%
Return on equity -59.2% – -39.7%
Return on assets -49.4% – -31.4%
Return on invested capital – – –
Return on capital employed -58.1% – -37.0%
Asset turnover 0.1x – 0.4x
Cash conversion (OCF / net income) 0.9x – 0.9x
Stock comp / revenue 114.1% – 14.4%

Financial Health

11 metrics
MetricNTLASLBTIOVA
Debt / assets – – –
Debt / equity – – –
Net debt / EBITDA – – –
Debt / FCF – – –
Liabilities / assets 15.1% 21.8% 19.6%
Equity / assets 84.9% 78.2% 80.4%
Interest coverage – – –
Current ratio 6.6x 4.4x 4.3x
Quick ratio 5.6x 4.3x 3.7x
Cash ratio 5.5x 4.3x 2.8x
Altman Z-score 3.15 – 17.73

Shareholder Returns

7 metrics
MetricNTLASLBTIOVA
Dividend yield – – –
Net buyback yield -7.1% – -4.4%
Shareholder yield -7.1% 0.0% -4.4%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusNTLASLBTIOVA
EPS, next fiscal year $-3.38FY2026 – $-0.47FY2026
Revenue, next fiscal year $48.94MFY2026 – $434.71MFY2026
Revenue growth, next FY -27.7%FY2026 – +65.0%FY2026
Revenue growth, the year after +158.6% – +33.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersNTLASLBTIOVA
Held by institutions 100.0% – 63.3%
Institutions holding 329 – 292
Change in shares held, QoQ +30.5% – +6.5%
Institutions buying 195 – 174
Institutions selling 78 – 66
Buyers to sellers 2.50 – 2.64

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

NTLASLBTIOVA
NTLA 1.00 -0.09 0.26
SLBT -0.09 1.00 0.01
IOVA 0.26 0.01 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, NTLA, SLBT and IOVA?

Iovance Biotherapeutics (IOVA) is the largest by market capitalisation: Intellia Therapeutics (NTLA) $1.74B, SL Science Holding (SLBT) $2.53B, Iovance Biotherapeutics (IOVA) $4.32B.

Which company is growing faster?

Iovance Biotherapeutics (IOVA) grew revenue fastest over the trailing twelve months: Intellia Therapeutics (NTLA) +12.6%, Iovance Biotherapeutics (IOVA) +34.5%.

Which company is more profitable?

Iovance Biotherapeutics (IOVA) has the highest net margin (Intellia Therapeutics (NTLA) -672.2%, Iovance Biotherapeutics (IOVA) -89.1%).

Which stock has performed better?

Over the past year Iovance Biotherapeutics (IOVA) returned the most: Intellia Therapeutics (NTLA) -4.6%, SL Science Holding (SLBT) -88.3%, Iovance Biotherapeutics (IOVA) +576.3%. Over five years, Iovance Biotherapeutics (IOVA) compounded fastest (Intellia Therapeutics (NTLA) -36.9%/yr, Iovance Biotherapeutics (IOVA) -9.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Intellia Therapeutics (NTLA) has been the steadiest (Intellia Therapeutics (NTLA) 80.0%, SL Science Holding (SLBT) 175.5%, Iovance Biotherapeutics (IOVA) 99.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, NTLA, SLBT and IOVA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Iovance Biotherapeutics (IOVA) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.