NGNE vs BEAM vs SLBT Stock Comparison

Neurogene, Beam Therapeutics and SL Science Holding Prices as of Oct 27, 2026 Peers: Industry group
NGNE Neurogene Inc.
$26.99 -4.7% 1M -15.8% 1Y
Market cap
$679.94M
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
BEAM Beam Therapeutics Inc.
$24.90 +2.6% 1M -6.8% 1Y
Market cap
$2.98B
P/E
–
Revenue (TTM)
$156.04M
Div. yield
–
Gene and Cell Therapy Healthcare
5 wins

Head to Head

5 decided of 12

Beam Therapeutics leads on 5 of the 12 questions below (Beam Therapeutics 5). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionNGNEBEAMSLBTLeader
Larger companyMarket capitalisation $679.94M $2.98B $2.69B BEAM
Cheaper on earningsLower P/E, profitable companies only -6.1x -34.8x — –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months — +158.9% — –
More profitableNet margin, trailing twelve months — -54.7% — –
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — 3.0x — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -15.8% -6.8% -88.5% BEAM
Better 5-year returnAnnualised price return, 5 years -27.8%/yr -23.4%/yr — BEAM
Less volatileAnnualised volatility, 1 year 78.1% 69.2% 175.4% BEAM
Higher overall scoreMean of the five percentile scores vs peers 47/100 69/100 — BEAM

Percentile Scorecard

NGNEBEAMSLBT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisNGNEBEAMSLBT
Valuation 47 #331 of 625 54 #286 of 625 11 #555 of 625
Growth 22 #473 of 602 77 #137 of 602 –
Profitability 54 #256 of 551 64 #198 of 551 –
Financial Health 72 #185 of 656 81 #128 of 656 58 #279 of 656
Shareholder Returns 41 #216 of 365 67 #123 of 365 –
Overall 47 69 –
  • NGNE ranked among 672 companies in Pharmaceuticals and Biotechnology
  • BEAM ranked among 672 companies in Pharmaceuticals and Biotechnology
  • SLBT ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodNGNEBEAMSLBTSPY
1 month -4.7%+2.6%-24.2% -0.2%
3 months -18.8%-5.3%-56.7% +3.9%
6 months -1.7%-18.5%-84.9% +8.2%
Year to date +31.0%-10.2%-88.7% +12.9%
1 year -15.8%-6.8%-88.5% +12.3%
3 years +92.8%+33.7%— +87.4%
3 years, per year +24.5%+10.2%— +23.3%
5 years -80.3%-73.6%— +67.9%
5 years, per year -27.8%-23.4%— +10.9%
10 years -87.4%—— +261.1%
10 years, per year -18.7%—— +13.7%

Risk

MeasureNGNEBEAMSLBTSPY
Volatility, 1Y 78.1%69.2%175.4% 12.7%
Downside volatility, 1Y 76.4%63.8%170.6% 12.7%
Beta vs S&P 500, 1Y 1.562.060.23 1.00
Return / volatility, 1Y -0.20-0.10-0.50 0.97
Max drawdown, 5Y -95.3%-85.3%-91.0% -25.4%
From 52-week high -37.0%-34.3%-90.7% -1.2%
52-week high $42.84$37.92$12.81 $779.14
52-week low $16.37$20.60$1.15 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleNGNEBEAMSLBT
P/E now vs peer median -5.5xmedian 17.2x -30.4xmedian 17.2x —median 17.2x
P/S now vs peer median —median 9.0x 16.5xmedian 9.0x —median 9.0x
EV/EBITDA now vs peer median -3.2xmedian 16.3x -4.3xmedian 16.3x —median 16.3x
P/FCF now vs peer median -6.9xmedian 18.7x -6.9xmedian 18.7x -1,382xmedian 18.7x
P/B now vs peer median 2.8xmedian 2.2x 2.4xmedian 2.2x 372.2xmedian 2.2x
PEG now vs peer median -0.16median 0.33 -0.72median 0.33 —median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsNGNEBEAMSLBT
Revenue – $156.04M –
Operating income -$121.35M -$378.02M –
Net income -$111.16M -$86.52M –
Free cash flow -$87.75M -$372.77M –
R&D $88.50M $408.66M –
EPS (diluted) $-4.93 $-0.82 –
Cash & equivalents $112.49M $219.83M $8.31M
Total debt – $100.26M –
Shares (diluted) 22.55M 104.33M –
Enterprise value -$323.05M -$1.71B $2.68B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricNGNEBEAMSLBT
P/E -5.5x -30.4x –
P/FCF -6.9x -6.9x -1,382x
P/Operating cash flow -7.0x -7.2x –
P/S – 16.5x –
P/B 2.8x 2.4x 372.2x
P/Tangible book 2.8x 2.4x 372.2x
EV/EBITDA -3.2x -4.3x –
EV/EBIT -3.2x -4.0x –
EV/Revenue – 9.7x –
EV/FCF -4.4x -4.1x –
EV/Operating cash flow -4.4x -4.2x –
PEG (3Y EPS CAGR) -0.16 -0.72 –

Growth

14 metrics
MetricNGNEBEAMSLBT
Revenue growth (1Y) – 158.9% –
Revenue CAGR (3Y) – 24.9% –
Gross profit growth (1Y) – – –
Gross profit CAGR (3Y) – – –
Operating income growth (1Y) -26.8% 15.2% –
Operating income CAGR (3Y) -33.6% 0.3% –
Net income growth (1Y) -31.7% 78.2% –
Net income CAGR (3Y) -32.0% 35.8% –
EPS growth (1Y) -23.0% 79.0% –
EPS CAGR (3Y) 34.1% 42.4% –
Operating cash flow growth (1Y) -18.5% -4.2% –
Operating cash flow CAGR (3Y) -19.9% -2.0% –
Free cash flow growth (1Y) -17.8% -4.8% –
Free cash flow CAGR (3Y) -19.1% 0.7% –

Profitability

14 metrics
MetricNGNEBEAMSLBT
Gross margin – – –
EBITDA margin – -228.0% –
Operating margin – -242.3% –
Pretax margin – -54.4% –
Net margin – -54.7% –
FCF margin – -238.9% –
Operating cash flow margin – -230.3% –
Return on equity -49.1% -7.6% –
Return on assets -44.0% -5.9% –
Return on invested capital – – –
Return on capital employed -52.2% -27.9% –
Asset turnover – 0.1x –
Cash conversion (OCF / net income) 0.8x 4.2x –
Stock comp / revenue – 52.2% –

Financial Health

11 metrics
MetricNGNEBEAMSLBT
Debt / assets – 7.2% –
Debt / equity – 0.1x –
Net debt / EBITDA – 3.0x –
Debt / FCF – -0.3x –
Liabilities / assets 11.1% 23.0% 21.8%
Equity / assets 88.9% 77.0% 78.2%
Interest coverage -60,673x – –
Current ratio 10.6x 14.6x 4.4x
Quick ratio 10.5x 14.3x 4.3x
Cash ratio 10.5x 14.3x 4.3x
Altman Z-score – 3.08 –

Shareholder Returns

7 metrics
MetricNGNEBEAMSLBT
Dividend yield – – –
Net buyback yield -6.1% -0.6% –
Shareholder yield -6.1% -0.6% 0.0%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusNGNEBEAMSLBT
EPS, next fiscal year $-5.76FY2026 $-4.22FY2026 –
Revenue, next fiscal year $0.00FY2026 $49.46MFY2026 –
Revenue growth, next FY – -64.6%FY2026 –
Revenue growth, the year after – +23.6% –

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersNGNEBEAMSLBT
Held by institutions 76.8% 100.0% –
Institutions holding 113 277 –
Change in shares held, QoQ +2.0% +1.0% –
Institutions buying 61 154 –
Institutions selling 31 75 –
Buyers to sellers 1.97 2.05 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

NGNEBEAMSLBT
NGNE 1.00 0.33 -0.03
BEAM 0.33 1.00 0.00
SLBT -0.03 0.00 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, NGNE, BEAM and SLBT?

Beam Therapeutics (BEAM) is the largest by market capitalisation: Neurogene (NGNE) $679.94M, Beam Therapeutics (BEAM) $2.98B, SL Science Holding (SLBT) $2.69B.

Which stock has performed better?

Over the past year Beam Therapeutics (BEAM) returned the most: Neurogene (NGNE) -15.8%, Beam Therapeutics (BEAM) -6.8%, SL Science Holding (SLBT) -88.5%. Over five years, Beam Therapeutics (BEAM) compounded fastest (Neurogene (NGNE) -27.8%/yr, Beam Therapeutics (BEAM) -23.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Beam Therapeutics (BEAM) has been the steadiest (Neurogene (NGNE) 78.1%, Beam Therapeutics (BEAM) 69.2%, SL Science Holding (SLBT) 175.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, NGNE, BEAM and SLBT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Beam Therapeutics (BEAM) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.