MRK vs PFE vs NVS Stock Comparison

Merck, Pfizer and Novartis Ag Prices as of Nov 2, 2026 Peers: Industry group
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MRK Merck & Co., Inc.
$148.49 +2.9% 1M +72.7% 1Y
Market cap
$366.35B
P/E
115.6x
Revenue (TTM)
$66.57B
Div. yield
2.29%
Pharmaceuticals Healthcare
3 wins
PFE Pfizer Inc
$30.71 +10.5% 1M +24.6% 1Y
Market cap
$175.04B
P/E
40.4x
Revenue (TTM)
$63.70B
Div. yield
5.60%
Pharmaceuticals Healthcare
7 wins
NVS Novartis Ag
$161.48 +14.5% 1M +30.4% 1Y
Market cap
$308.13B
P/E
17.9x
Revenue (TTM)
—
Div. yield
2.94%
Pharmaceuticals Healthcare
2 wins

Head to Head

12 decided of 12

Pfizer leads on 7 of the 12 questions below (Pfizer 7, Merck 3, Novartis Ag 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionMRKPFENVSLeader
Larger companyMarket capitalisation $366.35B $175.04B $308.13B MRK
Cheaper on earningsLower P/E, profitable companies only 115.6x 40.4x 17.9x NVS
Cheaper on forward earningsLower price / next fiscal year consensus EPS 59.9x 10.8x 17.4x PFE
Faster revenue growthRevenue growth, trailing twelve months +4.6% -0.2% — MRK
More profitableNet margin, trailing twelve months 4.8% 6.8% — PFE
Better return on capitalReturn on invested capital 3.6% 13.4% — PFE
Less leveragedLower net debt / EBITDA 3.6x 1.9x — PFE
Higher dividend yieldTrailing dividend yield 2.29% 5.60% 2.94% PFE
Better 1-year returnPrice return, last 12 months +72.7% +24.6% +30.4% MRK
Better 5-year returnAnnualised price return, 5 years +10.9%/yr -7.3%/yr +14.1%/yr NVS
Less volatileAnnualised volatility, 1 year 29.6% 21.7% 27.6% PFE
Higher overall scoreMean of the five percentile scores vs peers 62/100 65/100 — PFE

Percentile Scorecard

MRKPFENVS

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisMRKPFENVS
Valuation 79 #130 of 623 94 #37 of 623 97 #20 of 623
Growth 37 #380 of 601 24 #460 of 601 –
Profitability 91 #53 of 553 92 #46 of 553 –
Financial Health 21 #519 of 654 25 #493 of 654 –
Shareholder Returns 80 #73 of 367 90 #38 of 367 80 #75 of 367
Overall 62 65 –
  • MRK ranked among 671 companies in Pharmaceuticals and Biotechnology
  • PFE ranked among 671 companies in Pharmaceuticals and Biotechnology
  • NVS ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodMRKPFENVSSPY
1 month +2.9%+10.5%+14.5% -2.3%
3 months +16.2%+22.6%+5.1% -0.7%
6 months +31.3%+16.8%+11.7% +4.8%
Year to date +41.1%+23.3%+17.1% +10.3%
1 year +72.7%+24.6%+30.4% +10.3%
3 years +43.6%-1.8%+74.1% +73.0%
3 years, per year +12.8%-0.6%+20.3% +20.1%
5 years +67.4%-31.5%+93.2% +61.9%
5 years, per year +10.9%-7.3%+14.1% +10.1%
10 years +152.4%+0.3%+126.6% +258.6%
10 years, per year +9.7%+0.0%+8.5% +13.6%

Risk

MeasureMRKPFENVSSPY
Volatility, 1Y 29.6%21.7%27.6% 12.8%
Downside volatility, 1Y 24.1%21.1%30.1% 12.8%
Beta vs S&P 500, 1Y 0.090.200.34 1.00
Return / volatility, 1Y 2.461.131.10 0.80
Max drawdown, 5Y -44.7%-64.8%-20.4% -25.4%
From 52-week high -5.1%0.0%-4.2% -3.5%
52-week high $156.45$30.71$168.62 $779.14
52-week low $82.49$23.67$123.86 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleMRKPFENVS
P/E now vs peer median 115.6xmedian 17.4x 40.4xmedian 17.4x 17.9xmedian 17.4x
P/S now vs peer median 5.5xmedian 8.9x 2.7xmedian 8.9x 5.1xmedian 8.9x
EV/EBITDA now vs peer median 31.5xmedian 17.0x 8.4xmedian 17.0x —median 17.0x
P/FCF now vs peer median 22.8xmedian 21.4x 15.9xmedian 21.4x 14.3xmedian 21.4x
P/B now vs peer median 8.7xmedian 2.1x 2.0xmedian 2.1x —median 2.1x
PEG now vs peer median 72.76median 0.35 -0.98median 0.35 —median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsMRKPFENVS
Revenue $66.57B $63.70B –
Gross profit $48.57B $46.61B –
Operating income $6.38B $20.39B –
Net income $3.17B $4.36B –
Free cash flow $16.06B $10.99B –
R&D $30.45B $11.05B –
EPS (diluted) $1.28 $0.76 –
Cash & equivalents $6.85B $976.00M $400.00M
Total debt $53.91B $63.19B –
Shares (diluted) 2.47B 5.70B 1.96B
Enterprise value $320.78B $121.98B $281.70B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricMRKPFENVS
P/E 115.6x 40.4x 17.9x
P/FCF 22.8x 15.9x 14.3x
P/Operating cash flow 18.3x 13.1x –
P/S 5.5x 2.7x 5.1x
P/B 8.7x 2.0x –
P/Tangible book 21.5x 4.6x –
EV/EBITDA 31.5x 8.4x –
EV/EBIT 64.8x 11.1x –
EV/Revenue 6.2x 3.6x –
EV/FCF 25.7x 20.6x –
EV/Operating cash flow 20.7x 16.9x –
PEG (3Y EPS CAGR) 72.76 -0.98 –

Growth

14 metrics
MetricMRKPFENVS
Revenue growth (1Y) 4.6% -0.2% –
Revenue CAGR (3Y) 4.5% -7.0% –
Gross profit growth (1Y) -0.3% 1.2% –
Gross profit CAGR (3Y) 4.5% -5.6% –
Operating income growth (1Y) -66.6% 1.5% –
Operating income CAGR (3Y) 1.9% -9.9% –
Net income growth (1Y) -80.7% -59.6% –
Net income CAGR (3Y) 0.5% -41.3% –
EPS growth (1Y) -80.3% -59.7% –
EPS CAGR (3Y) 1.6% -41.3% –
Operating cash flow growth (1Y) 7.7% -11.8% –
Operating cash flow CAGR (3Y) 9.8% -2.7% –
Free cash flow growth (1Y) 9.1% -11.7% –
Free cash flow CAGR (3Y) 14.0% 1.0% –

Profitability

14 metrics
MetricMRKPFENVS
Gross margin 73.0% 73.2% –
EBITDA margin 19.7% 42.4% –
Operating margin 9.6% 32.0% –
Pretax margin 8.9% 6.6% –
Net margin 4.8% 6.8% –
FCF margin 24.1% 17.2% –
Operating cash flow margin 30.0% 21.0% –
Return on equity 7.2% 5.0% –
Return on assets 2.5% 2.1% –
Return on invested capital 3.6% 13.4% –
Return on capital employed 6.3% 11.9% –
Asset turnover 0.5x 0.3x –
Cash conversion (OCF / net income) 6.3x 3.1x –
Stock comp / revenue 1.3% 1.5% –

Financial Health

11 metrics
MetricMRKPFENVS
Debt / assets 41.5% 31.4% –
Debt / equity 1.3x 0.7x –
Net debt / EBITDA 3.6x 1.9x –
Debt / FCF 3.4x 5.8x –
Liabilities / assets 67.7% 57.5% –
Equity / assets 32.3% 42.5% –
Interest coverage – – –
Current ratio 1.3x 1.3x –
Quick ratio 0.7x 0.7x –
Cash ratio 0.3x 0.4x –
Altman Z-score 3.94 2.39 –

Shareholder Returns

7 metrics
MetricMRKPFENVS
Dividend yield 2.3% 5.6% 2.9%
Net buyback yield 1.1% – –
Shareholder yield 3.4% 5.6% 2.9%
Payout ratio (earnings) 261.8% 224.5% –
Payout ratio (FCF) 51.7% 89.1% –
Dividend growth (1Y) 3.3% 1.5% –
Dividend CAGR (3Y) 4.7% 2.4% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusMRKPFENVS
Forward P/E 59.9xFY2026 10.8xFY2026 17.4xFY2026
EPS, next fiscal year $2.48FY2026 $2.85FY2026 $9.26FY2026
EPS growth, next FY -72.4%FY2026 -11.5%FY2026 +3.1%FY2026
EPS growth, the year after +257.3% -4.6% +1.2%
Revenue, next fiscal year $69.45BFY2026 $60.59BFY2026 $53.95BFY2026
Revenue growth, next FY +6.8%FY2026 -3.2%FY2026 -1.1%FY2026
Revenue growth, the year after -3.8% +3.9% +19.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersMRKPFENVS
Held by institutions 79.9% 66.9% 7.0%
Institutions holding 3,799 2,838 1,609
Change in shares held, QoQ +2.6% +2.0% -5.9%
Institutions buying 1,843 1,326 662
Institutions selling 1,466 1,205 562
Buyers to sellers 1.26 1.10 1.18

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

MRKPFENVS
MRK 1.00 0.46 0.47
PFE 0.46 1.00 0.49
NVS 0.47 0.49 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, MRK, PFE and NVS?

Merck (MRK) is the largest by market capitalisation: Merck (MRK) $366.35B, Pfizer (PFE) $175.04B, Novartis Ag (NVS) $308.13B.

Which stock is cheaper, MRK, PFE and NVS?

Novartis Ag (NVS) trades on the lowest price-to-earnings ratio (Merck (MRK) 115.6x, Pfizer (PFE) 40.4x, Novartis Ag (NVS) 17.9x). On next year's consensus earnings, Pfizer (PFE) is cheapest (Merck (MRK) 59.9x, Pfizer (PFE) 10.8x, Novartis Ag (NVS) 17.4x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Merck (MRK) grew revenue fastest over the trailing twelve months: Merck (MRK) +4.6%, Pfizer (PFE) -0.2%.

Which company is more profitable?

Pfizer (PFE) has the highest net margin (Merck (MRK) 4.8%, Pfizer (PFE) 6.8%). On return on invested capital, Pfizer (PFE) leads (Merck (MRK) 3.6%, Pfizer (PFE) 13.4%).

Which stock has performed better?

Over the past year Merck (MRK) returned the most: Merck (MRK) +72.7%, Pfizer (PFE) +24.6%, Novartis Ag (NVS) +30.4%. Over five years, Novartis Ag (NVS) compounded fastest (Merck (MRK) +10.9%/yr, Pfizer (PFE) -7.3%/yr, Novartis Ag (NVS) +14.1%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Pfizer (PFE) has the highest dividend yield: Merck (MRK) 2.29%, Pfizer (PFE) 5.60%, Novartis Ag (NVS) 2.94%.

Which stock is riskier?

By one-year price volatility, Pfizer (PFE) has been the steadiest (Merck (MRK) 29.6%, Pfizer (PFE) 21.7%, Novartis Ag (NVS) 27.6%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, MRK, PFE and NVS?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Pfizer (PFE) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.