MDT vs PEN vs ISRG Stock Comparison

Medtronic, Penumbra and Intuitive Surgical Prices as of Nov 5, 2026 Peers: Industry group
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MDT Medtronic plc
$104.83 +20.4% 1M +16.0% 1Y
Market cap
$134.19B
P/E
25.6x
Revenue (TTM)
$37.54B
Div. yield
2.73%
Medical Devices Healthcare
2 wins
PEN Penumbra Inc
$321.18 +1.3% 1M +42.4% 1Y
Market cap
$12.66B
P/E
80.6x
Revenue (TTM)
$1.56B
Div. yield
–
Medical Devices Healthcare
2 wins
ISRG Intuitive Surgical Inc
$468.52 +15.8% 1M -14.6% 1Y
Market cap
$162.39B
P/E
55.3x
Revenue (TTM)
$11.58B
Div. yield
–
Medical Devices Healthcare
5 wins

Head to Head

9 decided of 12

Intuitive Surgical leads on 5 of the 12 questions below (Intuitive Surgical 5, Medtronic 2, Penumbra 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionMDTPENISRGLeader
Larger companyMarket capitalisation $134.19B $12.66B $162.39B ISRG
Cheaper on earningsLower P/E, profitable companies only 25.6x 80.6x 55.3x MDT
Cheaper on forward earningsLower price / next fiscal year consensus EPS 18.8x 73.0x 40.7x MDT
Faster revenue growthRevenue growth, trailing twelve months +9.8% +17.0% +20.5% ISRG
More profitableNet margin, trailing twelve months 13.9% 10.1% 25.5% ISRG
Better return on capitalReturn on invested capital 6.9% — — –
Less leveragedLower net debt / EBITDA 2.0x — — –
Higher dividend yieldTrailing dividend yield 2.73% — — –
Better 1-year returnPrice return, last 12 months +16.0% +42.4% -14.6% PEN
Better 5-year returnAnnualised price return, 5 years -3.1%/yr +2.4%/yr +5.1%/yr ISRG
Less volatileAnnualised volatility, 1 year 25.6% 25.2% 35.9% PEN
Higher overall scoreMean of the five percentile scores vs peers 64/100 74/100 79/100 ISRG

Percentile Scorecard

MDTPENISRG

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisMDTPENISRG
Valuation 80 #47 of 229 52 #111 of 229 47 #123 of 229
Growth 50 #112 of 221 87 #29 of 221 81 #44 of 221
Profitability 88 #26 of 210 85 #32 of 210 97 #7 of 210
Financial Health 50 #120 of 240 88 #30 of 240 81 #47 of 240
Shareholder Returns 54 #68 of 147 56 #65 of 147 93 #12 of 147
Overall 64 74 79
  • MDT ranked among 247 companies in Medical Devices and Diagnostics
  • PEN ranked among 247 companies in Medical Devices and Diagnostics
  • ISRG ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodMDTPENISRGSPY
1 month +20.4%+1.3%+15.8% -5.9%
3 months +22.0%-1.1%+25.4% -4.6%
6 months +34.5%-1.1%+3.3% +0.2%
Year to date +9.1%+3.3%-17.3% +7.5%
1 year +16.0%+42.4%-14.6% +8.2%
3 years +42.8%+61.6%+69.0% +68.3%
3 years, per year +12.6%+17.4%+19.1% +19.0%
5 years -14.8%+12.6%+28.4% +56.5%
5 years, per year -3.1%+2.4%+5.1% +9.4%
10 years +27.6%+434.9%+528.0% +251.5%
10 years, per year +2.5%+18.3%+20.2% +13.4%

Risk

MeasureMDTPENISRGSPY
Volatility, 1Y 25.6%25.2%35.9% 13.6%
Downside volatility, 1Y 22.0%15.1%38.0% 14.2%
Beta vs S&P 500, 1Y 0.140.110.93 1.00
Return / volatility, 1Y 0.621.68-0.41 0.60
Max drawdown, 5Y -43.6%-59.6%-49.9% -25.4%
From 52-week high -0.5%-10.6%-21.0% -5.9%
52-week high $105.35$359.40$592.85 $779.14
52-week low $73.75$225.54$332.02 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleMDTPENISRG
P/E now vs peer median 25.6xmedian 26.9x 80.6xmedian 26.9x 55.3xmedian 26.9x
P/S now vs peer median 3.6xmedian 2.9x 8.1xmedian 2.9x 14.0xmedian 2.9x
EV/EBITDA now vs peer median 15.8xmedian 17.5x 57.2xmedian 17.5x 38.7xmedian 17.5x
P/FCF now vs peer median 21.9xmedian 26.4x 63.2xmedian 26.4x 45.1xmedian 26.4x
P/B now vs peer median 2.6xmedian 2.3x 8.0xmedian 2.3x 10.1xmedian 2.3x
PEG now vs peer median 1.77median 0.88 1.43median 0.88 2.15median 0.88

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsMDTPENISRG
Revenue $37.54B $1.56B $11.58B
Gross profit $24.41B $1.06B $7.78B
Operating income $6.79B $189.25M $3.28B
Net income $5.27B $157.02M $2.97B
Free cash flow $6.13B $200.29M $3.60B
R&D $2.92B $94.93M $1.49B
EPS (diluted) $4.07 $3.96 $8.41
Cash & equivalents $1.69B $254.28M $2.98B
Total debt $28.15B – –
Shares (diluted) 1.29B 39.62M 351.60M
Enterprise value $100.06B $10.17B $142.81B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricMDTPENISRG
P/E 25.6x 80.6x 55.3x
P/FCF 21.9x 63.2x 45.1x
P/Operating cash flow 16.7x 48.5x 39.7x
P/S 3.6x 8.1x 14.0x
P/B 2.6x 8.0x 10.1x
P/Tangible book 3.3x 8.0x 10.9x
EV/EBITDA 15.8x 57.2x 38.7x
EV/EBIT 22.6x 63.3x 48.2x
EV/Revenue 4.1x 7.7x 13.7x
EV/FCF 25.0x 59.8x 44.0x
EV/Operating cash flow 19.1x 45.9x 38.7x
PEG (3Y EPS CAGR) 1.77 1.43 2.15

Growth

14 metrics
MetricMDTPENISRG
Revenue growth (1Y) 9.8% 17.0% 20.5%
Revenue CAGR (3Y) 6.0% 16.2% 19.1%
Gross profit growth (1Y) 9.3% 19.1% 21.9%
Gross profit CAGR (3Y) 5.6% 18.7% 19.5%
Operating income growth (1Y) 10.9% 9.5% 16.6%
Operating income CAGR (3Y) 6.4% 63.4% 24.8%
Net income growth (1Y) 12.4% -4.3% 7.5%
Net income CAGR (3Y) 13.0% 56.9% 24.4%
EPS growth (1Y) 12.4% -5.0% 10.8%
EPS CAGR (3Y) 14.5% 56.4% 25.7%
Operating cash flow growth (1Y) 12.4% 28.4% 38.1%
Operating cash flow CAGR (3Y) 11.3% 61.1% 26.4%
Free cash flow growth (1Y) 15.6% 31.2% 58.4%
Free cash flow CAGR (3Y) 11.3% 61.8% 42.0%

Profitability

14 metrics
MetricMDTPENISRG
Gross margin 65.0% 68.0% 67.2%
EBITDA margin 25.9% 13.4% 35.3%
Operating margin 18.1% 12.1% 28.4%
Pretax margin 17.6% 13.3% 31.3%
Net margin 13.9% 10.1% 25.5%
FCF margin 16.3% 12.8% 31.1%
Operating cash flow margin 21.4% 16.7% 35.3%
Return on equity 10.4% 10.1% 17.3%
Return on assets 5.7% 7.8% 14.8%
Return on invested capital 6.9% – –
Return on capital employed 8.3% 10.7% 18.7%
Asset turnover 0.4x 0.8x 0.6x
Cash conversion (OCF / net income) 1.5x 1.7x 1.4x
Stock comp / revenue 1.3% 3.7% 7.2%

Financial Health

11 metrics
MetricMDTPENISRG
Debt / assets 30.2% – –
Debt / equity 0.6x – –
Net debt / EBITDA 2.0x – –
Debt / FCF 4.6x – –
Liabilities / assets 45.5% 21.8% 16.7%
Equity / assets 54.5% 78.2% 83.3%
Interest coverage 9.4x – –
Current ratio 2.1x 5.9x 3.3x
Quick ratio 1.3x 3.7x 2.3x
Cash ratio 0.7x 2.9x 1.6x
Altman Z-score 3.20 19.20 32.00

Shareholder Returns

7 metrics
MetricMDTPENISRG
Dividend yield 2.7% – –
Net buyback yield 0.1% -0.1% 2.6%
Shareholder yield 2.9% -0.1% 2.6%
Payout ratio (earnings) 69.3% – –
Payout ratio (FCF) 59.5% – –
Dividend growth (1Y) 1.4% – –
Dividend CAGR (3Y) 0.2% – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusMDTPENISRG
Forward P/E 18.8xFY2026 73.0xFY2026 40.7xFY2026
EPS, next fiscal year $5.57FY2026 $4.40FY2026 $11.51FY2026
EPS growth, next FY +0.7%FY2026 +14.6%FY2026 +28.9%FY2026
EPS growth, the year after +7.2% +43.9% +4.5%
Revenue, next fiscal year $39.92BFY2026 $1.64BFY2026 $11.61BFY2026
Revenue growth, next FY +9.8%FY2026 +17.0%FY2026 +15.4%FY2026
Revenue growth, the year after -4.7% +7.4% +11.2%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersMDTPENISRG
Held by institutions 85.1% 86.6% 86.2%
Institutions holding 2,127 451 2,240
Change in shares held, QoQ -0.2% +0.9% +4.6%
Institutions buying 1,014 195 1,072
Institutions selling 915 182 879
Buyers to sellers 1.11 1.07 1.22

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

MDTPENISRG
MDT 1.00 0.29 0.47
PEN 0.29 1.00 0.19
ISRG 0.47 0.19 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, MDT, PEN and ISRG?

Intuitive Surgical (ISRG) is the largest by market capitalisation: Medtronic (MDT) $134.19B, Penumbra (PEN) $12.66B, Intuitive Surgical (ISRG) $162.39B.

Which stock is cheaper, MDT, PEN and ISRG?

Medtronic (MDT) trades on the lowest price-to-earnings ratio (Medtronic (MDT) 25.6x, Penumbra (PEN) 80.6x, Intuitive Surgical (ISRG) 55.3x). On next year's consensus earnings, Medtronic (MDT) is cheapest (Medtronic (MDT) 18.8x, Penumbra (PEN) 73.0x, Intuitive Surgical (ISRG) 40.7x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Intuitive Surgical (ISRG) grew revenue fastest over the trailing twelve months: Medtronic (MDT) +9.8%, Penumbra (PEN) +17.0%, Intuitive Surgical (ISRG) +20.5%.

Which company is more profitable?

Intuitive Surgical (ISRG) has the highest net margin (Medtronic (MDT) 13.9%, Penumbra (PEN) 10.1%, Intuitive Surgical (ISRG) 25.5%).

Which stock has performed better?

Over the past year Penumbra (PEN) returned the most: Medtronic (MDT) +16.0%, Penumbra (PEN) +42.4%, Intuitive Surgical (ISRG) -14.6%. Over five years, Intuitive Surgical (ISRG) compounded fastest (Medtronic (MDT) -3.1%/yr, Penumbra (PEN) +2.4%/yr, Intuitive Surgical (ISRG) +5.1%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Medtronic (MDT) 2.73%. Penumbra (PEN) and Intuitive Surgical (ISRG) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Penumbra (PEN) has been the steadiest (Medtronic (MDT) 25.6%, Penumbra (PEN) 25.2%, Intuitive Surgical (ISRG) 35.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, MDT, PEN and ISRG?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Intuitive Surgical (ISRG) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.