MDLN vs ISRG vs SKYA Stock Comparison

Medline, Intuitive Surgical and SkyAI Prices as of Nov 5, 2026 Peers: Industry group
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MDLN Medline Inc.
$39.76 +11.8% 1M
Market cap
$34.66B
P/E
60.1x
Revenue (TTM)
$30.68B
Div. yield
–
Medical Supplies Healthcare
ISRG Intuitive Surgical Inc
$468.52 +15.8% 1M -14.6% 1Y
Market cap
$158.98B
P/E
53.8x
Revenue (TTM)
$11.58B
Div. yield
–
Medical Devices Healthcare
6 wins
SKYA SkyAI, Inc.
$2.92 +55.3% 1M -30.6% 1Y
Market cap
$212.68M
P/E
–
Revenue (TTM)
$174.18K
Div. yield
–
Medical Supplies Healthcare
2 wins

Head to Head

8 decided of 12

Intuitive Surgical leads on 6 of the 12 questions below (Intuitive Surgical 6, SkyAI 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionMDLNISRGSKYALeader
Larger companyMarket capitalisation $34.66B $158.98B $212.68M ISRG
Cheaper on earningsLower P/E, profitable companies only 60.1x 53.8x -0.5x ISRG
Cheaper on forward earningsLower price / next fiscal year consensus EPS 27.6x 40.7x 0.0x SKYA
Faster revenue growthRevenue growth, trailing twelve months — +20.5% +108.0% SKYA
More profitableNet margin, trailing twelve months 1.9% 25.5% -228,220.7% ISRG
Better return on capitalReturn on invested capital 4.3% — — –
Less leveragedLower net debt / EBITDA 3.2x — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months — -14.6% -30.6% ISRG
Better 5-year returnAnnualised price return, 5 years — +5.1%/yr — –
Less volatileAnnualised volatility, 1 year 47.8% 35.9% 104.7% ISRG
Higher overall scoreMean of the five percentile scores vs peers 52/100 79/100 27/100 ISRG

Percentile Scorecard

MDLNISRGSKYA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisMDLNISRGSKYA
Valuation 79 #49 of 229 47 #123 of 229 4 #221 of 229
Growth – 81 #44 of 221 4 #213 of 221
Profitability 73 #58 of 210 97 #7 of 210 1 #209 of 210
Financial Health 43 #137 of 240 81 #47 of 240 95 #13 of 240
Shareholder Returns 14 #126 of 147 93 #12 of 147 33 #99 of 147
Overall 52 79 27
  • MDLN ranked among 247 companies in Medical Devices and Diagnostics
  • ISRG ranked among 247 companies in Medical Devices and Diagnostics
  • SKYA ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodMDLNISRGSKYASPY
1 month +11.8%+15.8%+55.3% -5.9%
3 months +15.2%+25.4%+149.6% -4.6%
6 months -5.0%+3.3%+56.1% +0.2%
Year to date -5.3%-17.3%+43.8% +7.5%
1 year —-14.6%-30.6% +8.2%
3 years —+69.0%-99.9% +68.3%
3 years, per year —+19.1%-90.0% +19.0%
5 years —+28.4%— +56.5%
5 years, per year —+5.1%— +9.4%
10 years —+528.0%— +251.5%
10 years, per year —+20.2%— +13.4%

Risk

MeasureMDLNISRGSKYASPY
Volatility, 1Y 47.8%35.9%104.7% 13.6%
Downside volatility, 1Y 48.1%38.0%104.1% 14.2%
Beta vs S&P 500, 1Y 0.690.932.15 1.00
Return / volatility, 1Y —-0.41-0.29 0.60
Max drawdown, 5Y -36.7%-49.9%-100.0% -25.4%
From 52-week high -20.5%-21.0%-30.6% -5.9%
52-week high $49.99$592.85$4.21 $779.14
52-week low $31.64$332.02$0.95 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleMDLNISRGSKYA
P/E now vs peer median 60.4xmedian 26.9x 55.3xmedian 26.9x -0.5xmedian 26.9x
P/S now vs peer median 1.7xmedian 2.9x 14.0xmedian 2.9x 1,209xmedian 2.9x
EV/EBITDA now vs peer median 21.7xmedian 17.5x 38.7xmedian 17.5x -0.5xmedian 17.5x
P/FCF now vs peer median 27.6xmedian 26.4x 45.1xmedian 26.4x -1.0xmedian 26.4x
P/B now vs peer median 2.7xmedian 2.3x 10.1xmedian 2.3x 1.3xmedian 2.3x
PEG now vs peer median —median 0.88 2.15median 0.88 0.01median 0.88

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsMDLNISRGSKYA
Revenue $30.68B $11.58B $174.18K
Gross profit $7.90B $7.78B $324.68K
Operating income $1.74B $3.28B -$374.36M
Net income $889.00M $2.97B -$397.51M
Free cash flow $1.90B $3.60B -$201.93M
R&D – $1.49B $475.55K
EPS (diluted) $0.44 $8.41 $-5.51
Cash & equivalents $2.32B $2.98B $12.07M
Total debt $12.58B – –
Shares (diluted) 1.32B 351.60M 72.09M
Enterprise value $24.20B $139.27B $167.38M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricMDLNISRGSKYA
P/E 60.4x 55.3x -0.5x
P/FCF 27.6x 45.1x -1.0x
P/Operating cash flow 22.0x 39.7x -14.6x
P/S 1.7x 14.0x 1,209x
P/B 2.7x 10.1x 1.3x
P/Tangible book 8.7x 10.9x 16.2x
EV/EBITDA 21.7x 38.7x -0.5x
EV/EBIT 35.2x 48.2x -0.5x
EV/Revenue 2.0x 13.7x 1,139x
EV/FCF 32.3x 44.0x -1.0x
EV/Operating cash flow 25.7x 38.7x -13.8x
PEG (3Y EPS CAGR) – 2.15 0.01

Growth

14 metrics
MetricMDLNISRGSKYA
Revenue growth (1Y) – 20.5% 108.0%
Revenue CAGR (3Y) – 19.1% 19.4%
Gross profit growth (1Y) – 21.9% –
Gross profit CAGR (3Y) – 19.5% –
Operating income growth (1Y) – 16.6% -8,055%
Operating income CAGR (3Y) – 24.8% -240.7%
Net income growth (1Y) – 7.5% -54,854%
Net income CAGR (3Y) – 24.4% -268.2%
EPS growth (1Y) – 10.8% -658.6%
EPS CAGR (3Y) – 25.7% -100.6%
Operating cash flow growth (1Y) – 38.1% -356.8%
Operating cash flow CAGR (3Y) – 26.4% -24.4%
Free cash flow growth (1Y) – 58.4% -6,031%
Free cash flow CAGR (3Y) – 42.0% -196.9%

Profitability

14 metrics
MetricMDLNISRGSKYA
Gross margin 25.7% 67.2% 186.4%
EBITDA margin 9.2% 35.3% -214,892%
Operating margin 5.7% 28.4% -214,931%
Pretax margin 3.6% 31.3% -221,236%
Net margin 1.9% 25.5% -228,221%
FCF margin 6.2% 31.1% -115,934%
Operating cash flow margin 7.8% 35.3% -8,259%
Return on equity 4.6% 17.3% -280.7%
Return on assets 2.2% 14.8% -276.3%
Return on invested capital 4.3% – –
Return on capital employed 4.8% 18.7% -223.1%
Asset turnover 0.8x 0.6x 0.0x
Cash conversion (OCF / net income) 2.7x 1.4x 0.0x
Stock comp / revenue 0.4% 7.2% 52,451%

Financial Health

11 metrics
MetricMDLNISRGSKYA
Debt / assets 31.3% – –
Debt / equity 0.6x – –
Net debt / EBITDA 3.2x – –
Debt / FCF 6.6x – –
Liabilities / assets 51.7% 16.7% 1.9%
Equity / assets 48.3% 83.3% 98.1%
Interest coverage – – –
Current ratio 4.0x 3.3x 5.3x
Quick ratio 2.4x 2.3x 4.4x
Cash ratio 1.2x 1.6x 4.2x
Altman Z-score 2.71 32.00 29.80

Shareholder Returns

7 metrics
MetricMDLNISRGSKYA
Dividend yield – – –
Net buyback yield -13.5% 2.6% -0.6%
Shareholder yield -13.5% 2.6% -0.6%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusMDLNISRGSKYA
Forward P/E 27.6xFY2026 40.7xFY2026 0.0xFY2026
EPS, next fiscal year $1.44FY2026 $11.51FY2026 $2,362.06FY2026
EPS growth, next FY +0.7%FY2026 +28.9%FY2026 –
EPS growth, the year after +13.9% +4.5% –
Revenue, next fiscal year $32.52BFY2026 $11.61BFY2026 $70.01MFY2026
Revenue growth, next FY +14.4%FY2026 +15.4%FY2026 +34,200.1%FY2026
Revenue growth, the year after +8.0% +11.2% +17.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersMDLNISRGSKYA
Held by institutions 57.1% 86.2% –
Institutions holding 409 2,240 –
Change in shares held, QoQ +17.9% +4.6% –
Institutions buying 322 1,072 –
Institutions selling 69 879 –
Buyers to sellers 4.67 1.22 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

MDLNISRGSKYA
MDLN 1.00 0.31 0.05
ISRG 0.31 1.00 0.14
SKYA 0.05 0.14 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, MDLN, ISRG and SKYA?

Intuitive Surgical (ISRG) is the largest by market capitalisation: Medline (MDLN) $34.66B, Intuitive Surgical (ISRG) $158.98B, SkyAI (SKYA) $212.68M.

Which stock is cheaper, MDLN, ISRG and SKYA?

Intuitive Surgical (ISRG) trades on the lowest price-to-earnings ratio (Medline (MDLN) 60.1x, Intuitive Surgical (ISRG) 53.8x, SkyAI (SKYA) -0.5x). On next year's consensus earnings, SkyAI (SKYA) is cheapest (Medline (MDLN) 27.6x, Intuitive Surgical (ISRG) 40.7x, SkyAI (SKYA) 0.0x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

SkyAI (SKYA) grew revenue fastest over the trailing twelve months: Intuitive Surgical (ISRG) +20.5%, SkyAI (SKYA) +108.0%.

Which company is more profitable?

Intuitive Surgical (ISRG) has the highest net margin (Medline (MDLN) 1.9%, Intuitive Surgical (ISRG) 25.5%, SkyAI (SKYA) -228,220.7%).

Which stock has performed better?

Over the past year Intuitive Surgical (ISRG) returned the most: Intuitive Surgical (ISRG) -14.6%, SkyAI (SKYA) -30.6%. Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Intuitive Surgical (ISRG) has been the steadiest (Medline (MDLN) 47.8%, Intuitive Surgical (ISRG) 35.9%, SkyAI (SKYA) 104.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, MDLN, ISRG and SKYA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Intuitive Surgical (ISRG) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.