MDGL vs MRNA vs NXTS Stock Comparison

Madrigal Pharmaceuticals, Moderna and Nexentis Technologies Prices as of Oct 27, 2026 Peers: Industry group
MRNA Moderna, Inc.
$207.97 +4.6% 1M +680.1% 1Y
Market cap
$82.98B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
3 wins

Head to Head

8 decided of 12

Madrigal Pharmaceuticals leads on 5 of the 12 questions below (Madrigal Pharmaceuticals 5, Moderna 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionMDGLMRNANXTSLeader
Larger companyMarket capitalisation $12.83B $82.98B $473.36K MRNA
Cheaper on earningsLower P/E, profitable companies only -39.5x -26.3x 0.0x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months +149.0% -27.6% — MDGL
More profitableNet margin, trailing twelve months -25.3% -141.4% — MDGL
Better return on capitalReturn on invested capital — -43.3% — –
Less leveragedLower net debt / EBITDA 1.6x 1.5x 1.6x MRNA
Higher dividend yieldTrailing dividend yield — — — –
Better 1-year returnPrice return, last 12 months +1.0% +680.1% -97.8% MRNA
Better 5-year returnAnnualised price return, 5 years +41.0%/yr -9.8%/yr -86.1%/yr MDGL
Less volatileAnnualised volatility, 1 year 43.5% 130.8% 168.9% MDGL
Higher overall scoreMean of the five percentile scores vs peers 66/100 57/100 32/100 MDGL

Percentile Scorecard

MDGLMRNANXTS

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisMDGLMRNANXTS
Valuation 74 #163 of 625 69 #193 of 625 –
Growth 68 #194 of 602 18 #493 of 602 13 #523 of 602
Profitability 74 #144 of 551 57 #239 of 551 40 #329 of 551
Financial Health 41 #389 of 656 55 #298 of 656 43 #372 of 656
Shareholder Returns 75 #91 of 365 85 #57 of 365 –
Overall 66 57 32
  • MDGL ranked among 672 companies in Pharmaceuticals and Biotechnology
  • MRNA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • NXTS ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodMDGLMRNANXTSSPY
1 month -14.8%+4.6%-60.5% -0.2%
3 months -18.3%+272.6%-62.6% +3.9%
6 months -14.8%+341.2%-87.8% +8.2%
Year to date -24.4%+605.2%-95.1% +12.9%
1 year +1.0%+680.1%-97.8% +12.3%
3 years +265.7%+189.2%-99.9% +87.4%
3 years, per year +54.1%+42.5%-89.5% +23.3%
5 years +457.5%-40.2%-100.0% +67.9%
5 years, per year +41.0%-9.8%-86.1% +10.9%
10 years +2,491.7%—-100.0% +261.1%
10 years, per year +38.5%—-66.5% +13.7%

Risk

MeasureMDGLMRNANXTSSPY
Volatility, 1Y 43.5%130.8%168.9% 12.7%
Downside volatility, 1Y 41.4%79.5%153.3% 12.7%
Beta vs S&P 500, 1Y 0.302.152.33 1.00
Return / volatility, 1Y 0.025.20-0.58 0.97
Max drawdown, 5Y -61.4%-93.9%-100.0% -25.4%
From 52-week high -27.0%-15.4%-97.8% -1.2%
52-week high $602.83$245.81$26.04 $779.14
52-week low $412.35$22.36$0.53 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleMDGLMRNANXTS
P/E now vs peer median -39.5xmedian 17.2x -26.3xmedian 17.2x 0.0xmedian 17.2x
P/S now vs peer median 10.0xmedian 9.0x 37.2xmedian 9.0x —median 9.0x
EV/EBITDA now vs peer median -38.6xmedian 16.3x -25.5xmedian 16.3x 1.5xmedian 16.3x
P/FCF now vs peer median -62.2xmedian 18.7x -66.7xmedian 18.7x —median 18.7x
P/B now vs peer median 24.5xmedian 2.2x 12.3xmedian 2.2x 0.2xmedian 2.2x
PEG now vs peer median -2.67median 0.33 0.40median 0.33 0.00median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsMDGLMRNANXTS
Revenue $1.28B $2.23B –
Gross profit – $521.00M –
Operating income -$322.62M -$3.32B -$5.28M
Net income -$325.11M -$3.15B -$14.06M
Free cash flow -$206.29M -$1.24B –
R&D $490.14M $2.88B $532.00K
EPS (diluted) $-11.15 $-7.92 $-17.10
Cash & equivalents $292.73M $1.72B $7.62M
Total debt $340.79M $591.00M $3.22M
Shares (diluted) 29.15M 398.00M 816.14K
Enterprise value $9.09B $62.33B -$22.29M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricMDGLMRNANXTS
P/E -39.5x -26.3x 0.0x
P/FCF -62.2x -66.7x –
P/Operating cash flow -64.9x -77.3x –
P/S 10.0x 37.2x –
P/B 24.5x 12.3x 0.2x
P/Tangible book 24.8x 12.3x -0.2x
EV/EBITDA -38.6x -25.5x 1.5x
EV/EBIT -38.2x -23.6x 1.5x
EV/Revenue 9.6x 35.2x –
EV/FCF -59.8x -63.0x –
EV/Operating cash flow -62.4x -73.1x –
PEG (3Y EPS CAGR) -2.67 0.40 0.00

Growth

14 metrics
MetricMDGLMRNANXTS
Revenue growth (1Y) 149.0% -27.6% –
Revenue CAGR (3Y) – -40.6% –
Gross profit growth (1Y) – -67.8% –
Gross profit CAGR (3Y) – -56.0% –
Operating income growth (1Y) -4.1% -1.4% -7.7%
Operating income CAGR (3Y) 0.8% -103.9% 3.0%
Net income growth (1Y) -15.3% -8.5% -48.2%
Net income CAGR (3Y) 0.5% -66.4% -35.8%
EPS growth (1Y) 12.1% -5.8% -567.8%
EPS CAGR (3Y) 14.8% -65.1% -45.2%
Operating cash flow growth (1Y) 35.7% 60.2% –
Operating cash flow CAGR (3Y) 10.6% -68.1% –
Free cash flow growth (1Y) 33.1% 64.4% –
Free cash flow CAGR (3Y) 9.4% -18.2% –

Profitability

14 metrics
MetricMDGLMRNANXTS
Gross margin – 23.4% –
EBITDA margin -24.9% -138.2% –
Operating margin -25.1% -149.0% –
Pretax margin -24.8% -138.6% –
Net margin -25.3% -141.4% –
FCF margin -16.1% -55.8% –
Operating cash flow margin -15.4% -48.2% –
Return on equity -59.8% -44.5% -157.0%
Return on assets -25.8% -28.1% -71.9%
Return on invested capital – -43.3% –
Return on capital employed -37.4% -38.2% -31.5%
Asset turnover 1.0x 0.2x –
Cash conversion (OCF / net income) 0.6x 0.3x –
Stock comp / revenue 9.5% 20.7% –

Financial Health

11 metrics
MetricMDGLMRNANXTS
Debt / assets 27.4% 5.4% 2.3%
Debt / equity 0.7x 0.1x 0.2x
Net debt / EBITDA 1.6x 1.5x 1.6x
Debt / FCF -1.7x -0.5x –
Liabilities / assets 57.9% 38.3% 89.8%
Equity / assets 42.1% 61.7% 10.2%
Interest coverage -10.2x – –
Current ratio 3.2x 2.3x 3.7x
Quick ratio 2.8x 2.0x 3.2x
Cash ratio 2.2x 2.0x 3.2x
Altman Z-score 9.13 12.07 –

Shareholder Returns

7 metrics
MetricMDGLMRNANXTS
Dividend yield – – –
Net buyback yield -0.3% -0.1% –
Shareholder yield -0.3% -0.1% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusMDGLMRNANXTS
EPS, next fiscal year $-6.25FY2026 $-8.02FY2026 –
Revenue, next fiscal year $1.46BFY2026 $2.04BFY2026 –
Revenue growth, next FY +52.7%FY2026 +5.1%FY2026 –
Revenue growth, the year after +36.3% +26.8% –

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersMDGLMRNANXTS
Held by institutions 80.9% 80.2% –
Institutions holding 412 784 –
Change in shares held, QoQ -0.6% +3.4% –
Institutions buying 225 402 –
Institutions selling 128 238 –
Buyers to sellers 1.76 1.69 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

MDGLMRNANXTS
MDGL 1.00 0.13 0.03
MRNA 0.13 1.00 -0.05
NXTS 0.03 -0.05 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, MDGL, MRNA and NXTS?

Moderna (MRNA) is the largest by market capitalisation: Madrigal Pharmaceuticals (MDGL) $12.83B, Moderna (MRNA) $82.98B, Nexentis Technologies (NXTS) $473.36K.

Which company is growing faster?

Madrigal Pharmaceuticals (MDGL) grew revenue fastest over the trailing twelve months: Madrigal Pharmaceuticals (MDGL) +149.0%, Moderna (MRNA) -27.6%.

Which company is more profitable?

Madrigal Pharmaceuticals (MDGL) has the highest net margin (Madrigal Pharmaceuticals (MDGL) -25.3%, Moderna (MRNA) -141.4%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: Madrigal Pharmaceuticals (MDGL) +1.0%, Moderna (MRNA) +680.1%, Nexentis Technologies (NXTS) -97.8%. Over five years, Madrigal Pharmaceuticals (MDGL) compounded fastest (Madrigal Pharmaceuticals (MDGL) +41.0%/yr, Moderna (MRNA) -9.8%/yr, Nexentis Technologies (NXTS) -86.1%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Madrigal Pharmaceuticals (MDGL) has been the steadiest (Madrigal Pharmaceuticals (MDGL) 43.5%, Moderna (MRNA) 130.8%, Nexentis Technologies (NXTS) 168.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, MDGL, MRNA and NXTS?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Madrigal Pharmaceuticals (MDGL) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.