MDGL vs GILD Stock Comparison

Madrigal Pharmaceuticals and Gilead Sciences Prices as of Oct 26, 2026 Peers: Industry group
GILD Gilead Sciences, Inc.
$158.69 +5.1% 1M +31.2% 1Y
Market cap
$196.28B
P/E
–
Revenue (TTM)
$30.46B
Div. yield
–
Biotechnology Healthcare
4 wins

Head to Head

8 decided of 12

Gilead Sciences leads on 4 of the 12 questions below (Gilead Sciences 4, Madrigal Pharmaceuticals 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionMDGLGILDLeader
Larger companyMarket capitalisation $12.79B $196.28B GILD
Cheaper on earningsLower P/E, profitable companies only -39.4x -60.6x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — –
Faster revenue growthRevenue growth, trailing twelve months +149.0% +5.5% MDGL
More profitableNet margin, trailing twelve months -25.3% -10.6% GILD
Better return on capitalReturn on invested capital — -6.0% –
Less leveragedLower net debt / EBITDA 1.6x 87.7x MDGL
Higher dividend yieldTrailing dividend yield 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +3.9% +31.2% GILD
Better 5-year returnAnnualised price return, 5 years +42.6%/yr +18.9%/yr MDGL
Less volatileAnnualised volatility, 1 year 43.6% 27.0% GILD
Higher overall scoreMean of the five percentile scores vs peers 66/100 61/100 MDGL

Percentile Scorecard

MDGLGILD

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisMDGLGILD
Valuation 74 #161 of 626 90 #62 of 626
Growth 68 #194 of 604 31 #420 of 604
Profitability 74 #146 of 555 85 #85 of 555
Financial Health 41 #391 of 658 21 #518 of 658
Shareholder Returns 75 #92 of 368 77 #85 of 368
Overall 66 61
  • MDGL ranked among 673 companies in Pharmaceuticals and Biotechnology
  • GILD ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodMDGLGILDSPY
1 month -15.3%+5.1% -0.8%
3 months -20.6%+21.6% +3.5%
6 months -15.8%+24.2% +7.0%
Year to date -24.8%+29.3% +12.2%
1 year +3.9%+31.2% +13.0%
3 years +263.6%+107.1% +86.3%
3 years, per year +53.8%+27.5% +23.1%
5 years +489.7%+137.7% +68.6%
5 years, per year +42.6%+18.9% +11.0%
10 years +2,473.4%+110.5% +258.0%
10 years, per year +38.4%+7.7% +13.6%

Risk

MeasureMDGLGILDSPY
Volatility, 1Y 43.6%27.0% 12.7%
Downside volatility, 1Y 41.4%24.0% 12.7%
Beta vs S&P 500, 1Y 0.300.30 1.00
Return / volatility, 1Y 0.091.16 1.02
Max drawdown, 5Y -61.4%-29.4% -25.4%
From 52-week high -27.4%0.0% -1.8%
52-week high $602.83$158.69 $779.14
52-week low $412.35$117.88 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleMDGLGILD
P/E now vs peer median -39.2xmedian 17.1x -60.9xmedian 17.1x
P/S now vs peer median 9.9xmedian 8.8x 6.5xmedian 8.8x
EV/EBITDA now vs peer median -38.4xmedian 17.1x 836.5xmedian 17.1x
P/FCF now vs peer median -61.8xmedian 18.0x 15.2xmedian 18.0x
P/B now vs peer median 24.4xmedian 2.1x 16.6xmedian 2.1x
PEG now vs peer median -2.66median 0.31 1.62median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsMDGLGILD
Revenue $1.28B $30.46B
Gross profit – $24.24B
Operating income -$322.62M -$2.50B
Net income -$325.11M -$3.24B
Free cash flow -$206.29M $12.94B
R&D $490.14M $6.07B
EPS (diluted) $-11.15 $-2.61
Cash & equivalents $292.73M $3.18B
Total debt $340.79M $26.25B
Shares (diluted) 29.15M 1.24B
Enterprise value $9.05B $170.48B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricMDGLGILD
P/E -39.2x -60.9x
P/FCF -61.8x 15.2x
P/Operating cash flow -64.5x 14.5x
P/S 9.9x 6.5x
P/B 24.4x 16.6x
P/Tangible book 24.7x -89.4x
EV/EBITDA -38.4x 836.5x
EV/EBIT -38.0x -88.1x
EV/Revenue 9.5x 7.2x
EV/FCF -59.4x 17.0x
EV/Operating cash flow -62.0x 16.2x
PEG (3Y EPS CAGR) -2.66 1.62

Growth

14 metrics
MetricMDGLGILD
Revenue growth (1Y) 149.0% 5.5%
Revenue CAGR (3Y) – 3.6%
Gross profit growth (1Y) – 6.9%
Gross profit CAGR (3Y) – 3.7%
Operating income growth (1Y) -4.1% -131.0%
Operating income CAGR (3Y) 0.8% -31.9%
Net income growth (1Y) -15.3% -151.3%
Net income CAGR (3Y) 0.5% -37.3%
EPS growth (1Y) 12.1% -151.8%
EPS CAGR (3Y) 14.8% -37.5%
Operating cash flow growth (1Y) 35.7% 37.3%
Operating cash flow CAGR (3Y) 10.6% 12.5%
Free cash flow growth (1Y) 33.1% 38.1%
Free cash flow CAGR (3Y) 9.4% 13.2%

Profitability

14 metrics
MetricMDGLGILD
Gross margin – 79.6%
EBITDA margin -24.9% 0.9%
Operating margin -25.1% -8.2%
Pretax margin -24.8% -6.4%
Net margin -25.3% -10.6%
FCF margin -16.1% 42.5%
Operating cash flow margin -15.4% 44.5%
Return on equity -59.8% -18.4%
Return on assets -25.8% -6.1%
Return on invested capital – -6.0%
Return on capital employed -37.4% -6.0%
Asset turnover 1.0x 0.6x
Cash conversion (OCF / net income) 0.6x -4.2x
Stock comp / revenue 9.5% 3.0%

Financial Health

11 metrics
MetricMDGLGILD
Debt / assets 27.4% 53.2%
Debt / equity 0.7x 2.2x
Net debt / EBITDA 1.6x 87.7x
Debt / FCF -1.7x 2.0x
Liabilities / assets 57.9% 76.0%
Equity / assets 42.1% 24.0%
Interest coverage -10.2x -2.5x
Current ratio 3.2x 1.3x
Quick ratio 2.8x 0.7x
Cash ratio 2.2x 0.3x
Altman Z-score 9.07 3.73

Shareholder Returns

7 metrics
MetricMDGLGILD
Dividend yield – 2.0%
Net buyback yield -0.3% 0.6%
Shareholder yield -0.3% 2.6%
Payout ratio (earnings) – –
Payout ratio (FCF) – –
Dividend growth (1Y) – –
Dividend CAGR (3Y) – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusMDGLGILD
EPS, next fiscal year $-6.25FY2026 $-0.39FY2026
EPS growth, next FY – -104.8%FY2026
Revenue, next fiscal year $1.46BFY2026 $28.65BFY2026
Revenue growth, next FY +52.7%FY2026 -2.7%FY2026
Revenue growth, the year after +36.3% +18.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersMDGLGILD
Held by institutions 80.9% 89.6%
Institutions holding 412 2,290
Change in shares held, QoQ -0.6% +5.1%
Institutions buying 225 1,113
Institutions selling 128 850
Buyers to sellers 1.76 1.31

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

MDGLGILD
MDGL 1.00 0.19
GILD 0.19 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, MDGL and GILD?

Gilead Sciences (GILD) is the largest by market capitalisation: Madrigal Pharmaceuticals (MDGL) $12.79B, Gilead Sciences (GILD) $196.28B.

Which company is growing faster?

Madrigal Pharmaceuticals (MDGL) grew revenue fastest over the trailing twelve months: Madrigal Pharmaceuticals (MDGL) +149.0%, Gilead Sciences (GILD) +5.5%.

Which company is more profitable?

Gilead Sciences (GILD) has the highest net margin (Madrigal Pharmaceuticals (MDGL) -25.3%, Gilead Sciences (GILD) -10.6%).

Which stock has performed better?

Over the past year Gilead Sciences (GILD) returned the most: Madrigal Pharmaceuticals (MDGL) +3.9%, Gilead Sciences (GILD) +31.2%. Over five years, Madrigal Pharmaceuticals (MDGL) compounded fastest (Madrigal Pharmaceuticals (MDGL) +42.6%/yr, Gilead Sciences (GILD) +18.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Gilead Sciences (GILD) has been the steadiest (Madrigal Pharmaceuticals (MDGL) 43.6%, Gilead Sciences (GILD) 27.0%). Volatility measures how widely the price swings, not the risk of the business.

Do MDGL and GILD move together?

Their daily returns over the past year have a correlation of 0.19, a weak relationship. Holding both diversifies more than two closely linked stocks would.

Which is the better stock, MDGL and GILD?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Gilead Sciences (GILD) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.