LEGN vs PGEN vs SLBT Stock Comparison

Legend Biotech, Precigen and SL Science Holding Prices as of Nov 2, 2026 Peers: Industry group
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LEGN Legend Biotech Corp
$21.10 +13.6% 1M -34.9% 1Y
Market cap
$3.89B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
5 wins
PGEN Precigen, Inc.
$5.14 -39.8% 1M +24.2% 1Y
Market cap
$1.84B
P/E
–
Revenue (TTM)
$85.72M
Div. yield
–
Gene and Cell Therapy Healthcare
3 wins

Head to Head

8 decided of 12

Legend Biotech leads on 5 of the 12 questions below (Legend Biotech 5, Precigen 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionLEGNPGENSLBTLeader
Larger companyMarket capitalisation $3.89B $1.84B $2.77B LEGN
Cheaper on earningsLower P/E, profitable companies only -42.4x -5.4x — –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 30.2x — –
Faster revenue growthRevenue growth, trailing twelve months +59.5% +1,875.0% — PGEN
More profitableNet margin, trailing twelve months -7.2% -392.8% — LEGN
Better return on capitalReturn on invested capital -4.2% — — –
Less leveragedLower net debt / EBITDA -130.2x -1.6x — LEGN
Higher dividend yieldTrailing dividend yield — — 0.00% –
Better 1-year returnPrice return, last 12 months -34.9% +24.2% -87.8% PGEN
Better 5-year returnAnnualised price return, 5 years -16.4%/yr -1.3%/yr — PGEN
Less volatileAnnualised volatility, 1 year 72.5% 84.1% 176.0% LEGN
Higher overall scoreMean of the five percentile scores vs peers 74/100 54/100 — LEGN

Percentile Scorecard

LEGNPGENSLBT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisLEGNPGENSLBT
Valuation 89 #71 of 623 56 #275 of 623 11 #555 of 623
Growth 97 #20 of 601 48 #311 of 601 –
Profitability 80 #112 of 553 58 #232 of 553 –
Financial Health 60 #263 of 654 26 #485 of 654 58 #276 of 654
Shareholder Returns 44 #207 of 367 81 #69 of 367 –
Overall 74 54 –
  • LEGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • PGEN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • SLBT ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodLEGNPGENSLBTSPY
1 month +13.6%-39.8%-19.1% -2.3%
3 months +11.0%-22.2%-61.4% -0.7%
6 months -20.4%+24.2%-85.1% +4.8%
Year to date -2.9%+23.0%-88.0% +10.3%
1 year -34.9%+24.2%-87.8% +10.3%
3 years -68.0%+324.8%— +73.0%
3 years, per year -31.6%+62.0%— +20.1%
5 years -59.2%-6.5%— +61.9%
5 years, per year -16.4%-1.3%— +10.1%
10 years —-79.7%— +258.6%
10 years, per year —-14.8%— +13.6%

Risk

MeasureLEGNPGENSLBTSPY
Volatility, 1Y 72.5%84.1%176.0% 12.8%
Downside volatility, 1Y 62.7%81.1%170.0% 12.8%
Beta vs S&P 500, 1Y 0.481.440.18 1.00
Return / volatility, 1Y -0.480.29-0.50 0.80
Max drawdown, 5Y -78.2%-87.8%-91.0% -25.4%
From 52-week high -41.8%-40.0%-90.1% -3.5%
52-week high $36.28$8.56$12.81 $779.14
52-week low $16.65$3.10$1.15 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleLEGNPGENSLBT
P/E now vs peer median -42.4xmedian 17.4x -5.4xmedian 17.4x —median 17.4x
P/S now vs peer median 3.1xmedian 8.9x 21.5xmedian 8.9x —median 8.9x
EV/EBITDA now vs peer median 850.2xmedian 17.0x -55.3xmedian 17.0x —median 17.0x
P/FCF now vs peer median -60.2xmedian 21.4x -16.0xmedian 21.4x -1,475xmedian 21.4x
P/B now vs peer median 3.2xmedian 2.1x 42.2xmedian 2.1x 397.2xmedian 2.1x
PEG now vs peer median -0.90median 0.35 0.04median 0.35 —median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsLEGNPGENSLBT
Revenue $1.27B $85.72M –
Gross profit $727.10M $77.72M –
Operating income -$55.25M -$39.50M –
Net income -$80.39M -$157.71M –
Free cash flow -$64.60M -$115.22M –
R&D $396.15M $32.29M –
EPS (diluted) $-0.50 $-0.81 –
Cash & equivalents $672.90M $16.33M $8.31M
Total debt $156.40M $93.88M –
Shares (diluted) 184.32M 413.69M –
Enterprise value $1.39B $1.53B $2.76B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricLEGNPGENSLBT
P/E -42.4x -5.4x –
P/FCF -60.2x -16.0x -1,475x
P/Operating cash flow -43.5x -16.1x –
P/S 3.1x 21.5x –
P/B 3.2x 42.2x 397.2x
P/Tangible book 3.2x 44.8x 397.2x
EV/EBITDA 850.2x -55.3x –
EV/EBIT -61.0x -48.0x –
EV/Revenue 2.7x 22.1x –
EV/FCF -52.2x -16.5x –
EV/Operating cash flow -37.7x -16.6x –
PEG (3Y EPS CAGR) -0.90 0.04 –

Growth

14 metrics
MetricLEGNPGENSLBT
Revenue growth (1Y) 59.5% 1,875% –
Revenue CAGR (3Y) 97.6% 57.1% –
Gross profit growth (1Y) 42.4% 259,173% –
Gross profit CAGR (3Y) 147.5% 69.2% –
Operating income growth (1Y) 75.3% 62.1% –
Operating income CAGR (3Y) 49.1% 18.9% –
Net income growth (1Y) 75.3% -26.7% –
Net income CAGR (3Y) 46.7% -108.9% –
EPS growth (1Y) 72.0% -93.8% –
EPS CAGR (3Y) 47.0% -123.2% –
Operating cash flow growth (1Y) 67.5% -72.3% –
Operating cash flow CAGR (3Y) 37.1% -15.9% –
Free cash flow growth (1Y) 77.8% -65.1% –
Free cash flow CAGR (3Y) 44.5% -15.3% –

Profitability

14 metrics
MetricLEGNPGENSLBT
Gross margin 57.2% 90.7% –
EBITDA margin 0.3% -40.0% –
Operating margin -4.3% -46.1% –
Pretax margin -4.4% -184.0% –
Net margin -7.2% -392.8% –
FCF margin -5.1% -134.4% –
Operating cash flow margin -7.0% -133.2% –
Return on equity -8.3% -494.3% –
Return on assets -5.5% -102.1% –
Return on invested capital -4.2% – –
Return on capital employed -4.3% -31.6% –
Asset turnover 0.8x 0.6x –
Cash conversion (OCF / net income) 1.1x 0.7x –
Stock comp / revenue 5.2% 15.3% –

Financial Health

11 metrics
MetricLEGNPGENSLBT
Debt / assets 8.9% 55.1% –
Debt / equity 0.1x 2.2x –
Net debt / EBITDA -130.2x -1.6x –
Debt / FCF -2.4x -0.8x –
Liabilities / assets 29.8% 74.4% 21.8%
Equity / assets 70.2% 25.6% 78.2%
Interest coverage -4.8x -4.1x –
Current ratio 3.0x 4.6x 4.4x
Quick ratio 1.7x 3.8x 4.3x
Cash ratio 1.7x 1.3x 4.3x
Altman Z-score 6.65 -9.96 –

Shareholder Returns

7 metrics
MetricLEGNPGENSLBT
Dividend yield – – –
Net buyback yield -5.5% -0.1% –
Shareholder yield -5.5% -0.1% 0.0%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusLEGNPGENSLBT
Forward P/E – 30.2xFY2026 –
EPS, next fiscal year $-0.04FY2026 $0.17FY2026 –
EPS growth, the year after – +288.2% –
Revenue, next fiscal year $1.37BFY2026 $249.17MFY2026 –
Revenue growth, next FY +32.9%FY2026 +2,474.1%FY2026 –
Revenue growth, the year after +35.9% +82.3% –

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersLEGNPGENSLBT
Held by institutions 55.9% 39.2% –
Institutions holding 218 211 –
Change in shares held, QoQ +7.3% +4.9% –
Institutions buying 117 123 –
Institutions selling 78 46 –
Buyers to sellers 1.50 2.67 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

LEGNPGENSLBT
LEGN 1.00 0.07 -0.03
PGEN 0.07 1.00 -0.02
SLBT -0.03 -0.02 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, LEGN, PGEN and SLBT?

Legend Biotech (LEGN) is the largest by market capitalisation: Legend Biotech (LEGN) $3.89B, Precigen (PGEN) $1.84B, SL Science Holding (SLBT) $2.77B.

Which company is growing faster?

Precigen (PGEN) grew revenue fastest over the trailing twelve months: Legend Biotech (LEGN) +59.5%, Precigen (PGEN) +1,875.0%.

Which company is more profitable?

Legend Biotech (LEGN) has the highest net margin (Legend Biotech (LEGN) -7.2%, Precigen (PGEN) -392.8%).

Which stock has performed better?

Over the past year Precigen (PGEN) returned the most: Legend Biotech (LEGN) -34.9%, Precigen (PGEN) +24.2%, SL Science Holding (SLBT) -87.8%. Over five years, Precigen (PGEN) compounded fastest (Legend Biotech (LEGN) -16.4%/yr, Precigen (PGEN) -1.3%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Legend Biotech (LEGN) has been the steadiest (Legend Biotech (LEGN) 72.5%, Precigen (PGEN) 84.1%, SL Science Holding (SLBT) 176.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, LEGN, PGEN and SLBT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Legend Biotech (LEGN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.