LEGN vs IMMX vs NGNE Stock Comparison

Legend Biotech, Immix Biopharma and Neurogene Prices as of Nov 3, 2026 Peers: Industry group
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LEGN Legend Biotech Corp
$21.48 +15.7% 1M -33.1% 1Y
Market cap
$4.23B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
4 wins
IMMX Immix Biopharma, Inc.
$7.71 -20.4% 1M +111.8% 1Y
Market cap
$502.20M
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
1 win
NGNE Neurogene Inc.
$26.67 +4.0% 1M -14.1% 1Y
Market cap
$622.44M
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare

Head to Head

5 decided of 12

Legend Biotech leads on 4 of the 12 questions below (Legend Biotech 4, Immix Biopharma 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionLEGNIMMXNGNELeader
Larger companyMarket capitalisation $4.23B $502.20M $622.44M LEGN
Cheaper on earningsLower P/E, profitable companies only -46.2x -12.6x -5.6x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months +59.5% — — –
More profitableNet margin, trailing twelve months -7.2% — — –
Better return on capitalReturn on invested capital -4.2% — — –
Less leveragedLower net debt / EBITDA -130.2x — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -33.1% +111.8% -14.1% IMMX
Better 5-year returnAnnualised price return, 5 years -15.1%/yr — -29.1%/yr LEGN
Less volatileAnnualised volatility, 1 year 72.4% 83.0% 78.5% LEGN
Higher overall scoreMean of the five percentile scores vs peers 74/100 53/100 48/100 LEGN

Percentile Scorecard

LEGNIMMXNGNE

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisLEGNIMMXNGNE
Valuation 88 #75 of 634 74 #166 of 634 50 #320 of 634
Growth 97 #20 of 607 6 #573 of 607 22 #475 of 607
Profitability 80 #112 of 557 79 #117 of 557 54 #255 of 557
Financial Health 60 #262 of 654 97 #20 of 654 72 #184 of 654
Shareholder Returns 44 #227 of 401 9 #365 of 401 42 #233 of 401
Overall 74 53 48
  • LEGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • IMMX ranked among 671 companies in Pharmaceuticals and Biotechnology
  • NGNE ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodLEGNIMMXNGNESPY
1 month +15.7%-20.4%+4.0% -2.0%
3 months +12.3%-17.4%-22.5% -2.2%
6 months -24.7%-19.4%-7.8% +4.2%
Year to date -1.2%+47.4%+29.5% +10.6%
1 year -33.1%+111.8%-14.1% +10.4%
3 years -67.4%+116.0%+95.0% +73.6%
3 years, per year -31.2%+29.3%+24.9% +20.2%
5 years -55.9%—-82.1% +61.6%
5 years, per year -15.1%—-29.1% +10.1%
10 years ——-86.5% +261.3%
10 years, per year ——-18.2% +13.7%

Risk

MeasureLEGNIMMXNGNESPY
Volatility, 1Y 72.4%83.0%78.5% 12.8%
Downside volatility, 1Y 62.7%76.4%75.5% 12.8%
Beta vs S&P 500, 1Y 0.481.621.65 1.00
Return / volatility, 1Y -0.461.35-0.18 0.81
Max drawdown, 5Y -78.2%-88.9%-95.2% -25.4%
From 52-week high -40.8%-46.7%-37.7% -3.2%
52-week high $36.28$14.47$42.84 $779.14
52-week low $16.65$3.03$16.37 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleLEGNIMMXNGNE
P/E now vs peer median -43.2xmedian 18.4x -12.3xmedian 18.4x -5.4xmedian 18.4x
P/S now vs peer median 3.1xmedian 9.0x —median 9.0x —median 9.0x
EV/EBITDA now vs peer median 867.8xmedian 16.0x -7.7xmedian 16.0x -3.2xmedian 16.0x
P/FCF now vs peer median -61.3xmedian 21.8x -14.1xmedian 21.8x -6.9xmedian 21.8x
P/B now vs peer median 3.2xmedian 2.1x 2.4xmedian 2.1x 2.8xmedian 2.1x
PEG now vs peer median -0.92median 0.37 -2.00median 0.37 -0.16median 0.37

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsLEGNIMMXNGNE
Revenue $1.27B – –
Gross profit $727.10M – –
Operating income -$55.25M -$41.82M -$121.35M
Net income -$80.39M -$39.88M -$111.16M
Free cash flow -$64.60M -$39.09M -$87.75M
R&D $396.15M $21.62M $88.50M
EPS (diluted) $-0.50 $-0.63 $-4.93
Cash & equivalents $672.90M $225.49M $112.49M
Total debt $156.40M – –
Shares (diluted) 184.32M 63.77M 22.55M
Enterprise value $1.73B $270.10M -$380.56M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricLEGNIMMXNGNE
P/E -43.2x -12.3x -5.4x
P/FCF -61.3x -14.1x -6.9x
P/Operating cash flow -44.3x -14.3x -6.9x
P/S 3.1x – –
P/B 3.2x 2.4x 2.8x
P/Tangible book 3.2x 2.4x 2.8x
EV/EBITDA 867.8x -7.7x -3.2x
EV/EBIT -62.3x -7.6x -3.1x
EV/Revenue 2.7x – –
EV/FCF -53.3x -8.2x -4.3x
EV/Operating cash flow -38.5x -8.3x -4.3x
PEG (3Y EPS CAGR) -0.92 -2.00 -0.16

Growth

14 metrics
MetricLEGNIMMXNGNE
Revenue growth (1Y) 59.5% – –
Revenue CAGR (3Y) 97.6% – –
Gross profit growth (1Y) 42.4% – –
Gross profit CAGR (3Y) 147.5% – –
Operating income growth (1Y) 75.3% -75.8% -26.8%
Operating income CAGR (3Y) 49.1% -53.5% -33.6%
Net income growth (1Y) 75.3% -72.4% -31.7%
Net income CAGR (3Y) 46.7% -51.7% -32.0%
EPS growth (1Y) 72.0% 18.9% -23.0%
EPS CAGR (3Y) 47.0% 6.2% 34.1%
Operating cash flow growth (1Y) 67.5% -207.8% -18.5%
Operating cash flow CAGR (3Y) 37.1% -51.9% -19.9%
Free cash flow growth (1Y) 77.8% -190.0% -17.8%
Free cash flow CAGR (3Y) 44.5% -52.7% -19.1%

Profitability

14 metrics
MetricLEGNIMMXNGNE
Gross margin 57.2% – –
EBITDA margin 0.3% – –
Operating margin -4.3% – –
Pretax margin -4.4% – –
Net margin -7.2% – –
FCF margin -5.1% – –
Operating cash flow margin -7.0% – –
Return on equity -8.3% -25.5% -49.1%
Return on assets -5.5% -23.8% -44.0%
Return on invested capital -4.2% – –
Return on capital employed -4.3% -26.4% -52.2%
Asset turnover 0.8x – –
Cash conversion (OCF / net income) 1.1x 1.0x 0.8x
Stock comp / revenue 5.2% – –

Financial Health

11 metrics
MetricLEGNIMMXNGNE
Debt / assets 8.9% – –
Debt / equity 0.1x – –
Net debt / EBITDA -130.2x – –
Debt / FCF -2.4x – –
Liabilities / assets 29.8% 4.3% 11.1%
Equity / assets 70.2% 95.7% 88.9%
Interest coverage -4.8x – -60,673x
Current ratio 3.0x 25.1x 10.6x
Quick ratio 1.7x 25.0x 10.5x
Cash ratio 1.7x 25.0x 10.5x
Altman Z-score 6.73 – –

Shareholder Returns

7 metrics
MetricLEGNIMMXNGNE
Dividend yield – – –
Net buyback yield -5.4% -45.1% -6.1%
Shareholder yield -5.4% -45.1% -6.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusLEGNIMMXNGNE
EPS, next fiscal year $-0.04FY2026 $-0.70FY2026 $-5.76FY2026
Revenue, next fiscal year $1.37BFY2026 $0.00FY2026 $0.00FY2026
Revenue growth, next FY +32.9%FY2026 – –
Revenue growth, the year after +35.9% – –

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersLEGNIMMXNGNE
Held by institutions 55.9% 78.6% 76.8%
Institutions holding 218 110 113
Change in shares held, QoQ +7.3% +107.6% +2.0%
Institutions buying 117 81 61
Institutions selling 78 13 31
Buyers to sellers 1.50 6.23 1.97

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

LEGNIMMXNGNE
LEGN 1.00 0.05 0.18
IMMX 0.05 1.00 0.26
NGNE 0.18 0.26 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, LEGN, IMMX and NGNE?

Legend Biotech (LEGN) is the largest by market capitalisation: Legend Biotech (LEGN) $4.23B, Immix Biopharma (IMMX) $502.20M, Neurogene (NGNE) $622.44M.

Which stock has performed better?

Over the past year Immix Biopharma (IMMX) returned the most: Legend Biotech (LEGN) -33.1%, Immix Biopharma (IMMX) +111.8%, Neurogene (NGNE) -14.1%. Over five years, Legend Biotech (LEGN) compounded fastest (Legend Biotech (LEGN) -15.1%/yr, Neurogene (NGNE) -29.1%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Legend Biotech (LEGN) has been the steadiest (Legend Biotech (LEGN) 72.4%, Immix Biopharma (IMMX) 83.0%, Neurogene (NGNE) 78.5%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, LEGN, IMMX and NGNE?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Legend Biotech (LEGN) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.