ISRG vs RMTI vs SKYA Stock Comparison

Intuitive Surgical, Rockwell Medical and SkyAI Prices as of Oct 28, 2026 Peers: Industry group
ISRG Intuitive Surgical Inc
$444.18 +7.1% 1M -18.6% 1Y
Market cap
$156.90B
P/E
53.1x
Revenue (TTM)
$11.58B
Div. yield
–
Medical Devices Healthcare
4 wins
RMTI Rockwell Medical, Inc.
$7.31 -15.3% 1M +552.7% 1Y
Market cap
$28.30M
P/E
–
Revenue (TTM)
$69.39M
Div. yield
–
Medical Supplies Healthcare
2 wins
SKYA SkyAI, Inc.
$2.95 +66.7% 1M -42.7% 1Y
Market cap
$211.23M
P/E
–
Revenue (TTM)
$194.22K
Div. yield
–
Medical Supplies Healthcare
2 wins

Head to Head

8 decided of 12

Intuitive Surgical leads on 4 of the 12 questions below (Intuitive Surgical 4, SkyAI 2, Rockwell Medical 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionISRGRMTISKYALeader
Larger companyMarket capitalisation $156.90B $28.30M $211.23M ISRG
Cheaper on earningsLower P/E, profitable companies only 53.1x -5.6x -0.7x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 38.7x — 0.0x SKYA
Faster revenue growthRevenue growth, trailing twelve months +20.5% -21.1% +108.9% SKYA
More profitableNet margin, trailing twelve months 25.5% -7.3% -158,431.4% ISRG
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — 7.8x — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -18.6% +552.7% -42.7% RMTI
Better 5-year returnAnnualised price return, 5 years +4.2%/yr +4.2%/yr — RMTI
Less volatileAnnualised volatility, 1 year 34.6% 401.8% 105.9% ISRG
Higher overall scoreMean of the five percentile scores vs peers 80/100 57/100 26/100 ISRG

Percentile Scorecard

ISRGRMTISKYA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisISRGRMTISKYA
Valuation 53 #107 of 227 90 #24 of 227 2 #222 of 227
Growth 80 #44 of 219 26 #162 of 219 7 #204 of 219
Profitability 98 #6 of 205 57 #89 of 205 1 #203 of 205
Financial Health 78 #54 of 237 55 #108 of 237 95 #14 of 237
Shareholder Returns 91 #13 of 135 – –
Overall 80 57 26
  • ISRG ranked among 247 companies in Medical Devices and Diagnostics
  • RMTI ranked among 247 companies in Medical Devices and Diagnostics
  • SKYA ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodISRGRMTISKYASPY
1 month +7.1%-15.3%+66.7% +0.9%
3 months +25.8%+6.3%+115.3% +5.9%
6 months -2.1%+712.2%+68.6% +8.5%
Year to date -21.6%+780.7%+45.3% +13.3%
1 year -18.6%+552.7%-42.7% +12.4%
3 years +71.5%+337.7%-99.9% +88.1%
3 years, per year +19.7%+63.6%-90.0% +23.5%
5 years +23.0%+23.1%— +68.2%
5 years, per year +4.2%+4.2%— +11.0%
10 years +499.8%-88.3%— +263.4%
10 years, per year +19.6%-19.3%— +13.8%

Risk

MeasureISRGRMTISKYASPY
Volatility, 1Y 34.6%401.8%105.9% 12.7%
Downside volatility, 1Y 37.4%353.0%104.7% 12.7%
Beta vs S&P 500, 1Y 0.891.662.60 1.00
Return / volatility, 1Y -0.541.38-0.40 0.98
Max drawdown, 5Y -49.9%-91.1%-100.0% -25.4%
From 52-week high -25.1%-17.4%-42.7% -0.9%
52-week high $592.85$8.85$5.15 $779.14
52-week low $332.02$0.55$0.95 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleISRGRMTISKYA
P/E now vs peer median 52.4xmedian 28.8x -5.7xmedian 28.8x -0.7xmedian 28.8x
P/S now vs peer median 13.3xmedian 3.0x 0.4xmedian 3.0x 1,095xmedian 3.0x
EV/EBITDA now vs peer median 36.6xmedian 17.4x -6.6xmedian 17.4x —median 17.4x
P/FCF now vs peer median 42.8xmedian 25.7x 19.4xmedian 25.7x —median 25.7x
P/B now vs peer median 9.6xmedian 2.4x 0.8xmedian 2.4x 1.4xmedian 2.4x
PEG now vs peer median 2.04median 1.03 -0.14median 1.03 0.01median 1.03

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsISRGRMTISKYA
Revenue $11.58B $69.39M $194.22K
Gross profit $7.78B $12.29M $321.93K
Operating income $3.28B -$4.52M -$289.52M
Net income $2.97B -$5.08M -$307.71M
Free cash flow $3.60B $1.50M –
R&D $1.49B $40.00K $399.91K
EPS (diluted) $8.41 $-1.28 $-4.27
Cash & equivalents $2.98B $10.52M $12.07M
Total debt – $9.00M –
Shares (diluted) 351.60M 3.96M 72.09M
Enterprise value $137.19B -$69.09M $169.94M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricISRGRMTISKYA
P/E 52.4x -5.7x -0.7x
P/FCF 42.8x 19.4x –
P/Operating cash flow 37.6x 10.2x –
P/S 13.3x 0.4x 1,095x
P/B 9.6x 0.8x 1.4x
P/Tangible book 10.3x 1.1x 16.4x
EV/EBITDA 36.6x -6.6x –
EV/EBIT 45.6x -2.9x -0.7x
EV/Revenue 12.9x 0.2x 1,033x
EV/FCF 41.7x 8.8x –
EV/Operating cash flow 36.7x 4.6x –
PEG (3Y EPS CAGR) 2.04 -0.14 0.01

Growth

14 metrics
MetricISRGRMTISKYA
Revenue growth (1Y) 20.5% -21.1% 108.9%
Revenue CAGR (3Y) 19.1% -2.9% 23.8%
Gross profit growth (1Y) 21.9% -20.3% –
Gross profit CAGR (3Y) 19.5% 22.1% –
Operating income growth (1Y) 16.6% -250.1% -5,525%
Operating income CAGR (3Y) 24.8% 23.4% -212.8%
Net income growth (1Y) 7.5% -142.2% -42,440%
Net income CAGR (3Y) 24.4% 24.1% -238.0%
EPS growth (1Y) 10.8% -109.9% -487.2%
EPS CAGR (3Y) 25.7% 41.1% -84.2%
Operating cash flow growth (1Y) 38.1% -18.3% –
Operating cash flow CAGR (3Y) 26.4% 34.2% –
Free cash flow growth (1Y) 58.4% -44.2% –
Free cash flow CAGR (3Y) 42.0% 30.2% –

Profitability

14 metrics
MetricISRGRMTISKYA
Gross margin 67.2% 17.7% 165.8%
EBITDA margin 35.3% -2.9% –
Operating margin 28.4% -6.5% -149,065%
Pretax margin 31.3% -7.9% -151,352%
Net margin 25.5% -7.3% -158,431%
FCF margin 31.1% 2.2% –
Operating cash flow margin 35.3% 4.1% –
Return on equity 17.3% -15.5% -140.2%
Return on assets 14.8% -9.6% -137.6%
Return on invested capital – – –
Return on capital employed 18.7% -9.9% -136.7%
Asset turnover 0.6x 1.2x 0.0x
Cash conversion (OCF / net income) 1.4x -0.6x –
Stock comp / revenue 7.2% 2.7% 48,037%

Financial Health

11 metrics
MetricISRGRMTISKYA
Debt / assets – 15.9% –
Debt / equity – 0.3x –
Net debt / EBITDA – 7.8x –
Debt / FCF – 6.0x –
Liabilities / assets 16.7% 37.9% 1.9%
Equity / assets 83.3% 62.1% 98.1%
Interest coverage – -4.0x –
Current ratio 3.3x 3.3x 5.3x
Quick ratio 2.3x 3.0x 4.4x
Cash ratio 1.6x 2.2x 4.2x
Altman Z-score 30.44 -7.74 31.97

Shareholder Returns

7 metrics
MetricISRGRMTISKYA
Dividend yield – – –
Net buyback yield 2.8% – –
Shareholder yield 2.8% – –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusISRGRMTISKYA
Forward P/E 38.7xFY2026 – 0.0xFY2026
EPS, next fiscal year $11.47FY2026 $-0.97FY2026 $2,362.06FY2026
EPS growth, next FY +28.4%FY2026 – –
EPS growth, the year after +4.5% – –
Revenue, next fiscal year $11.60BFY2026 $77.07MFY2026 $70.01MFY2026
Revenue growth, next FY +15.3%FY2026 +11.3%FY2026 +34,200.1%FY2026
Revenue growth, the year after +11.3% +7.5% +17.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersISRGRMTISKYA
Held by institutions 86.2% 8.6% –
Institutions holding 2,236 33 –
Change in shares held, QoQ +4.6% -14.2% –
Institutions buying 1,071 13 –
Institutions selling 877 9 –
Buyers to sellers 1.22 1.44 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ISRGRMTISKYA
ISRG 1.00 0.07 0.15
RMTI 0.07 1.00 0.04
SKYA 0.15 0.04 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ISRG, RMTI and SKYA?

Intuitive Surgical (ISRG) is the largest by market capitalisation: Intuitive Surgical (ISRG) $156.90B, Rockwell Medical (RMTI) $28.30M, SkyAI (SKYA) $211.23M.

Which company is growing faster?

SkyAI (SKYA) grew revenue fastest over the trailing twelve months: Intuitive Surgical (ISRG) +20.5%, Rockwell Medical (RMTI) -21.1%, SkyAI (SKYA) +108.9%.

Which company is more profitable?

Intuitive Surgical (ISRG) has the highest net margin (Intuitive Surgical (ISRG) 25.5%, Rockwell Medical (RMTI) -7.3%, SkyAI (SKYA) -158,431.4%).

Which stock has performed better?

Over the past year Rockwell Medical (RMTI) returned the most: Intuitive Surgical (ISRG) -18.6%, Rockwell Medical (RMTI) +552.7%, SkyAI (SKYA) -42.7%. Over five years, Rockwell Medical (RMTI) compounded fastest (Intuitive Surgical (ISRG) +4.2%/yr, Rockwell Medical (RMTI) +4.2%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Intuitive Surgical (ISRG) has been the steadiest (Intuitive Surgical (ISRG) 34.6%, Rockwell Medical (RMTI) 401.8%, SkyAI (SKYA) 105.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ISRG, RMTI and SKYA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Intuitive Surgical (ISRG) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.