ISRG vs PEN vs ABT Stock Comparison

Intuitive Surgical, Penumbra and Abbott Laboratories Prices as of Oct 27, 2026 Peers: Industry group
ISRG Intuitive Surgical Inc
$445.88 +10.0% 1M -19.1% 1Y
Market cap
$155.46B
P/E
52.6x
Revenue (TTM)
$11.58B
Div. yield
–
Medical Devices Healthcare
4 wins
PEN Penumbra Inc
$324.07 +1.6% 1M +30.7% 1Y
Market cap
$12.55B
P/E
78.2x
Revenue (TTM)
$1.50B
Div. yield
–
Medical Devices Healthcare
2 wins
ABT Abbott Laboratories
$103.13 +1.8% 1M -18.9% 1Y
Market cap
$179.35B
P/E
38.2x
Revenue (TTM)
$48.23B
Div. yield
–
Medical Devices Healthcare
3 wins

Head to Head

9 decided of 12

Intuitive Surgical leads on 4 of the 12 questions below (Intuitive Surgical 4, Abbott Laboratories 3, Penumbra 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionISRGPENABTLeader
Larger companyMarket capitalisation $155.46B $12.55B $179.35B ABT
Cheaper on earningsLower P/E, profitable companies only 52.6x 78.2x 38.2x ABT
Cheaper on forward earningsLower price / next fiscal year consensus EPS 38.9x 72.3x 18.1x ABT
Faster revenue growthRevenue growth, trailing twelve months +20.5% +17.6% +10.0% ISRG
More profitableNet margin, trailing twelve months 25.5% 10.7% — ISRG
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -19.1% +30.7% -18.9% PEN
Better 5-year returnAnnualised price return, 5 years +4.6%/yr +3.1%/yr -4.2%/yr ISRG
Less volatileAnnualised volatility, 1 year 34.6% 26.4% 27.4% PEN
Higher overall scoreMean of the five percentile scores vs peers 80/100 74/100 60/100 ISRG

Percentile Scorecard

ISRGPENABT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisISRGPENABT
Valuation 54 #106 of 227 55 #103 of 227 74 #60 of 227
Growth 80 #45 of 219 93 #16 of 219 17 #181 of 219
Profitability 98 #6 of 206 86 #30 of 206 –
Financial Health 78 #53 of 238 85 #36 of 238 –
Shareholder Returns 92 #12 of 134 50 #68 of 134 90 #15 of 134
Overall 80 74 60
  • ISRG ranked among 247 companies in Medical Devices and Diagnostics
  • PEN ranked among 247 companies in Medical Devices and Diagnostics
  • ABT ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodISRGPENABTSPY
1 month +10.0%+1.6%+1.8% -0.2%
3 months +23.2%+1.3%-3.9% +3.9%
6 months -4.4%-0.6%+9.9% +8.2%
Year to date -21.3%+4.2%-17.7% +12.9%
1 year -19.1%+30.7%-18.9% +12.3%
3 years +72.2%+68.1%+11.1% +87.4%
3 years, per year +19.9%+18.9%+3.6% +23.3%
5 years +25.4%+16.6%-19.2% +67.9%
5 years, per year +4.6%+3.1%-4.2% +10.9%
10 years +505.1%+401.7%+156.0% +261.1%
10 years, per year +19.7%+17.5%+9.9% +13.7%

Risk

MeasureISRGPENABTSPY
Volatility, 1Y 34.6%26.4%27.4% 12.7%
Downside volatility, 1Y 37.4%17.7%27.5% 12.7%
Beta vs S&P 500, 1Y 0.890.06-0.01 1.00
Return / volatility, 1Y -0.551.16-0.69 0.97
Max drawdown, 5Y -49.9%-59.7%-41.6% -25.4%
From 52-week high -24.8%-9.8%-21.0% -1.2%
52-week high $592.85$359.40$130.59 $779.14
52-week low $332.02$225.54$82.56 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleISRGPENABT
P/E now vs peer median 52.6xmedian 29.6x 79.4xmedian 29.6x 38.2xmedian 29.6x
P/S now vs peer median 13.3xmedian 2.9x 8.5xmedian 2.9x 3.7xmedian 2.9x
EV/EBITDA now vs peer median 36.8xmedian 17.4x 59.2xmedian 17.4x —median 17.4x
P/FCF now vs peer median 43.0xmedian 22.3x 59.1xmedian 22.3x 22.3xmedian 22.3x
P/B now vs peer median 9.6xmedian 2.3x 8.3xmedian 2.3x —median 2.3x
PEG now vs peer median 2.05median 1.04 1.04median 1.04 -12.85median 1.04

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsISRGPENABT
Revenue $11.58B $1.50B $48.23B
Gross profit $7.78B $1.02B –
Operating income $3.28B $187.34M $6.65B
Net income $2.97B $160.59M –
Free cash flow $3.60B $215.91M –
R&D $1.49B $92.25M $3.31B
EPS (diluted) $8.41 $4.06 $2.70
Cash & equivalents $2.98B $205.27M –
Shares (diluted) 351.60M 39.57M 1.74B
Enterprise value $135.74B $10.26B $179.35B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricISRGPENABT
P/E 52.6x 79.4x 38.2x
P/FCF 43.0x 59.1x 22.3x
P/Operating cash flow 37.8x 45.9x –
P/S 13.3x 8.5x 3.7x
P/B 9.6x 8.3x –
P/Tangible book 10.4x 8.4x –
EV/EBITDA 36.8x 59.2x –
EV/EBIT 45.8x 64.6x –
EV/Revenue 13.0x 8.0x 3.7x
EV/FCF 41.8x 56.1x –
EV/Operating cash flow 36.8x 43.6x –
PEG (3Y EPS CAGR) 2.05 1.04 -12.85

Growth

14 metrics
MetricISRGPENABT
Revenue growth (1Y) 20.5% 17.6% 10.0%
Revenue CAGR (3Y) 19.1% 17.1% 6.5%
Gross profit growth (1Y) 21.9% 20.0% –
Gross profit CAGR (3Y) 19.5% 19.9% –
Operating income growth (1Y) 16.6% 17.6% -13.8%
Operating income CAGR (3Y) 24.8% 73.0% 3.5%
Net income growth (1Y) 7.5% 8.7% –
Net income CAGR (3Y) 24.4% 76.7% –
EPS growth (1Y) 10.8% 7.8% -66.2%
EPS CAGR (3Y) 25.7% 76.1% -3.0%
Operating cash flow growth (1Y) 38.1% 37.9% –
Operating cash flow CAGR (3Y) 26.4% 146.0% –
Free cash flow growth (1Y) 58.4% 33.6% –
Free cash flow CAGR (3Y) 42.0% 650.9% –

Profitability

14 metrics
MetricISRGPENABT
Gross margin 67.2% 67.8% –
EBITDA margin 35.3% 13.6% –
Operating margin 28.4% 12.4% –
Pretax margin 31.3% 13.5% –
Net margin 25.5% 10.7% –
FCF margin 31.1% 14.3% –
Operating cash flow margin 35.3% 18.5% –
Return on equity 17.3% 10.7% –
Return on assets 14.8% 8.3% –
Return on invested capital – – –
Return on capital employed 18.7% 11.0% –
Asset turnover 0.6x 0.8x –
Cash conversion (OCF / net income) 1.4x 1.7x –
Stock comp / revenue 7.2% 4.0% –

Financial Health

11 metrics
MetricISRGPENABT
Debt / assets – – –
Debt / equity – – –
Net debt / EBITDA – – –
Debt / FCF – – –
Liabilities / assets 16.7% 22.5% –
Equity / assets 83.3% 77.5% –
Interest coverage – – –
Current ratio 3.3x 5.7x –
Quick ratio 2.3x 3.6x –
Cash ratio 1.6x 2.8x –
Altman Z-score 30.55 19.22 –

Shareholder Returns

7 metrics
MetricISRGPENABT
Dividend yield – – 2.4%
Net buyback yield 2.8% -0.2% –
Shareholder yield 2.8% -0.2% 2.4%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusISRGPENABT
Forward P/E 38.9xFY2026 72.3xFY2026 18.1xFY2026
EPS, next fiscal year $11.47FY2026 $4.48FY2026 $5.69FY2026
EPS growth, next FY +28.4%FY2026 +16.7%FY2026 +10.5%FY2026
EPS growth, the year after +4.5% +42.6% +10.4%
Revenue, next fiscal year $11.60BFY2026 $1.63BFY2026 $53.00BFY2026
Revenue growth, next FY +15.3%FY2026 +16.3%FY2026 +19.5%FY2026
Revenue growth, the year after +11.3% +7.5% -2.2%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersISRGPENABT
Held by institutions 86.2% 86.6% 79.2%
Institutions holding 2,235 451 2,979
Change in shares held, QoQ +4.6% +0.9% +0.3%
Institutions buying 1,070 195 1,259
Institutions selling 877 182 1,377
Buyers to sellers 1.22 1.07 0.91

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ISRGPENABT
ISRG 1.00 0.12 0.32
PEN 0.12 1.00 0.15
ABT 0.32 0.15 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ISRG, PEN and ABT?

Abbott Laboratories (ABT) is the largest by market capitalisation: Intuitive Surgical (ISRG) $155.46B, Penumbra (PEN) $12.55B, Abbott Laboratories (ABT) $179.35B.

Which stock is cheaper, ISRG, PEN and ABT?

Abbott Laboratories (ABT) trades on the lowest price-to-earnings ratio (Intuitive Surgical (ISRG) 52.6x, Penumbra (PEN) 78.2x, Abbott Laboratories (ABT) 38.2x). On next year's consensus earnings, Abbott Laboratories (ABT) is cheapest (Intuitive Surgical (ISRG) 38.9x, Penumbra (PEN) 72.3x, Abbott Laboratories (ABT) 18.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Intuitive Surgical (ISRG) grew revenue fastest over the trailing twelve months: Intuitive Surgical (ISRG) +20.5%, Penumbra (PEN) +17.6%, Abbott Laboratories (ABT) +10.0%.

Which company is more profitable?

Intuitive Surgical (ISRG) has the highest net margin (Intuitive Surgical (ISRG) 25.5%, Penumbra (PEN) 10.7%).

Which stock has performed better?

Over the past year Penumbra (PEN) returned the most: Intuitive Surgical (ISRG) -19.1%, Penumbra (PEN) +30.7%, Abbott Laboratories (ABT) -18.9%. Over five years, Intuitive Surgical (ISRG) compounded fastest (Intuitive Surgical (ISRG) +4.6%/yr, Penumbra (PEN) +3.1%/yr, Abbott Laboratories (ABT) -4.2%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Penumbra (PEN) has been the steadiest (Intuitive Surgical (ISRG) 34.6%, Penumbra (PEN) 26.4%, Abbott Laboratories (ABT) 27.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ISRG, PEN and ABT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Intuitive Surgical (ISRG) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.