ISRG vs JNJ vs LLY Stock Comparison

Intuitive Surgical, Johnson & Johnson and Eli Lilly Prices as of Oct 29, 2026 Peers: Industry group
ISRG Intuitive Surgical Inc
$448.76 +8.9% 1M -16.5% 1Y
Market cap
$150.86B
P/E
51.0x
Revenue (TTM)
$11.58B
Div. yield
–
Medical Devices Healthcare
1 win
JNJ Johnson & Johnson
$275.17 +2.8% 1M +47.5% 1Y
Market cap
$660.04B
P/E
41.0x
Revenue (TTM)
$99.34B
Div. yield
0.02%
Pharmaceuticals Healthcare
4 wins
LLY ELI LILLY & Co
$1,373.00 +15.8% 1M +68.8% 1Y
Market cap
$1.26T
P/E
45.8x
Revenue (TTM)
$86.46B
Div. yield
–
Pharmaceuticals Healthcare
6 wins

Head to Head

11 decided of 12

Eli Lilly leads on 6 of the 12 questions below (Eli Lilly 6, Johnson & Johnson 4, Intuitive Surgical 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionISRGJNJLLYLeader
Larger companyMarket capitalisation $150.86B $660.04B $1.26T LLY
Cheaper on earningsLower P/E, profitable companies only 51.0x 41.0x 45.8x JNJ
Cheaper on forward earningsLower price / next fiscal year consensus EPS 39.1x 25.7x 42.4x JNJ
Faster revenue growthRevenue growth, trailing twelve months +20.5% +7.8% +45.5% LLY
More profitableNet margin, trailing twelve months 25.5% 16.2% 31.9% LLY
Better return on capitalReturn on invested capital — 17.6% 38.2% LLY
Less leveragedLower net debt / EBITDA — 0.8x 1.0x JNJ
Higher dividend yieldTrailing dividend yield 0.00% 0.02% 0.00% –
Better 1-year returnPrice return, last 12 months -16.5% +47.5% +68.8% LLY
Better 5-year returnAnnualised price return, 5 years +4.4%/yr +11.1%/yr +40.1%/yr LLY
Less volatileAnnualised volatility, 1 year 34.6% 20.9% 35.3% JNJ
Higher overall scoreMean of the five percentile scores vs peers 80/100 68/100 72/100 ISRG

Percentile Scorecard

ISRGJNJLLY

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisISRGJNJLLY
Valuation 53 #107 of 227 86 #88 of 624 76 #151 of 624
Growth 80 #44 of 218 42 #351 of 601 97 #19 of 601
Profitability 98 #6 of 202 93 #37 of 541 98 #12 of 541
Financial Health 77 #54 of 233 41 #380 of 647 28 #464 of 647
Shareholder Returns 91 #13 of 130 76 #88 of 359 63 #135 of 359
Overall 80 68 72
  • ISRG ranked among 247 companies in Medical Devices and Diagnostics
  • JNJ ranked among 671 companies in Pharmaceuticals and Biotechnology
  • LLY ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodISRGJNJLLYSPY
1 month +8.9%+2.8%+15.8% +0.7%
3 months +27.1%+7.5%+18.8% +3.7%
6 months -1.9%+19.7%+46.9% +7.1%
Year to date -20.8%+33.0%+27.8% +12.8%
1 year -16.5%+47.5%+68.8% +11.9%
3 years +73.6%+87.2%+142.7% +85.2%
3 years, per year +20.2%+23.3%+34.4% +22.8%
5 years +24.3%+68.9%+438.9% +67.6%
5 years, per year +4.4%+11.1%+40.1% +10.9%
10 years +505.9%+138.6%+1,742.2% +262.0%
10 years, per year +19.7%+9.1%+33.8% +13.7%

Risk

MeasureISRGJNJLLYSPY
Volatility, 1Y 34.6%20.9%35.3% 12.7%
Downside volatility, 1Y 37.5%20.1%30.1% 12.6%
Beta vs S&P 500, 1Y 0.89-0.220.22 1.00
Return / volatility, 1Y -0.482.281.95 0.94
Max drawdown, 5Y -49.9%-23.6%-34.8% -25.4%
From 52-week high -24.3%-1.2%0.0% -1.2%
52-week high $592.85$278.47$1,373.00 $779.14
52-week low $332.02$186.00$813.53 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleISRGJNJLLY
P/E now vs peer median 53.0xmedian 28.7x 41.2xmedian 17.8x 44.4xmedian 17.8x
P/S now vs peer median 13.4xmedian 3.0x 6.7xmedian 9.1x 14.9xmedian 9.1x
EV/EBITDA now vs peer median 37.0xmedian 17.8x 20.7xmedian 15.0x 29.6xmedian 15.0x
P/FCF now vs peer median 43.2xmedian 26.4x 32.2xmedian 21.7x 65.7xmedian 21.7x
P/B now vs peer median 9.7xmedian 2.4x 8.1xmedian 2.2x 32.1xmedian 2.2x
PEG now vs peer median 2.06median 0.99 -1.92median 0.35 0.57median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsISRGJNJLLY
Revenue $11.58B $99.34B $86.46B
Gross profit $7.78B $67.11B $72.31B
Operating income $3.28B $25.19B $42.95B
Net income $2.97B $16.10B $27.58B
Free cash flow $3.60B $20.59B $19.66B
R&D $1.49B $16.08B $15.38B
EPS (diluted) $8.41 $6.57 $30.87
Cash & equivalents $2.98B $16.91B $4.89B
Total debt – $44.65B $49.50B
Shares (diluted) 351.60M 2.45B 893.40M
Enterprise value $131.14B $579.90B $1.24T

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricISRGJNJLLY
P/E 53.0x 41.2x 44.4x
P/FCF 43.2x 32.2x 65.7x
P/Operating cash flow 38.0x 25.3x 42.1x
P/S 13.4x 6.7x 14.9x
P/B 9.7x 8.1x 32.1x
P/Tangible book 10.4x 19.0x 58.2x
EV/EBITDA 37.0x 20.7x 29.6x
EV/EBIT 46.1x 27.4x 31.1x
EV/Revenue 13.1x 6.9x 15.5x
EV/FCF 42.1x 33.5x 68.0x
EV/Operating cash flow 37.0x 26.4x 43.6x
PEG (3Y EPS CAGR) 2.06 -1.92 0.57

Growth

14 metrics
MetricISRGJNJLLY
Revenue growth (1Y) 20.5% 7.8% 45.5%
Revenue CAGR (3Y) 19.1% 5.9% 39.2%
Gross profit growth (1Y) 21.9% 7.0% 46.6%
Gross profit CAGR (3Y) 19.5% 5.1% 42.0%
Operating income growth (1Y) 16.6% 7.4% 67.5%
Operating income CAGR (3Y) 24.8% 1.4% 66.4%
Net income growth (1Y) 7.5% -35.9% 49.8%
Net income CAGR (3Y) 24.4% -22.5% 76.8%
EPS growth (1Y) 10.8% -36.4% 50.7%
EPS CAGR (3Y) 25.7% -21.5% 77.2%
Operating cash flow growth (1Y) 38.1% 8.1% 90.8%
Operating cash flow CAGR (3Y) 26.4% 12.4% 70.2%
Free cash flow growth (1Y) 58.4% 5.1% 112.1%
Free cash flow CAGR (3Y) 42.0% 14.5% 80.6%

Profitability

14 metrics
MetricISRGJNJLLY
Gross margin 67.2% 67.6% 83.6%
EBITDA margin 35.3% 33.5% 52.2%
Operating margin 28.4% 25.4% 49.7%
Pretax margin 31.3% 17.9% 40.2%
Net margin 25.5% 16.2% 31.9%
FCF margin 31.1% 20.7% 22.7%
Operating cash flow margin 35.3% 26.3% 35.4%
Return on equity 17.3% 19.3% 74.4%
Return on assets 14.8% 8.1% 19.0%
Return on invested capital – 17.6% 38.2%
Return on capital employed 18.7% 17.5% 43.7%
Asset turnover 0.6x 0.5x 0.6x
Cash conversion (OCF / net income) 1.4x 1.6x 1.1x
Stock comp / revenue 7.2% 1.4% 0.8%

Financial Health

11 metrics
MetricISRGJNJLLY
Debt / assets – 22.6% 33.4%
Debt / equity – 0.5x 1.2x
Net debt / EBITDA – 0.8x 1.0x
Debt / FCF – 2.2x 2.5x
Liabilities / assets 16.7% 58.7% 72.8%
Equity / assets 83.3% 41.3% 27.2%
Interest coverage – 25.6x –
Current ratio 3.3x 1.0x 1.4x
Quick ratio 2.3x 0.7x 0.6x
Cash ratio 1.6x 0.3x 0.1x
Altman Z-score 30.73 5.55 9.24

Shareholder Returns

7 metrics
MetricISRGJNJLLY
Dividend yield – 1.9% 0.5%
Net buyback yield 2.7% 0.6% 0.5%
Shareholder yield 2.7% 2.5% 0.9%
Payout ratio (earnings) – 79.0% –
Payout ratio (FCF) – 61.8% –
Dividend growth (1Y) – 3.9% –
Dividend CAGR (3Y) – 1.0% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusISRGJNJLLY
Forward P/E 39.1xFY2026 25.7xFY2026 42.4xFY2026
EPS, next fiscal year $11.47FY2026 $10.72FY2026 $32.40FY2026
EPS growth, next FY +28.4%FY2026 -0.6%FY2026 +33.8%FY2026
EPS growth, the year after +4.5% +5.9% +42.2%
Revenue, next fiscal year $11.60BFY2026 $106.54BFY2026 $85.28BFY2026
Revenue growth, next FY +15.3%FY2026 +13.1%FY2026 +30.8%FY2026
Revenue growth, the year after +11.3% +7.0% +17.4%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersISRGJNJLLY
Held by institutions 86.2% 74.7% 83.7%
Institutions holding 2,237 4,692 4,629
Change in shares held, QoQ +4.6% +1.8% +1.5%
Institutions buying 1,072 2,294 2,633
Institutions selling 877 1,896 1,469
Buyers to sellers 1.22 1.21 1.79

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ISRGJNJLLY
ISRG 1.00 0.10 0.23
JNJ 0.10 1.00 0.46
LLY 0.23 0.46 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ISRG, JNJ and LLY?

Eli Lilly (LLY) is the largest by market capitalisation: Intuitive Surgical (ISRG) $150.86B, Johnson & Johnson (JNJ) $660.04B, Eli Lilly (LLY) $1.26T.

Which stock is cheaper, ISRG, JNJ and LLY?

Johnson & Johnson (JNJ) trades on the lowest price-to-earnings ratio (Intuitive Surgical (ISRG) 51.0x, Johnson & Johnson (JNJ) 41.0x, Eli Lilly (LLY) 45.8x). On next year's consensus earnings, Johnson & Johnson (JNJ) is cheapest (Intuitive Surgical (ISRG) 39.1x, Johnson & Johnson (JNJ) 25.7x, Eli Lilly (LLY) 42.4x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Eli Lilly (LLY) grew revenue fastest over the trailing twelve months: Intuitive Surgical (ISRG) +20.5%, Johnson & Johnson (JNJ) +7.8%, Eli Lilly (LLY) +45.5%.

Which company is more profitable?

Eli Lilly (LLY) has the highest net margin (Intuitive Surgical (ISRG) 25.5%, Johnson & Johnson (JNJ) 16.2%, Eli Lilly (LLY) 31.9%). On return on invested capital, Eli Lilly (LLY) leads (Johnson & Johnson (JNJ) 17.6%, Eli Lilly (LLY) 38.2%).

Which stock has performed better?

Over the past year Eli Lilly (LLY) returned the most: Intuitive Surgical (ISRG) -16.5%, Johnson & Johnson (JNJ) +47.5%, Eli Lilly (LLY) +68.8%. Over five years, Eli Lilly (LLY) compounded fastest (Intuitive Surgical (ISRG) +4.4%/yr, Johnson & Johnson (JNJ) +11.1%/yr, Eli Lilly (LLY) +40.1%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Intuitive Surgical (ISRG) 0.00%, Johnson & Johnson (JNJ) 0.02%, Eli Lilly (LLY) 0.00%. Intuitive Surgical (ISRG) and Eli Lilly (LLY) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Johnson & Johnson (JNJ) has been the steadiest (Intuitive Surgical (ISRG) 34.6%, Johnson & Johnson (JNJ) 20.9%, Eli Lilly (LLY) 35.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ISRG, JNJ and LLY?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Eli Lilly (LLY) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.