ISRG vs JNJ vs EW Stock Comparison

Intuitive Surgical, Johnson & Johnson and Edwards Lifesciences Prices as of Oct 28, 2026 Peers: Industry group
ISRG Intuitive Surgical Inc
$444.18 +7.1% 1M -18.6% 1Y
Market cap
$153.95B
P/E
52.4x
Revenue (TTM)
$11.58B
Div. yield
–
Medical Devices Healthcare
3 wins
JNJ Johnson & Johnson
$271.21 -0.3% 1M +45.1% 1Y
Market cap
$652.89B
P/E
40.6x
Revenue (TTM)
$99.34B
Div. yield
1.95%
Pharmaceuticals Healthcare
7 wins
EW Edwards Lifesciences Corp
$91.80 +5.7% 1M +11.7% 1Y
Market cap
$52.93B
P/E
52.7x
Revenue (TTM)
$6.51B
Div. yield
–
Medical Devices Healthcare
1 win

Head to Head

11 decided of 12

Johnson & Johnson leads on 7 of the 12 questions below (Johnson & Johnson 7, Intuitive Surgical 3, Edwards Lifesciences 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionISRGJNJEWLeader
Larger companyMarket capitalisation $153.95B $652.89B $52.93B JNJ
Cheaper on earningsLower P/E, profitable companies only 52.4x 40.6x 52.7x JNJ
Cheaper on forward earningsLower price / next fiscal year consensus EPS 38.7x 25.3x 32.4x JNJ
Faster revenue growthRevenue growth, trailing twelve months +20.5% +7.8% +14.6% ISRG
More profitableNet margin, trailing twelve months 25.5% 16.2% 15.4% ISRG
Better return on capitalReturn on invested capital — 17.6% 9.0% JNJ
Less leveragedLower net debt / EBITDA — 0.8x -2.3x EW
Higher dividend yieldTrailing dividend yield — 1.95% — –
Better 1-year returnPrice return, last 12 months -18.6% +45.1% +11.7% JNJ
Better 5-year returnAnnualised price return, 5 years +4.2%/yr +10.7%/yr -5.2%/yr JNJ
Less volatileAnnualised volatility, 1 year 34.6% 20.8% 24.7% JNJ
Higher overall scoreMean of the five percentile scores vs peers 80/100 68/100 78/100 ISRG

Percentile Scorecard

ISRGJNJEW

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisISRGJNJEW
Valuation 53 #107 of 227 87 #82 of 625 64 #83 of 227
Growth 80 #44 of 219 42 #351 of 602 54 #101 of 219
Profitability 98 #6 of 205 93 #38 of 549 95 #12 of 205
Financial Health 78 #54 of 237 42 #379 of 654 87 #31 of 237
Shareholder Returns 91 #13 of 135 75 #92 of 367 88 #17 of 135
Overall 80 68 78
  • ISRG ranked among 247 companies in Medical Devices and Diagnostics
  • JNJ ranked among 672 companies in Pharmaceuticals and Biotechnology
  • EW ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodISRGJNJEWSPY
1 month +7.1%-0.3%+5.7% +0.9%
3 months +25.8%+2.1%+7.0% +5.9%
6 months -2.1%+19.3%+13.0% +8.5%
Year to date -21.6%+31.1%+7.7% +13.3%
1 year -18.6%+45.1%+11.7% +12.4%
3 years +71.5%+86.3%+48.8% +88.1%
3 years, per year +19.7%+23.1%+14.2% +23.5%
5 years +23.0%+66.5%-23.4% +68.2%
5 years, per year +4.2%+10.7%-5.2% +11.0%
10 years +499.8%+135.2%+186.4% +263.4%
10 years, per year +19.6%+8.9%+11.1% +13.8%

Risk

MeasureISRGJNJEWSPY
Volatility, 1Y 34.6%20.8%24.7% 12.7%
Downside volatility, 1Y 37.4%20.0%24.5% 12.7%
Beta vs S&P 500, 1Y 0.89-0.220.58 1.00
Return / volatility, 1Y -0.542.170.47 0.98
Max drawdown, 5Y -49.9%-23.6%-54.3% -25.4%
From 52-week high -25.1%-2.6%-3.5% -0.9%
52-week high $592.85$278.47$95.17 $779.14
52-week low $332.02$186.00$75.87 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleISRGJNJEW
P/E now vs peer median 52.4xmedian 28.8x 40.6xmedian 17.4x 52.7xmedian 28.8x
P/S now vs peer median 13.3xmedian 3.0x 6.6xmedian 9.1x 8.1xmedian 3.0x
EV/EBITDA now vs peer median 36.6xmedian 17.4x 20.4xmedian 17.1x 30.5xmedian 17.4x
P/FCF now vs peer median 42.8xmedian 25.7x 31.7xmedian 19.0x 36.9xmedian 25.7x
P/B now vs peer median 9.6xmedian 2.4x 8.0xmedian 2.2x 4.9xmedian 2.4x
PEG now vs peer median 2.04median 1.03 -1.89median 0.34 -6.14median 1.03

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsISRGJNJEW
Revenue $11.58B $99.34B $6.51B
Gross profit $7.78B $67.11B $5.07B
Operating income $3.28B $25.19B $1.45B
Net income $2.97B $16.10B $1.00B
Free cash flow $3.60B $20.59B $1.43B
R&D $1.49B $16.08B $1.09B
EPS (diluted) $8.41 $6.57 $1.74
Cash & equivalents $2.98B $16.91B $2.91B
Total debt – $44.65B $598.70M
Shares (diluted) 351.60M 2.45B 577.60M
Enterprise value $134.37B $572.75B $37.05B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricISRGJNJEW
P/E 52.4x 40.6x 52.7x
P/FCF 42.8x 31.7x 36.9x
P/Operating cash flow 37.6x 25.0x 30.8x
P/S 13.3x 6.6x 8.1x
P/B 9.6x 8.0x 4.9x
P/Tangible book 10.3x 18.7x 5.7x
EV/EBITDA 36.6x 20.4x 30.5x
EV/EBIT 45.6x 27.0x 34.0x
EV/Revenue 12.9x 6.8x 7.6x
EV/FCF 41.7x 33.0x 34.4x
EV/Operating cash flow 36.7x 26.0x 28.6x
PEG (3Y EPS CAGR) 2.04 -1.89 -6.14

Growth

14 metrics
MetricISRGJNJEW
Revenue growth (1Y) 20.5% 7.8% 14.6%
Revenue CAGR (3Y) 19.1% 5.9% 15.3%
Gross profit growth (1Y) 21.9% 7.0% 13.0%
Gross profit CAGR (3Y) 19.5% 5.1% 11.9%
Operating income growth (1Y) 16.6% 7.4% -1.4%
Operating income CAGR (3Y) 24.8% 1.4% 5.0%
Net income growth (1Y) 7.5% -35.9% -75.8%
Net income CAGR (3Y) 24.4% -22.5% -10.2%
EPS growth (1Y) 10.8% -36.4% -75.3%
EPS CAGR (3Y) 25.7% -21.5% -8.6%
Operating cash flow growth (1Y) 38.1% 8.1% 116.4%
Operating cash flow CAGR (3Y) 26.4% 12.4% 22.3%
Free cash flow growth (1Y) 58.4% 5.1% 143.9%
Free cash flow CAGR (3Y) 42.0% 14.5% 26.9%

Profitability

14 metrics
MetricISRGJNJEW
Gross margin 67.2% 67.6% 77.8%
EBITDA margin 35.3% 33.5% 24.8%
Operating margin 28.4% 25.4% 22.3%
Pretax margin 31.3% 17.9% 21.8%
Net margin 25.5% 16.2% 15.4%
FCF margin 31.1% 20.7% 22.0%
Operating cash flow margin 35.3% 26.3% 26.4%
Return on equity 17.3% 19.3% 9.5%
Return on assets 14.8% 8.1% 7.4%
Return on invested capital – 17.6% 9.0%
Return on capital employed 18.7% 17.5% 12.0%
Asset turnover 0.6x 0.5x 0.5x
Cash conversion (OCF / net income) 1.4x 1.6x 1.7x
Stock comp / revenue 7.2% 1.4% 2.6%

Financial Health

11 metrics
MetricISRGJNJEW
Debt / assets – 22.6% 4.3%
Debt / equity – 0.5x 0.1x
Net debt / EBITDA – 0.8x -2.3x
Debt / FCF – 2.2x 0.4x
Liabilities / assets 16.7% 58.7% 22.7%
Equity / assets 83.3% 41.3% 77.3%
Interest coverage – 25.6x –
Current ratio 3.3x 1.0x 4.5x
Quick ratio 2.3x 0.7x 3.5x
Cash ratio 1.6x 0.3x 2.8x
Altman Z-score 30.44 5.50 12.88

Shareholder Returns

7 metrics
MetricISRGJNJEW
Dividend yield – 1.9% –
Net buyback yield 2.8% 0.6% 1.9%
Shareholder yield 2.8% 2.6% 1.9%
Payout ratio (earnings) – 79.0% –
Payout ratio (FCF) – 61.8% –
Dividend growth (1Y) – 3.9% –
Dividend CAGR (3Y) – 1.0% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusISRGJNJEW
Forward P/E 38.7xFY2026 25.3xFY2026 32.4xFY2026
EPS, next fiscal year $11.47FY2026 $10.72FY2026 $2.83FY2026
EPS growth, next FY +28.4%FY2026 -0.6%FY2026 +10.5%FY2026
EPS growth, the year after +4.5% +5.9% +12.7%
Revenue, next fiscal year $11.60BFY2026 $106.54BFY2026 $7.24BFY2026
Revenue growth, next FY +15.3%FY2026 +13.1%FY2026 +19.2%FY2026
Revenue growth, the year after +11.3% +7.0% -2.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersISRGJNJEW
Held by institutions 86.2% 74.7% 90.6%
Institutions holding 2,236 4,691 1,323
Change in shares held, QoQ +4.6% +1.8% +20.4%
Institutions buying 1,071 2,294 641
Institutions selling 877 1,895 453
Buyers to sellers 1.22 1.21 1.42

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ISRGJNJEW
ISRG 1.00 0.10 0.45
JNJ 0.10 1.00 0.14
EW 0.45 0.14 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ISRG, JNJ and EW?

Johnson & Johnson (JNJ) is the largest by market capitalisation: Intuitive Surgical (ISRG) $153.95B, Johnson & Johnson (JNJ) $652.89B, Edwards Lifesciences (EW) $52.93B.

Which stock is cheaper, ISRG, JNJ and EW?

Johnson & Johnson (JNJ) trades on the lowest price-to-earnings ratio (Intuitive Surgical (ISRG) 52.4x, Johnson & Johnson (JNJ) 40.6x, Edwards Lifesciences (EW) 52.7x). On next year's consensus earnings, Johnson & Johnson (JNJ) is cheapest (Intuitive Surgical (ISRG) 38.7x, Johnson & Johnson (JNJ) 25.3x, Edwards Lifesciences (EW) 32.4x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Intuitive Surgical (ISRG) grew revenue fastest over the trailing twelve months: Intuitive Surgical (ISRG) +20.5%, Johnson & Johnson (JNJ) +7.8%, Edwards Lifesciences (EW) +14.6%.

Which company is more profitable?

Intuitive Surgical (ISRG) has the highest net margin (Intuitive Surgical (ISRG) 25.5%, Johnson & Johnson (JNJ) 16.2%, Edwards Lifesciences (EW) 15.4%). On return on invested capital, Johnson & Johnson (JNJ) leads (Johnson & Johnson (JNJ) 17.6%, Edwards Lifesciences (EW) 9.0%).

Which stock has performed better?

Over the past year Johnson & Johnson (JNJ) returned the most: Intuitive Surgical (ISRG) -18.6%, Johnson & Johnson (JNJ) +45.1%, Edwards Lifesciences (EW) +11.7%. Over five years, Johnson & Johnson (JNJ) compounded fastest (Intuitive Surgical (ISRG) +4.2%/yr, Johnson & Johnson (JNJ) +10.7%/yr, Edwards Lifesciences (EW) -5.2%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Johnson & Johnson (JNJ) 1.95%. Intuitive Surgical (ISRG) and Edwards Lifesciences (EW) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Johnson & Johnson (JNJ) has been the steadiest (Intuitive Surgical (ISRG) 34.6%, Johnson & Johnson (JNJ) 20.8%, Edwards Lifesciences (EW) 24.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ISRG, JNJ and EW?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Johnson & Johnson (JNJ) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.