IOVA vs NTLA Stock Comparison

Iovance Biotherapeutics and Intellia Therapeutics Prices as of Oct 28, 2026 Peers: Industry group

Head to Head

7 decided of 12

Iovance Biotherapeutics leads on 6 of the 12 questions below (Iovance Biotherapeutics 6, Intellia Therapeutics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionIOVANTLALeader
Larger companyMarket capitalisation $6.71B $1.87B IOVA
Cheaper on earningsLower P/E, profitable companies only -23.0x -4.4x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — –
Faster revenue growthRevenue growth, trailing twelve months +34.5% +12.6% IOVA
More profitableNet margin, trailing twelve months -89.1% -672.2% IOVA
Better return on capitalReturn on invested capital — — –
Less leveragedLower net debt / EBITDA — — –
Higher dividend yieldTrailing dividend yield — — –
Better 1-year returnPrice return, last 12 months +576.3% -4.6% IOVA
Better 5-year returnAnnualised price return, 5 years -9.4%/yr -36.9%/yr IOVA
Less volatileAnnualised volatility, 1 year 99.0% 80.0% NTLA
Higher overall scoreMean of the five percentile scores vs peers 64/100 50/100 IOVA

Percentile Scorecard

IOVANTLA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisIOVANTLA
Valuation 67 #208 of 625 34 #412 of 625
Growth 81 #113 of 602 64 #220 of 602
Profitability 63 #206 of 549 39 #338 of 549
Financial Health 64 #235 of 654 72 #182 of 654
Shareholder Returns 45 #204 of 367 40 #220 of 367
Overall 64 50
  • IOVA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • NTLA ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodIOVANTLASPY
1 month +34.8%+16.6% +0.9%
3 months +224.8%+23.3% +5.9%
6 months +347.4%+7.1% +8.5%
Year to date +442.5%+48.2% +13.3%
1 year +576.3%-4.6% +12.4%
3 years +323.1%-42.5% +88.1%
3 years, per year +61.8%-16.8% +23.5%
5 years -39.1%-90.0% +68.2%
5 years, per year -9.4%-36.9% +11.0%
10 years +137.0%+2.8% +263.4%
10 years, per year +9.0%+0.3% +13.8%

Risk

MeasureIOVANTLASPY
Volatility, 1Y 99.0%80.0% 12.7%
Downside volatility, 1Y 71.1%82.2% 12.7%
Beta vs S&P 500, 1Y 1.292.46 1.00
Return / volatility, 1Y 5.82-0.06 0.98
Max drawdown, 5Y -93.4%-95.5% -25.4%
From 52-week high -0.3%-25.3% -0.9%
52-week high $14.86$17.84 $779.14
52-week low $1.81$8.04 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleIOVANTLA
P/E now vs peer median -23.0xmedian 17.4x -4.4xmedian 17.4x
P/S now vs peer median 20.6xmedian 9.1x 31.3xmedian 9.1x
EV/EBITDA now vs peer median -24.2xmedian 17.1x -3.4xmedian 17.1x
P/FCF now vs peer median -22.6xmedian 19.0x -5.3xmedian 19.0x
P/B now vs peer median 9.1xmedian 2.2x 2.6xmedian 2.2x
PEG now vs peer median -0.77median 0.34 -0.27median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsIOVANTLA
Revenue $324.97M $59.51M
Gross profit $157.29M –
Operating income -$301.31M -$423.48M
Net income -$289.51M -$399.98M
Free cash flow -$296.40M -$348.69M
R&D $267.72M $346.73M
EPS (diluted) $-0.64 $-3.00
Cash & equivalents $110.80M $106.13M
Shares (diluted) 450.19M 133.48M
Enterprise value $5.50B $90.37M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricIOVANTLA
P/E -23.0x -4.4x
P/FCF -22.6x -5.3x
P/Operating cash flow -25.4x -5.4x
P/S 20.6x 31.3x
P/B 9.1x 2.6x
P/Tangible book 14.2x 2.6x
EV/EBITDA -24.2x -3.4x
EV/EBIT -21.3x -3.4x
EV/Revenue 19.7x 24.0x
EV/FCF -21.6x -4.1x
EV/Operating cash flow -24.3x -4.1x
PEG (3Y EPS CAGR) -0.77 -0.27

Growth

14 metrics
MetricIOVANTLA
Revenue growth (1Y) 34.5% 12.6%
Revenue CAGR (3Y) 1,009% 3.9%
Gross profit growth (1Y) 95.1% –
Gross profit CAGR (3Y) – –
Operating income growth (1Y) 26.6% 17.3%
Operating income CAGR (3Y) 11.1% 2.7%
Net income growth (1Y) 25.8% 16.7%
Net income CAGR (3Y) 11.6% 4.1%
EPS growth (1Y) 44.8% 35.3%
EPS CAGR (3Y) 29.9% 16.5%
Operating cash flow growth (1Y) 12.9% 17.2%
Operating cash flow CAGR (3Y) 7.6% 2.0%
Free cash flow growth (1Y) 8.4% 17.3%
Free cash flow CAGR (3Y) 5.8% 3.2%

Profitability

14 metrics
MetricIOVANTLA
Gross margin 48.4% –
EBITDA margin -81.4% -696.4%
Operating margin -92.7% -711.7%
Pretax margin -90.4% -671.0%
Net margin -89.1% -672.2%
FCF margin -91.2% -586.0%
Operating cash flow margin -81.3% -582.5%
Return on equity -39.7% -59.2%
Return on assets -31.4% -49.4%
Return on invested capital – –
Return on capital employed -37.0% -58.1%
Asset turnover 0.4x 0.1x
Cash conversion (OCF / net income) 0.9x 0.9x
Stock comp / revenue 14.4% 114.1%

Financial Health

11 metrics
MetricIOVANTLA
Debt / assets – –
Debt / equity – –
Net debt / EBITDA – –
Debt / FCF – –
Liabilities / assets 19.6% 15.1%
Equity / assets 80.4% 84.9%
Interest coverage – –
Current ratio 4.3x 6.6x
Quick ratio 3.7x 5.6x
Cash ratio 2.8x 5.5x
Altman Z-score 17.73 3.15

Shareholder Returns

7 metrics
MetricIOVANTLA
Dividend yield – –
Net buyback yield -4.4% -7.1%
Shareholder yield -4.4% -7.1%
Payout ratio (earnings) – –
Payout ratio (FCF) – –
Dividend growth (1Y) – –
Dividend CAGR (3Y) – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusIOVANTLA
EPS, next fiscal year $-0.47FY2026 $-3.38FY2026
Revenue, next fiscal year $434.71MFY2026 $48.94MFY2026
Revenue growth, next FY +65.0%FY2026 -27.7%FY2026
Revenue growth, the year after +33.0% +158.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersIOVANTLA
Held by institutions 63.3% 100.0%
Institutions holding 292 329
Change in shares held, QoQ +6.5% +30.5%
Institutions buying 174 195
Institutions selling 66 78
Buyers to sellers 2.64 2.50

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

IOVANTLA
IOVA 1.00 0.26
NTLA 0.26 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, IOVA and NTLA?

Iovance Biotherapeutics (IOVA) is the largest by market capitalisation: Iovance Biotherapeutics (IOVA) $6.71B, Intellia Therapeutics (NTLA) $1.87B.

Which company is growing faster?

Iovance Biotherapeutics (IOVA) grew revenue fastest over the trailing twelve months: Iovance Biotherapeutics (IOVA) +34.5%, Intellia Therapeutics (NTLA) +12.6%.

Which company is more profitable?

Iovance Biotherapeutics (IOVA) has the highest net margin (Iovance Biotherapeutics (IOVA) -89.1%, Intellia Therapeutics (NTLA) -672.2%).

Which stock has performed better?

Over the past year Iovance Biotherapeutics (IOVA) returned the most: Iovance Biotherapeutics (IOVA) +576.3%, Intellia Therapeutics (NTLA) -4.6%. Over five years, Iovance Biotherapeutics (IOVA) compounded fastest (Iovance Biotherapeutics (IOVA) -9.4%/yr, Intellia Therapeutics (NTLA) -36.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Intellia Therapeutics (NTLA) has been the steadiest (Iovance Biotherapeutics (IOVA) 99.0%, Intellia Therapeutics (NTLA) 80.0%). Volatility measures how widely the price swings, not the risk of the business.

Do IOVA and NTLA move together?

Their daily returns over the past year have a correlation of 0.26, a weak relationship. Holding both diversifies more than two closely linked stocks would.

Which is the better stock, IOVA and NTLA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Iovance Biotherapeutics (IOVA) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.