IMTX vs LEGN vs TSHA Stock Comparison

Immatics, Legend Biotech and Taysha Gene Therapies Prices as of Oct 29, 2026 Peers: Industry group
IMTX Immatics N.V.
$7.31 -14.6% 1M -29.3% 1Y
Market cap
$840.53M
P/E
–
Revenue (TTM)
$48.61M
Div. yield
–
Gene and Cell Therapy Healthcare
2 wins
LEGN Legend Biotech Corp
$22.30 +18.5% 1M -30.6% 1Y
Market cap
$3.94B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
4 wins

Head to Head

8 decided of 12

Legend Biotech leads on 4 of the 12 questions below (Legend Biotech 4, Taysha Gene Therapies 2, Immatics 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionIMTXLEGNTSHALeader
Larger companyMarket capitalisation $840.53M $3.94B $1.51B LEGN
Cheaper on earningsLower P/E, profitable companies only -3.5x -42.9x -10.1x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months -65.4% +59.5% -32.3% LEGN
More profitableNet margin, trailing twelve months -495.7% -7.2% -2,728.0% LEGN
Better return on capitalReturn on invested capital — -4.2% — –
Less leveragedLower net debt / EBITDA — 28.0x 2.7x TSHA
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -29.3% -30.6% -15.8% TSHA
Better 5-year returnAnnualised price return, 5 years -12.6%/yr -15.7%/yr -23.1%/yr IMTX
Less volatileAnnualised volatility, 1 year 57.6% 72.3% 71.5% IMTX
Higher overall scoreMean of the five percentile scores vs peers 36/100 73/100 49/100 LEGN

Percentile Scorecard

IMTXLEGNTSHA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisIMTXLEGNTSHA
Valuation 29 #442 of 624 89 #70 of 624 45 #343 of 624
Growth 4 #577 of 601 97 #20 of 601 16 #503 of 601
Profitability 45 #296 of 541 80 #108 of 541 28 #390 of 541
Financial Health 75 #166 of 647 54 #299 of 647 75 #160 of 647
Shareholder Returns 25 #268 of 359 44 #201 of 359 78 #79 of 359
Overall 36 73 49
  • IMTX ranked among 671 companies in Pharmaceuticals and Biotechnology
  • LEGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • TSHA ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodIMTXLEGNTSHASPY
1 month -14.6%+18.5%-15.4% +0.7%
3 months -20.5%+17.1%-28.2% +3.7%
6 months -33.5%-5.2%-34.0% +7.1%
Year to date -30.4%+2.6%-23.3% +12.8%
1 year -29.3%-30.6%-15.8% +11.9%
3 years -0.7%-66.0%+86.7% +85.2%
3 years, per year -0.2%-30.2%+23.2% +22.8%
5 years -49.0%-57.5%-73.0% +67.6%
5 years, per year -12.6%-15.7%-23.1% +10.9%

Risk

MeasureIMTXLEGNTSHASPY
Volatility, 1Y 57.6%72.3%71.5% 12.7%
Downside volatility, 1Y 59.4%62.7%69.5% 12.6%
Beta vs S&P 500, 1Y 1.360.441.82 1.00
Return / volatility, 1Y -0.51-0.42-0.22 0.94
Max drawdown, 5Y -75.7%-78.2%-96.5% -25.4%
From 52-week high -38.4%-38.5%-39.5% -1.2%
52-week high $11.87$36.28$6.98 $779.14
52-week low $6.73$16.65$3.51 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleIMTXLEGNTSHA
P/E now vs peer median -3.7xmedian 17.8x -44.8xmedian 17.8x -10.4xmedian 17.8x
P/S now vs peer median 20.2xmedian 9.1x 3.2xmedian 9.1x 250.3xmedian 9.1x
EV/EBITDA now vs peer median -2.1xmedian 15.0x -195.0xmedian 15.0x -6.4xmedian 15.0x
P/FCF now vs peer median -4.0xmedian 21.7x -63.6xmedian 21.7x -10.4xmedian 21.7x
P/B now vs peer median 2.1xmedian 2.2x 3.3xmedian 2.2x 3.5xmedian 2.2x
PEG now vs peer median 0.16median 0.35 -0.95median 0.35 -0.26median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsIMTXLEGNTSHA
Revenue $48.61M $1.27B $5.49M
Gross profit – $727.10M –
Operating income -$264.59M -$55.25M -$153.16M
Net income -$240.97M -$80.39M -$149.63M
Free cash flow -$244.28M -$64.60M -$132.57M
R&D $254.77M $396.15M $123.14M
EPS (diluted) $-1.97 $-0.50 $-0.41
Cash & equivalents $265.52M $672.90M $455.41M
Total debt – $1.06B $49.26M
Shares (diluted) 122.35M 184.32M 369.04M
Enterprise value -$1.19B $1.44B $158.43M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricIMTXLEGNTSHA
P/E -3.7x -44.8x -10.4x
P/FCF -4.0x -63.6x -10.4x
P/Operating cash flow -4.1x -46.0x -10.4x
P/S 20.2x 3.2x 250.3x
P/B 2.1x 3.3x 3.5x
P/Tangible book 2.2x 3.3x 3.5x
EV/EBITDA -2.1x -195.0x -6.4x
EV/EBIT -2.0x -65.0x -6.3x
EV/Revenue 10.9x 2.8x 176.2x
EV/FCF -2.2x -55.6x -7.3x
EV/Operating cash flow -2.2x -40.2x -7.3x
PEG (3Y EPS CAGR) 0.16 -0.95 -0.26

Growth

14 metrics
MetricIMTXLEGNTSHA
Revenue growth (1Y) -65.4% 59.5% -32.3%
Revenue CAGR (3Y) -47.1% 97.6% -9.1%
Gross profit growth (1Y) – 42.4% –
Gross profit CAGR (3Y) – 147.5% –
Operating income growth (1Y) -176.1% 75.3% -62.9%
Operating income CAGR (3Y) -58.8% 49.1% -8.7%
Net income growth (1Y) -187.4% 75.3% -61.4%
Net income CAGR (3Y) -37.5% 46.7% -6.5%
EPS growth (1Y) -180.7% 72.0% -30.3%
EPS CAGR (3Y) -23.8% 47.0% 40.5%
Operating cash flow growth (1Y) -33.6% 67.5% -61.0%
Operating cash flow CAGR (3Y) -39.1% 37.1% -35.6%
Free cash flow growth (1Y) -29.2% 77.8% -60.6%
Free cash flow CAGR (3Y) -30.7% 44.5% -29.4%

Profitability

14 metrics
MetricIMTXLEGNTSHA
Gross margin – 57.2% –
EBITDA margin -515.5% -1.5% -2,770%
Operating margin -544.3% -4.3% -2,792%
Pretax margin -496.3% -4.4% -2,593%
Net margin -495.7% -7.2% -2,728%
FCF margin -502.6% -5.1% -2,417%
Operating cash flow margin -493.8% -7.0% -2,410%
Return on equity -49.2% -8.3% -47.5%
Return on assets -40.9% -5.5% -36.9%
Return on invested capital – -4.2% –
Return on capital employed -50.5% -4.3% -42.6%
Asset turnover 0.1x 0.8x 0.0x
Cash conversion (OCF / net income) 1.0x 1.1x 0.9x
Stock comp / revenue 42.1% 5.2% 331.3%

Financial Health

11 metrics
MetricIMTXLEGNTSHA
Debt / assets – 8.9% 10.5%
Debt / equity – 0.1x 0.1x
Net debt / EBITDA – 28.0x 2.7x
Debt / FCF – -2.4x -0.4x
Liabilities / assets 17.7% 29.8% 17.7%
Equity / assets 82.3% 70.2% 82.3%
Interest coverage -3.2x -4.8x -3,647x
Current ratio 7.5x 3.0x 17.8x
Quick ratio 7.0x 1.7x 17.5x
Cash ratio 6.9x 1.7x 17.5x
Altman Z-score 2.80 6.90 7.57

Shareholder Returns

7 metrics
MetricIMTXLEGNTSHA
Dividend yield – – –
Net buyback yield -15.4% -5.2% -0.2%
Shareholder yield -15.4% -5.2% -0.2%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusIMTXLEGNTSHA
EPS, next fiscal year $-2.10FY2026 $-0.04FY2026 $-0.47FY2026
Revenue, next fiscal year $40.64MFY2026 $1.37BFY2026 $1.96MFY2026
Revenue growth, next FY -28.4%FY2026 +32.9%FY2026 -80.0%FY2026
Revenue growth, the year after -11.9% +35.9% +1,298.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersIMTXLEGNTSHA
Held by institutions 81.6% 55.9% 81.2%
Institutions holding 83 218 209
Change in shares held, QoQ -7.8% +7.3% +12.7%
Institutions buying 37 117 140
Institutions selling 33 78 42
Buyers to sellers 1.12 1.50 3.33

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

IMTXLEGNTSHA
IMTX 1.00 0.07 0.48
LEGN 0.07 1.00 0.16
TSHA 0.48 0.16 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, IMTX, LEGN and TSHA?

Legend Biotech (LEGN) is the largest by market capitalisation: Immatics (IMTX) $840.53M, Legend Biotech (LEGN) $3.94B, Taysha Gene Therapies (TSHA) $1.51B.

Which company is growing faster?

Legend Biotech (LEGN) grew revenue fastest over the trailing twelve months: Immatics (IMTX) -65.4%, Legend Biotech (LEGN) +59.5%, Taysha Gene Therapies (TSHA) -32.3%.

Which company is more profitable?

Legend Biotech (LEGN) has the highest net margin (Immatics (IMTX) -495.7%, Legend Biotech (LEGN) -7.2%, Taysha Gene Therapies (TSHA) -2,728.0%).

Which stock has performed better?

Over the past year Taysha Gene Therapies (TSHA) returned the most: Immatics (IMTX) -29.3%, Legend Biotech (LEGN) -30.6%, Taysha Gene Therapies (TSHA) -15.8%. Over five years, Immatics (IMTX) compounded fastest (Immatics (IMTX) -12.6%/yr, Legend Biotech (LEGN) -15.7%/yr, Taysha Gene Therapies (TSHA) -23.1%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Immatics (IMTX) has been the steadiest (Immatics (IMTX) 57.6%, Legend Biotech (LEGN) 72.3%, Taysha Gene Therapies (TSHA) 71.5%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, IMTX, LEGN and TSHA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Legend Biotech (LEGN) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.