IMMX vs IOVA vs LEGN Stock Comparison

Immix Biopharma, Iovance Biotherapeutics and Legend Biotech Prices as of Nov 5, 2026 Peers: Industry group
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IMMX Immix Biopharma, Inc.
$7.20 -25.3% 1M +136.1% 1Y
Market cap
$515.06M
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
LEGN Legend Biotech Corp
$22.54 +20.4% 1M -29.6% 1Y
Market cap
$4.15B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
6 wins

Head to Head

7 decided of 12

Legend Biotech leads on 6 of the 12 questions below (Legend Biotech 6, Iovance Biotherapeutics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionIMMXIOVALEGNLeader
Larger companyMarket capitalisation $515.06M $3.58B $4.15B LEGN
Cheaper on earningsLower P/E, profitable companies only -11.5x -16.0x -45.3x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months — +51.3% +59.5% LEGN
More profitableNet margin, trailing twelve months — -58.2% -7.2% LEGN
Better return on capitalReturn on invested capital — — -4.2% –
Less leveragedLower net debt / EBITDA — — -130.2x –
Higher dividend yieldTrailing dividend yield — — — –
Better 1-year returnPrice return, last 12 months +136.1% +327.6% -29.6% IOVA
Better 5-year returnAnnualised price return, 5 years — -20.9%/yr -14.3%/yr LEGN
Less volatileAnnualised volatility, 1 year 82.7% 109.9% 72.7% LEGN
Higher overall scoreMean of the five percentile scores vs peers 52/100 67/100 74/100 LEGN

Percentile Scorecard

IMMXIOVALEGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisIMMXIOVALEGN
Valuation 73 #175 of 634 70 #190 of 634 88 #77 of 634
Growth 5 #576 of 608 91 #58 of 608 96 #23 of 608
Profitability 78 #122 of 557 67 #182 of 557 80 #110 of 557
Financial Health 97 #21 of 654 68 #213 of 654 59 #267 of 654
Shareholder Returns 8 #373 of 403 39 #245 of 403 44 #225 of 403
Overall 52 67 74
  • IMMX ranked among 671 companies in Pharmaceuticals and Biotechnology
  • IOVA ranked among 671 companies in Pharmaceuticals and Biotechnology
  • LEGN ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodIMMXIOVALEGNSPY
1 month -25.3%-40.3%+20.4% -5.9%
3 months -28.4%+24.6%+16.9% -4.6%
6 months -24.5%+118.0%-21.1% +0.2%
Year to date +37.7%+183.5%+3.7% +7.5%
1 year +136.1%+327.6%-29.6% +8.2%
3 years +67.1%+79.2%-65.8% +68.3%
3 years, per year +18.7%+21.5%-30.1% +19.0%
5 years —-69.0%-53.7% +56.5%
5 years, per year —-20.9%-14.3% +9.4%
10 years —+33.4%— +251.5%
10 years, per year —+2.9%— +13.4%

Risk

MeasureIMMXIOVALEGNSPY
Volatility, 1Y 82.7%109.9%72.7% 13.6%
Downside volatility, 1Y 76.0%95.6%62.9% 14.2%
Beta vs S&P 500, 1Y 1.671.600.50 1.00
Return / volatility, 1Y 1.652.98-0.41 0.60
Max drawdown, 5Y -88.9%-93.4%-78.2% -25.4%
From 52-week high -50.2%-47.9%-37.9% -5.9%
52-week high $14.47$14.86$36.28 $779.14
52-week low $3.03$1.81$16.65 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleIMMXIOVALEGN
P/E now vs peer median -11.5xmedian 17.8x -16.0xmedian 17.8x -45.3xmedian 17.8x
P/S now vs peer median —median 8.1x 9.4xmedian 8.1x 3.3xmedian 8.1x
EV/EBITDA now vs peer median -6.8xmedian 15.7x -16.6xmedian 15.7x 917.1xmedian 15.7x
P/FCF now vs peer median -13.2xmedian 21.0x -16.6xmedian 21.0x -64.3xmedian 21.0x
P/B now vs peer median 2.2xmedian 2.0x 4.4xmedian 2.0x 3.4xmedian 2.0x
PEG now vs peer median -1.86median 0.36 -0.46median 0.36 -0.96median 0.36

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsIMMXIOVALEGN
Revenue – $378.98M $1.27B
Gross profit – $201.75M $727.10M
Operating income -$41.82M -$230.38M -$55.25M
Net income -$39.88M -$220.56M -$80.39M
Free cash flow -$39.09M -$216.07M -$64.60M
R&D $21.62M $241.88M $396.15M
EPS (diluted) $-0.63 $-0.48 $-0.50
Cash & equivalents $225.49M $57.93M $672.90M
Total debt – – $156.40M
Shares (diluted) 63.77M 455.92M 184.32M
Enterprise value $282.96M $2.30B $1.65B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricIMMXIOVALEGN
P/E -11.5x -16.0x -45.3x
P/FCF -13.2x -16.6x -64.3x
P/Operating cash flow -13.4x -18.9x -46.5x
P/S – 9.4x 3.3x
P/B 2.2x 4.4x 3.4x
P/Tangible book 2.2x 6.5x 3.4x
EV/EBITDA -6.8x -16.6x 917.1x
EV/EBIT -6.8x -13.9x -65.8x
EV/Revenue – 8.5x 2.9x
EV/FCF -7.2x -14.8x -56.3x
EV/Operating cash flow -7.3x -16.9x -40.7x
PEG (3Y EPS CAGR) -1.86 -0.46 -0.96

Growth

14 metrics
MetricIMMXIOVALEGN
Revenue growth (1Y) – 51.3% 59.5%
Revenue CAGR (3Y) – 712.3% 97.6%
Gross profit growth (1Y) – 144.4% 42.4%
Gross profit CAGR (3Y) – – 147.5%
Operating income growth (1Y) -75.8% 44.7% 75.3%
Operating income CAGR (3Y) -53.5% 19.8% 49.1%
Net income growth (1Y) -72.4% 44.5% 75.3%
Net income CAGR (3Y) -51.7% 20.1% 46.7%
EPS growth (1Y) 18.9% 55.7% 72.0%
EPS CAGR (3Y) 6.2% 35.0% 47.0%
Operating cash flow growth (1Y) -207.8% 41.2% 67.5%
Operating cash flow CAGR (3Y) -51.9% 18.9% 37.1%
Free cash flow growth (1Y) -190.0% 38.6% 77.8%
Free cash flow CAGR (3Y) -52.7% 17.0% 44.5%

Profitability

14 metrics
MetricIMMXIOVALEGN
Gross margin – 53.2% 57.2%
EBITDA margin – -50.9% 0.3%
Operating margin – -60.8% -4.3%
Pretax margin – -58.5% -4.4%
Net margin – -58.2% -7.2%
FCF margin – -57.0% -5.1%
Operating cash flow margin – -50.1% -7.0%
Return on equity -25.5% -28.5% -8.3%
Return on assets -23.8% -23.1% -5.5%
Return on invested capital – – -4.2%
Return on capital employed -26.4% -27.2% -4.3%
Asset turnover – 0.4x 0.8x
Cash conversion (OCF / net income) 1.0x 0.9x 1.1x
Stock comp / revenue – 12.3% 5.2%

Financial Health

11 metrics
MetricIMMXIOVALEGN
Debt / assets – – 8.9%
Debt / equity – – 0.1x
Net debt / EBITDA – – -130.2x
Debt / FCF – – -2.4x
Liabilities / assets 4.3% 18.0% 29.8%
Equity / assets 95.7% 82.0% 70.2%
Interest coverage – – -4.8x
Current ratio 25.1x 5.2x 3.0x
Quick ratio 25.0x 4.6x 1.7x
Cash ratio 25.0x 3.6x 1.7x
Altman Z-score – 8.06 6.95

Shareholder Returns

7 metrics
MetricIMMXIOVALEGN
Dividend yield – – –
Net buyback yield -48.3% -8.2% -5.2%
Shareholder yield -48.3% -8.2% -5.2%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusIMMXIOVALEGN
EPS, next fiscal year $-0.70FY2026 $-0.47FY2026 $-0.04FY2026
Revenue, next fiscal year $0.00FY2026 $435.90MFY2026 $1.37BFY2026
Revenue growth, next FY – +65.4%FY2026 +32.9%FY2026
Revenue growth, the year after – +33.1% +35.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersIMMXIOVALEGN
Held by institutions 78.6% 63.3% 55.9%
Institutions holding 110 292 218
Change in shares held, QoQ +107.6% +6.5% +7.3%
Institutions buying 81 174 117
Institutions selling 13 66 78
Buyers to sellers 6.23 2.64 1.50

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

IMMXIOVALEGN
IMMX 1.00 0.26 0.05
IOVA 0.26 1.00 0.14
LEGN 0.05 0.14 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, IMMX, IOVA and LEGN?

Legend Biotech (LEGN) is the largest by market capitalisation: Immix Biopharma (IMMX) $515.06M, Iovance Biotherapeutics (IOVA) $3.58B, Legend Biotech (LEGN) $4.15B.

Which company is growing faster?

Legend Biotech (LEGN) grew revenue fastest over the trailing twelve months: Iovance Biotherapeutics (IOVA) +51.3%, Legend Biotech (LEGN) +59.5%.

Which company is more profitable?

Legend Biotech (LEGN) has the highest net margin (Iovance Biotherapeutics (IOVA) -58.2%, Legend Biotech (LEGN) -7.2%).

Which stock has performed better?

Over the past year Iovance Biotherapeutics (IOVA) returned the most: Immix Biopharma (IMMX) +136.1%, Iovance Biotherapeutics (IOVA) +327.6%, Legend Biotech (LEGN) -29.6%. Over five years, Legend Biotech (LEGN) compounded fastest (Iovance Biotherapeutics (IOVA) -20.9%/yr, Legend Biotech (LEGN) -14.3%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Legend Biotech (LEGN) has been the steadiest (Immix Biopharma (IMMX) 82.7%, Iovance Biotherapeutics (IOVA) 109.9%, Legend Biotech (LEGN) 72.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, IMMX, IOVA and LEGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Legend Biotech (LEGN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.