ILMN vs TECH vs BIO Stock Comparison

Illumina, Bio-Techne and Bio-Rad Laboratories Prices as of Oct 28, 2026 Peers: Industry group
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ILMN Illumina, Inc.
$288.79 +6.2% 1M +195.3% 1Y
Market cap
$43.61B
P/E
52.9x
Revenue (TTM)
$4.49B
Div. yield
–
Life Sciences Tools Healthcare
6 wins
TECH BIO-TECHNE Corp
$72.69 +0.2% 1M +13.7% 1Y
Market cap
$11.35B
P/E
62.3x
Revenue (TTM)
$1.22B
Div. yield
0.44%
Life Sciences Tools Healthcare
3 wins

Head to Head

11 decided of 12

Illumina leads on 6 of the 12 questions below (Illumina 6, Bio-Techne 3, Bio-Rad Laboratories 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionILMNTECHBIOLeader
Larger companyMarket capitalisation $43.61B $11.35B $10.31B ILMN
Cheaper on earningsLower P/E, profitable companies only 52.9x 62.3x 46.4x BIO
Cheaper on forward earningsLower price / next fiscal year consensus EPS 57.9x 33.7x 38.8x TECH
Faster revenue growthRevenue growth, trailing twelve months +4.9% -0.4% +1.4% ILMN
More profitableNet margin, trailing twelve months 18.4% 15.0% 8.6% ILMN
Better return on capitalReturn on invested capital 15.1% 8.3% 0.4% ILMN
Less leveragedLower net debt / EBITDA 0.7x -0.2x — TECH
Higher dividend yieldTrailing dividend yield — 0.44% — –
Better 1-year returnPrice return, last 12 months +195.3% +13.7% +16.7% ILMN
Better 5-year returnAnnualised price return, 5 years -6.5%/yr -11.1%/yr -13.5%/yr ILMN
Less volatileAnnualised volatility, 1 year 50.4% 43.5% 37.0% BIO
Higher overall scoreMean of the five percentile scores vs peers 65/100 66/100 64/100 TECH

Percentile Scorecard

ILMNTECHBIO

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisILMNTECHBIO
Valuation 50 #115 of 227 59 #94 of 227 78 #51 of 227
Growth 46 #119 of 219 40 #131 of 219 21 #173 of 219
Profitability 97 #8 of 205 94 #14 of 205 72 #59 of 205
Financial Health 51 #116 of 237 87 #32 of 237 69 #75 of 237
Shareholder Returns 83 #24 of 135 52 #66 of 135 82 #25 of 135
Overall 65 66 64
  • ILMN ranked among 247 companies in Medical Devices and Diagnostics
  • TECH ranked among 247 companies in Medical Devices and Diagnostics
  • BIO ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodILMNTECHBIOSPY
1 month +6.2%+0.2%+2.1% +0.9%
3 months +48.2%+0.9%+17.9% +5.9%
6 months +139.9%+39.9%+40.2% +8.5%
Year to date +120.2%+23.6%+27.3% +13.3%
1 year +195.3%+13.7%+16.7% +12.4%
3 years +171.8%+22.1%+42.5% +88.1%
3 years, per year +39.6%+6.9%+12.5% +23.5%
5 years -28.5%-44.5%-51.5% +68.2%
5 years, per year -6.5%-11.1%-13.5% +11.0%
10 years +114.2%+187.8%+144.6% +263.4%
10 years, per year +7.9%+11.2%+9.4% +13.8%

Risk

MeasureILMNTECHBIOSPY
Volatility, 1Y 50.4%43.5%37.0% 12.7%
Downside volatility, 1Y 39.0%43.6%35.9% 12.7%
Beta vs S&P 500, 1Y 0.830.770.77 1.00
Return / volatility, 1Y 3.880.310.45 0.98
Max drawdown, 5Y -82.9%-67.0%-72.7% -25.4%
From 52-week high -1.7%0.0%-1.2% -0.9%
52-week high $293.69$72.69$390.34 $779.14
52-week low $95.03$43.30$241.71 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleILMNTECHBIO
P/E now vs peer median 52.9xmedian 28.8x 62.3xmedian 28.8x 46.4xmedian 28.8x
P/S now vs peer median 9.7xmedian 3.0x 9.3xmedian 3.0x 4.0xmedian 3.0x
EV/EBITDA now vs peer median 38.5xmedian 17.4x 32.3xmedian 17.4x —median 17.4x
P/FCF now vs peer median 46.8xmedian 25.7x 43.1xmedian 25.7x 29.2xmedian 25.7x
P/B now vs peer median 15.4xmedian 2.4x 5.4xmedian 2.4x 1.4xmedian 2.4x
PEG now vs peer median 1.75median 1.03 -4.77median 1.03 1.26median 1.03

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsILMNTECHBIO
Revenue $4.49B $1.22B $2.59B
Gross profit $2.98B $799.07M $1.34B
Operating income $882.00M $251.89M $53.10M
Net income $825.00M $181.86M $222.40M
Free cash flow $931.00M $263.22M $353.10M
R&D $960.00M $94.77M $265.70M
EPS (diluted) $5.39 $1.16 $8.29
Cash & equivalents $1.04B $264.71M $517.00M
Total debt $1.99B $200.00M $1.20B
Shares (diluted) 153.00M 157.01M 26.81M
Enterprise value $38.37B $10.55B $4.17B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricILMNTECHBIO
P/E 52.9x 62.3x 46.4x
P/FCF 46.8x 43.1x 29.2x
P/Operating cash flow 39.8x 38.8x 20.9x
P/S 9.7x 9.3x 4.0x
P/B 15.4x 5.4x 1.4x
P/Tangible book 18.0x 6.3x 1.5x
EV/EBITDA 38.5x 32.3x –
EV/EBIT 50.4x 44.8x 186.4x
EV/Revenue 9.9x 9.3x 3.8x
EV/FCF 47.7x 42.9x 28.0x
EV/Operating cash flow 40.6x 38.6x 20.1x
PEG (3Y EPS CAGR) 1.75 -4.77 1.26

Growth

14 metrics
MetricILMNTECHBIO
Revenue growth (1Y) 4.9% -0.4% 1.4%
Revenue CAGR (3Y) -1.0% 2.2% -2.2%
Gross profit growth (1Y) 4.6% 1.1% -0.4%
Gross profit CAGR (3Y) 2.9% 1.3% -3.5%
Operating income growth (1Y) -31.8% 146.3% -76.3%
Operating income CAGR (3Y) 28.3% -5.5% -47.4%
Net income growth (1Y) -34.4% 147.8% -30.3%
Net income CAGR (3Y) 30.0% -14.0% 36.1%
EPS growth (1Y) -32.7% 152.0% -29.3%
EPS CAGR (3Y) 30.1% -13.1% 36.9%
Operating cash flow growth (1Y) -5.1% 1.6% -7.8%
Operating cash flow CAGR (3Y) 38.1% 4.7% 19.8%
Free cash flow growth (1Y) -9.7% 2.6% -4.8%
Free cash flow CAGR (3Y) 105.0% 6.8% 31.9%

Profitability

14 metrics
MetricILMNTECHBIO
Gross margin 66.4% 65.8% 51.9%
EBITDA margin 25.7% 28.7% –
Operating margin 19.6% 20.7% 2.1%
Pretax margin 22.6% 19.8% 13.5%
Net margin 18.4% 15.0% 8.6%
FCF margin 20.7% 21.7% 13.6%
Operating cash flow margin 24.4% 24.0% 19.0%
Return on equity 29.9% 8.7% 3.2%
Return on assets 12.5% 7.1% 2.2%
Return on invested capital 15.1% 8.3% 0.4%
Return on capital employed 17.5% 10.5% 0.6%
Asset turnover 0.7x 0.5x 0.3x
Cash conversion (OCF / net income) 1.3x 1.6x 2.2x
Stock comp / revenue 5.9% 0.5% –

Financial Health

11 metrics
MetricILMNTECHBIO
Debt / assets 29.9% 7.7% 11.7%
Debt / equity 0.7x 0.1x 0.2x
Net debt / EBITDA 0.7x -0.2x –
Debt / FCF 2.1x 0.8x 3.4x
Liabilities / assets 57.3% 18.5% 30.0%
Equity / assets 42.7% 81.5% 70.0%
Interest coverage 8.9x 26.2x 1.1x
Current ratio 1.8x 4.5x 3.1x
Quick ratio 1.2x 2.9x 2.1x
Cash ratio 0.7x 1.6x 1.7x
Altman Z-score 8.19 15.91 3.62

Shareholder Returns

7 metrics
MetricILMNTECHBIO
Dividend yield – 0.4% –
Net buyback yield 1.2% -0.3% 1.1%
Shareholder yield 1.2% 0.1% 1.1%
Payout ratio (earnings) – 27.4% –
Payout ratio (FCF) – 19.0% –
Dividend growth (1Y) – -0.9% –
Dividend CAGR (3Y) – -0.2% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusILMNTECHBIO
Forward P/E 57.9xFY2026 33.7xFY2027 38.8xFY2026
EPS, next fiscal year $4.99FY2026 $2.16FY2027 $9.95FY2026
EPS growth, next FY +3.1%FY2026 +11.9%FY2027 +0.3%FY2026
EPS growth, the year after +25.7% +5.1% -0.2%
Revenue, next fiscal year $4.52BFY2026 $1.19BFY2027 $2.69BFY2026
Revenue growth, next FY +4.1%FY2026 -2.1%FY2027 +4.2%FY2026
Revenue growth, the year after +12.0% +13.5% -6.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersILMNTECHBIO
Held by institutions 100.0% 100.0% 89.5%
Institutions holding 933 597 403
Change in shares held, QoQ +0.0% -0.6% -2.9%
Institutions buying 463 293 177
Institutions selling 330 241 155
Buyers to sellers 1.40 1.22 1.14

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ILMNTECHBIO
ILMN 1.00 0.22 0.34
TECH 0.22 1.00 0.42
BIO 0.34 0.42 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, ILMN, TECH and BIO?

Illumina (ILMN) is the largest by market capitalisation: Illumina (ILMN) $43.61B, Bio-Techne (TECH) $11.35B, Bio-Rad Laboratories (BIO) $10.31B.

Which stock is cheaper, ILMN, TECH and BIO?

Bio-Rad Laboratories (BIO) trades on the lowest price-to-earnings ratio (Illumina (ILMN) 52.9x, Bio-Techne (TECH) 62.3x, Bio-Rad Laboratories (BIO) 46.4x). On next year's consensus earnings, Bio-Techne (TECH) is cheapest (Illumina (ILMN) 57.9x, Bio-Techne (TECH) 33.7x, Bio-Rad Laboratories (BIO) 38.8x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Illumina (ILMN) grew revenue fastest over the trailing twelve months: Illumina (ILMN) +4.9%, Bio-Techne (TECH) -0.4%, Bio-Rad Laboratories (BIO) +1.4%.

Which company is more profitable?

Illumina (ILMN) has the highest net margin (Illumina (ILMN) 18.4%, Bio-Techne (TECH) 15.0%, Bio-Rad Laboratories (BIO) 8.6%). On return on invested capital, Illumina (ILMN) leads (Illumina (ILMN) 15.1%, Bio-Techne (TECH) 8.3%, Bio-Rad Laboratories (BIO) 0.4%).

Which stock has performed better?

Over the past year Illumina (ILMN) returned the most: Illumina (ILMN) +195.3%, Bio-Techne (TECH) +13.7%, Bio-Rad Laboratories (BIO) +16.7%. Over five years, Illumina (ILMN) compounded fastest (Illumina (ILMN) -6.5%/yr, Bio-Techne (TECH) -11.1%/yr, Bio-Rad Laboratories (BIO) -13.5%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Bio-Techne (TECH) 0.44%. Illumina (ILMN) and Bio-Rad Laboratories (BIO) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Bio-Rad Laboratories (BIO) has been the steadiest (Illumina (ILMN) 50.4%, Bio-Techne (TECH) 43.5%, Bio-Rad Laboratories (BIO) 37.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ILMN, TECH and BIO?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Illumina (ILMN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.