ILMN vs QGEN vs TECH Stock Comparison

Illumina, Qiagen and Bio-Techne Prices as of Oct 27, 2026 Peers: Industry group
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ILMN Illumina, Inc.
$279.47 +3.5% 1M +178.5% 1Y
Market cap
$43.74B
P/E
53.0x
Revenue (TTM)
$4.49B
Div. yield
–
Life Sciences Tools Healthcare
4 wins
QGEN Qiagen N.V.
$50.18 +13.6% 1M -1.5% 1Y
Market cap
$10.93B
P/E
26.7x
Revenue (TTM)
$2.10B
Div. yield
–
Life Sciences Tools Healthcare
6 wins
TECH BIO-TECHNE Corp
$72.60 0.0% 1M +13.0% 1Y
Market cap
$11.33B
P/E
62.3x
Revenue (TTM)
$1.22B
Div. yield
0.00%
Life Sciences Tools Healthcare
1 win

Head to Head

11 decided of 12

Qiagen leads on 6 of the 12 questions below (Qiagen 6, Illumina 4, Bio-Techne 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionILMNQGENTECHLeader
Larger companyMarket capitalisation $43.74B $10.93B $11.33B ILMN
Cheaper on earningsLower P/E, profitable companies only 53.0x 26.7x 62.3x QGEN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 56.0x 21.4x 33.6x QGEN
Faster revenue growthRevenue growth, trailing twelve months +4.9% +3.0% -0.4% ILMN
More profitableNet margin, trailing twelve months 18.4% 19.5% 15.0% QGEN
Better return on capitalReturn on invested capital 15.1% 7.9% 8.3% ILMN
Less leveragedLower net debt / EBITDA 0.7x 1.3x -0.2x TECH
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +178.5% -1.5% +13.0% ILMN
Better 5-year returnAnnualised price return, 5 years -7.0%/yr -3.8%/yr -10.8%/yr QGEN
Less volatileAnnualised volatility, 1 year 50.4% 35.8% 43.5% QGEN
Higher overall scoreMean of the five percentile scores vs peers 66/100 71/100 66/100 QGEN

Percentile Scorecard

ILMNQGENTECH

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisILMNQGENTECH
Valuation 51 #111 of 227 76 #56 of 227 58 #96 of 227
Growth 45 #120 of 219 31 #151 of 219 40 #131 of 219
Profitability 97 #8 of 206 93 #16 of 206 94 #14 of 206
Financial Health 51 #117 of 238 63 #89 of 238 86 #34 of 238
Shareholder Returns 84 #23 of 134 94 #9 of 134 51 #66 of 134
Overall 66 71 66
  • ILMN ranked among 247 companies in Medical Devices and Diagnostics
  • QGEN ranked among 247 companies in Medical Devices and Diagnostics
  • TECH ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodILMNQGENTECHSPY
1 month +3.5%+13.6%0.0% -0.2%
3 months +44.8%+18.8%+0.7% +3.9%
6 months +120.2%+47.5%+35.7% +8.2%
Year to date +113.1%+6.0%+23.4% +12.9%
1 year +178.5%-1.5%+13.0% +12.3%
3 years +163.0%+24.5%+21.9% +87.4%
3 years, per year +38.1%+7.6%+6.8% +23.3%
5 years -30.5%-17.4%-43.6% +67.9%
5 years, per year -7.0%-3.8%-10.8% +10.9%
10 years +106.3%+74.3%+187.0% +261.1%
10 years, per year +7.5%+5.7%+11.1% +13.7%

Risk

MeasureILMNQGENTECHSPY
Volatility, 1Y 50.4%35.8%43.5% 12.7%
Downside volatility, 1Y 39.1%30.4%43.4% 12.7%
Beta vs S&P 500, 1Y 0.820.470.77 1.00
Return / volatility, 1Y 3.54-0.040.30 0.97
Max drawdown, 5Y -82.9%-48.2%-67.0% -25.4%
From 52-week high -4.8%-9.8%-0.1% -1.2%
52-week high $293.69$55.66$72.69 $779.14
52-week low $95.03$32.63$43.30 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleILMNQGENTECH
P/E now vs peer median 51.2xmedian 29.6x 26.6xmedian 29.6x 62.3xmedian 29.6x
P/S now vs peer median 9.4xmedian 2.9x 5.2xmedian 2.9x 9.3xmedian 2.9x
EV/EBITDA now vs peer median 37.3xmedian 17.4x 18.0xmedian 17.4x 32.3xmedian 17.4x
P/FCF now vs peer median 45.3xmedian 22.3x 11.0xmedian 22.3x 43.1xmedian 22.3x
P/B now vs peer median 14.9xmedian 2.3x 3.2xmedian 2.3x 5.4xmedian 2.3x
PEG now vs peer median 1.70median 1.04 3.60median 1.04 -4.77median 1.04

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsILMNQGENTECH
Revenue $4.49B $2.10B $1.22B
Gross profit $2.98B $1.31B $799.07M
Operating income $882.00M $445.43M $251.89M
Net income $825.00M $409.32M $181.86M
Free cash flow $931.00M $991.33M $263.22M
R&D $960.00M $194.67M $94.77M
EPS (diluted) $5.39 $1.87 $1.16
Cash & equivalents $1.04B $768.50M $264.71M
Total debt $1.99B $6.86B $200.00M
Shares (diluted) 153.00M 218.88M 157.01M
Enterprise value $38.51B $6.70B $10.54B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricILMNQGENTECH
P/E 51.2x 26.6x 62.3x
P/FCF 45.3x 11.0x 43.1x
P/Operating cash flow 38.5x 16.6x 38.8x
P/S 9.4x 5.2x 9.3x
P/B 14.9x 3.2x 5.4x
P/Tangible book 17.4x 3.6x 6.3x
EV/EBITDA 37.3x 18.0x 32.3x
EV/EBIT 48.8x 26.3x 44.7x
EV/Revenue 9.6x 5.6x 9.3x
EV/FCF 46.2x 11.8x 42.8x
EV/Operating cash flow 39.3x 17.9x 38.6x
PEG (3Y EPS CAGR) 1.70 3.60 -4.77

Growth

14 metrics
MetricILMNQGENTECH
Revenue growth (1Y) 4.9% 3.0% -0.4%
Revenue CAGR (3Y) -1.0% 2.0% 2.2%
Gross profit growth (1Y) 4.6% 1.7% 1.1%
Gross profit CAGR (3Y) 2.9% 1.3% 1.3%
Operating income growth (1Y) -31.8% -4.9% 146.3%
Operating income CAGR (3Y) 28.3% 3.3% -5.5%
Net income growth (1Y) -34.4% 143.9% 147.8%
Net income CAGR (3Y) 30.0% 6.7% -14.0%
EPS growth (1Y) -32.7% 12.5% 152.0%
EPS CAGR (3Y) 30.1% 7.4% -13.1%
Operating cash flow growth (1Y) -5.1% -3.0% 1.6%
Operating cash flow CAGR (3Y) 38.1% 8.0% 4.7%
Free cash flow growth (1Y) -9.7% 2.3% 2.6%
Free cash flow CAGR (3Y) 105.0% 10.5% 6.8%

Profitability

14 metrics
MetricILMNQGENTECH
Gross margin 66.4% 62.2% 65.8%
EBITDA margin 25.7% 31.0% 28.7%
Operating margin 19.6% 21.2% 20.7%
Pretax margin 22.6% 22.0% 19.8%
Net margin 18.4% 19.5% 15.0%
FCF margin 20.7% 47.2% 21.7%
Operating cash flow margin 24.4% 31.2% 24.0%
Return on equity 29.9% 12.2% 8.7%
Return on assets 12.5% 7.0% 7.1%
Return on invested capital 15.1% 7.9% 8.3%
Return on capital employed 17.5% 8.5% 10.5%
Asset turnover 0.7x 0.4x 0.5x
Cash conversion (OCF / net income) 1.3x 1.6x 1.6x
Stock comp / revenue 5.9% 2.1% 0.5%

Financial Health

11 metrics
MetricILMNQGENTECH
Debt / assets 29.9% 27.9% 7.7%
Debt / equity 0.7x 0.5x 0.1x
Net debt / EBITDA 0.7x 1.3x -0.2x
Debt / FCF 2.1x 1.7x 0.8x
Liabilities / assets 57.3% 43.0% 18.5%
Equity / assets 42.7% 57.0% 81.5%
Interest coverage 8.9x 11.3x 26.2x
Current ratio 1.8x 2.8x 4.5x
Quick ratio 1.2x 2.0x 2.9x
Cash ratio 0.7x 1.4x 1.6x
Altman Z-score 7.97 4.07 15.89

Shareholder Returns

7 metrics
MetricILMNQGENTECH
Dividend yield – 5.3% 0.4%
Net buyback yield 1.2% 0.6% -0.3%
Shareholder yield 1.2% 5.8% 0.1%
Payout ratio (earnings) – – 27.4%
Payout ratio (FCF) – – 19.0%
Dividend growth (1Y) – – -0.9%
Dividend CAGR (3Y) – – -0.2%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusILMNQGENTECH
Forward P/E 56.0xFY2026 21.4xFY2026 33.6xFY2027
EPS, next fiscal year $4.99FY2026 $2.35FY2026 $2.16FY2027
EPS growth, next FY +3.1%FY2026 -1.3%FY2026 +11.9%FY2027
EPS growth, the year after +25.7% +17.4% +5.1%
Revenue, next fiscal year $4.52BFY2026 $2.25BFY2026 $1.19BFY2027
Revenue growth, next FY +4.1%FY2026 +7.8%FY2026 -2.1%FY2027
Revenue growth, the year after +12.0% -2.8% +13.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersILMNQGENTECH
Held by institutions 100.0% 0.0% 100.0%
Institutions holding 933 1 597
Change in shares held, QoQ +0.0% – -0.6%
Institutions buying 463 0 293
Institutions selling 330 0 241
Buyers to sellers 1.40 – 1.22

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ILMNQGENTECH
ILMN 1.00 0.38 0.22
QGEN 0.38 1.00 0.30
TECH 0.22 0.30 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, ILMN, QGEN and TECH?

Illumina (ILMN) is the largest by market capitalisation: Illumina (ILMN) $43.74B, Qiagen (QGEN) $10.93B, Bio-Techne (TECH) $11.33B.

Which stock is cheaper, ILMN, QGEN and TECH?

Qiagen (QGEN) trades on the lowest price-to-earnings ratio (Illumina (ILMN) 53.0x, Qiagen (QGEN) 26.7x, Bio-Techne (TECH) 62.3x). On next year's consensus earnings, Qiagen (QGEN) is cheapest (Illumina (ILMN) 56.0x, Qiagen (QGEN) 21.4x, Bio-Techne (TECH) 33.6x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Illumina (ILMN) grew revenue fastest over the trailing twelve months: Illumina (ILMN) +4.9%, Qiagen (QGEN) +3.0%, Bio-Techne (TECH) -0.4%.

Which company is more profitable?

Qiagen (QGEN) has the highest net margin (Illumina (ILMN) 18.4%, Qiagen (QGEN) 19.5%, Bio-Techne (TECH) 15.0%). On return on invested capital, Illumina (ILMN) leads (Illumina (ILMN) 15.1%, Qiagen (QGEN) 7.9%, Bio-Techne (TECH) 8.3%).

Which stock has performed better?

Over the past year Illumina (ILMN) returned the most: Illumina (ILMN) +178.5%, Qiagen (QGEN) -1.5%, Bio-Techne (TECH) +13.0%. Over five years, Qiagen (QGEN) compounded fastest (Illumina (ILMN) -7.0%/yr, Qiagen (QGEN) -3.8%/yr, Bio-Techne (TECH) -10.8%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Illumina (ILMN) 0.00%, Qiagen (QGEN) 0.00%, Bio-Techne (TECH) 0.00%. Illumina (ILMN) and Qiagen (QGEN) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Qiagen (QGEN) has been the steadiest (Illumina (ILMN) 50.4%, Qiagen (QGEN) 35.8%, Bio-Techne (TECH) 43.5%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ILMN, QGEN and TECH?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Qiagen (QGEN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.