ILMN vs A vs TXG Stock Comparison

Illumina, Agilent Technologies and 10x Genomics Prices as of Oct 28, 2026 Peers: Industry group
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ILMN Illumina, Inc.
$288.79 +6.2% 1M +195.3% 1Y
Market cap
$43.51B
P/E
52.7x
Revenue (TTM)
$4.49B
Div. yield
–
Life Sciences Tools Healthcare
3 wins
A Agilent Technologies, Inc.
$181.54 +3.6% 1M +24.5% 1Y
Market cap
$51.12B
P/E
35.5x
Revenue (TTM)
$7.37B
Div. yield
0.01%
Life Sciences Tools Healthcare
7 wins
TXG 10x Genomics, Inc.
$83.62 -5.5% 1M +526.8% 1Y
Market cap
$10.62B
P/E
–
Revenue (TTM)
$616.91M
Div. yield
–
Life Sciences Tools Healthcare
1 win

Head to Head

11 decided of 12

Agilent Technologies leads on 7 of the 12 questions below (Agilent Technologies 7, Illumina 3, 10x Genomics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionILMNATXGLeader
Larger companyMarket capitalisation $43.51B $51.12B $10.62B A
Cheaper on earningsLower P/E, profitable companies only 52.7x 35.5x -141.4x A
Cheaper on forward earningsLower price / next fiscal year consensus EPS 57.9x 27.8x — A
Faster revenue growthRevenue growth, trailing twelve months +4.9% +8.6% -4.3% A
More profitableNet margin, trailing twelve months 18.4% 19.5% -12.2% A
Better return on capitalReturn on invested capital 15.1% 13.1% — ILMN
Less leveragedLower net debt / EBITDA 0.7x 1.1x — ILMN
Higher dividend yieldTrailing dividend yield 0.00% 0.01% 0.00% –
Better 1-year returnPrice return, last 12 months +195.3% +24.5% +526.8% TXG
Better 5-year returnAnnualised price return, 5 years -6.5%/yr +2.9%/yr -12.3%/yr A
Less volatileAnnualised volatility, 1 year 50.4% 32.4% 74.2% A
Higher overall scoreMean of the five percentile scores vs peers 65/100 62/100 61/100 ILMN

Percentile Scorecard

ILMNATXG

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisILMNATXG
Valuation 50 #115 of 227 57 #98 of 227 44 #128 of 227
Growth 46 #119 of 219 36 #140 of 219 66 #76 of 219
Profitability 97 #8 of 205 91 #19 of 205 62 #78 of 205
Financial Health 51 #116 of 237 56 #106 of 237 68 #77 of 237
Shareholder Returns 83 #24 of 135 70 #41 of 135 68 #44 of 135
Overall 65 62 61
  • ILMN ranked among 247 companies in Medical Devices and Diagnostics
  • A ranked among 247 companies in Medical Devices and Diagnostics
  • TXG ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodILMNATXGSPY
1 month +6.2%+3.6%-5.5% +0.9%
3 months +48.2%+29.4%+80.5% +5.9%
6 months +139.9%+63.1%+314.0% +8.5%
Year to date +120.2%+33.4%+412.7% +13.3%
1 year +195.3%+24.5%+526.8% +12.4%
3 years +171.8%+76.6%+129.7% +88.1%
3 years, per year +39.6%+20.9%+32.0% +23.5%
5 years -28.5%+15.3%-48.1% +68.2%
5 years, per year -6.5%+2.9%-12.3% +11.0%
10 years +114.2%+320.0%— +263.4%
10 years, per year +7.9%+15.4%— +13.8%

Risk

MeasureILMNATXGSPY
Volatility, 1Y 50.4%32.4%74.2% 12.7%
Downside volatility, 1Y 39.0%27.6%66.3% 12.7%
Beta vs S&P 500, 1Y 0.830.882.24 1.00
Return / volatility, 1Y 3.880.757.10 0.98
Max drawdown, 5Y -82.9%-39.6%-96.1% -25.4%
From 52-week high -1.7%0.0%-14.4% -0.9%
52-week high $293.69$181.54$97.74 $779.14
52-week low $95.03$110.24$12.44 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleILMNATXG
P/E now vs peer median 52.9xmedian 28.8x 35.6xmedian 28.8x -144.7xmedian 28.8x
P/S now vs peer median 9.7xmedian 3.0x 6.9xmedian 3.0x 17.7xmedian 3.0x
EV/EBITDA now vs peer median 38.5xmedian 17.4x 27.9xmedian 17.4x -244.2xmedian 17.4x
P/FCF now vs peer median 46.8xmedian 25.7x 40.4xmedian 25.7x 89.7xmedian 25.7x
P/B now vs peer median 15.4xmedian 2.4x 7.0xmedian 2.4x 13.2xmedian 2.4x
PEG now vs peer median 1.75median 1.03 3.62median 1.03 -5.39median 1.03

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsILMNATXG
Revenue $4.49B $7.37B $616.91M
Gross profit $2.98B $3.97B $432.03M
Operating income $882.00M $1.64B -$88.38M
Net income $825.00M $1.44B -$75.13M
Free cash flow $931.00M $1.27B $121.44M
R&D $960.00M $485.00M $226.80M
EPS (diluted) $5.39 $5.09 $-0.58
Cash & equivalents $1.04B $1.76B –
Total debt $1.99B $3.95B –
Shares (diluted) 153.00M 283.00M 129.98M
Enterprise value $38.28B $44.01B $10.43B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricILMNATXG
P/E 52.9x 35.6x -144.7x
P/FCF 46.8x 40.4x 89.7x
P/Operating cash flow 39.8x 31.8x 85.7x
P/S 9.7x 6.9x 17.7x
P/B 15.4x 7.0x 13.2x
P/Tangible book 18.0x 7.9x 14.3x
EV/EBITDA 38.5x 27.9x -244.2x
EV/EBIT 50.4x 32.6x -122.7x
EV/Revenue 9.9x 7.2x 17.6x
EV/FCF 47.7x 42.1x 89.3x
EV/Operating cash flow 40.6x 33.2x 85.3x
PEG (3Y EPS CAGR) 1.75 3.62 -5.39

Growth

14 metrics
MetricILMNATXG
Revenue growth (1Y) 4.9% 8.6% -4.3%
Revenue CAGR (3Y) -1.0% 1.8% 2.8%
Gross profit growth (1Y) 4.6% 11.2% -3.5%
Gross profit CAGR (3Y) 2.9% 3.7% 1.1%
Operating income growth (1Y) -31.8% 13.5% 12.1%
Operating income CAGR (3Y) 28.3% 5.1% 20.9%
Net income growth (1Y) -34.4% 18.0% 11.2%
Net income CAGR (3Y) 30.0% 8.3% 24.2%
EPS growth (1Y) -32.7% 18.9% 14.9%
EPS CAGR (3Y) 30.1% 9.8% 26.8%
Operating cash flow growth (1Y) -5.1% 7.6% 89.8%
Operating cash flow CAGR (3Y) 38.1% -1.9% 135.5%
Free cash flow growth (1Y) -9.7% 16.5% 113.5%
Free cash flow CAGR (3Y) 105.0% -3.7% 44.7%

Profitability

14 metrics
MetricILMNATXG
Gross margin 66.4% 53.8% 70.0%
EBITDA margin 25.7% 25.9% -7.2%
Operating margin 19.6% 22.2% -14.3%
Pretax margin 22.6% 22.5% -12.1%
Net margin 18.4% 19.5% -12.2%
FCF margin 20.7% 17.2% 19.7%
Operating cash flow margin 24.4% 21.8% 20.6%
Return on equity 29.9% 19.9% -9.2%
Return on assets 12.5% 10.7% -7.3%
Return on invested capital 15.1% 13.1% –
Return on capital employed 17.5% 14.6% -9.8%
Asset turnover 0.7x 0.5x 0.6x
Cash conversion (OCF / net income) 1.3x 1.1x -1.7x
Stock comp / revenue 5.9% 1.8% 16.0%

Financial Health

11 metrics
MetricILMNATXG
Debt / assets 29.9% 28.3% –
Debt / equity 0.7x 0.5x –
Net debt / EBITDA 0.7x 1.1x –
Debt / FCF 2.1x 3.1x –
Liabilities / assets 57.3% 47.3% 19.9%
Equity / assets 42.7% 52.7% 80.1%
Interest coverage 8.9x 15.5x –
Current ratio 1.8x 2.1x 5.7x
Quick ratio 1.2x 1.4x 0.8x
Cash ratio 0.7x 0.8x 0.4x
Altman Z-score 8.19 5.96 30.83

Shareholder Returns

7 metrics
MetricILMNATXG
Dividend yield – 0.6% –
Net buyback yield 1.2% 0.6% -0.1%
Shareholder yield 1.2% 1.2% -0.1%
Payout ratio (earnings) – 19.9% –
Payout ratio (FCF) – 22.6% –
Dividend growth (1Y) – 2.1% –
Dividend CAGR (3Y) – 3.1% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusILMNATXG
Forward P/E 57.9xFY2026 27.8xFY2026 –
EPS, next fiscal year $4.99FY2026 $6.54FY2026 $-0.79FY2026
EPS growth, next FY +3.1%FY2026 +17.0%FY2026 –
EPS growth, the year after +25.7% +0.3% –
Revenue, next fiscal year $4.52BFY2026 $7.87BFY2026 $580.42MFY2026
Revenue growth, next FY +4.1%FY2026 +15.3%FY2026 -9.7%FY2026
Revenue growth, the year after +12.0% -5.6% +24.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersILMNATXG
Held by institutions 100.0% 92.6% 100.0%
Institutions holding 933 1,124 389
Change in shares held, QoQ +0.0% +3.2% +2.4%
Institutions buying 463 601 197
Institutions selling 330 350 137
Buyers to sellers 1.40 1.72 1.44

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ILMNATXG
ILMN 1.00 0.48 0.52
A 0.48 1.00 0.52
TXG 0.52 0.52 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, ILMN, A and TXG?

Agilent Technologies (A) is the largest by market capitalisation: Illumina (ILMN) $43.51B, Agilent Technologies (A) $51.12B, 10x Genomics (TXG) $10.62B.

Which stock is cheaper, ILMN, A and TXG?

Agilent Technologies (A) trades on the lowest price-to-earnings ratio (Illumina (ILMN) 52.7x, Agilent Technologies (A) 35.5x, 10x Genomics (TXG) -141.4x). On next year's consensus earnings, Agilent Technologies (A) is cheapest (Illumina (ILMN) 57.9x, Agilent Technologies (A) 27.8x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Agilent Technologies (A) grew revenue fastest over the trailing twelve months: Illumina (ILMN) +4.9%, Agilent Technologies (A) +8.6%, 10x Genomics (TXG) -4.3%.

Which company is more profitable?

Agilent Technologies (A) has the highest net margin (Illumina (ILMN) 18.4%, Agilent Technologies (A) 19.5%, 10x Genomics (TXG) -12.2%). On return on invested capital, Illumina (ILMN) leads (Illumina (ILMN) 15.1%, Agilent Technologies (A) 13.1%).

Which stock has performed better?

Over the past year 10x Genomics (TXG) returned the most: Illumina (ILMN) +195.3%, Agilent Technologies (A) +24.5%, 10x Genomics (TXG) +526.8%. Over five years, Agilent Technologies (A) compounded fastest (Illumina (ILMN) -6.5%/yr, Agilent Technologies (A) +2.9%/yr, 10x Genomics (TXG) -12.3%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Illumina (ILMN) 0.00%, Agilent Technologies (A) 0.01%, 10x Genomics (TXG) 0.00%. Illumina (ILMN) and 10x Genomics (TXG) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Agilent Technologies (A) has been the steadiest (Illumina (ILMN) 50.4%, Agilent Technologies (A) 32.4%, 10x Genomics (TXG) 74.2%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ILMN, A and TXG?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Agilent Technologies (A) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.