GSK vs PFE vs TMO Stock Comparison

Gsk, Pfizer and Thermo Fisher Scientific Prices as of Nov 4, 2026 Peers: Industry group
1 more company in this comparison (JNJ) Create a free account to keep reading and compare up to 10 companies.
GSK GSK plc
$51.11 +9.8% 1M +9.2% 1Y
Market cap
$102.13B
P/E
8.1x
Revenue (TTM)
$76.96B
Div. yield
–
Pharmaceuticals Healthcare
6 wins
PFE Pfizer Inc
$30.79 +12.3% 1M +26.7% 1Y
Market cap
$172.43B
P/E
42.8x
Revenue (TTM)
$63.63B
Div. yield
0.06%
Pharmaceuticals Healthcare
5 wins

Head to Head

12 decided of 12

Gsk leads on 6 of the 12 questions below (Gsk 6, Pfizer 5, Thermo Fisher Scientific 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGSKPFETMOLeader
Larger companyMarket capitalisation $102.13B $172.43B $253.67B TMO
Cheaper on earningsLower P/E, profitable companies only 8.1x 42.8x 35.9x GSK
Cheaper on forward earningsLower price / next fiscal year consensus EPS 10.1x 10.8x 27.2x GSK
Faster revenue growthRevenue growth, trailing twelve months +82.9% +1.3% +8.3% GSK
More profitableNet margin, trailing twelve months 16.4% 6.3% 14.9% GSK
Better return on capitalReturn on invested capital — 12.3% 8.0% PFE
Less leveragedLower net debt / EBITDA — 1.9x 3.1x PFE
Higher dividend yieldTrailing dividend yield 0.00% 0.06% 0.00% PFE
Better 1-year returnPrice return, last 12 months +9.2% +26.7% +24.9% PFE
Better 5-year returnAnnualised price return, 5 years +3.3%/yr -8.7%/yr +2.7%/yr GSK
Less volatileAnnualised volatility, 1 year 26.4% 21.9% 30.0% PFE
Higher overall scoreMean of the five percentile scores vs peers 79/100 68/100 59/100 GSK

Percentile Scorecard

GSKPFETMO

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGSKPFETMO
Valuation 91 #58 of 634 95 #34 of 634 61 #90 of 229
Growth 75 #155 of 607 35 #394 of 607 39 #136 of 221
Profitability 96 #25 of 557 92 #45 of 557 81 #40 of 209
Financial Health 51 #319 of 654 27 #477 of 654 31 #166 of 240
Shareholder Returns 82 #74 of 400 90 #42 of 400 82 #27 of 146
Overall 79 68 59
  • GSK ranked among 671 companies in Pharmaceuticals and Biotechnology
  • PFE ranked among 671 companies in Pharmaceuticals and Biotechnology
  • TMO ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGSKPFETMOSPY
1 month +9.8%+12.3%+4.4% -1.0%
3 months -0.7%+19.3%+22.3% -0.4%
6 months +1.1%+16.1%+49.3% +4.5%
Year to date +4.2%+23.7%+21.8% +12.4%
1 year +9.2%+26.7%+24.9% +13.6%
3 years +48.4%-1.5%+55.3% +76.4%
3 years, per year +14.1%-0.5%+15.8% +20.8%
5 years +17.5%-36.7%+14.5% +63.7%
5 years, per year +3.3%-8.7%+2.7% +10.4%
10 years +32.3%+2.6%+381.7% +267.7%
10 years, per year +2.8%+0.3%+17.0% +13.9%

Risk

MeasureGSKPFETMOSPY
Volatility, 1Y 26.4%21.9%30.0% 12.8%
Downside volatility, 1Y 24.1%21.3%28.6% 12.7%
Beta vs S&P 500, 1Y 0.260.210.64 1.00
Return / volatility, 1Y 0.351.220.83 1.06
Max drawdown, 5Y -38.8%-64.8%-41.5% -25.4%
From 52-week high -16.5%0.0%-0.5% -1.6%
52-week high $61.18$30.79$709.29 $779.14
52-week low $46.11$23.67$438.34 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGSKPFETMO
P/E now vs peer median 8.2xmedian 18.0x 43.5xmedian 18.0x 37.0xmedian 28.5x
P/S now vs peer median 1.4xmedian 9.1x 2.8xmedian 9.1x 5.5xmedian 2.9x
EV/EBITDA now vs peer median —median 16.2x 8.6xmedian 16.2x 25.7xmedian 18.5x
P/FCF now vs peer median —median 21.7x 14.9xmedian 21.7x 34.4xmedian 26.7x
P/B now vs peer median 4.5xmedian 2.2x 2.0xmedian 2.2x 4.8xmedian 2.3x
PEG now vs peer median 0.44median 0.38 -1.57median 0.38 4.89median 0.93

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGSKPFETMO
Revenue $76.96B $63.63B $47.35B
Gross profit $56.19B $46.69B $19.45B
Operating income $17.15B $19.40B $8.47B
Net income $2.75B $4.06B $7.09B
Free cash flow – $11.79B $7.60B
R&D $19.61B $11.52B $1.40B
EPS (diluted) $6.12 $0.70 $19.06
Cash & equivalents $3.88B $1.82B $5.46B
Total debt -$31.50B $62.67B $41.37B
Shares (diluted) 2.06B 5.75B 371.00M
Enterprise value $84.97B $119.78B $230.18B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGSKPFETMO
P/E 8.2x 43.5x 37.0x
P/FCF – 14.9x 34.4x
P/Operating cash flow – 12.4x 28.1x
P/S 1.4x 2.8x 5.5x
P/B 4.5x 2.0x 4.8x
P/Tangible book -12.2x 4.0x 7.1x
EV/EBITDA – 8.6x 25.7x
EV/EBIT 4.4x 11.5x 35.1x
EV/Revenue 1.0x 3.5x 6.3x
EV/FCF – 19.0x 39.1x
EV/Operating cash flow – 15.8x 31.8x
PEG (3Y EPS CAGR) 0.44 -1.57 4.89

Growth

14 metrics
MetricGSKPFETMO
Revenue growth (1Y) 82.9% 1.3% 8.3%
Revenue CAGR (3Y) 28.3% -3.2% 2.9%
Gross profit growth (1Y) 84.8% 1.3% 7.8%
Gross profit CAGR (3Y) 29.1% 2.7% 4.0%
Operating income growth (1Y) 73.5% -4.3% 12.8%
Operating income CAGR (3Y) 20.2% 7.4% 7.2%
Net income growth (1Y) -70.9% -58.9% 7.9%
Net income CAGR (3Y) -55.5% -27.2% 6.2%
EPS growth (1Y) 75.6% -59.2% 9.7%
EPS CAGR (3Y) 18.8% -27.7% 7.6%
Operating cash flow growth (1Y) – 8.4% 21.9%
Operating cash flow CAGR (3Y) – 5.6% 4.5%
Free cash flow growth (1Y) – 13.6% 24.3%
Free cash flow CAGR (3Y) – 13.0% 5.1%

Profitability

14 metrics
MetricGSKPFETMO
Gross margin 73.0% 73.4% 41.1%
EBITDA margin – 40.7% 24.4%
Operating margin 22.3% 30.5% 17.9%
Pretax margin 20.5% 6.7% 16.7%
Net margin 16.4% 6.3% 14.9%
FCF margin – 18.5% 16.0%
Operating cash flow margin – 22.3% 19.7%
Return on equity 71.9% 4.7% 13.2%
Return on assets 19.2% 2.0% 6.2%
Return on invested capital – 12.3% 8.0%
Return on capital employed 14.8% 11.3% 8.5%
Asset turnover 0.9x 0.3x 0.4x
Cash conversion (OCF / net income) – 3.5x 1.3x
Stock comp / revenue – 1.7% 0.7%

Financial Health

11 metrics
MetricGSKPFETMO
Debt / assets -33.2% 30.6% 36.2%
Debt / equity -1.3x 0.7x 0.8x
Net debt / EBITDA – 1.9x 3.1x
Debt / FCF – 5.3x 5.4x
Liabilities / assets 74.4% 56.4% 52.1%
Equity / assets 25.6% 43.6% 47.9%
Interest coverage 10.1x – 5.5x
Current ratio -0.9x 1.4x 1.8x
Quick ratio -0.5x 0.9x 1.2x
Cash ratio -0.1x 0.4x 0.4x
Altman Z-score 3.23 2.40 4.20

Shareholder Returns

7 metrics
MetricGSKPFETMO
Dividend yield 3.5% 5.6% 0.3%
Net buyback yield – – 1.5%
Shareholder yield 3.5% 5.6% 1.8%
Payout ratio (earnings) – 241.2% 9.5%
Payout ratio (FCF) – 83.1% 8.9%
Dividend growth (1Y) – 0.9% 8.0%
Dividend CAGR (3Y) – 2.2% 10.1%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGSKPFETMO
Forward P/E 10.1xFY2026 10.8xFY2026 27.2xFY2026
EPS, next fiscal year $5.07FY2026 $2.85FY2026 $25.91FY2026
EPS growth, next FY +7.9%FY2026 -11.5%FY2026 +13.3%FY2026
EPS growth, the year after +4.7% -4.6% +2.0%
Revenue, next fiscal year $48.12BFY2026 $60.59BFY2026 $50.12BFY2026
Revenue growth, next FY +7.8%FY2026 -3.2%FY2026 +12.5%FY2026
Revenue growth, the year after +1.1% +3.9% -2.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGSKPFETMO
Held by institutions 16.0% 66.9% 90.2%
Institutions holding 1,040 2,841 2,627
Change in shares held, QoQ -7.4% +2.0% +0.8%
Institutions buying 484 1,327 1,145
Institutions selling 336 1,205 1,145
Buyers to sellers 1.44 1.10 1.00

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GSKPFETMO
GSK 1.00 0.51 0.20
PFE 0.51 1.00 0.24
TMO 0.20 0.24 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, GSK, PFE and TMO?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: Gsk (GSK) $102.13B, Pfizer (PFE) $172.43B, Thermo Fisher Scientific (TMO) $253.67B.

Which stock is cheaper, GSK, PFE and TMO?

Gsk (GSK) trades on the lowest price-to-earnings ratio (Gsk (GSK) 8.1x, Pfizer (PFE) 42.8x, Thermo Fisher Scientific (TMO) 35.9x). On next year's consensus earnings, Gsk (GSK) is cheapest (Gsk (GSK) 10.1x, Pfizer (PFE) 10.8x, Thermo Fisher Scientific (TMO) 27.2x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Gsk (GSK) grew revenue fastest over the trailing twelve months: Gsk (GSK) +82.9%, Pfizer (PFE) +1.3%, Thermo Fisher Scientific (TMO) +8.3%.

Which company is more profitable?

Gsk (GSK) has the highest net margin (Gsk (GSK) 16.4%, Pfizer (PFE) 6.3%, Thermo Fisher Scientific (TMO) 14.9%). On return on invested capital, Pfizer (PFE) leads (Pfizer (PFE) 12.3%, Thermo Fisher Scientific (TMO) 8.0%).

Which stock has performed better?

Over the past year Pfizer (PFE) returned the most: Gsk (GSK) +9.2%, Pfizer (PFE) +26.7%, Thermo Fisher Scientific (TMO) +24.9%. Over five years, Gsk (GSK) compounded fastest (Gsk (GSK) +3.3%/yr, Pfizer (PFE) -8.7%/yr, Thermo Fisher Scientific (TMO) +2.7%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Pfizer (PFE) has the highest dividend yield: Gsk (GSK) 0.00%, Pfizer (PFE) 0.06%, Thermo Fisher Scientific (TMO) 0.00%. Gsk (GSK) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Pfizer (PFE) has been the steadiest (Gsk (GSK) 26.4%, Pfizer (PFE) 21.9%, Thermo Fisher Scientific (TMO) 30.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GSK, PFE and TMO?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Gsk (GSK) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.