GRFS vs ILMN vs QGEN Stock Comparison

Grifols, Illumina and Qiagen Prices as of Nov 4, 2026 Peers: Industry group
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GRFS Grifols SA
$8.60 +16.1% 1M -6.7% 1Y
Market cap
$5.85B
P/E
12.9x
Revenue (TTM)
—
Div. yield
1.28%
Biotechnology Healthcare
3 wins
ILMN Illumina, Inc.
$226.54 -22.9% 1M +93.9% 1Y
Market cap
$34.25B
P/E
38.2x
Revenue (TTM)
$4.54B
Div. yield
–
Life Sciences Tools Healthcare
7 wins
QGEN Qiagen N.V.
$50.82 +11.0% 1M +9.3% 1Y
Market cap
$11.02B
P/E
27.0x
Revenue (TTM)
$2.10B
Div. yield
5.19%
Life Sciences Tools Healthcare
2 wins

Head to Head

12 decided of 12

Illumina leads on 7 of the 12 questions below (Illumina 7, Grifols 3, Qiagen 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGRFSILMNQGENLeader
Larger companyMarket capitalisation $5.85B $34.25B $11.02B ILMN
Cheaper on earningsLower P/E, profitable companies only 12.9x 38.2x 27.0x GRFS
Cheaper on forward earningsLower price / next fiscal year consensus EPS 9.1x 45.4x 21.6x GRFS
Faster revenue growthRevenue growth, trailing twelve months — +5.8% +3.0% ILMN
More profitableNet margin, trailing twelve months — 19.7% 19.5% ILMN
Better return on capitalReturn on invested capital — 16.6% 7.9% ILMN
Less leveragedLower net debt / EBITDA — 0.4x 1.3x ILMN
Higher dividend yieldTrailing dividend yield 1.28% — 5.19% QGEN
Better 1-year returnPrice return, last 12 months -6.7% +93.9% +9.3% ILMN
Better 5-year returnAnnualised price return, 5 years -6.8%/yr -10.6%/yr -3.4%/yr QGEN
Less volatileAnnualised volatility, 1 year 32.6% 50.2% 35.4% GRFS
Higher overall scoreMean of the five percentile scores vs peers 56/100 76/100 71/100 ILMN

Percentile Scorecard

GRFSILMNQGEN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGRFSILMNQGEN
Valuation 99 #9 of 634 59 #94 of 229 75 #58 of 229
Growth – 75 #56 of 221 30 #156 of 221
Profitability – 99 #4 of 209 93 #16 of 209
Financial Health 14 #566 of 654 61 #94 of 240 64 #86 of 240
Shareholder Returns 57 #173 of 400 84 #24 of 146 94 #10 of 146
Overall 56 76 71
  • GRFS ranked among 671 companies in Pharmaceuticals and Biotechnology
  • ILMN ranked among 248 companies in Medical Devices and Diagnostics
  • QGEN ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGRFSILMNQGENSPY
1 month +16.1%-22.9%+11.0% -1.0%
3 months +8.4%+13.3%+21.2% -0.4%
6 months +2.3%+58.9%+47.6% +4.5%
Year to date -8.0%+72.7%+7.4% +12.4%
1 year -6.7%+93.9%+9.3% +13.6%
3 years -7.6%+99.2%+16.1% +76.4%
3 years, per year -2.6%+25.8%+5.1% +20.8%
5 years -29.6%-42.9%-16.1% +63.7%
5 years, per year -6.8%-10.6%-3.4% +10.4%
10 years -41.1%+73.0%+64.8% +267.7%
10 years, per year -5.2%+5.6%+5.1% +13.9%

Risk

MeasureGRFSILMNQGENSPY
Volatility, 1Y 32.6%50.2%35.4% 12.8%
Downside volatility, 1Y 34.1%49.5%30.1% 12.7%
Beta vs S&P 500, 1Y 0.880.990.43 1.00
Return / volatility, 1Y -0.211.870.26 1.06
Max drawdown, 5Y -58.8%-82.9%-48.2% -25.4%
From 52-week high -11.5%-22.9%-8.7% -1.6%
52-week high $9.72$293.69$55.66 $779.14
52-week low $7.02$114.44$32.63 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGRFSILMNQGEN
P/E now vs peer median 12.9xmedian 18.0x 38.2xmedian 28.5x 27.0xmedian 28.5x
P/S now vs peer median 0.7xmedian 9.1x 7.5xmedian 2.9x 5.2xmedian 2.9x
EV/EBITDA now vs peer median —median 16.2x 28.1xmedian 18.5x 18.2xmedian 18.5x
P/FCF now vs peer median 8.3xmedian 21.7x 32.4xmedian 26.7x 11.1xmedian 26.7x
P/B now vs peer median 0.7xmedian 2.2x 10.9xmedian 2.3x 3.3xmedian 2.3x
PEG now vs peer median —median 0.38 0.93median 0.93 6.60median 0.93

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGRFSILMNQGEN
Revenue – $4.54B $2.10B
Gross profit – $3.08B $1.31B
Operating income – $960.00M $445.43M
Net income – $895.00M $409.32M
Free cash flow – $1.06B $991.33M
R&D – $975.00M $194.67M
EPS (diluted) – $5.85 $1.87
Cash & equivalents $969.15M $1.29B $768.50M
Total debt $11.33B $1.79B $1.64B
Shares (diluted) 681.57M 153.00M 218.88M
Enterprise value $4.93B $28.96B $6.80B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGRFSILMNQGEN
P/E 12.9x 38.2x 27.0x
P/FCF 8.3x 32.4x 11.1x
P/Operating cash flow – 27.8x 16.8x
P/S 0.7x 7.5x 5.2x
P/B 0.7x 10.9x 3.3x
P/Tangible book 1.0x 12.4x 3.7x
EV/EBITDA – 28.1x 18.2x
EV/EBIT – 36.2x 26.7x
EV/Revenue – 7.6x 5.7x
EV/FCF – 32.8x 12.0x
EV/Operating cash flow – 28.2x 18.1x
PEG (3Y EPS CAGR) – 0.93 6.60

Growth

14 metrics
MetricGRFSILMNQGEN
Revenue growth (1Y) – 5.8% 3.0%
Revenue CAGR (3Y) – -0.7% 2.0%
Gross profit growth (1Y) – 8.5% 1.7%
Gross profit CAGR (3Y) – 4.4% 1.3%
Operating income growth (1Y) – 23.1% -4.9%
Operating income CAGR (3Y) – 30.0% 3.3%
Net income growth (1Y) – 27.5% 143.9%
Net income CAGR (3Y) – 40.9% 6.7%
EPS growth (1Y) – 28.3% 6.6%
EPS CAGR (3Y) – 41.3% 4.1%
Operating cash flow growth (1Y) – 9.6% -3.0%
Operating cash flow CAGR (3Y) – 47.5% 8.0%
Free cash flow growth (1Y) – 5.7% 2.3%
Free cash flow CAGR (3Y) – 126.5% 10.5%

Profitability

14 metrics
MetricGRFSILMNQGEN
Gross margin – 67.9% 62.2%
EBITDA margin – 27.3% 31.0%
Operating margin – 21.2% 21.2%
Pretax margin – 23.3% 22.0%
Net margin – 19.7% 19.5%
FCF margin – 23.3% 47.2%
Operating cash flow margin – 27.1% 31.2%
Return on equity – 29.9% 12.2%
Return on assets – 13.3% 7.0%
Return on invested capital – 16.6% 7.9%
Return on capital employed – 17.2% 8.5%
Asset turnover – 0.7x 0.4x
Cash conversion (OCF / net income) – 1.4x 1.6x
Stock comp / revenue – 5.9% 2.1%

Financial Health

11 metrics
MetricGRFSILMNQGEN
Debt / assets 48.9% 26.3% 27.9%
Debt / equity 1.3x 0.6x 0.5x
Net debt / EBITDA – 0.4x 1.3x
Debt / FCF – 1.7x 1.7x
Liabilities / assets 61.4% 53.8% 43.0%
Equity / assets 38.6% 46.2% 57.0%
Interest coverage – 9.8x 11.3x
Current ratio 2.5x 2.6x 2.8x
Quick ratio 0.8x 1.8x 2.0x
Cash ratio 0.4x 1.2x 1.4x
Altman Z-score – 7.10 4.11

Shareholder Returns

7 metrics
MetricGRFSILMNQGEN
Dividend yield 1.3% – 5.2%
Net buyback yield – 1.1% 0.6%
Shareholder yield 1.3% 1.1% 5.8%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGRFSILMNQGEN
Forward P/E 9.1xFY2026 45.4xFY2026 21.6xFY2026
EPS, next fiscal year $0.94FY2026 $4.99FY2026 $2.35FY2026
EPS growth, next FY +10.6%FY2026 +3.1%FY2026 -1.3%FY2026
EPS growth, the year after +26.6% +25.7% +17.4%
Revenue, next fiscal year $8.88BFY2026 $4.52BFY2026 $2.25BFY2026
Revenue growth, next FY +0.0%FY2026 +4.1%FY2026 +7.8%FY2026
Revenue growth, the year after +10.3% +12.0% -2.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGRFSILMNQGEN
Held by institutions 21.0% 100.0% 67.3%
Institutions holding 168 935 338
Change in shares held, QoQ -0.5% +0.0% +16.5%
Institutions buying 75 464 216
Institutions selling 65 331 86
Buyers to sellers 1.15 1.40 2.51

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GRFSILMNQGEN
GRFS 1.00 0.09 0.17
ILMN 0.09 1.00 0.37
QGEN 0.17 0.37 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, GRFS, ILMN and QGEN?

Illumina (ILMN) is the largest by market capitalisation: Grifols (GRFS) $5.85B, Illumina (ILMN) $34.25B, Qiagen (QGEN) $11.02B.

Which stock is cheaper, GRFS, ILMN and QGEN?

Grifols (GRFS) trades on the lowest price-to-earnings ratio (Grifols (GRFS) 12.9x, Illumina (ILMN) 38.2x, Qiagen (QGEN) 27.0x). On next year's consensus earnings, Grifols (GRFS) is cheapest (Grifols (GRFS) 9.1x, Illumina (ILMN) 45.4x, Qiagen (QGEN) 21.6x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Illumina (ILMN) grew revenue fastest over the trailing twelve months: Illumina (ILMN) +5.8%, Qiagen (QGEN) +3.0%.

Which company is more profitable?

Illumina (ILMN) has the highest net margin (Illumina (ILMN) 19.7%, Qiagen (QGEN) 19.5%). On return on invested capital, Illumina (ILMN) leads (Illumina (ILMN) 16.6%, Qiagen (QGEN) 7.9%).

Which stock has performed better?

Over the past year Illumina (ILMN) returned the most: Grifols (GRFS) -6.7%, Illumina (ILMN) +93.9%, Qiagen (QGEN) +9.3%. Over five years, Qiagen (QGEN) compounded fastest (Grifols (GRFS) -6.8%/yr, Illumina (ILMN) -10.6%/yr, Qiagen (QGEN) -3.4%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Qiagen (QGEN) has the highest dividend yield: Grifols (GRFS) 1.28%, Qiagen (QGEN) 5.19%. Illumina (ILMN) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Grifols (GRFS) has been the steadiest (Grifols (GRFS) 32.6%, Illumina (ILMN) 50.2%, Qiagen (QGEN) 35.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GRFS, ILMN and QGEN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Illumina (ILMN) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.