GRFS vs GILD vs AMGN Stock Comparison

Grifols, Gilead Sciences and Amgen Prices as of Oct 28, 2026 Peers: Industry group
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GRFS Grifols SA
$8.12 +9.6% 1M -13.2% 1Y
Market cap
$5.46B
P/E
12.2x
Revenue (TTM)
—
Div. yield
–
Biotechnology Healthcare
2 wins
GILD Gilead Sciences, Inc.
$159.20 +4.6% 1M +35.1% 1Y
Market cap
$204.81B
P/E
–
Revenue (TTM)
$30.46B
Div. yield
–
Biotechnology Healthcare
2 wins
AMGN Amgen Inc
$451.83 +8.1% 1M +54.7% 1Y
Market cap
$249.26B
P/E
28.5x
Revenue (TTM)
$38.10B
Div. yield
0.02%
Biotechnology Healthcare
7 wins

Head to Head

11 decided of 12

Amgen leads on 7 of the 12 questions below (Amgen 7, Grifols 2, Gilead Sciences 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGRFSGILDAMGNLeader
Larger companyMarket capitalisation $5.46B $204.81B $249.26B AMGN
Cheaper on earningsLower P/E, profitable companies only 12.2x -63.2x 28.5x GRFS
Cheaper on forward earningsLower price / next fiscal year consensus EPS 8.6x — 20.7x GRFS
Faster revenue growthRevenue growth, trailing twelve months — +5.5% +9.1% AMGN
More profitableNet margin, trailing twelve months — -10.6% 23.0% AMGN
Better return on capitalReturn on invested capital — -6.0% 14.3% AMGN
Less leveragedLower net debt / EBITDA — 87.7x 2.7x AMGN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.02% –
Better 1-year returnPrice return, last 12 months -13.2% +35.1% +54.7% AMGN
Better 5-year returnAnnualised price return, 5 years -9.1%/yr +19.7%/yr +16.9%/yr GILD
Less volatileAnnualised volatility, 1 year 32.4% 26.8% 29.7% GILD
Higher overall scoreMean of the five percentile scores vs peers 56/100 61/100 66/100 AMGN

Percentile Scorecard

GRFSGILDAMGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGRFSGILDAMGN
Valuation 99 #6 of 625 91 #60 of 625 86 #91 of 625
Growth – 31 #416 of 602 62 #231 of 602
Profitability – 85 #83 of 549 95 #31 of 549
Financial Health 14 #564 of 654 21 #515 of 654 22 #510 of 654
Shareholder Returns 56 #162 of 367 77 #86 of 367 68 #118 of 367
Overall 56 61 66
  • GRFS ranked among 672 companies in Pharmaceuticals and Biotechnology
  • GILD ranked among 672 companies in Pharmaceuticals and Biotechnology
  • AMGN ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGRFSGILDAMGNSPY
1 month +9.6%+4.6%+8.1% +0.9%
3 months -0.4%+19.9%+16.6% +5.9%
6 months +2.7%+23.6%+33.7% +8.5%
Year to date -13.2%+29.7%+38.0% +13.3%
1 year -13.2%+35.1%+54.7% +12.4%
3 years +3.6%+107.8%+72.7% +88.1%
3 years, per year +1.2%+27.6%+20.0% +23.5%
5 years -38.1%+145.4%+118.3% +68.2%
5 years, per year -9.1%+19.7%+16.9% +11.0%
10 years -44.0%+115.5%+211.2% +263.4%
10 years, per year -5.6%+8.0%+12.0% +13.8%

Risk

MeasureGRFSGILDAMGNSPY
Volatility, 1Y 32.4%26.8%29.7% 12.7%
Downside volatility, 1Y 34.2%23.9%27.9% 12.7%
Beta vs S&P 500, 1Y 0.950.300.46 1.00
Return / volatility, 1Y -0.411.311.84 0.98
Max drawdown, 5Y -58.8%-29.4%-26.7% -25.4%
From 52-week high -16.5%0.0%0.0% -0.9%
52-week high $9.72$159.20$451.83 $779.14
52-week low $7.02$117.88$291.77 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGRFSGILDAMGN
P/E now vs peer median 12.2xmedian 17.4x -61.1xmedian 17.4x 27.9xmedian 17.4x
P/S now vs peer median 0.7xmedian 9.1x 6.5xmedian 9.1x 6.4xmedian 9.1x
EV/EBITDA now vs peer median —median 17.1x 838.9xmedian 17.1x 17.9xmedian 17.1x
P/FCF now vs peer median 7.8xmedian 19.0x 15.3xmedian 19.0x 24.0xmedian 19.0x
P/B now vs peer median 0.6xmedian 2.2x 16.7xmedian 2.2x 20.9xmedian 2.2x
PEG now vs peer median —median 0.34 1.63median 0.34 10.53median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGRFSGILDAMGN
Revenue – $30.46B $38.10B
Gross profit – $24.24B $26.48B
Operating income – -$2.50B $11.43B
Net income – -$3.24B $8.74B
Free cash flow – $12.94B $10.18B
R&D – $6.07B $7.63B
EPS (diluted) – $-2.61 $16.07
Cash & equivalents $969.15M $3.18B $13.99B
Total debt $44.00B $26.25B $57.30B
Shares (diluted) 681.57M 1.24B 544.00M
Enterprise value $1.80B $179.01B $204.66B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGRFSGILDAMGN
P/E 12.2x -61.1x 27.9x
P/FCF 7.8x 15.3x 24.0x
P/Operating cash flow – 14.6x 19.6x
P/S 0.7x 6.5x 6.4x
P/B 0.6x 16.7x 20.9x
P/Tangible book 1.0x -89.7x -27.8x
EV/EBITDA – 838.9x 17.9x
EV/EBIT – -88.4x 25.2x
EV/Revenue – 7.2x 7.5x
EV/FCF – 17.0x 28.3x
EV/Operating cash flow – 16.3x 23.0x
PEG (3Y EPS CAGR) – 1.63 10.53

Growth

14 metrics
MetricGRFSGILDAMGN
Revenue growth (1Y) – 5.5% 9.1%
Revenue CAGR (3Y) – 3.6% 12.7%
Gross profit growth (1Y) – 6.9% 17.6%
Gross profit CAGR (3Y) – 3.7% 10.3%
Operating income growth (1Y) – -131.0% 39.5%
Operating income CAGR (3Y) – -31.9% 6.4%
Net income growth (1Y) – -151.3% 32.1%
Net income CAGR (3Y) – -37.3% 3.1%
EPS growth (1Y) – -151.8% 31.4%
EPS CAGR (3Y) – -37.5% 2.7%
Operating cash flow growth (1Y) – 37.3% 3.9%
Operating cash flow CAGR (3Y) – 12.5% 4.9%
Free cash flow growth (1Y) – 38.1% -4.1%
Free cash flow CAGR (3Y) – 13.2% 1.7%

Profitability

14 metrics
MetricGRFSGILDAMGN
Gross margin – 79.6% 69.5%
EBITDA margin – 0.9% 42.2%
Operating margin – -8.2% 30.0%
Pretax margin – -6.4% 27.0%
Net margin – -10.6% 23.0%
FCF margin – 42.5% 26.7%
Operating cash flow margin – 44.5% 32.8%
Return on equity – -18.4% 83.8%
Return on assets – -6.1% 9.3%
Return on invested capital – -6.0% 14.3%
Return on capital employed – -6.0% 16.7%
Asset turnover – 0.6x 0.4x
Cash conversion (OCF / net income) – -4.2x 1.4x
Stock comp / revenue – 3.0% 1.3%

Financial Health

11 metrics
MetricGRFSGILDAMGN
Debt / assets 48.9% 53.2% 59.9%
Debt / equity 1.3x 2.2x 4.9x
Net debt / EBITDA – 87.7x 2.7x
Debt / FCF – 2.0x 5.6x
Liabilities / assets 61.4% 76.0% 87.8%
Equity / assets 38.6% 24.0% 12.2%
Interest coverage – -2.5x 4.3x
Current ratio 2.5x 1.3x 1.4x
Quick ratio 0.8x 0.7x 0.9x
Cash ratio 0.4x 0.3x 0.5x
Altman Z-score – 3.74 2.33

Shareholder Returns

7 metrics
MetricGRFSGILDAMGN
Dividend yield 1.4% 2.0% 2.2%
Net buyback yield – 0.6% –
Shareholder yield 1.4% 2.6% 2.2%
Payout ratio (earnings) – – 60.4%
Payout ratio (FCF) – – 51.9%
Dividend growth (1Y) – – 6.3%
Dividend CAGR (3Y) – – 6.7%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGRFSGILDAMGN
Forward P/E 8.6xFY2026 – 20.7xFY2026
EPS, next fiscal year $0.94FY2026 $-0.39FY2026 $21.81FY2026
EPS growth, next FY +10.6%FY2026 -104.8%FY2026 -0.1%FY2026
EPS growth, the year after +26.6% – +7.2%
Revenue, next fiscal year $8.88BFY2026 $28.65BFY2026 $41.51BFY2026
Revenue growth, next FY +0.0%FY2026 -2.7%FY2026 +12.9%FY2026
Revenue growth, the year after +10.3% +18.1% +2.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGRFSGILDAMGN
Held by institutions 21.0% 89.6% 82.7%
Institutions holding 166 2,290 3,160
Change in shares held, QoQ -0.5% +5.1% +4.5%
Institutions buying 73 1,113 1,452
Institutions selling 65 850 1,217
Buyers to sellers 1.12 1.31 1.19

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GRFSGILDAMGN
GRFS 1.00 0.30 0.24
GILD 0.30 1.00 0.52
AMGN 0.24 0.52 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, GRFS, GILD and AMGN?

Amgen (AMGN) is the largest by market capitalisation: Grifols (GRFS) $5.46B, Gilead Sciences (GILD) $204.81B, Amgen (AMGN) $249.26B.

Which stock is cheaper, GRFS, GILD and AMGN?

Grifols (GRFS) trades on the lowest price-to-earnings ratio (Grifols (GRFS) 12.2x, Gilead Sciences (GILD) -63.2x, Amgen (AMGN) 28.5x). On next year's consensus earnings, Grifols (GRFS) is cheapest (Grifols (GRFS) 8.6x, Amgen (AMGN) 20.7x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Amgen (AMGN) grew revenue fastest over the trailing twelve months: Gilead Sciences (GILD) +5.5%, Amgen (AMGN) +9.1%.

Which company is more profitable?

Amgen (AMGN) has the highest net margin (Gilead Sciences (GILD) -10.6%, Amgen (AMGN) 23.0%). On return on invested capital, Amgen (AMGN) leads (Gilead Sciences (GILD) -6.0%, Amgen (AMGN) 14.3%).

Which stock has performed better?

Over the past year Amgen (AMGN) returned the most: Grifols (GRFS) -13.2%, Gilead Sciences (GILD) +35.1%, Amgen (AMGN) +54.7%. Over five years, Gilead Sciences (GILD) compounded fastest (Grifols (GRFS) -9.1%/yr, Gilead Sciences (GILD) +19.7%/yr, Amgen (AMGN) +16.9%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Grifols (GRFS) 0.00%, Gilead Sciences (GILD) 0.00%, Amgen (AMGN) 0.02%. Grifols (GRFS) and Gilead Sciences (GILD) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Gilead Sciences (GILD) has been the steadiest (Grifols (GRFS) 32.4%, Gilead Sciences (GILD) 26.8%, Amgen (AMGN) 29.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GRFS, GILD and AMGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amgen (AMGN) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.