GILD vs GRFS vs TXG Stock Comparison

Gilead Sciences, Grifols and 10x Genomics Prices as of Oct 28, 2026 Peers: Industry group
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GILD Gilead Sciences, Inc.
$159.20 +4.6% 1M +35.1% 1Y
Market cap
$201.04B
P/E
–
Revenue (TTM)
$30.46B
Div. yield
–
Biotechnology Healthcare
5 wins
GRFS Grifols SA
$8.12 +9.6% 1M -13.2% 1Y
Market cap
$5.44B
P/E
12.2x
Revenue (TTM)
—
Div. yield
–
Biotechnology Healthcare
TXG 10x Genomics, Inc.
$83.62 -5.5% 1M +526.8% 1Y
Market cap
$10.59B
P/E
–
Revenue (TTM)
$616.91M
Div. yield
–
Life Sciences Tools Healthcare
2 wins

Head to Head

7 decided of 12

Gilead Sciences leads on 5 of the 12 questions below (Gilead Sciences 5, 10x Genomics 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGILDGRFSTXGLeader
Larger companyMarket capitalisation $201.04B $5.44B $10.59B GILD
Cheaper on earningsLower P/E, profitable companies only -62.0x 12.2x -141.0x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 8.6x — –
Faster revenue growthRevenue growth, trailing twelve months +5.5% — -4.3% GILD
More profitableNet margin, trailing twelve months -10.6% — -12.2% GILD
Better return on capitalReturn on invested capital -6.0% — — –
Less leveragedLower net debt / EBITDA 87.7x — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +35.1% -13.2% +526.8% TXG
Better 5-year returnAnnualised price return, 5 years +19.7%/yr -9.1%/yr -12.3%/yr GILD
Less volatileAnnualised volatility, 1 year 26.8% 32.4% 74.2% GILD
Higher overall scoreMean of the five percentile scores vs peers 61/100 56/100 61/100 TXG

Percentile Scorecard

GILDGRFSTXG

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGILDGRFSTXG
Valuation 91 #60 of 625 99 #6 of 625 44 #128 of 227
Growth 31 #416 of 602 – 66 #76 of 219
Profitability 85 #83 of 549 – 62 #78 of 205
Financial Health 21 #515 of 654 14 #564 of 654 68 #77 of 237
Shareholder Returns 77 #86 of 367 56 #162 of 367 68 #44 of 135
Overall 61 56 61
  • GILD ranked among 672 companies in Pharmaceuticals and Biotechnology
  • GRFS ranked among 672 companies in Pharmaceuticals and Biotechnology
  • TXG ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGILDGRFSTXGSPY
1 month +4.6%+9.6%-5.5% +0.9%
3 months +19.9%-0.4%+80.5% +5.9%
6 months +23.6%+2.7%+314.0% +8.5%
Year to date +29.7%-13.2%+412.7% +13.3%
1 year +35.1%-13.2%+526.8% +12.4%
3 years +107.8%+3.6%+129.7% +88.1%
3 years, per year +27.6%+1.2%+32.0% +23.5%
5 years +145.4%-38.1%-48.1% +68.2%
5 years, per year +19.7%-9.1%-12.3% +11.0%
10 years +115.5%-44.0%— +263.4%
10 years, per year +8.0%-5.6%— +13.8%

Risk

MeasureGILDGRFSTXGSPY
Volatility, 1Y 26.8%32.4%74.2% 12.7%
Downside volatility, 1Y 23.9%34.2%66.3% 12.7%
Beta vs S&P 500, 1Y 0.300.952.24 1.00
Return / volatility, 1Y 1.31-0.417.10 0.98
Max drawdown, 5Y -29.4%-58.8%-96.1% -25.4%
From 52-week high 0.0%-16.5%-14.4% -0.9%
52-week high $159.20$9.72$97.74 $779.14
52-week low $117.88$7.02$12.44 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGILDGRFSTXG
P/E now vs peer median -61.1xmedian 17.4x 12.2xmedian 17.4x -144.7xmedian 28.8x
P/S now vs peer median 6.5xmedian 9.1x 0.7xmedian 9.1x 17.7xmedian 3.0x
EV/EBITDA now vs peer median 838.9xmedian 17.1x —median 17.1x -244.2xmedian 17.4x
P/FCF now vs peer median 15.3xmedian 19.0x 7.8xmedian 19.0x 89.7xmedian 25.7x
P/B now vs peer median 16.7xmedian 2.2x 0.6xmedian 2.2x 13.2xmedian 2.4x
PEG now vs peer median 1.63median 0.34 —median 0.34 -5.39median 1.03

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGILDGRFSTXG
Revenue $30.46B – $616.91M
Gross profit $24.24B – $432.03M
Operating income -$2.50B – -$88.38M
Net income -$3.24B – -$75.13M
Free cash flow $12.94B – $121.44M
R&D $6.07B – $226.80M
EPS (diluted) $-2.61 – $-0.58
Cash & equivalents $3.18B $969.15M –
Total debt $26.25B $44.00B –
Shares (diluted) 1.24B 681.57M 129.98M
Enterprise value $175.23B $1.79B $10.39B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGILDGRFSTXG
P/E -61.1x 12.2x -144.7x
P/FCF 15.3x 7.8x 89.7x
P/Operating cash flow 14.6x – 85.7x
P/S 6.5x 0.7x 17.7x
P/B 16.7x 0.6x 13.2x
P/Tangible book -89.7x 1.0x 14.3x
EV/EBITDA 838.9x – -244.2x
EV/EBIT -88.4x – -122.7x
EV/Revenue 7.2x – 17.6x
EV/FCF 17.0x – 89.3x
EV/Operating cash flow 16.3x – 85.3x
PEG (3Y EPS CAGR) 1.63 – -5.39

Growth

14 metrics
MetricGILDGRFSTXG
Revenue growth (1Y) 5.5% – -4.3%
Revenue CAGR (3Y) 3.6% – 2.8%
Gross profit growth (1Y) 6.9% – -3.5%
Gross profit CAGR (3Y) 3.7% – 1.1%
Operating income growth (1Y) -131.0% – 12.1%
Operating income CAGR (3Y) -31.9% – 20.9%
Net income growth (1Y) -151.3% – 11.2%
Net income CAGR (3Y) -37.3% – 24.2%
EPS growth (1Y) -151.8% – 14.9%
EPS CAGR (3Y) -37.5% – 26.8%
Operating cash flow growth (1Y) 37.3% – 89.8%
Operating cash flow CAGR (3Y) 12.5% – 135.5%
Free cash flow growth (1Y) 38.1% – 113.5%
Free cash flow CAGR (3Y) 13.2% – 44.7%

Profitability

14 metrics
MetricGILDGRFSTXG
Gross margin 79.6% – 70.0%
EBITDA margin 0.9% – -7.2%
Operating margin -8.2% – -14.3%
Pretax margin -6.4% – -12.1%
Net margin -10.6% – -12.2%
FCF margin 42.5% – 19.7%
Operating cash flow margin 44.5% – 20.6%
Return on equity -18.4% – -9.2%
Return on assets -6.1% – -7.3%
Return on invested capital -6.0% – –
Return on capital employed -6.0% – -9.8%
Asset turnover 0.6x – 0.6x
Cash conversion (OCF / net income) -4.2x – -1.7x
Stock comp / revenue 3.0% – 16.0%

Financial Health

11 metrics
MetricGILDGRFSTXG
Debt / assets 53.2% 48.9% –
Debt / equity 2.2x 1.3x –
Net debt / EBITDA 87.7x – –
Debt / FCF 2.0x – –
Liabilities / assets 76.0% 61.4% 19.9%
Equity / assets 24.0% 38.6% 80.1%
Interest coverage -2.5x – –
Current ratio 1.3x 2.5x 5.7x
Quick ratio 0.7x 0.8x 0.8x
Cash ratio 0.3x 0.4x 0.4x
Altman Z-score 3.74 – 30.83

Shareholder Returns

7 metrics
MetricGILDGRFSTXG
Dividend yield 2.0% 1.4% –
Net buyback yield 0.6% – -0.1%
Shareholder yield 2.6% 1.4% -0.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGILDGRFSTXG
Forward P/E – 8.6xFY2026 –
EPS, next fiscal year $-0.39FY2026 $0.94FY2026 $-0.79FY2026
EPS growth, next FY -104.8%FY2026 +10.6%FY2026 –
EPS growth, the year after – +26.6% –
Revenue, next fiscal year $28.65BFY2026 $8.88BFY2026 $580.42MFY2026
Revenue growth, next FY -2.7%FY2026 +0.0%FY2026 -9.7%FY2026
Revenue growth, the year after +18.1% +10.3% +24.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGILDGRFSTXG
Held by institutions 89.6% 21.0% 100.0%
Institutions holding 2,290 166 389
Change in shares held, QoQ +5.1% -0.5% +2.4%
Institutions buying 1,113 73 197
Institutions selling 850 65 137
Buyers to sellers 1.31 1.12 1.44

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GILDGRFSTXG
GILD 1.00 0.30 -0.04
GRFS 0.30 1.00 0.20
TXG -0.04 0.20 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, GILD, GRFS and TXG?

Gilead Sciences (GILD) is the largest by market capitalisation: Gilead Sciences (GILD) $201.04B, Grifols (GRFS) $5.44B, 10x Genomics (TXG) $10.59B.

Which company is growing faster?

Gilead Sciences (GILD) grew revenue fastest over the trailing twelve months: Gilead Sciences (GILD) +5.5%, 10x Genomics (TXG) -4.3%.

Which company is more profitable?

Gilead Sciences (GILD) has the highest net margin (Gilead Sciences (GILD) -10.6%, 10x Genomics (TXG) -12.2%).

Which stock has performed better?

Over the past year 10x Genomics (TXG) returned the most: Gilead Sciences (GILD) +35.1%, Grifols (GRFS) -13.2%, 10x Genomics (TXG) +526.8%. Over five years, Gilead Sciences (GILD) compounded fastest (Gilead Sciences (GILD) +19.7%/yr, Grifols (GRFS) -9.1%/yr, 10x Genomics (TXG) -12.3%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Gilead Sciences (GILD) has been the steadiest (Gilead Sciences (GILD) 26.8%, Grifols (GRFS) 32.4%, 10x Genomics (TXG) 74.2%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GILD, GRFS and TXG?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Gilead Sciences (GILD) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.