GILD vs AMGN vs REGN Stock Comparison

Gilead Sciences, Amgen and Regeneron Pharmaceuticals Prices as of Nov 2, 2026 Peers: Industry group
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GILD Gilead Sciences, Inc.
$170.33 +17.7% 1M +42.2% 1Y
Market cap
$211.38B
P/E
–
Revenue (TTM)
$30.46B
Div. yield
1.91%
Biotechnology Healthcare
2 wins
AMGN Amgen Inc
$465.45 +15.5% 1M +56.0% 1Y
Market cap
$251.62B
P/E
28.7x
Revenue (TTM)
$38.10B
Div. yield
2.14%
Biotechnology Healthcare
4 wins

Head to Head

12 decided of 12

Regeneron Pharmaceuticals leads on 6 of the 12 questions below (Regeneron Pharmaceuticals 6, Amgen 4, Gilead Sciences 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGILDAMGNREGNLeader
Larger companyMarket capitalisation $211.38B $251.62B $98.82B AMGN
Cheaper on earningsLower P/E, profitable companies only -65.3x 28.7x 22.8x REGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 21.3x 16.8x REGN
Faster revenue growthRevenue growth, trailing twelve months +5.5% +9.1% +9.3% REGN
More profitableNet margin, trailing twelve months -10.6% 23.0% 27.9% REGN
Better return on capitalReturn on invested capital -6.0% 14.3% 9.6% AMGN
Less leveragedLower net debt / EBITDA 87.7x 2.7x -1.4x REGN
Higher dividend yieldTrailing dividend yield 1.91% 2.14% 0.38% AMGN
Better 1-year returnPrice return, last 12 months +42.2% +56.0% +47.5% AMGN
Better 5-year returnAnnualised price return, 5 years +20.4%/yr +16.4%/yr +8.1%/yr GILD
Less volatileAnnualised volatility, 1 year 27.3% 29.7% 33.5% GILD
Higher overall scoreMean of the five percentile scores vs peers 60/100 66/100 71/100 REGN

Percentile Scorecard

GILDAMGNREGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGILDAMGNREGN
Valuation 90 #66 of 623 84 #98 of 623 87 #84 of 623
Growth 31 #413 of 601 62 #231 of 601 42 #348 of 601
Profitability 85 #85 of 553 94 #32 of 553 90 #54 of 553
Financial Health 21 #514 of 654 22 #508 of 654 74 #172 of 654
Shareholder Returns 74 #96 of 367 67 #121 of 367 64 #132 of 367
Overall 60 66 71
  • GILD ranked among 671 companies in Pharmaceuticals and Biotechnology
  • AMGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • REGN ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGILDAMGNREGNSPY
1 month +17.7%+15.5%+30.7% -2.3%
3 months +29.9%+22.9%+26.6% -0.7%
6 months +28.4%+43.7%+35.5% +4.8%
Year to date +38.8%+42.2%+24.5% +10.3%
1 year +42.2%+56.0%+47.5% +10.3%
3 years +108.8%+72.5%+17.7% +73.0%
3 years, per year +27.8%+19.9%+5.6% +20.1%
5 years +152.7%+113.4%+47.4% +61.9%
5 years, per year +20.4%+16.4%+8.1% +10.1%
10 years +134.9%+235.6%+179.7% +258.6%
10 years, per year +8.9%+12.9%+10.8% +13.6%

Risk

MeasureGILDAMGNREGNSPY
Volatility, 1Y 27.3%29.7%33.5% 12.8%
Downside volatility, 1Y 23.9%28.0%30.2% 12.8%
Beta vs S&P 500, 1Y 0.250.430.29 1.00
Return / volatility, 1Y 1.541.881.42 0.80
Max drawdown, 5Y -29.4%-26.7%-59.8% -25.4%
From 52-week high -0.8%-0.1%0.0% -3.5%
52-week high $171.68$466.01$961.26 $779.14
52-week low $118.15$296.30$600.66 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGILDAMGNREGN
P/E now vs peer median -65.3xmedian 17.4x 28.7xmedian 17.4x 22.8xmedian 17.4x
P/S now vs peer median 6.9xmedian 8.9x 6.6xmedian 8.9x 6.4xmedian 8.9x
EV/EBITDA now vs peer median 891.4xmedian 17.0x 18.3xmedian 17.0x 21.2xmedian 17.0x
P/FCF now vs peer median 16.3xmedian 21.4x 24.7xmedian 21.4x 26.3xmedian 21.4x
P/B now vs peer median 17.9xmedian 2.1x 21.5xmedian 2.1x 3.1xmedian 2.1x
PEG now vs peer median 1.74median 0.35 10.84median 0.35 8.58median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGILDAMGNREGN
Revenue $30.46B $38.10B $15.53B
Gross profit $24.24B $26.48B $13.18B
Operating income -$2.50B $11.43B $3.84B
Net income -$3.24B $8.74B $4.33B
Free cash flow $12.94B $10.18B $3.76B
R&D $6.07B $7.63B $6.28B
EPS (diluted) $-2.61 $16.07 $40.84
Cash & equivalents $3.18B $13.99B $2.46B
Total debt $26.25B $57.30B $1.99B
Shares (diluted) 1.24B 544.00M 106.00M
Enterprise value $185.49B $207.02B $65.02B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGILDAMGNREGN
P/E -65.3x 28.7x 22.8x
P/FCF 16.3x 24.7x 26.3x
P/Operating cash flow 15.6x 20.2x 21.1x
P/S 6.9x 6.6x 6.4x
P/B 17.9x 21.5x 3.1x
P/Tangible book -96.0x -28.6x 3.3x
EV/EBITDA 891.4x 18.3x 21.2x
EV/EBIT -93.9x 25.8x 24.1x
EV/Revenue 7.7x 7.7x 6.0x
EV/FCF 18.1x 29.0x 24.7x
EV/Operating cash flow 17.3x 23.6x 19.8x
PEG (3Y EPS CAGR) 1.74 10.84 8.58

Growth

14 metrics
MetricGILDAMGNREGN
Revenue growth (1Y) 5.5% 9.1% 9.3%
Revenue CAGR (3Y) 3.6% 12.7% 7.0%
Gross profit growth (1Y) 6.9% 17.6% 8.4%
Gross profit CAGR (3Y) 3.7% 10.3% 6.4%
Operating income growth (1Y) -131.0% 39.5% 0.1%
Operating income CAGR (3Y) -31.9% 6.4% -3.9%
Net income growth (1Y) -151.3% 32.1% -2.9%
Net income CAGR (3Y) -37.3% 3.1% 0.2%
EPS growth (1Y) -151.8% 31.4% -0.5%
EPS CAGR (3Y) -37.5% 2.7% 2.7%
Operating cash flow growth (1Y) 37.3% 3.9% -1.3%
Operating cash flow CAGR (3Y) 12.5% 4.9% -0.4%
Free cash flow growth (1Y) 38.1% -4.1% -2.4%
Free cash flow CAGR (3Y) 13.2% 1.7% -3.3%

Profitability

14 metrics
MetricGILDAMGNREGN
Gross margin 79.6% 69.5% 84.9%
EBITDA margin 0.9% 42.2% 28.1%
Operating margin -8.2% 30.0% 24.7%
Pretax margin -6.4% 27.0% 33.3%
Net margin -10.6% 23.0% 27.9%
FCF margin 42.5% 26.7% 24.2%
Operating cash flow margin 44.5% 32.8% 30.1%
Return on equity -18.4% 83.8% 13.7%
Return on assets -6.1% 9.3% 10.5%
Return on invested capital -6.0% 14.3% 9.6%
Return on capital employed -6.0% 16.7% 10.7%
Asset turnover 0.6x 0.4x 0.4x
Cash conversion (OCF / net income) -4.2x 1.4x 1.1x
Stock comp / revenue 3.0% 1.3% 6.4%

Financial Health

11 metrics
MetricGILDAMGNREGN
Debt / assets 53.2% 59.9% 4.8%
Debt / equity 2.2x 4.9x 0.1x
Net debt / EBITDA 87.7x 2.7x -1.4x
Debt / FCF 2.0x 5.6x 0.5x
Liabilities / assets 76.0% 87.8% 24.0%
Equity / assets 24.0% 12.2% 76.0%
Interest coverage -2.5x 4.3x 69.4x
Current ratio 1.3x 1.4x 3.3x
Quick ratio 0.7x 0.9x 2.6x
Cash ratio 0.3x 0.5x 1.4x
Altman Z-score 3.96 2.38 8.23

Shareholder Returns

7 metrics
MetricGILDAMGNREGN
Dividend yield 1.9% 2.1% 0.4%
Net buyback yield 0.5% – 2.6%
Shareholder yield 2.4% 2.1% 3.0%
Payout ratio (earnings) – 60.4% –
Payout ratio (FCF) – 51.9% –
Dividend growth (1Y) – 6.3% –
Dividend CAGR (3Y) – 6.7% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGILDAMGNREGN
Forward P/E – 21.3xFY2026 16.8xFY2026
EPS, next fiscal year $-0.39FY2026 $21.81FY2026 $57.08FY2026
EPS growth, next FY -104.8%FY2026 -0.1%FY2026 +28.8%FY2026
EPS growth, the year after – +7.2% +15.5%
Revenue, next fiscal year $28.65BFY2026 $41.51BFY2026 $17.05BFY2026
Revenue growth, next FY -2.7%FY2026 +12.9%FY2026 +18.9%FY2026
Revenue growth, the year after +18.1% +2.3% +13.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGILDAMGNREGN
Held by institutions 89.6% 82.7% 66.2%
Institutions holding 2,292 3,162 1,327
Change in shares held, QoQ +5.1% +4.5% +3.8%
Institutions buying 1,113 1,452 605
Institutions selling 852 1,219 534
Buyers to sellers 1.31 1.19 1.13

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GILDAMGNREGN
GILD 1.00 0.52 0.44
AMGN 0.52 1.00 0.49
REGN 0.44 0.49 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, GILD, AMGN and REGN?

Amgen (AMGN) is the largest by market capitalisation: Gilead Sciences (GILD) $211.38B, Amgen (AMGN) $251.62B, Regeneron Pharmaceuticals (REGN) $98.82B.

Which stock is cheaper, GILD, AMGN and REGN?

Regeneron Pharmaceuticals (REGN) trades on the lowest price-to-earnings ratio (Gilead Sciences (GILD) -65.3x, Amgen (AMGN) 28.7x, Regeneron Pharmaceuticals (REGN) 22.8x). On next year's consensus earnings, Regeneron Pharmaceuticals (REGN) is cheapest (Amgen (AMGN) 21.3x, Regeneron Pharmaceuticals (REGN) 16.8x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Regeneron Pharmaceuticals (REGN) grew revenue fastest over the trailing twelve months: Gilead Sciences (GILD) +5.5%, Amgen (AMGN) +9.1%, Regeneron Pharmaceuticals (REGN) +9.3%.

Which company is more profitable?

Regeneron Pharmaceuticals (REGN) has the highest net margin (Gilead Sciences (GILD) -10.6%, Amgen (AMGN) 23.0%, Regeneron Pharmaceuticals (REGN) 27.9%). On return on invested capital, Amgen (AMGN) leads (Gilead Sciences (GILD) -6.0%, Amgen (AMGN) 14.3%, Regeneron Pharmaceuticals (REGN) 9.6%).

Which stock has performed better?

Over the past year Amgen (AMGN) returned the most: Gilead Sciences (GILD) +42.2%, Amgen (AMGN) +56.0%, Regeneron Pharmaceuticals (REGN) +47.5%. Over five years, Gilead Sciences (GILD) compounded fastest (Gilead Sciences (GILD) +20.4%/yr, Amgen (AMGN) +16.4%/yr, Regeneron Pharmaceuticals (REGN) +8.1%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Amgen (AMGN) has the highest dividend yield: Gilead Sciences (GILD) 1.91%, Amgen (AMGN) 2.14%, Regeneron Pharmaceuticals (REGN) 0.38%.

Which stock is riskier?

By one-year price volatility, Gilead Sciences (GILD) has been the steadiest (Gilead Sciences (GILD) 27.3%, Amgen (AMGN) 29.7%, Regeneron Pharmaceuticals (REGN) 33.5%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GILD, AMGN and REGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Regeneron Pharmaceuticals (REGN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.