DHR vs SGMOQ vs STE Stock Comparison

Danaher, Sangamo Therapeutics and Steris Prices as of Oct 29, 2026 Peers: Industry group
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DHR Danaher Corp /De/
$236.99 +4.8% 1M +10.7% 1Y
Market cap
$166.58B
P/E
41.7x
Revenue (TTM)
$25.11B
Div. yield
0.64%
Life Sciences Tools Healthcare
3 wins
STE STERIS plc
$232.24 +10.2% 1M -1.9% 1Y
Market cap
$22.64B
P/E
28.2x
Revenue (TTM)
$6.04B
Div. yield
1.11%
Medical Devices Healthcare
9 wins

Head to Head

12 decided of 12

Steris leads on 9 of the 12 questions below (Steris 9, Danaher 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionDHRSGMOQSTELeader
Larger companyMarket capitalisation $166.58B $33.62M $22.64B DHR
Cheaper on earningsLower P/E, profitable companies only 41.7x -0.3x 28.2x STE
Cheaper on forward earningsLower price / next fiscal year consensus EPS 26.0x — 20.1x STE
Faster revenue growthRevenue growth, trailing twelve months +4.6% -31.6% +8.4% STE
More profitableNet margin, trailing twelve months 15.9% -310.8% 13.3% DHR
Better return on capitalReturn on invested capital 5.7% — 9.3% STE
Less leveragedLower net debt / EBITDA 2.9x — 0.9x STE
Higher dividend yieldTrailing dividend yield 0.64% — 1.11% STE
Better 1-year returnPrice return, last 12 months +10.7% -79.7% -1.9% DHR
Better 5-year returnAnnualised price return, 5 years -5.3%/yr -57.0%/yr -0.1%/yr STE
Less volatileAnnualised volatility, 1 year 30.6% 182.6% 26.2% STE
Higher overall scoreMean of the five percentile scores vs peers 60/100 25/100 76/100 STE

Percentile Scorecard

DHRSGMOQSTE

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisDHRSGMOQSTE
Valuation 70 #70 of 227 8 #574 of 624 84 #38 of 227
Growth 23 #169 of 218 43 #345 of 601 71 #63 of 218
Profitability 88 #26 of 202 44 #304 of 541 90 #22 of 202
Financial Health 46 #127 of 233 4 #620 of 647 62 #89 of 233
Shareholder Returns 77 #31 of 130 – 74 #34 of 130
Overall 60 25 76
  • DHR ranked among 247 companies in Medical Devices and Diagnostics
  • SGMOQ ranked among 671 companies in Pharmaceuticals and Biotechnology
  • STE ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodDHRSGMOQSTESPY
1 month +4.8%-14.3%+10.2% +0.7%
3 months +20.7%+71.4%+0.4% +3.7%
6 months +32.4%-7.7%+7.1% +7.1%
Year to date +3.5%-71.4%-8.4% +12.8%
1 year +10.7%-79.7%-1.9% +11.9%
3 years +28.0%-74.5%+11.1% +85.2%
3 years, per year +8.6%-36.6%+3.6% +22.8%
5 years -24.0%-98.5%-0.6% +67.6%
5 years, per year -5.3%-57.0%-0.1% +10.9%
10 years +203.1%-96.6%+247.0% +262.0%
10 years, per year +11.7%-28.6%+13.3% +13.7%

Risk

MeasureDHRSGMOQSTESPY
Volatility, 1Y 30.6%182.6%26.2% 12.7%
Downside volatility, 1Y 31.7%256.1%25.6% 12.6%
Beta vs S&P 500, 1Y 0.452.090.39 1.00
Return / volatility, 1Y 0.35-0.44-0.07 0.94
Max drawdown, 5Y -50.8%-99.6%-36.5% -25.4%
From 52-week high -2.1%-80.0%-13.6% -1.2%
52-week high $242.05$0.60$268.65 $779.14
52-week low $161.91$0.04$199.40 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleDHRSGMOQSTE
P/E now vs peer median 41.7xmedian 28.7x -0.3xmedian 17.8x 28.2xmedian 28.7x
P/S now vs peer median 6.6xmedian 3.0x 0.9xmedian 9.1x 3.8xmedian 3.0x
EV/EBITDA now vs peer median 24.6xmedian 17.8x -0.1xmedian 15.0x 14.7xmedian 17.8x
P/FCF now vs peer median 30.5xmedian 26.4x -0.3xmedian 21.7x 24.5xmedian 26.4x
P/B now vs peer median 3.2xmedian 2.4x -2.4xmedian 2.2x 3.1xmedian 2.4x
PEG now vs peer median -3.33median 0.99 -0.01median 0.35 0.31median 0.99

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsDHRSGMOQSTE
Revenue $25.11B $39.55M $6.04B
Gross profit $14.69B – $2.68B
Operating income $5.13B -$121.24M $1.14B
Net income $4.00B -$122.93M $808.10M
Free cash flow $5.47B -$97.29M $925.60M
R&D $1.62B $112.67M $115.10M
EPS (diluted) $5.66 $-0.44 $8.22
Cash & equivalents $4.35B $20.95M $482.30M
Total debt $26.56B – $1.89B
Shares (diluted) 707.60M 280.20M 97.90M
Enterprise value $150.40B -$80.48M $20.99B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricDHRSGMOQSTE
P/E 41.7x -0.3x 28.2x
P/FCF 30.5x -0.3x 24.5x
P/Operating cash flow 25.1x -0.3x 17.6x
P/S 6.6x 0.9x 3.8x
P/B 3.2x -2.4x 3.1x
P/Tangible book 5.3x -2.4x 4.0x
EV/EBITDA 24.6x -0.1x 14.7x
EV/EBIT 36.8x -0.1x 21.1x
EV/Revenue 7.5x 0.3x 4.0x
EV/FCF 34.5x -0.1x 26.0x
EV/Operating cash flow 28.5x -0.1x 18.7x
PEG (3Y EPS CAGR) -3.33 -0.01 0.31

Growth

14 metrics
MetricDHRSGMOQSTE
Revenue growth (1Y) 4.6% -31.6% 8.4%
Revenue CAGR (3Y) -0.5% -29.2% 9.0%
Gross profit growth (1Y) 2.6% – 9.1%
Gross profit CAGR (3Y) -0.9% – 9.6%
Operating income growth (1Y) 16.1% -16.6% 23.1%
Operating income CAGR (3Y) -7.1% 15.5% 11.2%
Net income growth (1Y) 17.3% -25.5% 24.6%
Net income CAGR (3Y) -14.3% 13.9% 89.1%
EPS growth (1Y) 19.2% 10.8% 25.7%
EPS CAGR (3Y) -12.5% 29.4% 89.8%
Operating cash flow growth (1Y) 7.6% -44.8% 1.9%
Operating cash flow CAGR (3Y) -7.6% 24.2% 16.9%
Free cash flow growth (1Y) 12.4% -44.3% 1.8%
Free cash flow CAGR (3Y) -9.0% 26.4% 23.3%

Profitability

14 metrics
MetricDHRSGMOQSTE
Gross margin 58.5% – 44.4%
EBITDA margin 30.5% -296.4% 27.0%
Operating margin 20.4% -306.5% 18.9%
Pretax margin 19.0% -312.2% 18.0%
Net margin 15.9% -310.8% 13.3%
FCF margin 21.8% -246.0% 15.3%
Operating cash flow margin 26.4% -245.8% 21.3%
Return on equity 7.6% – 11.2%
Return on assets 4.5% -165.7% 7.5%
Return on invested capital 5.7% – 9.3%
Return on capital employed 6.4% -382.1% 12.1%
Asset turnover 0.3x 0.5x 0.6x
Cash conversion (OCF / net income) 1.7x 0.8x 1.6x
Stock comp / revenue 1.2% 23.0% 1.0%

Financial Health

11 metrics
MetricDHRSGMOQSTE
Debt / assets 28.8% – 17.6%
Debt / equity 0.5x – 0.3x
Net debt / EBITDA 2.9x – 0.9x
Debt / FCF 4.9x – 2.0x
Liabilities / assets 43.1% 123.9% 32.7%
Equity / assets 56.9% -23.9% 67.3%
Interest coverage 17.6x – 18.8x
Current ratio 1.7x 0.8x 1.9x
Quick ratio 1.0x 0.5x 1.2x
Cash ratio 0.5x 0.5x 0.4x
Altman Z-score 3.77 -44.03 5.32

Shareholder Returns

7 metrics
MetricDHRSGMOQSTE
Dividend yield 0.6% – 1.1%
Net buyback yield 1.7% -220.1% 1.5%
Shareholder yield 2.4% -220.1% 2.6%
Payout ratio (earnings) – – 30.6%
Payout ratio (FCF) – – 26.7%
Dividend growth (1Y) – – 9.9%
Dividend CAGR (3Y) – – 9.7%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusDHRSGMOQSTE
Forward P/E 26.0xFY2026 – 20.1xFY2026
EPS, next fiscal year $9.11FY2026 $-0.31FY2026 $11.56FY2026
EPS growth, next FY +16.8%FY2026 – +13.7%FY2026
EPS growth, the year after +8.0% – +13.2%
Revenue, next fiscal year $27.01BFY2026 $9.62MFY2026 $6.62BFY2026
Revenue growth, next FY +9.9%FY2026 -75.7%FY2026 +11.5%FY2026
Revenue growth, the year after -1.9% +606.0% -0.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersDHRSGMOQSTE
Held by institutions 81.9% – 97.1%
Institutions holding 2,118 – 830
Change in shares held, QoQ +1.1% – +1.1%
Institutions buying 840 – 406
Institutions selling 1,015 – 300
Buyers to sellers 0.83 – 1.35

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

DHRSGMOQSTE
DHR 1.00 0.02 0.37
SGMOQ 0.02 1.00 0.04
STE 0.37 0.04 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, DHR, SGMOQ and STE?

Danaher (DHR) is the largest by market capitalisation: Danaher (DHR) $166.58B, Sangamo Therapeutics (SGMOQ) $33.62M, Steris (STE) $22.64B.

Which stock is cheaper, DHR, SGMOQ and STE?

Steris (STE) trades on the lowest price-to-earnings ratio (Danaher (DHR) 41.7x, Sangamo Therapeutics (SGMOQ) -0.3x, Steris (STE) 28.2x). On next year's consensus earnings, Steris (STE) is cheapest (Danaher (DHR) 26.0x, Steris (STE) 20.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Steris (STE) grew revenue fastest over the trailing twelve months: Danaher (DHR) +4.6%, Sangamo Therapeutics (SGMOQ) -31.6%, Steris (STE) +8.4%.

Which company is more profitable?

Danaher (DHR) has the highest net margin (Danaher (DHR) 15.9%, Sangamo Therapeutics (SGMOQ) -310.8%, Steris (STE) 13.3%). On return on invested capital, Steris (STE) leads (Danaher (DHR) 5.7%, Steris (STE) 9.3%).

Which stock has performed better?

Over the past year Danaher (DHR) returned the most: Danaher (DHR) +10.7%, Sangamo Therapeutics (SGMOQ) -79.7%, Steris (STE) -1.9%. Over five years, Steris (STE) compounded fastest (Danaher (DHR) -5.3%/yr, Sangamo Therapeutics (SGMOQ) -57.0%/yr, Steris (STE) -0.1%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Steris (STE) has the highest dividend yield: Danaher (DHR) 0.64%, Steris (STE) 1.11%. Sangamo Therapeutics (SGMOQ) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Steris (STE) has been the steadiest (Danaher (DHR) 30.6%, Sangamo Therapeutics (SGMOQ) 182.6%, Steris (STE) 26.2%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, DHR, SGMOQ and STE?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Steris (STE) leads on 9. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.