DHR vs ILMN vs RGEN Stock Comparison

Danaher, Illumina and Repligen Prices as of Nov 3, 2026 Peers: Industry group
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DHR Danaher Corp /De/
$230.08 +7.5% 1M +7.5% 1Y
Market cap
$165.27B
P/E
38.2x
Revenue (TTM)
$25.61B
Div. yield
–
Life Sciences Tools Healthcare
5 wins
ILMN Illumina, Inc.
$238.21 -12.8% 1M +98.5% 1Y
Market cap
$34.18B
P/E
38.2x
Revenue (TTM)
$4.54B
Div. yield
–
Life Sciences Tools Healthcare
4 wins
RGEN Repligen Corp
$178.27 -1.9% 1M +18.7% 1Y
Market cap
$10.06B
P/E
–
Revenue (TTM)
$805.61M
Div. yield
–
Life Sciences Tools Healthcare
2 wins

Head to Head

11 decided of 12

Danaher leads on 5 of the 12 questions below (Danaher 5, Illumina 4, Repligen 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionDHRILMNRGENLeader
Larger companyMarket capitalisation $165.27B $34.18B $10.06B DHR
Cheaper on earningsLower P/E, profitable companies only 38.2x 38.2x -852.7x DHR
Cheaper on forward earningsLower price / next fiscal year consensus EPS 25.3x 47.7x 91.9x DHR
Faster revenue growthRevenue growth, trailing twelve months +5.5% +5.8% +13.8% RGEN
More profitableNet margin, trailing twelve months 16.9% 19.7% -1.5% ILMN
Better return on capitalReturn on invested capital 5.8% 16.6% 0.0% ILMN
Less leveragedLower net debt / EBITDA 2.6x 0.4x -2.8x RGEN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +7.5% +98.5% +18.7% ILMN
Better 5-year returnAnnualised price return, 5 years -5.5%/yr -10.3%/yr -8.4%/yr DHR
Less volatileAnnualised volatility, 1 year 30.7% 50.0% 46.5% DHR
Higher overall scoreMean of the five percentile scores vs peers 60/100 75/100 56/100 ILMN

Percentile Scorecard

DHRILMNRGEN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisDHRILMNRGEN
Valuation 71 #67 of 229 58 #98 of 229 53 #109 of 229
Growth 26 #163 of 221 75 #56 of 221 25 #166 of 221
Profitability 86 #30 of 209 99 #4 of 209 66 #71 of 209
Financial Health 47 #127 of 240 61 #94 of 240 82 #45 of 240
Shareholder Returns 71 #43 of 147 81 #29 of 147 53 #70 of 147
Overall 60 75 56
  • DHR ranked among 248 companies in Medical Devices and Diagnostics
  • ILMN ranked among 248 companies in Medical Devices and Diagnostics
  • RGEN ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodDHRILMNRGENSPY
1 month +7.5%-12.8%-1.9% -2.0%
3 months +18.1%+17.3%+19.0% -2.2%
6 months +31.8%+71.3%+41.9% +4.2%
Year to date +0.5%+81.6%+8.8% +10.6%
1 year +7.5%+98.5%+18.7% +10.4%
3 years +16.3%+109.4%+18.6% +73.6%
3 years, per year +5.2%+28.0%+5.8% +20.2%
5 years -24.8%-41.9%-35.6% +61.6%
5 years, per year -5.5%-10.3%-8.4% +10.1%
10 years +200.6%+82.2%+569.2% +261.3%
10 years, per year +11.6%+6.2%+20.9% +13.7%

Risk

MeasureDHRILMNRGENSPY
Volatility, 1Y 30.7%50.0%46.5% 12.8%
Downside volatility, 1Y 31.8%49.1%46.9% 12.8%
Beta vs S&P 500, 1Y 0.481.071.26 1.00
Return / volatility, 1Y 0.241.970.40 0.81
Max drawdown, 5Y -50.8%-82.9%-64.7% -25.4%
From 52-week high -4.9%-18.9%-8.4% -3.2%
52-week high $242.05$293.69$194.57 $779.14
52-week low $161.91$114.44$102.87 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleDHRILMNRGEN
P/E now vs peer median 37.4xmedian 28.1x 40.2xmedian 28.1x -852.1xmedian 28.1x
P/S now vs peer median 6.3xmedian 2.9x 7.9xmedian 2.9x 12.5xmedian 2.9x
EV/EBITDA now vs peer median 23.3xmedian 18.0x 29.5xmedian 18.0x 89.3xmedian 18.0x
P/FCF now vs peer median 28.3xmedian 24.8x 34.1xmedian 24.8x 94.7xmedian 24.8x
P/B now vs peer median 3.0xmedian 2.3x 11.5xmedian 2.3x 4.8xmedian 2.3x
PEG now vs peer median -4.66median 0.95 0.97median 0.95 29.97median 0.95

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsDHRILMNRGEN
Revenue $25.61B $4.54B $805.61M
Gross profit $15.01B $3.08B $430.67M
Operating income $5.22B $960.00M $18.24M
Net income $4.33B $895.00M -$11.80M
Free cash flow $5.73B $1.06B $106.72M
R&D $1.67B $975.00M $57.23M
EPS (diluted) $6.13 $5.85 $-0.21
Cash & equivalents $5.68B $1.29B $726.96M
Total debt $26.48B $1.79B $555.60M
Shares (diluted) 706.80M 153.00M 56.64M
Enterprise value $144.92B $28.89B $6.84B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricDHRILMNRGEN
P/E 37.4x 40.2x -852.1x
P/FCF 28.3x 34.1x 94.7x
P/Operating cash flow 23.6x 29.3x 77.8x
P/S 6.3x 7.9x 12.5x
P/B 3.0x 11.5x 4.8x
P/Tangible book 5.0x 13.1x 5.7x
EV/EBITDA 23.3x 29.5x 89.3x
EV/EBIT 35.0x 38.0x 537.3x
EV/Revenue 7.1x 8.0x 12.2x
EV/FCF 31.9x 34.5x 91.8x
EV/Operating cash flow 26.6x 29.6x 75.5x
PEG (3Y EPS CAGR) -4.66 0.97 29.97

Growth

14 metrics
MetricDHRILMNRGEN
Revenue growth (1Y) 5.5% 5.8% 13.8%
Revenue CAGR (3Y) 1.3% -0.7% 7.3%
Gross profit growth (1Y) 3.9% 8.5% 33.0%
Gross profit CAGR (3Y) 1.2% 4.4% 13.3%
Operating income growth (1Y) 13.1% 23.1% 2,185%
Operating income CAGR (3Y) -3.8% 30.0% -40.5%
Net income growth (1Y) 23.6% 27.5% -779.2%
Net income CAGR (3Y) -9.9% 40.9% -28.4%
EPS growth (1Y) 24.8% 28.3% -777.9%
EPS CAGR (3Y) -8.0% 41.3% -28.4%
Operating cash flow growth (1Y) 8.6% 9.6% -0.8%
Operating cash flow CAGR (3Y) -5.3% 47.5% -4.0%
Free cash flow growth (1Y) 14.2% 5.7% -3.0%
Free cash flow CAGR (3Y) -5.8% 126.5% 1.8%

Profitability

14 metrics
MetricDHRILMNRGEN
Gross margin 58.6% 67.9% 53.5%
EBITDA margin 30.7% 27.3% 13.6%
Operating margin 20.4% 21.2% 2.3%
Pretax margin 18.8% 23.3% 1.0%
Net margin 16.9% 19.7% -1.5%
FCF margin 22.4% 23.3% 13.2%
Operating cash flow margin 26.8% 27.1% 16.1%
Return on equity 8.2% 29.9% -0.6%
Return on assets 4.7% 13.3% -0.4%
Return on invested capital 5.8% 16.6% 0.0%
Return on capital employed 6.2% 17.2% 0.6%
Asset turnover 0.3x 0.7x 0.3x
Cash conversion (OCF / net income) 1.6x 1.4x -11.0x
Stock comp / revenue 1.3% 5.9% 4.2%

Financial Health

11 metrics
MetricDHRILMNRGEN
Debt / assets 28.4% 26.3% 19.0%
Debt / equity 0.5x 0.6x 0.3x
Net debt / EBITDA 2.6x 0.4x -2.8x
Debt / FCF 4.6x 1.7x 5.2x
Liabilities / assets 42.5% 53.8% 28.5%
Equity / assets 57.5% 46.2% 71.5%
Interest coverage 14.5x 9.8x 0.8x
Current ratio 1.6x 2.6x 9.9x
Quick ratio 1.1x 1.8x 8.1x
Cash ratio 0.6x 1.2x 6.9x
Altman Z-score 3.72 7.39 8.22

Shareholder Returns

7 metrics
MetricDHRILMNRGEN
Dividend yield 0.7% – –
Net buyback yield 0.6% 1.0% -0.2%
Shareholder yield 1.2% 1.0% -0.2%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusDHRILMNRGEN
Forward P/E 25.3xFY2026 47.7xFY2026 91.9xFY2026
EPS, next fiscal year $9.11FY2026 $4.99FY2026 $1.94FY2026
EPS growth, next FY +16.8%FY2026 +3.1%FY2026 +13.5%FY2026
EPS growth, the year after +8.0% +25.7% +29.4%
Revenue, next fiscal year $27.01BFY2026 $4.52BFY2026 $773.94MFY2026
Revenue growth, next FY +9.9%FY2026 +4.1%FY2026 +4.8%FY2026
Revenue growth, the year after -1.9% +12.0% +35.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersDHRILMNRGEN
Held by institutions 81.9% 100.0% 100.0%
Institutions holding 2,120 935 483
Change in shares held, QoQ +1.1% +0.0% +1.2%
Institutions buying 842 464 273
Institutions selling 1,015 331 141
Buyers to sellers 0.83 1.40 1.94

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

DHRILMNRGEN
DHR 1.00 0.37 0.63
ILMN 0.37 1.00 0.46
RGEN 0.63 0.46 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, DHR, ILMN and RGEN?

Danaher (DHR) is the largest by market capitalisation: Danaher (DHR) $165.27B, Illumina (ILMN) $34.18B, Repligen (RGEN) $10.06B.

Which stock is cheaper, DHR, ILMN and RGEN?

Danaher (DHR) trades on the lowest price-to-earnings ratio (Danaher (DHR) 38.2x, Illumina (ILMN) 38.2x, Repligen (RGEN) -852.7x). On next year's consensus earnings, Danaher (DHR) is cheapest (Danaher (DHR) 25.3x, Illumina (ILMN) 47.7x, Repligen (RGEN) 91.9x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Repligen (RGEN) grew revenue fastest over the trailing twelve months: Danaher (DHR) +5.5%, Illumina (ILMN) +5.8%, Repligen (RGEN) +13.8%.

Which company is more profitable?

Illumina (ILMN) has the highest net margin (Danaher (DHR) 16.9%, Illumina (ILMN) 19.7%, Repligen (RGEN) -1.5%). On return on invested capital, Illumina (ILMN) leads (Danaher (DHR) 5.8%, Illumina (ILMN) 16.6%, Repligen (RGEN) 0.0%).

Which stock has performed better?

Over the past year Illumina (ILMN) returned the most: Danaher (DHR) +7.5%, Illumina (ILMN) +98.5%, Repligen (RGEN) +18.7%. Over five years, Danaher (DHR) compounded fastest (Danaher (DHR) -5.5%/yr, Illumina (ILMN) -10.3%/yr, Repligen (RGEN) -8.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Danaher (DHR) has been the steadiest (Danaher (DHR) 30.7%, Illumina (ILMN) 50.0%, Repligen (RGEN) 46.5%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, DHR, ILMN and RGEN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Danaher (DHR) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.