CRL vs TMO vs FTRE Stock Comparison

Charles River Laboratories International, Thermo Fisher Scientific and Fortrea Holdings Prices as of Oct 29, 2026 Peers: Industry group
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FTRE Fortrea Holdings Inc.
$23.14 +17.2% 1M +121.6% 1Y
Market cap
$2.02B
P/E
–
Revenue (TTM)
$2.67B
Div. yield
–
Contract Research Healthcare
3 wins

Head to Head

10 decided of 12

Thermo Fisher Scientific leads on 5 of the 12 questions below (Thermo Fisher Scientific 5, Fortrea Holdings 3, Charles River Laboratories International 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionCRLTMOFTRELeader
Larger companyMarket capitalisation $17.25B $258.21B $2.02B TMO
Cheaper on earningsLower P/E, profitable companies only -72.3x 36.5x -29.4x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 34.5x 27.4x 28.6x TMO
Faster revenue growthRevenue growth, trailing twelve months -0.7% +8.3% -3.4% TMO
More profitableNet margin, trailing twelve months -6.0% — -2.6% FTRE
Better return on capitalReturn on invested capital 1.6% — 0.8% CRL
Less leveragedLower net debt / EBITDA 6.3x — 9.1x CRL
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +108.6% +27.0% +121.6% FTRE
Better 5-year returnAnnualised price return, 5 years -3.5%/yr +2.3%/yr — TMO
Less volatileAnnualised volatility, 1 year 45.7% 29.8% 71.4% TMO
Higher overall scoreMean of the five percentile scores vs peers 43/100 51/100 53/100 FTRE

Percentile Scorecard

CRLTMOFTRE

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisCRLTMOFTRE
Valuation 50 #6 of 11 50 #113 of 227 90 #2 of 11
Growth 10 #10 of 11 41 #130 of 218 60 #5 of 11
Profitability 70 #4 of 11 70 #61 of 202 60 #5 of 11
Financial Health 42 #8 of 13 – 0 #13 of 13
Shareholder Returns – 44 #73 of 130 –
Overall 43 51 53
  • CRL ranked among 13 companies in Pharma Services
  • TMO ranked among 247 companies in Medical Devices and Diagnostics
  • FTRE ranked among 13 companies in Pharma Services

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodCRLTMOFTRESPY
1 month +26.8%+4.4%+17.2% +0.7%
3 months +60.2%+23.0%+21.3% +3.7%
6 months +125.1%+48.1%+101.2% +7.1%
Year to date +88.4%+22.4%+34.1% +12.8%
1 year +108.6%+27.0%+121.6% +11.9%
3 years +128.4%+63.4%-15.2% +85.2%
3 years, per year +31.7%+17.8%-5.4% +22.8%
5 years -16.2%+12.0%— +67.6%
5 years, per year -3.5%+2.3%— +10.9%
10 years +394.5%+381.8%— +262.0%
10 years, per year +17.3%+17.0%— +13.7%

Risk

MeasureCRLTMOFTRESPY
Volatility, 1Y 45.7%29.8%71.4% 12.7%
Downside volatility, 1Y 42.5%28.4%65.5% 12.6%
Beta vs S&P 500, 1Y 1.280.622.04 1.00
Return / volatility, 1Y 2.380.911.70 0.94
Max drawdown, 5Y -77.3%-41.5%-89.9% -25.4%
From 52-week high 0.0%0.0%-10.6% -1.2%
52-week high $375.83$709.29$25.88 $779.14
52-week low $149.93$438.34$8.87 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleCRLTMOFTRE
P/E now vs peer median -75.7xmedian 36.6x 37.2xmedian 28.7x -32.2xmedian 36.6x
P/S now vs peer median 4.5xmedian 2.6x 5.5xmedian 3.0x 0.8xmedian 2.6x
EV/EBITDA now vs peer median 52.5xmedian 31.1x —median 17.8x 33.5xmedian 31.1x
P/FCF now vs peer median 48.4xmedian 21.8x 34.0xmedian 26.4x 13.2xmedian 21.8x
P/B now vs peer median 6.3xmedian 3.1x 4.8xmedian 2.4x 4.2xmedian 3.1x
PEG now vs peer median 2.09median 2.05 4.91median 0.99 0.53median 2.05

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsCRLTMOFTRE
Revenue $4.00B $47.35B $2.67B
Gross profit $1.31B – $533.40M
Operating income $90.14M $8.47B $12.80M
Net income -$239.23M $7.09B -$68.70M
Free cash flow $370.61M – $169.00M
R&D – $1.40B –
EPS (diluted) $-4.97 $19.06 $-0.68
Cash & equivalents $192.03M $5.46B $220.60M
Total debt $2.62B – $1.06B
Shares (diluted) 48.02M 371.00M 101.20M
Enterprise value $16.44B $258.21B $1.31B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricCRLTMOFTRE
P/E -75.7x 37.2x -32.2x
P/FCF 48.4x 34.0x 13.2x
P/Operating cash flow 30.8x 28.1x 11.1x
P/S 4.5x 5.5x 0.8x
P/B 6.3x 4.8x 4.2x
P/Tangible book 6.9x 7.1x -56.2x
EV/EBITDA 52.5x – 33.5x
EV/EBIT 225.9x – 239.7x
EV/Revenue 5.1x 5.5x 1.2x
EV/FCF 55.0x – 18.2x
EV/Operating cash flow 35.0x 28.1x 15.2x
PEG (3Y EPS CAGR) 2.09 4.91 0.53

Growth

14 metrics
MetricCRLTMOFTRE
Revenue growth (1Y) -0.7% 8.3% -3.4%
Revenue CAGR (3Y) -1.5% 2.9% 0.4%
Gross profit growth (1Y) -0.1% – 3.9%
Gross profit CAGR (3Y) -5.5% – -8.5%
Operating income growth (1Y) -27.6% 12.8% 101.4%
Operating income CAGR (3Y) -48.2% 7.2% -43.3%
Net income growth (1Y) -268.7% 7.9% 93.2%
Net income CAGR (3Y) -35.5% 6.2% -47.8%
EPS growth (1Y) -253.8% 9.7% 93.9%
EPS CAGR (3Y) -36.2% 7.6% -60.7%
Operating cash flow growth (1Y) -26.1% 21.9% 13,353%
Operating cash flow CAGR (3Y) -2.3% 4.5% 5.2%
Free cash flow growth (1Y) -35.9% – 1,400%
Free cash flow CAGR (3Y) 8.6% – 10.8%

Profitability

14 metrics
MetricCRLTMOFTRE
Gross margin 32.7% – 20.0%
EBITDA margin 9.7% – 3.4%
Operating margin 2.3% – 0.5%
Pretax margin -4.6% – -2.0%
Net margin -6.0% – -2.6%
FCF margin 9.3% – 6.3%
Operating cash flow margin 14.6% 19.7% 7.6%
Return on equity -8.2% 13.2% -13.0%
Return on assets -3.1% 6.2% -2.5%
Return on invested capital 1.6% – 0.8%
Return on capital employed 1.4% – 0.7%
Asset turnover 0.5x 0.4x 1.0x
Cash conversion (OCF / net income) -2.4x 1.3x -2.9x
Stock comp / revenue 2.1% – 1.9%

Financial Health

11 metrics
MetricCRLTMOFTRE
Debt / assets 34.8% – 38.5%
Debt / equity 0.9x – 2.0x
Net debt / EBITDA 6.3x – 9.1x
Debt / FCF 7.1x – 6.2x
Liabilities / assets 62.2% – 80.6%
Equity / assets 37.8% 47.9% 19.4%
Interest coverage 0.8x – –
Current ratio 1.3x 1.8x 1.0x
Quick ratio 0.8x – 0.9x
Cash ratio 0.2x – 0.2x
Altman Z-score 3.18 – 0.86

Shareholder Returns

7 metrics
MetricCRLTMOFTRE
Dividend yield – 0.3% –
Net buyback yield 1.8% – –
Shareholder yield 1.8% 0.3% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusCRLTMOFTRE
Forward P/E 34.5xFY2026 27.4xFY2026 28.6xFY2026
EPS, next fiscal year $10.90FY2026 $25.91FY2026 $0.81FY2026
EPS growth, next FY +6.0%FY2026 +13.3%FY2026 +88.4%FY2026
EPS growth, the year after +20.5% +2.0% +22.2%
Revenue, next fiscal year $3.82BFY2026 $50.12BFY2026 $2.77BFY2026
Revenue growth, next FY -4.9%FY2026 +12.5%FY2026 +1.7%FY2026
Revenue growth, the year after +0.7% -2.8% -3.4%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersCRLTMOFTRE
Held by institutions 100.0% 90.2% 100.0%
Institutions holding 571 2,624 330
Change in shares held, QoQ -0.7% +0.8% -0.2%
Institutions buying 271 1,144 140
Institutions selling 204 1,144 108
Buyers to sellers 1.33 1.00 1.30

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

CRLTMOFTRE
CRL 1.00 0.65 0.55
TMO 0.65 1.00 0.52
FTRE 0.55 0.52 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, CRL, TMO and FTRE?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: Charles River Laboratories International (CRL) $17.25B, Thermo Fisher Scientific (TMO) $258.21B, Fortrea Holdings (FTRE) $2.02B.

Which company is growing faster?

Thermo Fisher Scientific (TMO) grew revenue fastest over the trailing twelve months: Charles River Laboratories International (CRL) -0.7%, Thermo Fisher Scientific (TMO) +8.3%, Fortrea Holdings (FTRE) -3.4%.

Which company is more profitable?

Fortrea Holdings (FTRE) has the highest net margin (Charles River Laboratories International (CRL) -6.0%, Fortrea Holdings (FTRE) -2.6%). On return on invested capital, Charles River Laboratories International (CRL) leads (Charles River Laboratories International (CRL) 1.6%, Fortrea Holdings (FTRE) 0.8%).

Which stock has performed better?

Over the past year Fortrea Holdings (FTRE) returned the most: Charles River Laboratories International (CRL) +108.6%, Thermo Fisher Scientific (TMO) +27.0%, Fortrea Holdings (FTRE) +121.6%. Over five years, Thermo Fisher Scientific (TMO) compounded fastest (Charles River Laboratories International (CRL) -3.5%/yr, Thermo Fisher Scientific (TMO) +2.3%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Thermo Fisher Scientific (TMO) has been the steadiest (Charles River Laboratories International (CRL) 45.7%, Thermo Fisher Scientific (TMO) 29.8%, Fortrea Holdings (FTRE) 71.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, CRL, TMO and FTRE?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Thermo Fisher Scientific (TMO) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.