CRL vs MEDP vs TMO Stock Comparison

Charles River Laboratories International, Medpace Holdings and Thermo Fisher Scientific Prices as of Nov 4, 2026 Peers: Industry group
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MEDP Medpace Holdings, Inc.
$656.77 +5.8% 1M +10.5% 1Y
Market cap
$18.37B
P/E
35.4x
Revenue (TTM)
$2.84B
Div. yield
–
Contract Research Healthcare
5 wins

Head to Head

11 decided of 12

Thermo Fisher Scientific leads on 5 of the 12 questions below (Thermo Fisher Scientific 5, Medpace Holdings 5, Charles River Laboratories International 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionCRLMEDPTMOLeader
Larger companyMarket capitalisation $15.54B $18.37B $261.60B TMO
Cheaper on earningsLower P/E, profitable companies only -65.6x 35.4x 37.0x MEDP
Cheaper on forward earningsLower price / next fiscal year consensus EPS 29.9x 36.9x 27.2x TMO
Faster revenue growthRevenue growth, trailing twelve months -0.7% +20.4% +8.3% MEDP
More profitableNet margin, trailing twelve months -6.0% 18.2% 14.9% MEDP
Better return on capitalReturn on invested capital 1.6% — 8.0% TMO
Less leveragedLower net debt / EBITDA 6.3x — 3.1x TMO
Higher dividend yieldTrailing dividend yield — — 0.26% –
Better 1-year returnPrice return, last 12 months +83.1% +10.5% +24.9% CRL
Better 5-year returnAnnualised price return, 5 years -2.8%/yr +23.8%/yr +2.7%/yr MEDP
Less volatileAnnualised volatility, 1 year 47.2% 45.8% 30.0% TMO
Higher overall scoreMean of the five percentile scores vs peers 48/100 78/100 59/100 MEDP

Percentile Scorecard

CRLMEDPTMO

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisCRLMEDPTMO
Valuation 70 #4 of 11 60 #5 of 11 61 #90 of 229
Growth 10 #10 of 11 100 #1 of 11 39 #136 of 221
Profitability 70 #4 of 11 100 #1 of 11 81 #40 of 209
Financial Health 42 #8 of 13 50 #7 of 13 31 #166 of 240
Shareholder Returns – – 82 #27 of 146
Overall 48 78 59
  • CRL ranked among 13 companies in Pharma Services
  • MEDP ranked among 13 companies in Pharma Services
  • TMO ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodCRLMEDPTMOSPY
1 month +4.7%+5.8%+4.4% -1.0%
3 months +24.9%+11.7%+22.3% -0.4%
6 months +79.2%+53.9%+49.3% +4.5%
Year to date +63.2%+16.9%+21.8% +12.4%
1 year +83.1%+10.5%+24.9% +13.6%
3 years +79.0%+139.5%+55.3% +76.4%
3 years, per year +21.4%+33.8%+15.8% +20.8%
5 years -13.2%+190.8%+14.5% +63.7%
5 years, per year -2.8%+23.8%+2.7% +10.4%
10 years +377.5%+2,020.7%+381.7% +267.7%
10 years, per year +16.9%+35.7%+17.0% +13.9%

Risk

MeasureCRLMEDPTMOSPY
Volatility, 1Y 47.2%45.8%30.0% 12.8%
Downside volatility, 1Y 45.3%53.8%28.6% 12.7%
Beta vs S&P 500, 1Y 1.240.710.64 1.00
Return / volatility, 1Y 1.760.230.83 1.06
Max drawdown, 5Y -74.7%-42.9%-41.5% -25.4%
From 52-week high -13.4%-5.2%-0.5% -1.6%
52-week high $375.83$692.68$709.29 $779.14
52-week low $149.93$393.42$438.34 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleCRLMEDPTMO
P/E now vs peer median -65.6xmedian 35.4x 35.4xmedian 35.4x 37.0xmedian 28.5x
P/S now vs peer median 3.9xmedian 2.5x 6.5xmedian 2.5x 5.5xmedian 2.9x
EV/EBITDA now vs peer median 46.3xmedian 29.5x 27.8xmedian 29.5x 25.7xmedian 18.5x
P/FCF now vs peer median 41.9xmedian 20.9x 27.5xmedian 20.9x 34.4xmedian 26.7x
P/B now vs peer median 5.5xmedian 2.8x 31.4xmedian 2.8x 4.8xmedian 2.3x
PEG now vs peer median 1.81median 1.97 1.24median 1.97 4.89median 0.93

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsCRLMEDPTMO
Revenue $4.00B $2.84B $47.35B
Gross profit $1.31B $827.16M $19.45B
Operating income $90.14M $607.14M $8.47B
Net income -$239.23M $517.83M $7.09B
Free cash flow $370.61M $667.63M $7.60B
R&D – – $1.40B
EPS (diluted) $-4.97 $18.25 $19.06
Cash & equivalents $192.03M $705.32M $5.46B
Total debt $2.62B – $41.37B
Shares (diluted) 48.02M 28.37M 371.00M
Enterprise value $14.78B $16.01B $238.24B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricCRLMEDPTMO
P/E -65.6x 35.4x 37.0x
P/FCF 41.9x 27.5x 34.4x
P/Operating cash flow 26.7x 25.4x 28.1x
P/S 3.9x 6.5x 5.5x
P/B 5.5x 31.4x 4.8x
P/Tangible book 6.0x 33.3x 7.1x
EV/EBITDA 46.3x 27.8x 25.7x
EV/EBIT 199.3x 29.1x 35.1x
EV/Revenue 4.5x 6.2x 6.3x
EV/FCF 48.5x 26.5x 39.1x
EV/Operating cash flow 30.9x 24.4x 31.8x
PEG (3Y EPS CAGR) 1.81 1.24 4.89

Growth

14 metrics
MetricCRLMEDPTMO
Revenue growth (1Y) -0.7% 20.4% 8.3%
Revenue CAGR (3Y) -1.5% 16.8% 2.9%
Gross profit growth (1Y) -0.1% 12.8% 7.8%
Gross profit CAGR (3Y) -5.5% 18.0% 4.0%
Operating income growth (1Y) -27.6% 19.7% 12.8%
Operating income CAGR (3Y) -48.2% 23.0% 7.2%
Net income growth (1Y) -268.7% 19.6% 7.9%
Net income CAGR (3Y) -35.5% 23.8% 6.2%
EPS growth (1Y) -253.8% 21.5% 9.7%
EPS CAGR (3Y) -36.2% 28.5% 7.6%
Operating cash flow growth (1Y) -26.1% 1.7% 21.9%
Operating cash flow CAGR (3Y) -2.3% 20.5% 4.5%
Free cash flow growth (1Y) -35.9% -1.4% 24.3%
Free cash flow CAGR (3Y) 8.6% 20.9% 5.1%

Profitability

14 metrics
MetricCRLMEDPTMO
Gross margin 32.7% 29.1% 41.1%
EBITDA margin 9.7% 22.4% 24.4%
Operating margin 2.3% 21.4% 17.9%
Pretax margin -4.6% 22.1% 16.7%
Net margin -6.0% 18.2% 14.9%
FCF margin 9.3% 23.5% 16.0%
Operating cash flow margin 14.6% 25.5% 19.7%
Return on equity -8.2% 101.7% 13.2%
Return on assets -3.1% 23.8% 6.2%
Return on invested capital 1.6% – 8.0%
Return on capital employed 1.4% 88.8% 8.5%
Asset turnover 0.5x 1.3x 0.4x
Cash conversion (OCF / net income) -2.4x 1.4x 1.3x
Stock comp / revenue 2.1% 0.8% 0.7%

Financial Health

11 metrics
MetricCRLMEDPTMO
Debt / assets 34.8% – 36.2%
Debt / equity 0.9x – 0.8x
Net debt / EBITDA 6.3x – 3.1x
Debt / FCF 7.1x – 5.4x
Liabilities / assets 62.2% 74.6% 52.1%
Equity / assets 37.8% 25.4% 47.9%
Interest coverage 0.8x – 5.5x
Current ratio 1.3x 0.8x 1.8x
Quick ratio 0.8x 0.8x 1.2x
Cash ratio 0.2x 0.5x 0.4x
Altman Z-score 2.88 8.16 4.20

Shareholder Returns

7 metrics
MetricCRLMEDPTMO
Dividend yield – – 0.3%
Net buyback yield 2.1% 1.3% 1.5%
Shareholder yield 2.1% 1.3% 1.8%
Payout ratio (earnings) – – 9.5%
Payout ratio (FCF) – – 8.9%
Dividend growth (1Y) – – 8.0%
Dividend CAGR (3Y) – – 10.1%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusCRLMEDPTMO
Forward P/E 29.9xFY2026 36.9xFY2026 27.2xFY2026
EPS, next fiscal year $10.90FY2026 $17.80FY2026 $25.91FY2026
EPS growth, next FY +6.0%FY2026 +16.5%FY2026 +13.3%FY2026
EPS growth, the year after +20.5% +6.2% +2.0%
Revenue, next fiscal year $3.82BFY2026 $2.94BFY2026 $50.12BFY2026
Revenue growth, next FY -4.9%FY2026 +16.4%FY2026 +12.5%FY2026
Revenue growth, the year after +0.7% +6.0% -2.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersCRLMEDPTMO
Held by institutions 100.0% 87.8% 90.2%
Institutions holding 571 695 2,627
Change in shares held, QoQ -0.7% +3.2% +0.8%
Institutions buying 271 279 1,145
Institutions selling 204 304 1,145
Buyers to sellers 1.33 0.92 1.00

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

CRLMEDPTMO
CRL 1.00 0.58 0.64
MEDP 0.58 1.00 0.63
TMO 0.64 0.63 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, CRL, MEDP and TMO?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: Charles River Laboratories International (CRL) $15.54B, Medpace Holdings (MEDP) $18.37B, Thermo Fisher Scientific (TMO) $261.60B.

Which stock is cheaper, CRL, MEDP and TMO?

Medpace Holdings (MEDP) trades on the lowest price-to-earnings ratio (Charles River Laboratories International (CRL) -65.6x, Medpace Holdings (MEDP) 35.4x, Thermo Fisher Scientific (TMO) 37.0x). On next year's consensus earnings, Thermo Fisher Scientific (TMO) is cheapest (Charles River Laboratories International (CRL) 29.9x, Medpace Holdings (MEDP) 36.9x, Thermo Fisher Scientific (TMO) 27.2x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Medpace Holdings (MEDP) grew revenue fastest over the trailing twelve months: Charles River Laboratories International (CRL) -0.7%, Medpace Holdings (MEDP) +20.4%, Thermo Fisher Scientific (TMO) +8.3%.

Which company is more profitable?

Medpace Holdings (MEDP) has the highest net margin (Charles River Laboratories International (CRL) -6.0%, Medpace Holdings (MEDP) 18.2%, Thermo Fisher Scientific (TMO) 14.9%). On return on invested capital, Thermo Fisher Scientific (TMO) leads (Charles River Laboratories International (CRL) 1.6%, Thermo Fisher Scientific (TMO) 8.0%).

Which stock has performed better?

Over the past year Charles River Laboratories International (CRL) returned the most: Charles River Laboratories International (CRL) +83.1%, Medpace Holdings (MEDP) +10.5%, Thermo Fisher Scientific (TMO) +24.9%. Over five years, Medpace Holdings (MEDP) compounded fastest (Charles River Laboratories International (CRL) -2.8%/yr, Medpace Holdings (MEDP) +23.8%/yr, Thermo Fisher Scientific (TMO) +2.7%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Thermo Fisher Scientific (TMO) 0.26%. Charles River Laboratories International (CRL) and Medpace Holdings (MEDP) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Thermo Fisher Scientific (TMO) has been the steadiest (Charles River Laboratories International (CRL) 47.2%, Medpace Holdings (MEDP) 45.8%, Thermo Fisher Scientific (TMO) 30.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, CRL, MEDP and TMO?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Thermo Fisher Scientific (TMO) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.