CAI vs SHC vs YDES Stock Comparison

Caris Life Sciences, Sotera Health and YD Bio Prices as of Oct 27, 2026 Peers: Industry group
SHC Sotera Health Co
$18.49 +0.8% 1M +10.7% 1Y
Market cap
$5.35B
P/E
32.7x
Revenue (TTM)
$1.22B
Div. yield
–
Diagnostic Labs Healthcare
5 wins
YDES YD Bio Ltd
$6.04 +5.4% 1M -64.7% 1Y
Market cap
$411.66M
P/E
–
Revenue (TTM)
—
Div. yield
–
Biotechnology Healthcare

Head to Head

11 decided of 12

Caris Life Sciences leads on 6 of the 12 questions below (Caris Life Sciences 6, Sotera Health 5). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionCAISHCYDESLeader
Larger companyMarket capitalisation $9.92B $5.35B $411.66M CAI
Cheaper on earningsLower P/E, profitable companies only 94.3x 32.7x — SHC
Cheaper on forward earningsLower price / next fiscal year consensus EPS 306.1x 20.1x — SHC
Faster revenue growthRevenue growth, trailing twelve months +85.4% +8.1% — CAI
More profitableNet margin, trailing twelve months 10.6% 13.4% — SHC
Better return on capitalReturn on invested capital 15.6% 9.1% — CAI
Less leveragedLower net debt / EBITDA -2.2x 3.3x — CAI
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +11.3% +10.7% -64.7% CAI
Better 5-year returnAnnualised price return, 5 years — -5.8%/yr -9.8%/yr SHC
Less volatileAnnualised volatility, 1 year 69.5% 28.4% 134.9% SHC
Higher overall scoreMean of the five percentile scores vs peers 70/100 59/100 — CAI

Percentile Scorecard

CAISHCYDES

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisCAISHCYDES
Valuation 23 #71 of 92 52 #45 of 92 –
Growth 99 #2 of 87 66 #30 of 87 –
Profitability 89 #10 of 86 82 #16 of 86 –
Financial Health 81 #19 of 97 37 #62 of 97 39 #403 of 656
Shareholder Returns 56 #25 of 56 – –
Overall 70 59 –
  • CAI ranked among 102 companies in Healthcare Providers
  • SHC ranked among 102 companies in Healthcare Providers
  • YDES ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodCAISHCYDESSPY
1 month +5.3%+0.8%+5.4% -0.2%
3 months +116.0%+4.1%+162.6% +3.9%
6 months +82.6%+19.0%+16.2% +8.2%
Year to date +24.8%+4.8%-50.5% +12.9%
1 year +11.3%+10.7%-64.7% +12.3%
3 years —+47.8%-45.1% +87.4%
3 years, per year —+13.9%-18.1% +23.3%
5 years —-25.6%-40.4% +67.9%
5 years, per year —-5.8%-9.8% +10.9%

Risk

MeasureCAISHCYDESSPY
Volatility, 1Y 69.5%28.4%134.9% 12.7%
Downside volatility, 1Y 69.3%27.0%132.8% 12.7%
Beta vs S&P 500, 1Y 1.391.010.35 1.00
Return / volatility, 1Y 0.160.38-0.48 0.97
Max drawdown, 5Y -63.0%-78.2%-91.8% -25.4%
From 52-week high 0.0%-5.5%-64.7% -1.2%
52-week high $33.67$19.57$17.11 $779.14
52-week low $14.55$13.13$1.90 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleCAISHCYDES
P/E now vs peer median 90.6xmedian 24.6x 32.3xmedian 24.6x —median 17.2x
P/S now vs peer median 9.6xmedian 1.6x 4.3xmedian 1.6x —median 9.0x
EV/EBITDA now vs peer median 50.6xmedian 14.6x 13.0xmedian 14.6x —median 16.3x
P/FCF now vs peer median 76.8xmedian 21.6x 46.8xmedian 21.6x —median 18.7x
P/B now vs peer median 16.1xmedian 3.2x 7.9xmedian 3.2x 95.6xmedian 2.2x
PEG now vs peer median —median 0.66 0.86median 0.66 —median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsCAISHCYDES
Revenue $989.61M $1.22B –
Gross profit $689.36M $668.51M –
Operating income $153.26M $411.34M –
Net income $105.14M $163.48M –
Free cash flow $123.96M $112.70M –
R&D $117.14M – –
EPS (diluted) $0.37 $0.57 –
Cash & equivalents $690.92M $356.72M $2.66M
Total debt $393.15M $2.14B –
Shares (diluted) 282.89M 288.15M 66.72M
Enterprise value $6.74B $4.04B $399.39M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricCAISHCYDES
P/E 90.6x 32.3x –
P/FCF 76.8x 46.8x –
P/Operating cash flow 56.4x 18.1x –
P/S 9.6x 4.3x –
P/B 16.1x 7.9x 95.6x
P/Tangible book 16.1x 13.3x 213.8x
EV/EBITDA 50.6x 13.0x –
EV/EBIT 59.5x 17.2x –
EV/Revenue 9.2x 5.8x –
EV/FCF 73.5x 62.6x –
EV/Operating cash flow 54.1x 24.2x –
PEG (3Y EPS CAGR) – 0.86 –

Growth

14 metrics
MetricCAISHCYDES
Revenue growth (1Y) 85.4% 8.1% –
Revenue CAGR (3Y) – 7.6% –
Gross profit growth (1Y) 141.2% 7.1% –
Gross profit CAGR (3Y) – 8.1% –
Operating income growth (1Y) 188.2% 21.8% –
Operating income CAGR (3Y) – 23.2% –
Net income growth (1Y) 137.7% 580.5% –
Net income CAGR (3Y) – 37.7% –
EPS growth (1Y) 103.0% 574.9% –
EPS CAGR (3Y) – 37.5% –
Operating cash flow growth (1Y) 227.3% 9.8% –
Operating cash flow CAGR (3Y) – 61.3% –
Free cash flow growth (1Y) 188.2% 0.0% –
Free cash flow CAGR (3Y) – 32.6% –

Profitability

14 metrics
MetricCAISHCYDES
Gross margin 69.7% 55.0% –
EBITDA margin 18.2% 44.6% –
Operating margin 15.5% 33.8% –
Pretax margin 10.6% 21.7% –
Net margin 10.6% 13.4% –
FCF margin 12.5% 9.3% –
Operating cash flow margin 17.0% 24.0% –
Return on equity 17.7% 25.4% –
Return on assets 8.8% 5.0% –
Return on invested capital 15.6% 9.1% –
Return on capital employed 15.3% 13.5% –
Asset turnover 0.8x 0.4x –
Cash conversion (OCF / net income) 1.6x 1.8x –
Stock comp / revenue 6.6% 3.1% –

Financial Health

11 metrics
MetricCAISHCYDES
Debt / assets 32.0% 64.7% –
Debt / equity 0.7x 3.2x –
Net debt / EBITDA -2.2x 3.3x –
Debt / FCF 3.2x 19.0x –
Liabilities / assets 51.9% 79.9% 55.5%
Equity / assets 48.1% 20.1% 44.5%
Interest coverage 3.3x – –
Current ratio 5.5x 2.8x 5.2x
Quick ratio 4.8x 2.4x 2.7x
Cash ratio 4.1x 1.5x 2.5x
Altman Z-score 8.11 1.94 –

Shareholder Returns

7 metrics
MetricCAISHCYDES
Dividend yield – – –
Net buyback yield 0.1% – –
Shareholder yield 0.1% – –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusCAISHCYDES
Forward P/E 306.1xFY2026 20.1xFY2026 –
EPS, next fiscal year $0.11FY2026 $0.92FY2026 –
EPS growth, next FY – +7.0%FY2026 –
EPS growth, the year after +236.4% +21.7% –
Revenue, next fiscal year $1.06BFY2026 $1.33BFY2026 –
Revenue growth, next FY +30.1%FY2026 +14.8%FY2026 –
Revenue growth, the year after +21.6% -4.2% –

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersCAISHCYDES
Held by institutions 52.0% 100.0% –
Institutions holding 245 316 –
Change in shares held, QoQ -6.3% +5.9% –
Institutions buying 175 220 –
Institutions selling 47 64 –
Buyers to sellers 3.72 3.44 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

CAISHCYDES
CAI 1.00 0.38 0.00
SHC 0.38 1.00 -0.01
YDES 0.00 -0.01 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, CAI, SHC and YDES?

Caris Life Sciences (CAI) is the largest by market capitalisation: Caris Life Sciences (CAI) $9.92B, Sotera Health (SHC) $5.35B, YD Bio (YDES) $411.66M.

Which stock is cheaper, CAI, SHC and YDES?

Sotera Health (SHC) trades on the lowest price-to-earnings ratio (Caris Life Sciences (CAI) 94.3x, Sotera Health (SHC) 32.7x). On next year's consensus earnings, Sotera Health (SHC) is cheapest (Caris Life Sciences (CAI) 306.1x, Sotera Health (SHC) 20.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Caris Life Sciences (CAI) grew revenue fastest over the trailing twelve months: Caris Life Sciences (CAI) +85.4%, Sotera Health (SHC) +8.1%.

Which company is more profitable?

Sotera Health (SHC) has the highest net margin (Caris Life Sciences (CAI) 10.6%, Sotera Health (SHC) 13.4%). On return on invested capital, Caris Life Sciences (CAI) leads (Caris Life Sciences (CAI) 15.6%, Sotera Health (SHC) 9.1%).

Which stock has performed better?

Over the past year Caris Life Sciences (CAI) returned the most: Caris Life Sciences (CAI) +11.3%, Sotera Health (SHC) +10.7%, YD Bio (YDES) -64.7%. Over five years, Sotera Health (SHC) compounded fastest (Sotera Health (SHC) -5.8%/yr, YD Bio (YDES) -9.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Sotera Health (SHC) has been the steadiest (Caris Life Sciences (CAI) 69.5%, Sotera Health (SHC) 28.4%, YD Bio (YDES) 134.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, CAI, SHC and YDES?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Caris Life Sciences (CAI) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.